Coding polymorphisms in the genes of the alternative complement pathway and abdominal aortic aneurysm

International Journal of Immunogenetics

Volumn 38, Issue 3, 2011, Pages 243-248

  Bradley, D T ^a   Badger, S A ^b   Bown, M J ^c   Sayers, R D ^c   Hughes, A E ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b ROYAL GROUP OF HOSPITALS TRUST   (United Kingdom)

^c UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA;

ABDOMINAL AORTA ANEURYSM; ADULT; AGED; ARTICLE; CASE CONTROL STUDY; CAUCASIAN; COMPLEMENT SYSTEM; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENETIC POLYMORPHISM; HUMAN; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; UNITED KINGDOM;

AGED; AGED, 80 AND OVER; ALLELES; AORTIC ANEURYSM, ABDOMINAL; CASE-CONTROL STUDIES; COMPLEMENT PATHWAY, ALTERNATIVE; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 79956265707     PISSN: 17443121     EISSN: 1744313X     Source Type: Journal    
DOI: 10.1111/j.1744-313X.2011.01002.x     Document Type: Article

References (35)

1. Acosta, S., Ogren, M., Bengtsson, H., Bergqvist, D., Lindblad, B. & Zdanowski, Z. (2006) Increasing incidence of ruptured abdominal aortic aneurysm: a population-based study. Journal of Vascular Surgery, 44, 237.
2. Arapoglou, V., Kondi-Pafiti, A., Rizos, D., Kotsis, T., Kalkandis, C. & Katsenis, K. (2009) The influence of total plasma homocysteine and traditional atherosclerotic risk factors on degree of abdominal aortic aneurysm tissue inflammation. Vascular & Endovascular Surgery, 43, 473.
3. Baas, A.F., Medic, J., van 't Slot, R., de Kovel, C.G., Zhernakova, A., Geelkerken, R.H. et al. (2010) Association of the TGF-beta receptor genes with abdominal aortic aneurysm. European Journal of Human Genetics: EJHG, 18, 240.
4. Badger, S.A., Soong, C.V., O'Donnell, M.E., Mercer, C., Young, I.S. & Hughes, A.E. (2009) C-reactive protein (CRP) elevation in patients with abdominal aortic aneurysm is independent of the most important CRP genetic polymorphism. Journal of Vascular Surgery, 49, 178.
5. Bown, M.J., Lloyd, G.M., Sandford, R.M., Thompson, J.R., London, N.J.M., Samani, N.J. & Sayers, R.D. (2007) The interleukin-10-1082 'A' allele and abdominal aortic aneurysms. Journal of Vascular Surgery, 46, 687.
6. Bown, M.J., Braund, P.S., Thompson, J., London, N.J., Samani, N.J. & Sayers, R.D. (2008) Association between the coronary artery disease risk locus on chromosome 9p21.3 and abdominal aortic aneurysm. Circulation Cardiovascular Genetics, 1, 39.
7. Capella, J.F., Paik, D.C., Yin, N.X., Gervasoni, J.E. & Tilson, M.D. (1996) Complement activation and subclassification of tissue immunoglobulin G in the abdominal aortic aneurysm. The Journal of Surgical Research, 65, 31.
8. Chichester Aneurysm Screening Group, Viborg Aneurysm Screening Study, Western Australian Abdominal Aortic Aneurysm Program & Multicentre Aneurysm Screening Study (2001) A comparative study of the prevalence of abdominal aortic aneurysms in the United Kingdom, Denmark, and Australia. Journal of Medical Screening, 8, 46.
9. Clifton, M.A. (1977) Familial abdominal aortic aneurysms. The British Journal of Surgery, 64, 765.
10. Deguara, J., Burnand, K.G., Berg, J., Green, P., Lewis, C.M., Chinien, G. et al. (2007) An increased frequency of the 5A allele in the promoter region of the MMP3 gene is associated with abdominal aortic aneurysms. Human Molecular Genetics, 16, 3002.
11. Fatini, C., Pratesi, G., Sofi, F., Gensini, F., Sticchi, E., Lari, B. et al. (2005) ACE DD genotype: a predisposing factor for abdominal aortic aneurysm. European Journal of Vascular & Endovascular Surgery, 29, 227.
12. Hirose, H. & Tilson, M.D. (2001) Abdominal aortic aneurysm as an autoimmune disease. Annals of the New York Academy of Sciences, 947, 416.
13. Hughes, A.E., Orr, N., Esfandiary, H., Diaz-Torres, M., Goodship, T. & Chakravarthy, U. (2006) A common CFH haplotype, with deletion of CFHR1 and CFHR3, is associated with lower risk of age-related macular degeneration. Nature Genetics, 38, 1173.
14. Jacob, M.P. (2003) Extracellular matrix remodeling and matrix metalloproteinases in the vascular wall during aging and in pathological conditions. Biomedicine and Pharmacotherapy, 57, 195.
15. Jagadesham, V.P., Scott, D.J. & Carding, S.R. (2008) Abdominal aortic aneurysms: an autoimmune disease? Trends in molecular medicine, 14, 522.
