Synthesis of a novel series of L-isoserine derivatives as aminopeptidase N inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 27, Issue 2, 2012, Pages 302-310

  Yang, Kanghui ^a   Fen, Jinghong ^a   Fang, Hao ^a   Zhang, Lei ^a   Gong, Jianzhi ^a   Xu, Wenfang ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Aminopeptidase N inhibitor; L isoserine; Synthesis

Indexed keywords

(S) 3 (TERTBUTOXYCARBONYLAMINO) 2 HYDROXYPROPANOIC ACID; ANTINEOPLASTIC AGENT; BESTATIN; ENZYME INHIBITOR; ISOSERINE; ISOSERINE DERIVATIVE; ISOSERYLLEUCINE BENZYLESTER HYDROCHLORIDE; ISOSERYLLEUCINE HYDROCHLORIDE; ISOSERYLLEUCINE METHYLESTER HYDROCHLORIDE; ISOSERYLLEUCYLPHENYLALANINE BENZYLESTER HYDROCHLORIDE; ISOSERYLLEUCYLPHENYLALANINE HYDROCHLORIDE; ISOSERYLLEUCYLPHENYLALANINE METHYLESTER HYDROCHLORIDE; ISOSERYLPHENYLALANINE BENZYLESTER HYDROCHLORIDE; ISOSERYLPHENYLALANYLLEUCINE BENZYLESTER HYDROCHLORIDE; ISOSERYLPHENYLALANYLLEUCINE HYDROCHLORIDE; ISOSERYLPHENYLALANYLLEUCINE METHYLESTER HYDROCHLORIDE; LEUCYLPHENYLALANINE BENZYLESTER HYDROCHLORIDE; MICROSOMAL AMINOPEPTIDASE; PHENYLALANYLLEUCINE BENZYLESTER HYDROCHLORIDE; PHENYLALANYLLEUCINE METHYLESTER HYDROCHLORIDE; UNCLASSIFIED DRUG;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL VIABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

ANTIGENS, CD13; ANTINEOPLASTIC AGENTS; CELL PROLIFERATION; HUMANS; LEUCINE; MODELS, MOLECULAR; NEOPLASMS; PROTEASE INHIBITORS; SERINE; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 84863230183     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.3109/14756361003698147     Document Type: Article

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