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Volumn 20, Issue 14, 2012, Pages 4390-4396

Modified tetrahalogenated benzimidazoles with CK2 inhibitory activity are active against human prostate cancer cells LNCaP in vitro

(5) Schneider, Carolin C a Kartarius, Sabine a Montenarh, Mathias a Orzeszko, Andrzej b,c Kazimierczuk, Zygmunt b

a SAARLAND UNIVERSITY (Germany)

b WARSAW UNIVERSITY OF LIFE SCIENCES (Poland)

c MILITARY UNIVERSITY OF TECHNOLOGY (Poland)

Author keywords

Anticancer activity; CK2; Human prostate cancer cell line LCNaP; Kinase inhibitors; Tetrahalogenobenzimidazoles

Indexed keywords

2 BROMO 4,5,6,7 TETRAIODO 1 METHYL 1H BENZIMIDAZOLE; 4,5,6,7 TETRABROMOBENZIMIDAZOLE; 4,5,6,7 TETRAIODOBENZIMIDAZOLE; ANTINEOPLASTIC AGENT; CASEIN KINASE II; N (4,5,6,7 TETRABROMO 1H BENZIMIDAZOL 2 YL) BUTANE 1,2 DIAMINE; N (4,5,6,7 TETRABROMO 1H BENZIMIDAZOL 2 YL) ETHANE 1,2 DIAMINE; N (4,5,6,7 TETRABROMO 1H BENZIMIDAZOL 2 YL) PROPANE 1,2 DIAMINE; N (4,5,6,7 TETRABROMO METHYL 1H BENZIMIDAZOL 2 YL) ETHANE 1,2 DIAMINE; N (4,5,6,7 TETRAIODO 1 METHYL 1H BENZIMIDAZOL 2 YL) ETHANE 1,2 DIAMINE; N (4,5,67 TETRAIODO 1H BENZIMIDAZOLE 2 YL) ETHANE 1,2 DIAMINE; N N DIMETHYL N (4,5,6,7 TETRABROMO 1H BENZIMIDAZOL 2 YL) ETHANE 1,2 DIAMINE; N,N DIMETHYL N (4,5,6,7 TETRAIDO 1H BENZIMIDAZOL 2 YL) ETANE 1,2 DIAMINE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CELL CYCLE ARREST; CELL SURVIVAL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; HUMAN; HUMAN CELL; PROSTATE CANCER;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BENZIMIDAZOLES; CASEIN KINASE II; CELL LINE, TUMOR; HUMANS; MALE; PROSTATIC NEOPLASMS; PROTEIN KINASE INHIBITORS;

EID: 84863206953 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2012.05.038 Document Type: Article

Times cited : (18)

References (43)

1
- 0030976507
- L.K. Wilson, N. Dhillon, J. Thorner, and G.S. Martin J. Biol. Chem. 272 1997 12961
- (1997) J. Biol. Chem. , vol.272 , pp. 12961
- Wilson, L.K.¹ Dhillon, N.² Thorner, J.³ Martin, G.S.⁴

2
- 52149084777
- G. Vilk, J.E. Weber, J.P. Turowec, J.S. Duncan, C. Wu, D.R. Derksen, P. Zien, S. Sarno, A. Donella-Deana, G. Lajoie, L.A. Pinna, S.S.C. Li, and D.W. Litchfield Cell. Signal. 20 2008 1942
- (2008) Cell. Signal. , vol.20 , pp. 1942
- Vilk, G.¹ Weber, J.E.² Turowec, J.P.³ Duncan, J.S.⁴ Wu, C.⁵ Derksen, D.R.⁶ Zien, P.⁷ Sarno, S.⁸ Donella-Deana, A.⁹ Lajoie, G.¹⁰ Pinna, L.A.¹¹ Li, S.S.C.¹² Litchfield, D.W.¹³

