Studies on pharmacokinetics and tissue distribution of bifendate nanosuspensions for intravenous delivery

Journal of Microencapsulation

Volumn 29, Issue 2, 2012, Pages 194-203

  Liu, Yue ^a   Zhang, Dianrui ^a   Duan, Cunxian ^a   Jia, Lejiao ^a   Xie, Pengcheng ^b   Zheng, Dandan ^a   Wang, Feihu ^a   Liu, Guangpu ^a   Hao, Leilei ^a   Zhang, Xueshun ^c   Zhang, Qiang ^d  

^a SHANDONG UNIVERSITY   (China)

^b Chemical Engineering and Technology   (China)

^c SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG UNIVERSITY   (China)

^d PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

DDB; nanosuspensions; pharmacokinetics; precipitation combined microfluidization method; tissue distribution

Indexed keywords

BIFENDATE; DIGESTIVE TRACT AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG SOLUBILITY; FREEZE DRYING; IN VITRO STUDY; IN VIVO STUDY; LASER DIFFRACTION; MALE; MICROFLUIDICS; MOUSE; NANOSUSPENSION; NONHUMAN; PARTICLE SIZE; SUSPENSION; TISSUE DISTRIBUTION; TRANSMISSION ELECTRON MICROSCOPY; X RAY DIFFRACTION;

ANIMALS; BIPHENYL COMPOUNDS; CALORIMETRY, DIFFERENTIAL SCANNING; DRUG DELIVERY SYSTEMS; DRUG STABILITY; INJECTIONS, INTRAVENOUS; MALE; MICE; MICROFLUIDIC ANALYTICAL TECHNIQUES; RABBITS; SOLUBILITY; SUSPENSIONS; TISSUE DISTRIBUTION; X-RAY DIFFRACTION;

EID: 84863115948     PISSN: 02652048     EISSN: 14645246     Source Type: Journal    
DOI: 10.3109/02652048.2011.642015     Document Type: Article

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