Prohibitins are involved in protease-activated receptor 1-mediated platelet aggregation

Journal of Thrombosis and Haemostasis

Volumn 10, Issue 3, 2012, Pages 411-418

  Zhang, Y ^a,a   Wang, Y ^a,b   Xiang, Y ^a   Lee, W ^a  

^a KUNMING INSTITUTE OF ZOOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

Platelets; Prohibitin; Protease activated receptor 1; Thrombin

Indexed keywords

DIGOXIN ANTIBODY F(AB) FRAGMENT; PROHIBITIN; PROHIBITIN 1; PROHIBITIN 2; PROTEASE ACTIVATED RECEPTOR 4 ACTIVATING PEPTIDE; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE INHIBITOR; THROMBIN; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; ARTICLE; CALCIUM MOBILIZATION; CELL SECRETION; CELL STIMULATION; COIMMUNOPRECIPITATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DENSITY GRADIENT CENTRIFUGATION; FLOW CYTOMETRY; GENE DELETION; HUMAN; HUMAN TISSUE; IMMUNOPRECIPITATION; LIPID RAFT; MEGAKARYOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEOMICS; RNA INTERFERENCE; SUCROSE DENSITY CENTRIFUGATION; THROMBOCYTE AGGREGATION; THROMBOCYTE MEMBRANE;

AMPHIBIAN PROTEINS; BLOOD PLATELETS; CALCIUM; CELL LINE; CENTRIFUGATION, DENSITY GRADIENT; CHROMATOGRAPHY, AFFINITY; FLOW CYTOMETRY; HUMANS; IMMUNOPRECIPITATION; MEGAKARYOCYTES; MEMBRANE MICRODOMAINS; MICROSCOPY, CONFOCAL; OLIGOPEPTIDES; PEPTIDES; PLATELET AGGREGATION; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; RECEPTOR, PAR-1; REPRESSOR PROTEINS; RNA INTERFERENCE; SECRETORY VESICLES; THROMBIN; TRANSFECTION;

EID: 84863254516     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2011.04607.x     Document Type: Article

References (30)

