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Volumn 27, Issue 2, 2012, Pages 556-565

1H NMR spectroscopy analysis of metabolites in the kidneys provides new insight into pathophysiological mechanisms: Applications for treatment with Cordyceps sinensis

Author keywords

5 6 nephrectomy; 1H NMR spectroscopy analysis; Cordyceps sinensis; metabonomics; pathophysiology

Indexed keywords

ADENOSINE; ALLANTOIN; ASPARTIC ACID; BETAINE; CARNITINE; CHOLINE; CREATININE; FORMIC ACID; FUMARIC ACID; GLUTAMIC ACID; GLYCINE; HERBACEOUS AGENT; INOSITOL; ISOLEUCINE; LACTIC ACID; LEUCINE; MALIC ACID; METHIONINE; NICOTINAMIDE; PHOSPHOYLCHOLINE; PROLINE; SUCCINIC ACID; TAURINE; UNCLASSIFIED DRUG; VALINE; BRANCHED CHAIN AMINO ACID;

EID: 84863183008     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfr368     Document Type: Article
Times cited : (31)

References (55)
  • 1
    • 77954869012 scopus 로고    scopus 로고
    • The conundrum of chronic kidney disease classification and end-stage renal risk prediction in the elderly-what is the right approach?
    • Hallan SI, Orth SR. The conundrum of chronic kidney disease classification and end-stage renal risk prediction in the elderly-what is the right approach? Nephron Clin Pract 2010; 116: c307-c316
    • (2010) Nephron Clin Pract , vol.116
    • Hallan, S.I.1    Orth, S.R.2
  • 2
    • 44349167598 scopus 로고    scopus 로고
    • Strategies and methods of integrated traditional Chinese and Western medicine in preventing and treating chronic kidney disease
    • Wei LB, Huang LW. Strategies and methods of integrated traditional Chinese and Western medicine in preventing and treating chronic kidney disease. Zhong Xi Yi Jie He Xue Bao 2008; 6: 449-453
    • (2008) Zhong Xi Yi Jie He Xue Bao , vol.6 , pp. 449-453
    • Wei, L.B.1    Huang, L.W.2
  • 3
    • 42049101429 scopus 로고    scopus 로고
    • Cordyceps: A traditional Chinese medicine and another fungal therapeutic biofactory?
    • Paterson RR. Cordyceps: a traditional Chinese medicine and another fungal therapeutic biofactory? Phytochemistry 2008; 69: 1469-1495
    • (2008) Phytochemistry , vol.69 , pp. 1469-1495
    • Paterson, R.R.1
  • 4
    • 33646049054 scopus 로고    scopus 로고
    • Morphological and genetic characterization of a cultivated Cordyceps sinensis fungus and its polysaccharide component possessing antioxidant property in H22 tumor-bearing mice
    • Chen J, Zhang W, Lu T et al. Morphological and genetic characterization of a cultivated Cordyceps sinensis fungus and its polysaccharide component possessing antioxidant property in H22 tumor-bearing mice. Life Sci 2006; 78: 2742-2748
    • (2006) Life Sci , vol.78 , pp. 2742-2748
    • Chen, J.1    Zhang, W.2    Lu, T.3
  • 5
    • 0036876595 scopus 로고    scopus 로고
    • Immunomodulatory functions of extracts from the Chinese medicinal fungus Cordyceps cicadae
    • Weng SC, Chou CJ, Lin LC et al. Immunomodulatory functions of extracts from the Chinese medicinal fungus Cordyceps cicadae. J Ethnopharmacol 2002; 83: 79-85
    • (2002) J Ethnopharmacol , vol.83 , pp. 79-85
    • Weng, S.C.1    Chou, C.J.2    Lin, L.C.3
  • 6
    • 85047686650 scopus 로고    scopus 로고
    • Cordyceps fungi: Natural products, pharmacological functions and developmental products
    • Zhou X, Gong Z, Su Y et al. Cordyceps fungi: natural products, pharmacological functions and developmental products. J Pharm Pharmacol 2009; 61: 279-291
    • (2009) J Pharm Pharmacol , vol.61 , pp. 279-291
