Bif-1 is overexpressed in hepatocellular carcinoma and correlates with shortened patient survival

Oncology Letters

Volumn 3, Issue 4, 2012, Pages 851-854

  Fan, Rengen ^a,b   Miao, Yufeng ^b   Shan, Xiangxiang ^b   Qian, Haixin ^a   Song, Changzhi ^b   Wu, Guangzhou ^b   Chen, Yan ^b   Zha, Wenzhang ^b  

^a THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^b Yancheng City No1 People's Hospital   (China)

Author keywords

Autophagy; Bax interacting factor 1; Hepatocellular carcinoma

Indexed keywords

BAX INTERACTING FACTOR 1; PROTEIN BAX; TUMOR MARKER; UNCLASSIFIED DRUG;

ARTICLE; CANCER PROGNOSIS; CANCER SURVIVAL; CONTROLLED STUDY; CYTOPLASM; DISEASE MARKER; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PROTEIN EXPRESSION; SURVIVAL TIME; TUMOR DIFFERENTIATION;

EID: 84863163331     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2012.562     Document Type: Article

References (32)

1. Ercolani G, Grazi GL, Ravaioli M, et al: Liver resection for hepatocellular carcinoma on cirrhosis: univariate and multivariate analysis of risk factors for intrahepatic recurrence. Ann Surg 4: 536-543, 2003.
2. Bosch FX, Ribes J and Borras J: Epidemiology of primary liver cancer. Semin Liver Dis 3: 271-285, 1999.
3. Llovet JM, Burroughs A and Bruix J: Hepatocellular carcinoma. Lancet 9399: 1907-1917, 2003.
4. Arii S, Tanaka J, Yamazoe Y, et al: Predictive factors for intrahepatic recurrence of hepatocellular carcinoma after partial hepatectomy. Cancer 4: 913-919, 1992.
5. Pierrat B, Simonen M, Cueto M, Mestan J, Ferrigno P and Heim J: SH3GLB, a new endophilin-related protein family featuring an SH3 domain. Genomics 2: 222-234, 2001.
6. Cuddeback SM, Yamaguchi H, Komatsu K, et al: Molecular cloning and characterization of Bif-1. A novel Src homology 3 domain-containing protein that associates with Bax. J Biol Chem 23: 20559-20565, 2001.
7. Coppola D, Helm J, Ghayouri M, Malafa MP and Wang HG: Down-regulation of Bax-interacting factor 1 in human pancreatic ductal adenocarcinoma. Pancreas 3: 433-437, 2011.
8. Schlauder SM, Calder KB, Khalil FK, Passmore L, Mathew RA and Morgan MB: Bif-1 and Bax expression in cutaneous merkel cell carcinoma. J Cutan Pathol 1: 21-25, 2009.
9. Coppola D, Khalil F, Eschrich SA, Boulware D, Yeatman T and Wang HG: Down-regulation of Bax-interacting factor-1 in colorectal adenocarcinoma. Cancer 10: 2665-2670, 2008.
10. Coppola D, Oliveri C, Sayegh Z, Boulware D, Takahashi Y, Pow-Sang J, Djeu JY and Wang HG: Bax-interacting factor-1 expression in prostate cancer. Clin Genitourin Cancer 2: 117-121, 2008.
11. Kim SY, Oh YL, Kim KM, Jeong EG, Kim MS, Yoo NJ and Lee SH: Decreased expression of Bax-interacting factor-1 (Bif-1) in invasive urinary bladder and gallbladder cancers. Pathology 6: 553-557, 2008.
12. Lee JW, Jeong, EG, Soung YH, Nam SW, Lee JY, Yoo NJ and Lee SH: Decreased expression of tumour suppressor Bax-interacting factor-1 (Bif-1), a Bax activator, in gastric carcinomas. Pathology 4: 312-315, 2006.
13. Iguchi T, Aishima S, Taketomi A, et al: Fascin overexpression is involved in carcinogenesis and prognosis of human intrahepatic cholangiocarcinoma: immunohistochemical and molecular analysis. Hum Pathol 2: 174-180, 2009.
14. Takahashi Y, Coppola D, Matsushita N, et al: Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis. Nat Cell Biol 10: 1142-1151, 2007.
15. Takahashi Y, Meyerkord CL and Wang HG: BARgaining membranes for autophagosome formation: regulation of autophagy and tumorigenesis by Bif-1/Endophilin B1. Autophagy 1: 121-124, 2008.
16. Noda T, Kim J, Huang WP, et al: Apg9p/Cvt7p is an integral membrane protein required for transport vesicle formation in the Cvt and autophagy pathways. J Cell Biol 3: 465-480, 2000.
17. Yamada T, Carson AR, Caniggia I, et al: Endothelial nitric-oxide synthase antisense (NOS3AS) gene encodes an autophagy-related protein (APG9-like2) highly expressed in trophoblast. J Biol Chem 18: 18283-18290, 2005.
18. Young AR, Chan EY, Hu XW, et al: Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes. J Cell Sci 18: 3888-3900, 2006.
19. Levine B and Klionsky DJ: Development by self-digestion: molecular mechanisms and biological functions of autophagy. Dev Cell 4: 463-477, 2004.
20. Høyer-Hansen M and Jaattela M: AMP-activated protein kinase: a universal regulator of autophagy? Autophagy 4: 381-383, 2007.
21. Meijer AJ and Codogno P: Signalling and autophagy regulation in health, aging and disease. Mol Aspects Med 5-6: 411-425, 2006.
22. Kirkegaard K, Taylor MP and Jackson WT: Cellular autophagy: surrender, avoidance and subversion by microorganisms. Nat Rev Microbiol 4: 301-314, 2004.
23. Kondo Y, Kanzawa T, Sawaya R and Kondo S: The role of autophagy in cancer development and response to therapy. Nat Rev Cancer 5: 726-734, 2005.
24. Cuervo AM: Autophagy: in sickness and in health. Trends Cell Biol 2: 70-77, 2004.
25. Scriven P, Brown NJ, Pockley AG and Wyld L: The unfolded protein response and cancer: a brighter future unfolding? J Mol Med 4: 331-341, 2007.
26. Moreno-Sánchez R, Rodríguez-Enríquez S, Marín-Hernández A and Saavedra E: Energy metabolism in tumor cells. Febs J 6: 1393-1418, 2007.
27. Kato K, Ogura T, Kishimoto A, Minegishi Y, Nakajima N, Miyazaki M and Esumi H: Critical roles of AMP-activated protein kinase in constitutive tolerance of cancer cells to nutrient deprivation and tumor formation. Oncogene 39: 6082-6090, 2002.
28. Pouyssegur J, Dayan F and Mazure NM: Hypoxia signalling in cancer and approaches to enforce tumour regression. Nature 7092: 437-443, 2006.
29. Degenhardt K, Mathew R, Beaudoin B, et al: Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis. Cancer Cell 1: 51-64, 2006.
30. White E: Role of the metabolic stress responses of apoptosis and autophagy in tumor suppression. Ernst Schering Found Symp Proc 4: 23-34, 2007.
31. Chen N and Karantza-Wadsworth V: Role and regulation of autophagy in cancer. Biochim Biophys Acta 9: 1516-1523, 2009.
32. Ogier-Denis E, Houri JJ, Bauvy C and Codogno P: Guanine nucleotide exchange on heterotrimeric Gi3 protein controls autophagic sequestration in HT-29 cells. J Biol Chem 45: 28593-28600, 1996.