Identification of IGFBP-6 as an effector of the tumor suppressor activity of SEMA3B

Oncogene

Volumn 27, Issue 51, 2008, Pages 6581-6589

  Koyama, N ^a   Zhang, J ^a,b   Huqun, ^a   Miyazawa, H ^a   Tanaka, T ^a   Su, X ^b   Hagiwara, K ^a  

^a SAITAMA MEDICAL UNIVERSITY   (Japan)

^b INNER MONGOLIA MEDICAL COLLEGE   (China)

Author keywords

B catenin; Insulin like growth factorbinding protein 6; Microarray; Semaphorin 3B; Tumor suppression

Indexed keywords

BETA CATENIN; COMPLEMENTARY DNA; SEMAPHORIN; SEMAPHORIN 3B; SMALL INTERFERING RNA; SOMATOMEDIN B; SOMATOMEDIN BINDING PROTEIN 6; T CELL FACTOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; COLONY FORMATION; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; MICROARRAY ANALYSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; SIGNAL TRANSDUCTION;

BETA CATENIN; CELL PROLIFERATION; CELLS, CULTURED; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 6; MEMBRANE GLYCOPROTEINS; PROTEIN BINDING; RNA, SMALL INTERFERING; SEMAPHORINS; SIGNAL TRANSDUCTION; TCF TRANSCRIPTION FACTORS; TRANSFECTION; TUMOR STEM CELL ASSAY; TUMOR SUPPRESSOR PROTEINS;

EID: 55249102630     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2008.263     Document Type: Article

References (40)