3
- 0037334895
- F. Meggio, and L.A. Pinna FASEB J. 17 2003 349
- (2003) FASEB J. , vol.17 , pp. 349
- Meggio, F.¹ Pinna, L.A.²

4
- 75349084777
- M. Ruzzene, and L.A. Pinna Biochim. Biophys. Acta 1804 2010 499
- (2010) Biochim. Biophys. Acta , vol.1804 , pp. 499
- Ruzzene, M.¹ Pinna, L.A.²

5
- 77955734928
- Z. Trembley, G. Chen, J. Unger, B.T. Slaton, C. Kren, C. Van Waes, and K. Ahmed BioFactors 36 2010 187
- (2010) BioFactors , vol.36 , pp. 187
- Trembley, Z.¹ Chen, G.² Unger, J.³ Slaton, B.T.⁴ Kren, C.⁵ Van Waes, C.⁶ Ahmed, K.⁷

6
- 33847655629
- M. Laramas, D. Pasquier, O. Filhol, F. Ringeisen, J.L. Descotes, and C. Cochet Eur. J. Cancer 43 2007 928
- (2007) Eur. J. Cancer , vol.43 , pp. 928
- Laramas, M.¹ Pasquier, D.² Filhol, O.³ Ringeisen, F.⁴ Descotes, J.L.⁵ Cochet, C.⁶

7
- 33847361829
- J.S. Kim, J.I. Eom, J.W. Cheong, A.J. Choi, J.K. Lee, W.I. Yang, and Y.H. Min Clin. Cancer Res. 13 2007 1019
- (2007) Clin. Cancer Res. , vol.13 , pp. 1019
- Kim, J.S.¹ Eom, J.I.² Cheong, J.W.³ Choi, A.J.⁴ Lee, J.K.⁵ Yang, W.I.⁶ Min, Y.H.⁷

8
- 0032708113
- K. Niefind, M. Putter, B. Guerra, O.-G. Issinger, and D. Schomburg Nat. Struct. Biol. 6 1999 1100
- (1999) Nat. Struct. Biol. , vol.6 , pp. 1100
- Niefind, K.¹ Putter, M.² Guerra, B.³ Issinger, O.-G.⁴ Schomburg, D.⁵

9
- 14644402341
- C.W. Yde, I. Ermakova, O.-G. Issinger, and K. Niefind J. Mol. Biol. 347 2005 399
- (2005) J. Mol. Biol. , vol.347 , pp. 399
- Yde, C.W.¹ Ermakova, I.² Issinger, O.-G.³ Niefind, K.⁴

10
- 77950473958
- D. Huang, T. Zhou, K. Lafleur, and C. Nevado Bioinformatics 26 2010 198
- (2010) Bioinformatics , vol.26 , pp. 198
- Huang, D.¹ Zhou, T.² Lafleur, K.³ Nevado, C.⁴

11
- 35348947572
- R. Battistutta, M. Mazzorana, L. Cendron, A. Bortolato, S. Sarno, Z. Kazimierczuk, G. Zanotti, S. Moro, and L.A. Pinna ChemBioChem 8 2007 1804
- (2007) ChemBioChem , vol.8 , pp. 1804
- Battistutta, R.¹ Mazzorana, M.² Cendron, L.³ Bortolato, A.⁴ Sarno, S.⁵ Kazimierczuk, Z.⁶ Zanotti, G.⁷ Moro, S.⁸ Pinna, L.A.⁹

12
- 50649094477
- M. Mazzorana, L.A. Pinna, and R. Battistutta Mol. Cell. Biochem. 316 2008 57
- (2008) Mol. Cell. Biochem. , vol.316 , pp. 57
- Mazzorana, M.¹ Pinna, L.A.² Battistutta, R.³