    • Zhou, X.1    Gong, Z.2    Su, Y.3
  • 7
    • 21344460772 scopus 로고    scopus 로고
    • The nephroprotective effects of the herbal medicine preparation, WH301, on the chemical-induced acute and chronic renal failure in rats
    • Ngai HH, Sit WH, Wan JM. The nephroprotective effects of the herbal medicine preparation, WH301, on the chemical-induced acute and chronic renal failure in rats. Am J Chin Med 2005; 33: 491-500
    • (2005) Am J Chin Med , vol.33 , pp. 491-500
    • Ngai, H.H.1    Sit, W.H.2    Wan, J.M.3
  • 8
    • 77954217924 scopus 로고    scopus 로고
    • Protection of chronic renal failure by a polysaccharide from Cordyceps sinensis
    • Wang Y, Yin HP, Lv XB et al. Protection of chronic renal failure by a polysaccharide from Cordyceps sinensis. Fitoterapia 2010; 81: 397-402
    • (2010) Fitoterapia , vol.81 , pp. 397-402
    • Wang, Y.1    Yin, H.P.2    Lv, X.B.3
  • 9
    • 33645842478 scopus 로고    scopus 로고
    • Herbs or natural substances as complementary therapies for chronic kidney disease: Ideas for future studies
    • Wojcikowski K, Johnson DW, Gobe G. Herbs or natural substances as complementary therapies for chronic kidney disease: ideas for future studies. J Lab Clin Med 2006; 147: 160-166
    • (2006) J Lab Clin Med , vol.147 , pp. 160-166
    • Wojcikowski, K.1    Johnson, D.W.2    Gobe, G.3
  • 10
    • 0028797723 scopus 로고
    • Amelioration of cyclosporin nephrotoxicity by Cordyceps sinensis in kidney-transplanted recipients
    • Xu F, Huang JB, Jiang L et al. Amelioration of cyclosporin nephrotoxicity by Cordyceps sinensis in kidney-transplanted recipients. Nephrol Dial Transplant 1995; 10: 142-143
    • (1995) Nephrol Dial Transplant , vol.10 , pp. 142-143
    • Xu, F.1    Huang, J.B.2    Jiang, L.3
  • 11
    • 0027622839 scopus 로고
    • Cordyceps sinensis in protection of the kidney from cyclosporine A nephrotoxicity
    • 447
    • Zhao X, Li L. [Cordyceps sinensis in protection of the kidney from cyclosporine A nephrotoxicity]. Zhonghua Yi Xue Za Zhi 1993; 73: 410-412, . 447
    • (1993) Zhonghua Yi Xue Za Zhi , vol.73 , pp. 410-412
    • Zhao, X.1    Li, L.2
  • 12
    • 74049085012 scopus 로고    scopus 로고
    • Structural determination and antioxidant activity of a polysaccharide from the fruiting bodies of cultured Cordyceps sinensis
    • Wang Y, Wang M, Ling Y et al. Structural determination and antioxidant activity of a polysaccharide from the fruiting bodies of cultured Cordyceps sinensis. Am J Chin Med 2009; 37: 977-989
    • (2009) Am J Chin Med , vol.37 , pp. 977-989
    • Wang, Y.1    Wang, M.2    Ling, Y.3
  • 13
    • 0034634448 scopus 로고    scopus 로고
    • An NMR-based metabonomic approach to investigate the biochemical consequences of genetic strain differences: Application to the C57BL10J and Alpk:ApfCD mouse
    • Gavaghan CL, Holmes E, Lenz E et al. An NMR-based metabonomic approach to investigate the biochemical consequences of genetic strain differences: application to the C57BL10J and Alpk:ApfCD mouse. FEBS Lett 2000; 484: 169-174
    • (2000) FEBS Lett , vol.484 , pp. 169-174
    • Gavaghan, C.L.1    Holmes, E.2    Lenz, E.3
  • 14
    • 77950658599 scopus 로고    scopus 로고
    • Metabolomic analysis identifies inflammatory and noninflammatory metabolic effects of genetic modification in a mouse model of Crohn's disease
    • Lin HM, Barnett MP, Roy NC et al. Metabolomic analysis identifies inflammatory and noninflammatory metabolic effects of genetic modification in a mouse model of Crohn's disease. J Proteome Res 2010; 9: 1965-1975
