IGF binding protein-6 expression in vascular endothelial cells is induced by hypoxia and plays a negative role in tumor angiogenesis

International Journal of Cancer

Volumn 130, Issue 9, 2012, Pages 2003-2012

  Zhang, Chunyang ^a   Lu, Ling ^a   Li, Yun ^a   Wang, Xianlei ^a,b   Zhou, Jianfeng ^a   Liu, Yunzhang ^a   Fu, Ping ^c   Gallicchio, Marisa A ^c   Bach, Leon A ^c   Duan, Cunming ^d  

^a OCEAN UNIVERSITY OF CHINA   (China)

^b National Oceanographic Center   (China)

^c MONASH UNIVERSITY   (Australia)

^d UNIVERSITY OF MICHIGAN   (United States)

Author keywords

angiogenesis; endothelial cells; hypoxia; IGFBP 6; insulin like growth factor; VEGF; zebrafish

Indexed keywords

GREEN FLUORESCENT PROTEIN; SOMATOMEDIN BINDING PROTEIN 6; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CANCER CELL; CELL CULTURE; CELL HYPOXIA; CONTROLLED STUDY; EMBRYO; ENDOTHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RHABDOMYOSARCOMA; TUMOR VASCULARIZATION; TUMOR XENOGRAFT; VASCULAR ENDOTHELIUM; ZEBRA FISH;

ANIMALS; CELL HYPOXIA; CELL LINE, TUMOR; ENDOTHELIAL CELLS; FEMALE; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 6; INSULIN-LIKE GROWTH FACTOR I; MICE; MICE, NUDE; NEOVASCULARIZATION, PATHOLOGIC; RATS; RHABDOMYOSARCOMA; VASCULAR ENDOTHELIAL GROWTH FACTOR A; ZEBRAFISH;

EID: 84863147042     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.26201     Document Type: Article

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