1. Bach LA. (1999). Insulin-like growth factor binding protein-6: the 'forgotten' binding protein? Horm Metab Res 31: 226-234.
2. Bach LA, Hsieh S, Brown AL, Rechler MM. (1994). Recombinant human insulin-like growth factor (IGF)-binding protein-6 inhibits IGF-II-induced differentiation of L6A1 myoblasts. Endocrinology 135: 2168-2176.
3. Bach LA, Salemi R, Leeding KS. (1995). Roles of insulin-like growth factor (IGF) receptors and IGF-binding proteins in IGF-II-induced proliferation and differentiation of L6A1 rat myoblasts. Endocrinology 136: 5061-5069.
4. Barz T, Hoffmann A, Panhuysen M, Spengler D. (2006). Peroxisome proliferator-activated receptor gamma is a Zac target gene mediating Zac antiproliferation. Cancer Res 66: 11975-11982.
5. Behar O, Golden JA, Mashimo H, Schoen FJ, Fishman MC. (1996). Semaphorin III is needed for normal patterning and growth of nerves, bones and heart. Nature 383: 525-528.
6. Castro-Rivera E, Ran S, Thorpe P, Minna JD. (2004). Semaphorin 3B (SEMA3B) induces apoptosis in lung and breast cancer, whereas VEGF165 antagonizes this effect. Proc Natl Acad Sci USA 101: 11432-11437.
7. Chow LS, Lam CW, Chan SY, Tsao SW, To KF, Tong SF et al. (2006). Identification of RASSF1A modulated genes in nasopharyngeal carcinoma. Oncogene 25: 310-316.
8. Christensen CR, Klingelhofer J, Tarabykina S, Hulgaard EF, Kramerov D, Lukanidin E. (1998). Transcription of a novel mouse semaphorin gene, M-semaH, correlates with the metastatic ability of mouse tumor cell lines. Cancer Res 58: 1238-1244.
9. Clevers H. (2006). Wnt/beta-catenin signaling in development and disease. Cell 127: 469-480.
10. Denys H, Jadidizadeh A, Amini Nik S, Van Dam K, Aerts S, Alman BA et al. (2004). Identification of IGFBP-6 as a significantly downregulated gene by beta-catenin in desmoid tumors. Oncogene 23: 654-664.
11. Feng X, Bonni S, Riabowol K. (2006). HSP70 induction by ING proteins sensitizes cells to tumor necrosis factor alpha receptor-mediated apoptosis. Mol Cell Biol 26: 9244-9255.
12. Firth SM, Baxter RC. (2002). Cellular actions of the insulin-like growth factor binding proteins. Endocr Rev 23: 824-854.
13. Gallicchio MA, Kneen M, Hall C, Scott AM, Bach LA. (2001). Overexpression of insulin-like growth factor binding protein-6 inhibits rhabdomyosarcoma growth in vivo. Int J Cancer 94: 645-651.
14. Grellier P, De Galle B, Babajko S. (1998). Expression of insulin-like growth factor-binding protein 6 complementary DNA alters neuroblastoma cell growth. Cancer Res 58: 1670-1676.
15. Gu C, Yoshida Y, Livet J, Reimert DV, Mann F, Merte J et al. (2005). Semaphorin 3E and plexin-D1 control vascular pattern independently of neuropilins. Science 307: 265-268.
16. Guttmann-Raviv N, Kessler O, Shraga-Heled N, Lange T, Herzog Y, Neufeld G. (2006). The neuropilins and their role in tumorigenesis and tumor progression. Cancer Lett 231: 1-11.
17. Hall KT, Boumsell L, Schultze JL, Boussiotis VA, Dorfman DM, Cardoso AA et al. (1996). Human CD100, a novel leukocyte semaphorin that promotes B-cell aggregation and differentiation. Proc Natl Acad Sci USA 93: 11780-11785.
18. He Z, Tessier-Lavigne M. (1997). Neuropilin is a receptor for the axonal chemorepellent Semaphorin III. Cell 90: 739-751.
19. Kannan K, Kaminski N, Rechavi G, Jakob-Hirsch J, Amariglio N, Givol D. (2001). DNA microarray analysis of genes involved in p53 mediated apoptosis: activation of Apaf-1. Oncogene 20: 3449-3455.
20. Kato M, Ishizaki A, Hellman U, Wernstedt C, Kyogoku M, Miyazono K et al. (1995). A human keratinocyte cell line produces two autocrine growth inhibitors, transforming growth factor-beta and insulin-like growth factor binding protein-6, in a calcium- and cell density-dependent manner. J Biol Chem 270: 12373-12379.
21. Koike H, Ito K, Takezawa Y, Oyama T, Yamanaka H, Suzuki K. (2005). Insulin-like growth factor binding protein-6 inhibits prostate cancer cell proliferation: implication for anticancer effect of diethylstilbestrol in hormone refractory prostate cancer. Br J Cancer 92: 1538-1544.
22. Kolodkin AL, Matthes DJ, Goodman CS. (1993). The semaphorin genes encode a family of transmembrane and secreted growth cone guidance molecules. Cell 75: 1389-1399.
23. Leng SL, Leeding KS, Whitehead RH, Bach LA. (2001). Insulin-like growth factor (IGF)-binding protein-6inhibits IGF-II-induced but not basal proliferation and adhesion of LIM 1215 colon cancer cells. Mol Cell Endocrinol 174: 121-127.
24. Mac Gabhann F, Popel AS. (2006). Targeting neuropilin-1 to inhibit VEGF signaling in cancer: comparison of therapeutic approaches. PLoS Comput Biol 2: e180.
25. Martin JL, Willetts KE, Baxter RC. (1990). Purification and properties of a novel insulin-like growth factor-II binding protein from transformed human fibroblasts. J Biol Chem 265: 4124-4130.
26. Miao HQ, Soker S, Feiner L, Alonso JL, Raper JA, Klagsbrun M. (1999). Neuropilin-1 mediates collapsin-1/semaphorin III inhibition of endothelial cell motility: functional competition of collapsin-1 and vascular endothelial growth factor-165. J Cell Biol 146: 233-242.
27. Nasarre P, Kusy S, Constantin B, Castellani V, Drabkin HA, Bagnard D et al. (2005). Semaphorin SEMA3F has a repulsing activity on breast cancer cells and inhibits E-cadherin-mediated cell adhesion. Neoplasia 7: 180-189.
28. Nelson WJ, Nusse R. (2004). Convergence of Wnt, beta-catenin, and cadherin pathways. Science 303: 1483-1487.
29. Ochi K, Mori T, Toyama Y, Nakamura Y, Arakawa H. (2002). Identification of semaphorin3B as a direct target of p53. Neoplasia 4: 82-87.
30. Pasterkamp RJ, De Winter F, Holtmaat AJ, Verhaagen J. (1998). Evidence for a role of the chemorepellent semaphorin III and its receptor neuropilin-1 in the regeneration of primary olfactory axons. J Neurosci 18: 9962-9976.
31. Scholl FA, Betts DR, Niggli FK, Schafer BW. (2000). Molecular features of a human rhabdomyosarcoma cell line with spontaneous metastatic progression. Br J Cancer 82: 1239-1245.
32. Sekido Y, Bader S, Latif F, Chen JY, Duh FM, Wei MH et al. (1996). Human semaphorins A(V) and IV reside in the 3p21.3 small cell lung cancer deletion region and demonstrate distinct expression patterns. Proc Natl Acad Sci USA 93: 4120-4125.
33. Soker S, Fidder H, Neufeld G, Klagsbrun M. (1996). Characterization of novel vascular endothelial growth factor (VEGF) receptors on tumor cells that bind VEGF165 via its exon 7-encoded domain. J Biol Chem 271: 5761-5767.
34. Soker S, Takashima S, Miao HQ, Neufeld G, Klagsbrun M. (1998). Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell 92: 735-745.
35. Sueoka N, Lee HY, Wiehle S, Cristiano RJ, Fang B, Ji L et al. (2000). Insulin-like growth factor binding protein-6 activates programmed cell death in non-small cell lung cancer cells. Oncogene 19: 4432-4436.
36. Tomizawa Y, Sekido Y, Kondo M, Gao B, Yokota J, Roche J et al. (2001). Inhibition of lung cancer cell growth and induction of apoptosis after reexpression of 3p21.3 candidate tumor suppressor gene SEMA3B. Proc Natl Acad Sci USA 98: 13954-13959.
37. Tran TS, Kolodkin AL, Bharadwaj R. (2007). Semaphorin regulation of cellular morphology. Annu Rev Cell Dev Biol 23: 263-292.
38. Usami N, Sekido Y, Maeda O, Yamamoto K, Minna JD, Hasegawa Y et al. (2003). Beta-catenin inhibits cell growth of a malignant mesothelioma cell line, NCI-H28, with a 3p21.3 homozygous deletion. Oncogene 22: 7923-7930.
39. Yao R, Wang Y, Lubet RA, You M. (2002). Differentially expressed genes associated with mouse lung tumor progression. Oncogene 21: 5814-5821.
40. Yu J, Zhang L, Hwang PM, Kinzler KW, Vogelstein B. (2001). PUMA induces the rapid apoptosis of colorectal cancer cells. Mol Cell 7: 673-682.