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Volumn 35, Issue 1, 2012, Pages 141-152

Analytical LC-MS/MS method for ezetimibe and its application for pharmacokinetic study

Author keywords

ezetimibe; HPLC; human plasma; LC MS MS; pharmacokinetics; tandem mass

Indexed keywords

EZETIMIBE; HPLC; HUMAN PLASMAS; LC-MS/MS; TANDEM MASS;

EID: 84863150703     PISSN: 10826076     EISSN: 1520572X     Source Type: Journal    
DOI: 10.1080/10826076.2011.597065     Document Type: Article
Times cited : (10)

References (28)
  • 4
    • 0034003105 scopus 로고    scopus 로고
    • Comparison of the activity and disposition of the novel cholesterol absorption inhibitor, SCH58235, and its glucuronide, SCH60663
    • van Heek, M.; Farley, C.; Compton, D. S.; Hoos, L.; Alton, K. B.; Sybertz, E. J.; Davis, H. R. Jr. Comparison of the Activity and Disposition of the Novel Cholesterol Absorption Inhibitor, SCH58235, and Its Glucuronide, SCH60663. Br. J. Pharmacol. 2000, 129 (8), 1748-1754. (Pubitemid 30219019)
    • (2000) British Journal of Pharmacology , vol.129 , Issue.8 , pp. 1748-1754
    • Van Heek, M.1    Farley, C.2    Compton, D.S.3    Hoos, L.4    Alton, K.B.5    Sybertz, E.J.6    Davis Jr., H.R.7
  • 6
    • 0642280885 scopus 로고    scopus 로고
    • The pharmacokinetics of ezetimibe
    • Simard, C.; Turgeon, J. The Pharmacokinetics of Ezetimibe. Can. J. Clin. Pharmacol. 2003, 10 (Suppl. 1), 13A-20A.
    • (2003) Can. J. Clin. Pharmacol. , vol.10 , Issue.SUPPL. 1
    • Simard, C.1    Turgeon, J.2
  • 8
    • 23944443039 scopus 로고    scopus 로고
    • Development and validation of a reversed-phase HPLC method for the determination of ezetimibe in pharmaceutical dosage forms
    • DOI 10.1016/j.jpba.2005.04.026, PII S0731708505002918
    • Sistla, R.; Tata, V. S.; Kashyap, Y. V.; Chandrasekar, D.; Diwan, P. V. Development and Validation of a Reversed-Phase HPLC Method for the Determination of Ezetimibe in Pharmaceutical Dosage Forms. J. Pharm. Biomed. Anal. 2005, 39 (3-4), 517-522. (Pubitemid 41196057)
    • (2005) Journal of Pharmaceutical and Biomedical Analysis , vol.39 , Issue.3-4 , pp. 517-522
    • Sistla, R.1    Tata, V.S.S.K.2    Kashyap, Y.V.3    Chandrasekar, D.4    Diwan, P.V.5
  • 10
    • 32944457380 scopus 로고    scopus 로고
    • Liquid chromatography-negative ion electrospray tandem mass spectrometry method for the quantification of ezetimibe in human plasma
    • DOI 10.1016/j.jpba.2005.07.053, PII S0731708505005546
    • Li, S.; Liu, G.; Jia, J.; Li, X.; Yu, C. Liquid Chromatography-Negative Ion Electrospray Tandem Mass Spectrometry Method for the Quantification of Ezetimibe in Human Plasma. J. Pharm. Biomed. Anal. 2006, 40 (4), 987-992. (Pubitemid 43257906)
    • (2006) Journal of Pharmaceutical and Biomedical Analysis , vol.40 , Issue.4 , pp. 987-992
    • Li, S.1    Liu, G.2    Jia, J.3    Li, X.4    Yu, C.5
  • 12
    • 2942545923 scopus 로고    scopus 로고
    • Analysis of bioequivalence study using a log-transformed model
    • Lee, Y. J.; Kim, Y. G.; Lee, M. G.; Chung, S. J.; Lee, M. H.; Shim, C. K. Analysis of Bioequivalence Study Using a Log-transformed Model. Yakhakhoeji 2000, 44 (4), 308-314.
    • (2000) Yakhakhoeji , vol.44 , Issue.4 , pp. 308-314
    • Lee, Y.J.1    Kim, Y.G.2    Lee, M.G.3    Chung, S.J.4    Lee, M.H.5    Shim, C.K.6
  • 14
    • 0031864410 scopus 로고    scopus 로고
    • Contribution of two missense mutations (G71R and Y486D) of the bilirubin UDP glycosyltransferase (UGT1A1) gene to phenotypes of Gilbert's syndrome and Crigler-Najjar syndrome type II
    • DOI 10.1016/S0925-4439(98)00013-1, PII S0925443998000131
    • Yamamoto, K.; Sato, H.; Fujiyama, Y.; Doida, Y.; Bamba, T. Contribution of Two Missense Mutations (G71 R and Y486D) of the Bilirubin UDP Glycosyltransferase (UGT1A1) Gene to Phenotypes of Gilbert's Syndrome and Crigler-Najjar Syndrome Type II. Biochim. Biophys. Acta. 1998, 1406 (3), 267-273. (Pubitemid 28269309)