16. Jones, G.T., Phillips, V.L., Harris, E.L., Rossaak, J.I. & van Rij, A.M. (2003) Functional matrix metalloproteinase-9 polymorphism (C-1562T) associated with abdominal aortic aneurysm. Journal of Vascular Surgery, 38, 1363.
17. Jones, G.T., Thompson, A.R., van Bockxmeer, F.M., Hafez, H., Cooper, J.A., Golledge, J., Humphries, S.E., Norman, P.E. & van Rij, A.M. (2008) Angiotensin II type 1 receptor 1166C polymorphism is associated with abdominal aortic aneurysm in three independent cohorts. Arteriosclerosis, Thrombosis & Vascular Biology, 28, 764.
18. Lindholt, J.S. & Shi, G.P. (2006) Chronic inflammation, immune response, and infection in abdominal aortic aneurysms. European Journal of Vascular & Endovascular Surgery, 31, 453.
19. Middleton, R.K., Bown, M.J., Lloyd, G.M., Jones, J.L., London, N.J. & Sayers, R.D. (2009) Characterisation of interleukin-8 and monocyte chemoattractant protein-1 expression within the abdominal aortic aneurysm and their association with mural inflammation. European Journal of Vascular & Endovascular Surgery, 37, 46.
20. Nonaka, M. & Kimura, A. (2006) Genomic view of the evolution of the complement system. Immunogenetics, 58, 701.
21. Ogata, T., Gregoire, L., Goddard, K.A.B., Skunca, M., Tromp, G., Lancaster, W.D. et al. (2006) Evidence for association between the HLA-DQA locus and abdominal aortic aneurysms in the Belgian population: a case control study. BMC Medical Genetics, 7, 67.
22. Plenge, R.M., Seielstad, M., Padyukov, L., Lee, A.T., Remmers, E.F., Ding, B. et al. (2007) TRAF1-C5 as a risk locus for rheumatoid arthritis - a genomewide study. New England Journal of Medicine, 357, 1199.
23. Purcell, S. (2009) PLINK v1.07. [Accessed on 30 October 2010].
24. Purcell, S., Neale, B., Todd-Brown, K., Thomas, L., Ferreira, M.A., Bender, D. et al. (2007) PLINK: a tool set for whole-genome association and population-based linkage analyses. American Journal of Human Genetics, 81, 559.
25. Rasmussen, T.E., Hallett Jr, J.W., Metzger, R.L., Richardson, D.M., Harmsen, W.S., Goronzy, J.J. & Weyand, C.M. (1997) Genetic risk factors in inflammatory abdominal aortic aneurysms: polymorphic residue 70 in the HLA-DR B1 gene as a key genetic element. Journal of Vascular Surgery, 25, 356.
26. Ricklin, D., Hajishengallis, G., Yang, K. & Lambris, J.D. (2010) Complement: a key system for immune surveillance and homeostasis. Nature Immunology, 11, 785.
27. Rossaak, J.I., Van Rij, A.M., Jones, G.T. & Harris, E.L. (2000) Association of the 4G/5G polymorphism in the promoter region of plasminogen activator inhibitor-1 with abdominal aortic aneurysms. Journal of Vascular Surgery, 31, 1026.
28. Sandford, B., Bown, M., London, N. & Sayers, R. (2009) The role of the CCR5 Delta32 polymorphism in abdominal aortic aneurysms. International Journal of Immunogenetics, 36, 199.
29. Tromp, G., Ogata, T., Gregoire, L., Goddard, K.A., Skunca, M., Lancaster, W.D. et al. (2006) HLA-DQA is associated with abdominal aortic aneurysms in the Belgian population. Annals of the New York Academy of Sciences, 1085, 392.
30. Vainas, T., Lubbers, T., Stassen, F.R.M., Herngreen, S.B., Van Dieijen-Visser, M.P., Bruggeman, C.A., Kitslaar, P.J.E.H.M. & Schurink, G.W.H. (2003) Serum C-reactive protein level is associated with abdominal aortic aneurysm size and may be produced by aneurysmal tissue. Circulation, 107, 1103.
31. Vammen, S., Lindholt, J.S., Ostergaard, L., Fasting, H. & Henneberg, E.W. (2001) Randomized double-blind controlled trial of roxithromycin for prevention of abdominal aortic aneurysm expansion. British Journal of Surgery, 88, 1066.
32. Wallinder, J., Bergqvist, D. & Henriksson, A.E. (2009) Proinflammatory and anti-inflammatory cytokine balance in patients with abdominal aortic aneurysm and the impact of aneurysm size. Vascular & Endovascular Surgery, 43, 258.
33. Wanhainen, A. (2008) How to define an abdominal aortic aneurysm--influence on epidemiology and clinical practice. Scandinavian Journal of Surgery: SJS: Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society, 97, 105.
34. Zipfel, P.F. & Skerka, C. (2009) Complement regulators and inhibitory proteins. Nature Reviews Immunology, 9, 729.
35. Zipfel, P.F., Heinen, S., Jozsi, M. & Skerka, C. (2006) Complement and diseases: defective alternative pathway control results in kidney and eye diseases. Molecular immunology, 43, 97.