Synthetic polymer nanoparticles conjugated with FimH A from E. coli pili to emulate the bacterial mode of epithelial internalization

Journal of the American Chemical Society

Volumn 134, Issue 9, 2012, Pages 3938-3941

  Lin, Lily Yun ^a   Tiemann, Kristin M ^b   Li, Yali ^c   Pinkner, Jerome S ^b   Walker, Jennifer N ^b   Hultgren, Scott J ^b   Hunstad, David A ^b   Wooley, Karen L ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN; AMIDATION CHEMISTRY; AMPHIPHILIC BLOCK COPOLYMERS; E. COLI; EPITHELIAL CELLS; IN-VITRO; SYNTHETIC POLYMERS; UROPATHOGENIC ESCHERICHIA COLI;

BLOCK COPOLYMERS; NANOPARTICLES;

ESCHERICHIA COLI;

ADHESIN; AMPHOPHILE; COPOLYMER; FIMH A PROTEIN; NANOPARTICLE; POLYACRYLIC ACID; POLYSTYRENE; UNCLASSIFIED DRUG;

AMIDATION; ARTICLE; BACTERIUM PILUS; BLADDER EPITHELIUM; CONJUGATION; EPITHELIUM CELL; FLUORESCENCE MICROSCOPY; IN VITRO STUDY; INTERNALIZATION; MICELLE; NONHUMAN; UROPATHOGENIC ESCHERICHIA COLI;

ADHESINS, ESCHERICHIA COLI; EPITHELIAL CELLS; ESCHERICHIA COLI; FIMBRIAE PROTEINS; MODELS, MOLECULAR; NANOPARTICLES; PARTICLE SIZE; POLYMERS; SURFACE PROPERTIES;

EID: 84863233142     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja2091917     Document Type: Article

References (30)

1. Nicolle, L. E. Infect. Med. 2001, 18, 153.
2. Foxman, B. Am. J. Med. 2002, 113, 5S.
3. Andriole, V. T.; Patterson, T. F. Nat. Rev. Microbiol. 1991, 75, 359.
4. Kaper, J. B.; Nataro, J. P.; Mobley, H. L. T. Nat. Rev. Microbiol. 2004, 2, 123.
5. Jones, C. H.; Pinkner, J. S.; Roth, R.; Heuser, J.; Nicholes, A. V.; Abraham, S. N.; Hultgren, S. J. Proc. Natl. Acad. Sci. U.S.A. 1995, 92, 2081.
6. Johnson, J. R. Clin. Microbiol. Rev. 1991, 4, 80.
7. Min, G. W.; Stolz, M.; Zhou, G.; Liang, F. X.; Sebbel, P.; Stoffler, D.; Glockshuber, R.; Sun, T. T.; Aebi, U.; Kong, X. P. J. Mol. Biol. 2002, 317, 697.
8. Zhou, G.; Mo, W. J.; Sebbel, P.; Min, G. W.; Neubert, T. A.; Glockshuber, R.; Wu, X. R.; Sun, T. T.; Kong, X. P. J. Cell. Sci. 2001, 114, 4095.
9. Mulvey, M. A.; Lopez-Boado, Y. S.; Wilson, C. L.; Roth, R.; Parks, W. C.; Heuser, J.; Hultgren, S. J. Science 1998, 282, 1494.
10. Martinez, J. J.; Mulvey, M. A.; Schilling, J. D.; Pinkner, J. S.; Hultgren, S. J. EMBO. J. 2000, 19, 2803.
11. Hung, C. S.; Bouckaert, J.; Hung, D.; Pinkner, J. S.; Widberg, C.; DeFusco, A.; Auguste, C. G.; Strouse, R.; Langermann, S.; Waksman, G.; Hultgren, S. J. Mol. Microbiol. 2002, 44, 903.
12. Anderson, G. G.; Palermo, J. J.; Schilling, J. D.; Roth, R.; Heuser, J.; Hultgren, S. J. Science 2003, 301, 105.
13. Mulvey, M. A.; Schilling, J. D.; Hultgren, S. J. Infect. Immun. 2001, 69, 4572.
14. Mysorekar, I. U.; Hultgren, S. J. Proc. Natl. Acad. Sci. U.S.A. 2006, 103, 14170.
15. Li, Y.; Hindi, K.; Watts, K. M.; Taylor, J. B.; Zhang, K.; Li, Z. C.; Hunstad, D. A.; Cannon, C. L.; Youngs, W. J.; Wooley, K. L. Chem. Commun. 2010, 46, 121.
16. Lin, L. Y.; Lee, N. S.; Zhu, J.; Nyström, A. M.; Pochan, D. J.; Dorshow, R. B.; Wooley, K. L. J. Controlled Release 2011, 152, 37.
17. Nyström, A. M.; Wooley, K. L. Acc. Chem. Res. 2011, 44, 969.
18. Xu, J. Q.; Sun, G. R.; Rossin, R. H., A.; Li, Z. C.; Fukukawa, K.; Messmore, B. W.; Moore, D. A.; Welch, M. J.; Hawker, C. J.; Wooley, K. L. Macromolecules 2007, 40, 2971.
19. Champion, J. A.; Mitragotri, S. Proc. Natl. Acad. Sci. U.S.A. 2006, 103, 4930.
20. Sharma, G.; Valenta, D. T.; Altman, Y.; Harvey, S.; Xie, H.; Mitragotri, S.; Smith, J. W. J. Controlled Release 2010, 147, 408.
21. Hung, C. S.; Dodson, K. W.; Hultgren, S. J. Nat. Protoc. 2009, 4, 1230.
22. Aymonier, C.; Schlotterbeck, U.; Antonietti, L.; Zacharias, P.; Thomann, R.; Tiller, J. C.; Mecking, S. Chem. Commun. 2002, 24, 3018.
23. Russell, A. D.; Hugo, W. B. Med. Chem. 1994, 31, 351.
24. Sambhy, V.; MacBride, M. M.; Peterson, B. R.; Sen, A. J. Am. Chem. Soc. 2006, 128, 9798.
25. Silver, S. FEMS. Microbiol. Rev. 2003, 27, 341.
26. Spadaro, J. A.; Berger, T. J.; Barranco, S. D.; Chapin, S. E.; Becker, R. O. Microb. Agents Chemother. 1974, 6, 637.
27. Youngs, W. J.; Tessier, C. A.; Garrison, J. C.; Quezada, C. A.; Melaiye, A.; Durmus, S.; Panzner, M. J.; Kascatan-Nebioglu, A. In Medicinal Inorganic Chemistry; Sessler, J., Lippards, S., Eds.; Oxford University Press: New York, 2005; Vol. 903, p 414.
28. Langermann, S.; Mollby, R.; Burlein, J. E.; Palaszynski, S. R.; Auguste, C. G.; DeFusco, A.; Strouse, R.; Schenerman, M. A.; Hultgren, S. J.; Pinkner, J. S.; Winberg, J.; Guldevall, L.; Soderhall, M.; Ishikawa, K.; Normark, S.; Koenig, S. J. Infect. Dis. 2000, 181, 774.
29. Langermann, S.; Palaszynski, S.; Barnhart, M.; Auguste, G.; Pinkner, J. S.; Burlein, J.; Barren, P.; Koenig, S.; Leath, S.; Jones, C. H.; Hultgren, S. J. Science 1997, 276, 607.
30. Tchesnokova, V.; Aprikian, P.; Kisiela, D.; Gowey, S.; Korotkova, N.; Thomas, W.; Sokurenko, E. Infect. Immun. 2011, 79, 3895.