    • (1998) Biochimica et Biophysica Acta - Molecular Basis of Disease , vol.1406 , Issue.3 , pp. 267-273
    • Yamamoto, K.1    Sato, H.2    Fujiyama, Y.3    Doida, Y.4    Bamba, T.5
  • 16
    • 0030030762 scopus 로고    scopus 로고
    • Genetic variation in bilirubin UDP-glucuronosyltransferase gene promoter and Gilbert's syndrome
    • DOI 10.1016/S0140-6736(96)91273-8
    • Monaghan, G.; Ryan, M.; Seddon, R.; Hume, R.; Burchell, B. Genetic Variation in Bilirubin UPD-glucuronosyltransferase Gene Promoter and Gilbert's Syndrome. Lancet. 1996, 347 (9001), 578-581. (Pubitemid 26070740)
    • (1996) Lancet , vol.347 , Issue.9001 , pp. 578-581
    • Monaghan, G.1    Ryan, M.2    Seddon, R.3    Hume, R.4    Burchell, B.5
  • 17
    • 0032519431 scopus 로고    scopus 로고
    • Genetic predisposition to the metabolism of irinotecan (CPT-11): Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes
    • Iyer, L.; King, C. D.; Whitingtone, P. F.; Green, D.; Roy, S. K.; Tephly, B. L.; Ratain, M. J. Genetic Predisposition to the Metabolism of Irinotecan (CPT-11). Role of Uridine Diphosphate Glucuronosyltransferase Isoform 1A1 in the Glucuronidation of Its Active Metabolite (SN-38) in Human Liver Microsomes. J. Clin. Invest. 1998, 101 (4), 847-854. (Pubitemid 28096082)
    • (1998) Journal of Clinical Investigation , vol.101 , Issue.4 , pp. 847-854
    • Iyer, L.1    King, C.D.2    Whitington, P.F.3    Green, M.D.4    Roy, S.K.5    Tephly, T.R.6    Coffman, B.L.7    Ratain, M.J.8
  • 18
    • 0032934383 scopus 로고    scopus 로고
    • Phenotype-genotype correlation of in vitro SN-38 (active metabolite of irinotecan) and bilirubin glucuronidation in human liver tissue with UGT1A1 promoter polymorphism
    • DOI 10.1016/S0009-9236(99)70078-0
    • Iyer, L.; Hall, D.; Das, S.; Mortell, M. A.; Ramírez, J.; Kim, S.; Di Rienzo, A.; Ratain, M. J. Phenotype-Genotype Correlation of in vitro SN-38 (Active Metabolite of Irinotecan) and Bilirubin Glucuronidation in Human Liver Tissue with UGT1A1 Promoter Polymorphism. Clin. Pharmacol. Ther. 1999, 65 (5), 576-582. (Pubitemid 29237332)
    • (1999) Clinical Pharmacology and Therapeutics , vol.65 , Issue.5 , pp. 576-582
    • Iyer, L.1    Hall, D.2    Das, S.3    Mortell, M.A.4    Ramirez, J.5    Kim, S.6    Di Rienzo, A.7    Ratain, M.J.8
  • 19
  • 20
    • 0034652640 scopus 로고    scopus 로고
    • Genetic polymorphisms in uridine diphospho-glucuronosyltransferase 1A1 and association with breast cancer among African Americans
    • Guillemette, C.; Millikan, R. C.; Newman, B.; Housman, D. E. Genetic Polymorphisms in Uridine Diphospho-Glucuronosyltransferase 1A1 and Association with Breast Cancer Among African Americans. Cancer. Res. 2000, 60 (4), 950-956. (Pubitemid 30129531)
    • (2000) Cancer Research , vol.60 , Issue.4 , pp. 950-956
    • Guillemette, C.1    Millikan, R.C.2    Newman, B.3    Housman, D.E.4
  • 21
    • 0035147198 scopus 로고    scopus 로고
    • Chemotherapy-induced unconjugated hyperbilirubinemia caused by a mutation of the bilirubin uridine-5′-diphosphate-glucuronosyltransferase gene
    • DOI 10.1097/00043426-200101000-00010
    • Maruo, Y.; Sato, H.; Bamba, N.; Iwai, M.; Sawa, H.; Fujino, H.; Taga, T.; Ota, S.; Shimada, M. Chemotherapy-Induced Unconjugated Hyperbilirubinemia Caused by a Mutation of the Bilirubin Uridine-50-diphosphate- glucuronosyltransferase Gene. J. Pediatr. Hematol. Oncol. 2001, 23 (1), 45-47. (Pubitemid 32124983)
    • (2001) Journal of Pediatric Hematology/Oncology , vol.23 , Issue.1 , pp. 45-47
    • Maruo, Y.1    Sato, H.2    Bamba, N.3    Iwai, M.4    Sawa, H.5    Fujino, H.6    Taga, T.7    Ota, S.8    Shimada, M.9
  • 23
    • 0027433317 scopus 로고
    • Complementary deoxyribonucleic acid cloning and expression of a human liver uridine diphosphate-glucuronosyltransferase glucuronidating carboxylic acid-containing drugs
