Antibody directs properdin-dependent activation of the complement alternative pathway in a mouse model of abdominal aortic aneurysm

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 7, 2012, Pages

  Zhou, Hui Fang ^a   Yan, Huimin ^a   Stover, Cordula M ^b   Fernandez, Tamara Montes ^c   Rodriguez De Cordoba, Santiago ^c   Song, Wen Chao ^d   Wu, Xiaobo ^a   Thompson, Robert W ^a   Schwaeble, Wilhelm J ^b   Atkinson, John P ^a   Hourcade, Dennis E ^a   Pham, Christine T N ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

^c CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALTERNATIVE COMPLEMENT PATHWAY C3 C5 CONVERTASE; ELASTASE; IMMUNOGLOBULIN G ANTIBODY; PROPERDIN;

ABDOMINAL AORTA ANEURYSM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA WALL; ARTICLE; COMPLEMENT ACTIVATION; COMPLEMENT ALTERNATIVE PATHWAY; COMPLEMENT SYSTEM; CONTROLLED STUDY; DISEASE COURSE; EMBRYO; INFLAMMATION; INNATE IMMUNITY; LOSS OF FUNCTION MUTATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING;

ANIMALS; ANTI-BACTERIAL AGENTS; AORTIC ANEURYSM, ABDOMINAL; COMPLEMENT ACTIVATION; COMPLEMENT SYSTEM PROTEINS; DISEASE MODELS, ANIMAL; MICE; PROPERDIN;

ANIMALIA; MUS;

EID: 84863135221     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1119000109     Document Type: Article

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