    • (2010) J Proteome Res , vol.9 , pp. 1965-1975
    • Lin, H.M.1    Barnett, M.P.2    Roy, N.C.3
  • 15
    • 39149126959 scopus 로고    scopus 로고
    • 1H NMR metabonomics approach to the disease continuum of diabetic complications and premature death
    • Makinen VP, Soininen P, Forsblom C et al. 1H NMR metabonomics approach to the disease continuum of diabetic complications and premature death. Mol Syst Biol 2008; 4: 167
    • (2008) Mol Syst Biol , vol.4 , pp. 167
    • Makinen, V.P.1    Soininen, P.2    Forsblom, C.3
  • 16
    • 49049113111 scopus 로고    scopus 로고
    • Urinary metabolic profiles of inflammatory bowel disease in interleukin-10 gene-deficient mice
    • Murdoch TB, Fu H, MacFarlane S et al. Urinary metabolic profiles of inflammatory bowel disease in interleukin-10 gene-deficient mice. Anal Chem 2008; 80: 5524-5531
    • (2008) Anal Chem , vol.80 , pp. 5524-5531
    • Murdoch, T.B.1    Fu, H.2    MacFarlane, S.3
  • 17
    • 73649083369 scopus 로고    scopus 로고
    • NMR-based metabolic profiling identifies biomarkers of liver regeneration following partial hepatectomy in the rat
    • Bollard ME, Contel NR, Ebbels TM et al. NMR-based metabolic profiling identifies biomarkers of liver regeneration following partial hepatectomy in the rat. J Proteome Res 2010; 9: 59-69
    • (2010) J Proteome Res , vol.9 , pp. 59-69
    • Bollard, M.E.1    Contel, N.R.2    Ebbels, T.M.3
  • 18
    • 73949102432 scopus 로고    scopus 로고
    • 1H NMR spectroscopic study of blood serum for the assessment of liver function in liver transplant patients
    • Tripathi P, Bala L, Saxena R et al. 1H NMR spectroscopic study of blood serum for the assessment of liver function in liver transplant patients. J Gastrointestin Liver Dis 2009; 18: 329-336
    • (2009) J Gastrointestin Liver Dis , vol.18 , pp. 329-336
    • Tripathi, P.1    Bala, L.2    Saxena, R.3
  • 19
    • 71549117909 scopus 로고    scopus 로고
    • Pneumococcal pneumonia: Potential for diagnosis through a urinary metabolic profile
    • Slupsky CM, Rankin KN, Fu H et al. Pneumococcal pneumonia: potential for diagnosis through a urinary metabolic profile. J Proteome Res 2009; 8: 5550-5558
    • (2009) J Proteome Res , vol.8 , pp. 5550-5558
    • Slupsky, C.M.1    Rankin, K.N.2    Fu, H.3
  • 20
    • 77949417518 scopus 로고    scopus 로고
    • Metabolomics approaches for discovering biomarkers of drug-induced hepatotoxicity and nephrotoxicity
    • Beger RD, Sun J, Schnackenberg LK. Metabolomics approaches for discovering biomarkers of drug-induced hepatotoxicity and nephrotoxicity. Toxicol Appl Pharmacol 2010; 243: 154-166
    • (2010) Toxicol Appl Pharmacol , vol.243 , pp. 154-166
    • Beger, R.D.1    Sun, J.2    Schnackenberg, L.K.3
  • 22
    • 60549109881 scopus 로고    scopus 로고
    • Metabonomic analysis identifies molecular changes associated with the pathophysiology and drug treatment of bipolar disorder
    • Lan MJ, McLoughlin GA, Griffin JL et al. Metabonomic analysis identifies molecular changes associated with the pathophysiology and drug treatment of bipolar disorder. Mol Psychiatry 2009; 14: 269-279
    • (2009) Mol Psychiatry , vol.14 , pp. 269-279
    • Lan, M.J.1    McLoughlin, G.A.2    Griffin, J.L.3
  • 23
    • 76149113262 scopus 로고    scopus 로고
    • Metabonomics in ulcerative colitis: Diagnostics, biomarker identification, and insight into the pathophysiology