    • Jin, C.; Miners, J. O.; Lillywhite, K. J.; Mackenzie, P. I. Complementary Deoxyribo-Nucleic Acid Cloning and Expression of a Human Liver Uridine Diphosphate-Glucuronosyltransferase Glucuronidating Carboxylic Acid-Containing Drugs. J. Pharmacol. Exp. Ther. 1993, 264 (1), 475-479. (Pubitemid 23309239)
    • (1993) Journal of Pharmacology and Experimental Therapeutics , vol.264 , Issue.1 , pp. 475-479
    • Jin, C.1    Miners, J.O.2    Lillywhite, K.J.3    Mackenzie, P.I.4
  • 24
    • 0033645752 scopus 로고    scopus 로고
    • Genetic polymorphism of UDP-glucuronosyltransferase 2B7 (UGT2B7) at amino acid 268: Ethnic diversity of alleles and potential clinical significance
    • Bhasker, C. R.; McKinnon, W.; Stone, A.; Lo, A. C.; Kubota, T.; Ishizaki, T.; Miners, J. O. Genetic Polymorphism of UDP-glucuronosyltransferase 2B7 (UGT2B7) at Amino Acid 268: Ethnic Diversity of Alleles and Potential Clinical Significance. Pharmacogenetics 2000, 10 (8), 679-685.
    • (2000) Pharmacogenetics , vol.10 , Issue.8 , pp. 679-685
    • Bhasker, C.R.1    McKinnon, W.2    Stone, A.3    Lo, A.C.4    Kubota, T.5    Ishizaki, T.6    Miners, J.O.7
  • 25
    • 0030795936 scopus 로고    scopus 로고
    • 85): A UDP-glucuronosyltransferase encoded by a polymorphic gene
    • DOI 10.1097/00008571-199708000-00007
    • Lévesque, E.; Beaulieu, M.; Green, M. D.; Tephly, T. R.; Bélanger, A.; Hum, D. W. Isolation and Characterization of UGT2B15(Y85): a UDP-glucuronosyltransferase Encoded by a Polymorphic Gene. Pharmacogenetics 1997, 7 (4), 317-325. (Pubitemid 27356932)
    • (1997) Pharmacogenetics , vol.7 , Issue.4 , pp. 317-325
    • Levesque, E.1    Beaulieu, M.2    Green, M.D.3    Tephly, T.R.4    Belanger, A.5    Hum, D.W.6
  • 26
    • 33644505139 scopus 로고    scopus 로고
    • Intestinal expression of P-glycoprotein (ABCB1), multidrug resistance associated protein 2 (ABCC2), and uridine diphosphate-glucuronosyltransferase 1A1 predicts the disposition and modulates the effects of the cholesterol absorption inhibitor ezetimibe in humans
    • Oswald, S.; Haenisch, S.; Fricke, C.; Sudhop, T.; Remmler, C.; Giessmann, T.; Jedlitschky, G.; Adam, U.; Dazert, E.; Warzok, R.; Wacke, W.; Cascorbi, I.; Kroemer, H. K.; Weitschies, W.; von Bergmann, K.; Siegmund, W. Intestinal Expression of P-glycoprotein (ABCB1), Multidrug Resistance Associated Protein 2 (ABCC2), and Uridine Diphosphate-Glucuronosyltransferase 1A1 Predicts the Disposition and Modulates the Effects of the Cholesterol Absorption Inhibitor Ezetimibe in Humans. Clin. Pharmacol. Ther. 2006, 79 (3), 206-217.
    • (2006) Clin. Pharmacol. Ther. , vol.79 , Issue.3 , pp. 206-217
    • Oswald, S.1    Haenisch, S.2    Fricke, C.3    Sudhop, T.4    Remmler, C.5    Giessmann, T.6    Jedlitschky, G.7    Adam, U.8    Dazert, E.9    Warzok, R.10    Wacke, W.11    Cascorbi, I.12    Kroemer, H.K.13    Weitschies, W.14    Von Bergmann, K.15    Siegmund, W.16
  • 27
    • 33751103450 scopus 로고    scopus 로고
    • Disposition and sterol-lowering effect of ezetimibe are influenced by single-dose coadministration of rifampin, an inhibitor of multidrug transport proteins
    • DOI 10.1016/j.clpt.2006.07.006, PII S0009923606003006
    • Oswald, S.; Giessmann, T.; Luetjohann, D.; Wegner, D.; Rosskopf, D.; Weitschies, W.; Siegmund, W. Disposition and Sterol-Lowering Effect of Ezetimibe are Influenced by Single-Dose Coadministration of Rifampin, an Inhibitor of Multidrug Transport Proteins. Clin. Pharmacol. Ther. 2006, 80 (5), 477-485. (Pubitemid 44767877)
    • (2006) Clinical Pharmacology and Therapeutics , vol.80 , Issue.5 , pp. 477-485
    • Oswald, S.1    Giessmann, T.2    Luetjohann, D.3    Wegner, D.4    Rosskopf, D.5    Weitschies, W.6    Siegmund, W.7


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