Inhibition of adrenergic human prostate smooth muscle contraction by the inhibitors of c-Jun N-terminal kinase, SP600125 and BI-78D3

British Journal of Pharmacology

Volumn 166, Issue 6, 2012, Pages 1926-1935

  Strittmatter, F ^a   Walther, S ^a   Gratzke, C ^a   Gottinger J ^a   Beckmann, C ^a   Roosen, A ^a   Schlenker, B ^a   Hedlund, P ^b   Andersson, K E ^c   Stief, C G ^a   Hennenberg, M ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

^c WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

1 adrenoceptor; Benign prostate hyperplasia; JNK; Lower urinary tract symptoms; Mitogen activated protein kinase; Smooth muscle contraction

Indexed keywords

4 (2,3 DIHYDRO 1,4 BENZODIOXIN 6 YL) 2,4 DIHYDRO 5 [(5 NITRO 2 THIAZOLYL)THIOL] 3H 1,2,4 TRIAZOL 3 ONE; ALPHA 1 ADRENERGIC RECEPTOR; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BI 78D3; NORADRENALIN; PHENYLEPHRINE; PROTEIN C JUN; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG;

ADRENERGIC ACTIVITY; AGED; ALPHA ADRENERGIC STIMULATION; ANTIBODY SPECIFICITY; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ELECTROSTIMULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME MECHANISM; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INHIBITION KINETICS; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE FIBER; WESTERN BLOTTING;

AGED; ANTHRACENES; DIOXANES; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH; PROSTATE; PROTEIN KINASE INHIBITORS; RECEPTORS, ADRENERGIC, ALPHA-1; THIAZOLES;

EID: 84863214843     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2012.01919.x     Document Type: Article

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