    • Bjerrum JT, Nielsen OH, Hao F et al. Metabonomics in ulcerative colitis: diagnostics, biomarker identification, and insight into the pathophysiology. J Proteome Res 2010; 9: 954-962
    • (2010) J Proteome Res , vol.9 , pp. 954-962
    • Bjerrum, J.T.1    Nielsen, O.H.2    Hao, F.3
  • 24
    • 52149124125 scopus 로고    scopus 로고
    • Effect of a traditional Chinese medicine preparation Xindi soft capsule on rat model of acute blood stasis: A urinary metabonomics study based on liquid chromatography-mass spectrometry
    • Zhao X, Zhang Y, Meng X et al. Effect of a traditional Chinese medicine preparation Xindi soft capsule on rat model of acute blood stasis: a urinary metabonomics study based on liquid chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2008; 873: 151-158
    • (2008) J Chromatogr B Analyt Technol Biomed Life Sci , vol.873 , pp. 151-158
    • Zhao, X.1    Zhang, Y.2    Meng, X.3
  • 25
    • 77949336458 scopus 로고    scopus 로고
    • Effect of traditional Chinese medicine berberine on type 2 diabetes based on comprehensive metabonomics
    • Gu Y, Zhang Y, Shi X et al. Effect of traditional Chinese medicine berberine on type 2 diabetes based on comprehensive metabonomics. Talanta 2010; 81: 766-772
    • (2010) Talanta , vol.81 , pp. 766-772
    • Gu, Y.1    Zhang, Y.2    Shi, X.3
  • 26
    • 84863170301 scopus 로고    scopus 로고
    • Investigation of therapeutic mechanism of Weiweifang on experimental gastric ulcer in rats viewing from metabonomics
    • Peng SL, Liu XW, Zhang ZR. Investigation of therapeutic mechanism of Weiweifang on experimental gastric ulcer in rats viewing from metabonomics. Zhongguo Zhong Xi Yi Jie He Za Zhi 2010; 30: 1073-1077
    • (2010) Zhongguo Zhong Xi Yi Jie He Za Zhi , vol.30 , pp. 1073-1077
    • Peng, S.L.1    Liu, X.W.2    Zhang, Z.R.3
  • 27
    • 84863120278 scopus 로고    scopus 로고
    • Effect of er'zhi tiangui granule on metabonomics and level of Ca21 in follicle fluid in patients after in vitro fertilization and embryo transfer
    • Lian F, Zhao B, Lu XM. Effect of er'zhi tiangui granule on metabonomics and level of Ca21 in follicle fluid in patients after in vitro fertilization and embryo transfer. Zhongguo Zhong Xi Yi Jie He Za Zhi 2010; 30: 22-25
    • (2010) Zhongguo Zhong Xi Yi Jie He Za Zhi , vol.30 , pp. 22-25
    • Lian, F.1    Zhao, B.2    Lu, X.M.3
  • 28
    • 79955379847 scopus 로고    scopus 로고
    • Metabonomic study of Chinese medicine Shuanglong Formula as an effective treatment for myocardial infarction in rats
    • Liang X, Chen X, Liang Q et al. Metabonomic study of Chinese medicine Shuanglong Formula as an effective treatment for myocardial infarction in rats. J Proteome Res 2011; 2: 790-799
    • (2011) J Proteome Res , vol.2 , pp. 790-799
    • Liang, X.1    Chen, X.2    Liang, Q.3
  • 29
    • 0030909314 scopus 로고    scopus 로고
    • Transforming growth factor beta 1 and renal injury following subtotal nephrectomy in the rat: Role of the renin-angiotensin system
    • Wu LL, Cox A, Roe CJ et al. Transforming growth factor beta 1 and renal injury following subtotal nephrectomy in the rat: role of the renin-angiotensin system. Kidney Int 1997; 51: 1553-1567
    • (1997) Kidney Int , vol.51 , pp. 1553-1567
    • Wu, L.L.1    Cox, A.2    Roe, C.J.3
  • 30
    • 39149126712 scopus 로고    scopus 로고
    • Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts
    • Beckonert O, Keun HC, Ebbels TM et al. Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts. Nat Protoc 2007; 2: 2692-2703
