SP-1 regulation of MMP-9 expression requires Ser586in the PEST domain

Biochemical Journal

Volumn 445, Issue 2, 2012, Pages 229-236

  Murthy, Shubha ^a   Ryan, Alan J ^a   Carter, A Brent ^a,b,c  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Extracellular signal regulated kinase (ERK); Macrophage; Matrix metalloproteinase 9 (MMP 9); Pulmonary fibrosis; Rac1; Specificity protein 1 (SP 1)

Indexed keywords

ASBESTOS; COMPLEMENTARY DNA; GELATINASE B; MITOGEN ACTIVATED PROTEIN KINASE; PROLYLGLUTAMINYLSERYLTHREONINE; RAC1 PROTEIN; RECOMBINANT PROTEIN; RNA; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA BINDING; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBEROPTIC BRONCHOSCOPY; GENETIC TRANSCRIPTION; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; LUNG ALVEOLUS MACROPHAGE; LUNG FIBROSIS; LUNG LAVAGE; MOUSE; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; REAL TIME POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION;

ADOLESCENT; ADULT; ANIMALS; BLOTTING, WESTERN; CHROMATIN IMMUNOPRECIPITATION; ELECTROPHORETIC MOBILITY SHIFT ASSAY; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MACROPHAGES, ALVEOLAR; MATRIX METALLOPROTEINASE 9; MICE; MICE, KNOCKOUT; MIDDLE AGED; MUTATION; NEUROPEPTIDES; PROTEIN STRUCTURE, TERTIARY; RAC GTP-BINDING PROTEINS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SERINE; SIGNAL TRANSDUCTION; SP1 TRANSCRIPTION FACTOR; YOUNG ADULT;

EID: 84863192311     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20120053     Document Type: Article

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