13
- 9744244918
- M.A. Pagano, M. Andrzejewska, M. Ruzzene, S. Sarno, L. Cesaro, J. Bain, M. Elliott, F. Meggio, Z. Kazimierczuk, and L.A. Pinna J. Med. Chem. 47 2004 6239
- (2004) J. Med. Chem. , vol.47 , pp. 6239
- Pagano, M.A.¹ Andrzejewska, M.² Ruzzene, M.³ Sarno, S.⁴ Cesaro, L.⁵ Bain, J.⁶ Elliott, M.⁷ Meggio, F.⁸ Kazimierczuk, Z.⁹ Pinna, L.A.¹⁰

14
- 71749121257
- A. Gianoncelli, G. Cozza, A. Orzeszko, F. Meggio, Z. Kazimierczuk, and L.A. Pinna Bioorg. Med. Chem. 17 2009 7281
- (2009) Bioorg. Med. Chem. , vol.17 , pp. 7281
- Gianoncelli, A.¹ Cozza, G.² Orzeszko, A.³ Meggio, F.⁴ Kazimierczuk, Z.⁵ Pinna, L.A.⁶

15
- 0037716542
- P. Zień, M. Bretner, K. Zastapiło, R. Szyszka, and D. Shugar Biochem. Biophys. Res. Commun. 306 2003 129
- (2003) Biochem. Biophys. Res. Commun. , vol.306 , pp. 129
- Zień, P.¹ Bretner, M.² Zastapiło, K.³ Szyszka, R.⁴ Shugar, D.⁵

16
- 39749107915
- A. Chilin, R. Battistutta, A. Bortolato, G. Cozza, S. Zanatta, G. Poletto, M. Mazzorana, G. Zagotto, E. Uriarte, A. Guiotto, L.A. Pinna, F. Meggio, and S. Moro J. Med. Chem. 51 2008 752
- (2008) J. Med. Chem. , vol.51 , pp. 752
- Chilin, A.¹ Battistutta, R.² Bortolato, A.³ Cozza, G.⁴ Zanatta, S.⁵ Poletto, G.⁶ Mazzorana, M.⁷ Zagotto, G.⁸ Uriarte, E.⁹ Guiotto, A.¹⁰ Pinna, L.A.¹¹ Meggio, F.¹² Moro, S.¹³

17
- 38149041702
- Z.C. Perretta, P. Erickson, S. Margosiak, J. Lu, A. Averill, R. Almassy, and S. Chu Bioorg. Med. Chem. Lett. 18 2008 619
- (2008) Bioorg. Med. Chem. Lett. , vol.18 , pp. 619
- Perretta, Z.C.¹ Erickson, P.² Margosiak, S.³ Lu, J.⁴ Averill, A.⁵ Almassy, R.⁶ Chu, S.⁷

18
- 68249130300
- G. Cozza, M. Mazzorana, E. Papinutto, J. Bain, M. Elliott, G. Di Maira, A. Gianoncelli, M.A. Pagano, S. Sarno, M. Ruzzene, R. Battistutta, F. Meggio, S. Moro, G. Zagotto, and L.A. Pinna Biochem. J. 421 2009 387
- (2009) Biochem. J. , vol.421 , pp. 387
- Cozza, G.¹ Mazzorana, M.² Papinutto, E.³ Bain, J.⁴ Elliott, M.⁵ Di Maira, G.⁶ Gianoncelli, A.⁷ Pagano, M.A.⁸ Sarno, S.⁹ Ruzzene, M.¹⁰ Battistutta, R.¹¹ Meggio, F.¹² Moro, S.¹³ Zagotto, G.¹⁴ Pinna, L.A.¹⁵

19
- 33748163052
- F.A. Piazza, M. Ruzzene, C. Gurrieri, B. Montini, L. Bonanni, G. Chioetto, G. Di Maira, F. Barbon, A. Cabrelle, R. Zambello, F. Adami, L. Trentin, L.A. Pinna, and G. Semenzato Blood 108 2006 1698
- (2006) Blood , vol.108 , pp. 1698
- Piazza, F.A.¹ Ruzzene, M.² Gurrieri, C.³ Montini, B.⁴ Bonanni, L.⁵ Chioetto, G.⁶ Di Maira, G.⁷ Barbon, F.⁸ Cabrelle, A.⁹ Zambello, R.¹⁰ Adami, F.¹¹ Trentin, L.¹² Pinna, L.A.¹³ Semenzato, G.¹⁴