    • (2007) Nat Protoc , vol.2 , pp. 2692-2703
    • Beckonert, O.1    Keun, H.C.2    Ebbels, T.M.3
  • 31
    • 34948910696 scopus 로고    scopus 로고
    • An inflammatory arthritisassociated metabolite biomarker pattern revealed by 1H NMR spectroscopy
    • Weljie AM, Dowlatabadi R, Miller BJ et al. An inflammatory arthritisassociated metabolite biomarker pattern revealed by 1H NMR spectroscopy. J Proteome Res 2007; 6: 3456-3464
    • (2007) J Proteome Res , vol.6 , pp. 3456-3464
    • Weljie, A.M.1    Dowlatabadi, R.2    Miller, B.J.3
  • 32
    • 78449285472 scopus 로고    scopus 로고
    • Early detection of recurrent breast cancer using metabolite profiling
    • Asiago VM, Alvarado LZ, Shanaiah N et al. Early detection of recurrent breast cancer using metabolite profiling. Cancer Res 2010; 70: 8309-8318
    • (2010) Cancer Res , vol.70 , pp. 8309-8318
    • Asiago, V.M.1    Alvarado, L.Z.2    Shanaiah, N.3
  • 33
    • 71549122282 scopus 로고    scopus 로고
    • Systemic metabolic changes of traumatic critically ill patients revealed by an NMR-based metabonomic approach
    • Mao H, Wang H, Wang B et al. Systemic metabolic changes of traumatic critically ill patients revealed by an NMR-based metabonomic approach. J Proteome Res 2009; 8: 5423-5430
    • (2009) J Proteome Res , vol.8 , pp. 5423-5430
    • Mao, H.1    Wang, H.2    Wang, B.3
  • 34
    • 12244293657 scopus 로고    scopus 로고
    • Evaluation of the orthogonal projection on latent structure model limitations caused by chemical shift variability and improved visualization of biomarker changes in 1H NMR spectroscopic metabonomic studies
    • Cloarec O, Dumas ME, Trygg J et al. Evaluation of the orthogonal projection on latent structure model limitations caused by chemical shift variability and improved visualization of biomarker changes in 1H NMR spectroscopic metabonomic studies. Anal Chem 2005; 77: 517-526
    • (2005) Anal Chem , vol.77 , pp. 517-526
    • Cloarec, O.1    Dumas, M.E.2    Trygg, J.3
  • 35
    • 20044366919 scopus 로고    scopus 로고
    • Statistical total correlation spectroscopy: An exploratory approach for latent biomarker identification from metabolic H-1 NMR data sets
    • Cloarec O, Dumas ME, Craig A et al. Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic H-1 NMR data sets. Anal Chem 2005; 77: 1282-1289
    • (2005) Anal Chem , vol.77 , pp. 1282-1289
    • Cloarec, O.1    Dumas, M.E.2    Craig, A.3
  • 36
    • 52049118795 scopus 로고    scopus 로고
    • Correlative and quantitative 1H NMR-based metabolomics reveals specific metabolic pathway disturbances in diabetic rats
    • Zhang S, Nagana Gowda GA, Asiago V et al. Correlative and quantitative 1H NMR-based metabolomics reveals specific metabolic pathway disturbances in diabetic rats. Anal Biochem 2008; 383: 76-84
    • (2008) Anal Biochem , vol.383 , pp. 76-84
    • Zhang, S.1    Nagana Gowda, G.A.2    Asiago, V.3
  • 37
    • 79951518482 scopus 로고    scopus 로고
    • Metabolic signatures of lung cancer in biofluids: NMR-based metabonomics of urine
    • Carrola J, Rocha CM, Barros AS et al. Metabolic signatures of lung cancer in biofluids: NMR-based metabonomics of urine. J Proteome Res 2011; 10: 221-230
    • (2011) J Proteome Res , vol.10 , pp. 221-230
    • Carrola, J.1    Rocha, C.M.2    Barros, A.S.3
  • 38
    • 75149193497 scopus 로고    scopus 로고
    • Metabolic profiling of kidney and urine in rats with lithium-induced nephrogenic diabetes insipidus by H-1-NMR-based metabonomics