1. Tavernarakis N, Driscoll M, Kyrpides NC. The SPFH domain: implicated in regulating targeted protein turnover in stomatins and other membrane-associated proteins. Trends Biochem Sci 1999; 24: 425-7.
2. Rivera-Milla E, Stuermer CA, Malaga-Trillo E. Ancient origin of reggie (flotillin), reggie-like, and other lipid-raft proteins: convergent evolution of the SPFH domain. Cell Mol Life Sci 2006; 63: 343-57.
3. Morrow IC, Parton RG. Flotillins and the PHB domain protein family: rafts, worms and anaesthetics. Traffic 2005; 6: 725-40.
4. Mishra S, Murphy LC, Nyomba BL, Murphy LJ. Prohibitin: a potential target for new therapeutics. Trends Mol Med 2005; 11: 192-7.
5. Merkwirth C, Langer T. Prohibitin function within mitochondria: essential roles for cell proliferation and cristae morphogenesis. Biochim Biophys Acta 2009; 1793: 27-32.
6. Artal-Sanz M, Tsang WY, Willems EM, Grivell LA, Lemire BD, van der Spek H, Nijtmans LG. The mitochondrial prohibitin complex is essential for embryonic viability and germline function in Caenorhabditis elegans. J Biol Chem 2003; 278: 32091-9.
7. Park SE, Xu J, Frolova A, Liao L, O'Malley BW, Katzenellenbogen BS. Genetic deletion of the repressor of estrogen receptor activity (REA) enhances the response to estrogen in target tissues in vivo. Mol Cell Biol 2005; 25: 1989-99.
8. Moebius J, Zahedi RP, Lewandrowski U, Berger C, Walter U, Sickmann A. The human platelet membrane proteome reveals several new potential membrane proteins. Mol Cell Proteomics 2005; 4: 1754-61.
9. Davi G, Patrono C. Platelet activation and atherothrombosis. N Engl J Med 2007; 357: 2482-94.
10. Brass LF. Thrombin and platelet activation. Chest 2003; 124: 18S-25S.
11. Mann KG. Thrombin formation. Chest 2003; 124: 4S-10S.
12. Coughlin SR. Thrombin signalling and protease-activated receptors. Nature 2000; 407: 258-64.
13. Ossovskaya VS, Bunnett NW. Protease-activated receptors: contribution to physiology and disease. Physiol Rev 2004; 84: 579-621.
14. Coughlin SR. Protease-activated receptors in hemostasis, thrombosis and vascular biology. J Thromb Haemost 2005; 3: 1800-14.
15. Zhang J, Zhang Y, Wan SG, Wei SS, Lee WH. Bm-TFF2, a trefoil factor protein with platelet activation activity from frog Bombina maxima skin secretions. Biochem Biophys Res Commun 2005; 330: 1027-33.
16. Zhang Y, Yu G, Wang Y, Xiang Y, Gao Q, Jiang P, Zhang J, Lee W. Activation of protease-activated receptor (PAR) 1 by frog trefoil factor (TFF) 2 and PAR4 by human TFF2. Cell Mol Life Sci 2011; 68: 3771-80.
17. Lee WH, Du XY, Lu QM, Clemetson KJ, Zhang Y. Stejnulxin, a novel snake C-type lectin-like protein from Trimeresurus stejnegeri venom is a potent platelet agonist acting specifically via GPVI. Thromb Haemost 2003; 90: 662-71.
18. Kim SO, Lim CT, Lam SC, Hall SE, Komiotis D, Venton DL, Le Breton GC. Purification of the human blood platelet thromboxane A2/prostaglandin H2 receptor protein. Biochem Pharmacol 1992; 43: 313-22.
19. Quinton TM, Kim S, Jin J, Kunapuli SP. Lipid rafts are required in Galpha(i) signaling downstream of the P2Y12 receptor during ADP-mediated platelet activation. J Thromb Haemost 2005; 3: 1036-41.
20. Lu Q, Navdaev A, Clemetson JM, Clemetson KJ. GPIb is involved in platelet aggregation induced by mucetin, a snake C-type lectin protein from Chinese habu (Trimeresurus mucrosquamatus) venom. Thromb Haemost 2004; 91: 1168-76.
21. Tomiyama Y, Kunicki TJ, Zipf TF, Ford SB, Aster RH. Response of human platelets to activating monoclonal antibodies: importance of Fc gamma RII (CD32) phenotype and level of expression. Blood 1992; 80: 2261-8.
22. Munday AD, Gaus K, Lopez JA. The platelet glycoprotein Ib-IX-V complex anchors lipid rafts to the membrane skeleton: implications for activation-dependent cytoskeletal translocation of signaling molecules. J Thromb Haemost 2010; 8: 163-72.
23. Terashima M, Kim KM, Adachi T, Nielsen PJ, Reth M, Kohler G, Lamers MC. The IgM antigen receptor of B lymphocytes is associated with prohibitin and a prohibitin-related protein. EMBO J 1994; 13: 3782-92.
24. Sharma A, Qadri A. Vi polysaccharide of Salmonella typhi targets the prohibitin family of molecules in intestinal epithelial cells and suppresses early inflammatory responses. Proc Natl Acad Sci USA 2004; 101: 17492-7.
25. Kolonin MG, Saha PK, Chan L, Pasqualini R, Arap W. Reversal of obesity by targeted ablation of adipose tissue. Nat Med 2004; 10: 625-32.
26. Browman DT, Hoegg MB, Robbins SM. The SPFH domain-containing proteins: more than lipid raft markers. Trends Cell Biol 2007; 17: 394-402.
27. Hazarika P, McCarty MF, Prieto VG, George S, Babu D, Koul D, Bar-Eli M, Duvic M. Up-regulation of Flotillin-2 is associated with melanoma progression and modulates expression of the thrombin receptor protease activated receptor 1. Cancer Res 2004; 64: 7361-9.
28. Smyth SS, McEver RP, Weyrich AS, Morrell CN, Hoffman MR, Arepally GM, French PA, Dauerman HL, Becker RC. Platelet functions beyond hemostasis. J Thromb Haemost 2009; 7: 1759-66.
29. Leger AJ, Covic L, Kuliopulos A. Protease-activated receptors in cardiovascular diseases. Circulation 2006; 114: 1070-7.
30. Ruggeri ZM. Platelets in atherothrombosis. Nat Med 2002; 8: 1227-34.