20
- 33847361829
- J.S. Kim, J.L. Eom, J.W. Cheong, A.J. Choi, J.K. Lee, W.I. Yang, and Y.H. Min Clin. Cancer Res. 13 2007 1019
- (2007) Clin. Cancer Res. , vol.13 , pp. 1019
- Kim, J.S.¹ Eom, J.L.² Cheong, J.W.³ Choi, A.J.⁴ Lee, J.K.⁵ Yang, W.I.⁶ Min, Y.H.⁷

21
- 38449100168
- R. Hamacher, D. Saur, R. Fritsch, M. Reichert, R.M. Schmid, and G. Schneider Oncol. Rep. 18 2007 695
- (2007) Oncol. Rep. , vol.18 , pp. 695
- Hamacher, R.¹ Saur, D.² Fritsch, R.³ Reichert, M.⁴ Schmid, R.M.⁵ Schneider, G.⁶

22
- 73449138209
- D. Zhu, J. Hensel, R. Hilgraf, M. Abbasian, O. Pornillos, G. Deyanat-Yazdi, X.H. Hua, and S. Cox Mol. Cell. Biochem. 333 2010 159
- (2010) Mol. Cell. Biochem. , vol.333 , pp. 159
- Zhu, D.¹ Hensel, J.² Hilgraf, R.³ Abbasian, M.⁴ Pornillos, O.⁵ Deyanat-Yazdi, G.⁶ Hua, X.H.⁷ Cox, S.⁸

23
- 34548668897
- C.W. Yde, T. Frogne, A.E. Lykkesfeldt, I. Fichtner, O.-G. Issinger, and J. Stenvang Cancer Lett. 256 2007 229
- (2007) Cancer Lett. , vol.256 , pp. 229
- Yde, C.W.¹ Frogne, T.² Lykkesfeldt, A.E.³ Fichtner, I.⁴ Issinger, O.-G.⁵ Stenvang, J.⁶

24
- 77953229921
- H. Lawnicka, M. Kowalewicz-Kulbat, P. Sicinska, Z. Kazimierczuk, P. Grieb, and H. Stepien Cell Tissue Res. 340 2010 371
- (2010) Cell Tissue Res. , vol.340 , pp. 371
- Lawnicka, H.¹ Kowalewicz-Kulbat, M.² Sicinska, P.³ Kazimierczuk, Z.⁴ Grieb, P.⁵ Stepien, H.⁶

25
- 3843114402
- M.A. Pagano, F. Meggio, M. Ruzzene, M. Andrzejewska, Z. Kazimierczuk, and L.A. Pinna Biochem. Biophys. Res. Commun. 321 2004 1040
- (2004) Biochem. Biophys. Res. Commun. , vol.321 , pp. 1040
- Pagano, M.A.¹ Meggio, F.² Ruzzene, M.³ Andrzejewska, M.⁴ Kazimierczuk, Z.⁵ Pinna, L.A.⁶

26
- 50649107702
- R. Prudent, V. Moucadel, M. Lopez-Ramos, S. Aci, B. Laudet, L. Mouawad, C. Barette, J. Einhorn, C. Einhorn, J.N. Denis, G. Bisson, F. Schmidt, S. Roy, L. Lafanechere, J.C. Florent, and C. Cochet Mol. Cell. Biochem. 316 2008 71
- (2008) Mol. Cell. Biochem. , vol.316 , pp. 71
- Prudent, R.¹ Moucadel, V.² Lopez-Ramos, M.³ Aci, S.⁴ Laudet, B.⁵ Mouawad, L.⁶ Barette, C.⁷ Einhorn, J.⁸ Einhorn, C.⁹ Denis, J.N.¹⁰ Bisson, G.¹¹ Schmidt, F.¹² Roy, S.¹³ Lafanechere, L.¹⁴ Florent, J.C.¹⁵ Cochet, C.¹⁶