    • Hwang GS, Yang JY, Ryu DH et al. Metabolic profiling of kidney and urine in rats with lithium-induced nephrogenic diabetes insipidus by H-1-NMR-based metabonomics. Am J Physiol Renal Physiol 2010; 298: F461-F470
    • (2010) Am J Physiol Renal Physiol , vol.298
    • Hwang, G.S.1    Yang, J.Y.2    Ryu, D.H.3
  • 39
    • 0000174867 scopus 로고    scopus 로고
    • KarcherWet al.Model validation by permutation tests: Applications to variable selection
    • Lindgren F, Hansen B, KarcherWet al.Model validation by permutation tests: applications to variable selection. J Chemometr 1996; 10: 521-532
    • (1996) J Chemometr , vol.10 , pp. 521-532
    • Lindgren, F.1    Hansen, B.2
  • 40
    • 38949180527 scopus 로고    scopus 로고
    • Assessment of PLSDA cross validation
    • Westerhuis JA, Hoefsloot HCJ, Smit S et al. Assessment of PLSDA cross validation. Metabolomics 2008; 4: 81-89
    • (2008) Metabolomics , vol.4 , pp. 81-89
    • Westerhuis, J.A.1    Hcj, H.2    Smit, S.3
  • 41
    • 0026633014 scopus 로고
    • Glomerular cells, extracellular matrix accumulation, and the development of glomerulosclerosis in the remnant kidney model
    • Floege J, Alpers CE, Burns MW et al. Glomerular cells, extracellular matrix accumulation, and the development of glomerulosclerosis in the remnant kidney model. Lab Invest 1992; 66: 485-497
    • (1992) Lab Invest , vol.66 , pp. 485-497
    • Floege, J.1    Alpers, C.E.2    Burns, M.W.3
  • 42
    • 0033063220 scopus 로고    scopus 로고
    • The course of the remnant kidney model in mice
    • Kren S, Hostetter TH. The course of the remnant kidney model in mice. Kidney Int 1999; 56: 333-337
    • (1999) Kidney Int , vol.56 , pp. 333-337
    • Kren, S.1    Hostetter, T.H.2
  • 43
    • 33746930917 scopus 로고    scopus 로고
    • Surgical reduction of the renal mass in rats: Morphologic and functional analysis on the remnant kidney
    • Santos LS, Chin EW, Ioshii SO et al. Surgical reduction of the renal mass in rats: morphologic and functional analysis on the remnant kidney. Acta Cir Bras 2006; 21: 252-257
    • (2006) Acta Cir Bras , vol.21 , pp. 252-257
    • Santos, L.S.1    Chin, E.W.2    Ioshii, S.O.3
  • 44
    • 0348107409 scopus 로고    scopus 로고
    • The TCA cycle and tumorigenesis: The examples of fumarate hydratase and succinate dehydrogenase
    • Pollard PJ, Wortham NC, Tomlinson IP. The TCA cycle and tumorigenesis: the examples of fumarate hydratase and succinate dehydrogenase. Ann Med 2003; 35: 632-639
    • (2003) Ann Med , vol.35 , pp. 632-639
    • Pollard, P.J.1    Wortham, N.C.2    Tomlinson, I.P.3
  • 45
    • 0344305801 scopus 로고    scopus 로고
    • On the association of succinate dehydrogenase mutations with hereditary paraganglioma
    • Baysal BE. On the association of succinate dehydrogenase mutations with hereditary paraganglioma. Trends Endocrinol Metab 2003; 14: 453-459
    • (2003) Trends Endocrinol Metab , vol.14 , pp. 453-459
    • Baysal, B.E.1
  • 46
    • 0021024932 scopus 로고
    • Carnitine-metabolism and functions
    • Bremer J. Carnitine-metabolism and functions. Physiol Rev 1983; 63: 1420-1480
    • (1983) Physiol Rev , vol.63 , pp. 1420-1480
    • Bremer, J.1
  • 47
    • 0018274001 scopus 로고
    • Carnitine deficiency induced during intermittent haemodialysis for renal failure
    • Bohmer T, Bergrem H, Eiklid K. Carnitine deficiency induced during intermittent haemodialysis for renal failure. Lancet 1978; 1: 126-128