27
- 78650321320
- A. Siddiqui-Jain, D. Drygin, N. Streiner, P. Chua, F. Pierre, S.E. O'Brien, J. Bliesath, M. Omori, N. Huser, C. Ho, C. Proffitt, M.K. Schwaebe, D.M. Ryckman, W.G. Rice, and K. Anderes Cancer Res. 70 2010 10288
- (2010) Cancer Res. , vol.70 , pp. 10288
- Siddiqui-Jain, A.¹ Drygin, D.² Streiner, N.³ Chua, P.⁴ Pierre, F.⁵ O'Brien, S.E.⁶ Bliesath, J.⁷ Omori, M.⁸ Huser, N.⁹ Ho, C.¹⁰ Proffitt, C.¹¹ Schwaebe, M.K.¹² Ryckman, D.M.¹³ Rice, W.G.¹⁴ Anderes, K.¹⁵

28
- 50649090911
- J.A. Kramerov, M. Saghizadeh, S. Caballero, L.C. Shaw, S. Li Calzi, M. Bretner, M. Montenarh, L.A. Pinna, M. Grant, and A. Ljubimov Mol. Cell. Biochem. 316 2008 177
- (2008) Mol. Cell. Biochem. , vol.316 , pp. 177
- Kramerov, J.A.¹ Saghizadeh, M.² Caballero, S.³ Shaw, L.C.⁴ Li Calzi, S.⁵ Bretner, M.⁶ Montenarh, M.⁷ Pinna, L.A.⁸ Grant, M.⁹ Ljubimov, A.¹⁰

29
- 79960013995
- G. Sass, N. Klinger, H. Sirma, S. Hashemolhosseini, C. Hellerbrand, D. Neureiter, H. Wege, M. Ocker, and G. Tiegs Int. J. Oncol. 39 2011 433
- (2011) Int. J. Oncol. , vol.39 , pp. 433
- Sass, G.¹ Klinger, N.² Sirma, H.³ Hashemolhosseini, S.⁴ Hellerbrand, C.⁵ Neureiter, D.⁶ Wege, H.⁷ Ocker, M.⁸ Tiegs, G.⁹

30
- 0025060131
- F. Meggio, D. Shugar, and L.A. Pinna Eur. J. Biochem. 187 1990 89
- (1990) Eur. J. Biochem. , vol.187 , pp. 89
- Meggio, F.¹ Shugar, D.² Pinna, L.A.³

31
- 0035805108
- S. Sarno, H. Reddy, F. Meggio, M. Ruzzene, S.P. Davies, A. Donella-Deana, D. Shugar, and L.A. Pinna FEBS Lett. 496 2001 44
- (2001) FEBS Lett. , vol.496 , pp. 44
- Sarno, S.¹ Reddy, H.² Meggio, F.³ Ruzzene, M.⁴ Davies, S.P.⁵ Donella-Deana, A.⁶ Shugar, D.⁷ Pinna, L.A.⁸

32
- 63449124343
- M.A. Pagano, J. Bain, Z. Kazimierczuk, S. Sarno, M. Ruzzene, G. Di Maira, M. Elliott, A. Orzeszko, G. Cozza, F. Meggio, and L.A. Pinna Biochem. J. 415 2008 353
- (2008) Biochem. J. , vol.415 , pp. 353
- Pagano, M.A.¹ Bain, J.² Kazimierczuk, Z.³ Sarno, S.⁴ Ruzzene, M.⁵ Di Maira, G.⁶ Elliott, M.⁷ Orzeszko, A.⁸ Cozza, G.⁹ Meggio, F.¹⁰ Pinna, L.A.¹¹