    • (1978) Lancet , vol.1 , pp. 126-128
    • Bohmer, T.1    Bergrem, H.2    Eiklid, K.3
  • 48
    • 0034537397 scopus 로고    scopus 로고
    • Organic osmolyte channels: A comparative view
    • Junankar PR, Kirk K. Organic osmolyte channels: a comparative view. Cell Physiol Biochem 2000; 10: 355-360
    • (2000) Cell Physiol Biochem , vol.10 , pp. 355-360
    • Junankar, P.R.1    Kirk, K.2
  • 49
    • 0025824198 scopus 로고
    • Accumulation of glycerophosphocholine (GPC) by renal cells: Osmotic regulation of GPC:choline phosphodiesterase
    • Zablocki K, Miller SP, Garcia-Perez A et al. Accumulation of glycerophosphocholine (GPC) by renal cells: osmotic regulation of GPC:choline phosphodiesterase. Proc Natl Acad Sci USA 1991; 88: 7820-7824
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 7820-7824
    • Zablocki, K.1    Miller, S.P.2    Garcia-Perez, A.3
  • 50
    • 0024320305 scopus 로고
    • Brain taurine content as a function of cerebral metabolic rate: Osmotic regulation of glucose derived water production
    • van Gelder NM. Brain taurine content as a function of cerebral metabolic rate: osmotic regulation of glucose derived water production. Neurochem Res 1989; 14: 495-497
    • (1989) Neurochem Res , vol.14 , pp. 495-497
    • Van Gelder, N.M.1
  • 51
    • 0029160798 scopus 로고
    • Changes in organic solutes, volume, energy state, and metabolism associated with osmotic stress in a glial cell line: A multinuclear NMR study
    • FlogelU,Niendorf T, SerkowaNet al. Changes in organic solutes, volume, energy state, and metabolism associated with osmotic stress in a glial cell line: a multinuclear NMR study. Neurochem Res 1995; 20: 793-802
    • (1995) Neurochem Res , vol.20 , pp. 793-802
    • Flogel, U.1    Niendorf, T.2    Serkowa, N.3
  • 52
    • 77953695390 scopus 로고    scopus 로고
    • Serum branched-chain amino acid to histidine ratio: A novel metabolomic biomarker of knee osteoarthritis
    • Zhai G, Wang-Sattler R, Hart DJ et al. Serum branched-chain amino acid to histidine ratio: a novel metabolomic biomarker of knee osteoarthritis. Ann Rheum Dis 2010; 69: 1227-1231
    • (2010) Ann Rheum Dis , vol.69 , pp. 1227-1231
    • Zhai, G.1    Wang-Sattler, R.2    Hart, D.J.3
  • 53
    • 33644784880 scopus 로고    scopus 로고
    • High-resolution magic angle spinning H-1 NMR spectroscopy and reverse transcription-PCR analysis of apoptosis in a rat glioma
    • Griffin JL, Blenkiron C, Valonen PK et al. High-resolution magic angle spinning H-1 NMR spectroscopy and reverse transcription-PCR analysis of apoptosis in a rat glioma. Anal Chem 2006; 78: 1546-1552
    • (2006) Anal Chem , vol.78 , pp. 1546-1552
    • Griffin, J.L.1    Blenkiron, C.2    Valonen, P.K.3
  • 54
    • 0037128692 scopus 로고    scopus 로고
    • Apoptosis is associated with triacyglycerol accumulation in Jurkat T-cells
    • Al-Saffar NMS, Titley JC, Robertson D et al. Apoptosis is associated with triacyglycerol accumulation in Jurkat T-cells. Br J Cancer 2002; 86: 963-970
    • (2002) Br J Cancer , vol.86 , pp. 963-970
    • Al-Saffar, N.M.S.1    Titley, J.C.2    Robertson, D.3
  • 55
    • 0028176651 scopus 로고
    • Oxidative stress as a mediator of apoptosis
    • Buttke TM, Sandstrom PA. Oxidative stress as a mediator of apoptosis. Immunol Today 1994; 15: 7-10
    • (1994) Immunol Today , vol.15 , pp. 7-10
    • Buttke, T.M.1    Sandstrom, P.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.