33
- 84855808664
- M. Janeczko, A. Orzeszko, Z. Kazimierczuk, R. Szyszka, and A. Baier Eur. J. Med. Chem. 47 2012 345
- (2012) Eur. J. Med. Chem. , vol.47 , pp. 345
- Janeczko, M.¹ Orzeszko, A.² Kazimierczuk, Z.³ Szyszka, R.⁴ Baier, A.⁵

34
- 79952232216
- A. Jemal, F. Bray, M.M. Center, J. Ferlay, E. Ward, and D. Forman CA Cancer J. Clin. 61 2011 69
- (2011) CA Cancer J. Clin. , vol.61 , pp. 69
- Jemal, A.¹ Bray, F.² Center, M.M.³ Ferlay, J.⁴ Ward, E.⁵ Forman, D.⁶

35
- 30044447244
- S. McKenzie, and N. Kyprianou J. Cell. Biochem. 97 2006 18
- (2006) J. Cell. Biochem. , vol.97 , pp. 18
- McKenzie, S.¹ Kyprianou, N.²

36
- 84855226016
- J.P. Turowec, J.S. Duncan, G.B. Gloor, and D.W. Litchfield Mol. Cell. Biochem. 356 2011 159
- (2011) Mol. Cell. Biochem. , vol.356 , pp. 159
- Turowec, J.P.¹ Duncan, J.S.² Gloor, G.B.³ Litchfield, D.W.⁴

37
- 79960392817
- N.A. St-Denis, M.L. Bailey, E.L. Parker, G. Vilk, and D.W. Litchfield J. Cell Sci. 124 2011 2341
- (2011) J. Cell Sci. , vol.124 , pp. 2341
- St-Denis, N.A.¹ Bailey, M.L.² Parker, E.L.³ Vilk, G.⁴ Litchfield, D.W.⁵

38
- 73449102163
- C.C. Schneider, A. Hessenauer, M. Montenarh, and C. Götz Prostate 70 2010 126
- (2010) Prostate , vol.70 , pp. 126
- Schneider, C.C.¹ Hessenauer, A.² Montenarh, M.³ Götz, C.⁴

39
- 67649947497
- C.C. Schneider, A. Hessenauer, C. Götz, and M. Montenarh Oncol. Rep. 21 2009 1593
- (2009) Oncol. Rep. , vol.21 , pp. 1593
- Schneider, C.C.¹ Hessenauer, A.² Götz, C.³ Montenarh, M.⁴

40
- 33744819434
- K.A. Ahmad, G. Wang, and K. Ahmed Mol. Cancer Res. 4 2006 331
- (2006) Mol. Cancer Res. , vol.4 , pp. 331
- Ahmad, K.A.¹ Wang, G.² Ahmed, K.³

41
- 69149095891
- I.M. Hanif, K.A. Ahmad, K. Ahmed, and S. Pervaiz Ann. N.Y. Acad. Sci. 1171 2009 591
- (2009) Ann. N.Y. Acad. Sci. , vol.1171 , pp. 591
- Hanif, I.M.¹ Ahmad, K.A.² Ahmed, K.³ Pervaiz, S.⁴

42
- 0014949207
- U.K. Laemmli Nature 227 1970 680
- (1970) Nature , vol.227 , pp. 680
- Laemmli, U.K.¹

43
- 0042591222
- M. Andrzejewska, M.A. Pagano, F. Meggio, A.M. Brunati, and Z. Kazimierczuk Bioorg. Med. Chem. 11 2003 3997
- (2003) Bioorg. Med. Chem. , vol.11 , pp. 3997
- Andrzejewska, M.¹ Pagano, M.A.² Meggio, F.³ Brunati, A.M.⁴ Kazimierczuk, Z.⁵

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