Ganglioside GM3 has an essential role in the pathogenesis and progression of Rheumatoid arthritis

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Tsukuda, Yukinori ^a   Iwasaki, Norimasa ^a   Seito, Naoki ^a   Kanayama, Masashi ^b   Fujitani, Naoki ^b   Shinohara, Yasuro ^b   Kasahara, Yasuhiko ^a   Onodera, Tomohiro ^a   Suzuki, Koji ^c   Asano, Tsuyoshi ^a   Minami, Akio ^a   Yamashita, Tadashi ^b,d  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

^c Hokkaido Orthopaedic Memorial Hospital   (Japan)

^d Kyungpook National University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; GAMMA INTERFERON; GANGLIOSIDE GALACTOSYLTRANSFERASE; GANGLIOSIDE GM3; INTERLEUKIN 17; INTERLEUKIN 4; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE EXACERBATION; DISEASE MODEL; ENZYME DEFICIENCY; GANGLIOSIDE GM3 SYNTHASE GENE; GENE; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; OSTEOARTHRITIS; PATHOGENESIS; RHEUMATOID ARTHRITIS; SYNOVIUM; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIBODIES; ANTIGENS, CD3; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; BIOSYNTHETIC PATHWAYS; CELL PROLIFERATION; DISEASE PROGRESSION; G(M3) GANGLIOSIDE; GENE DELETION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; IMMUNIZATION; MICE; MICE, INBRED C57BL; OSTEOARTHRITIS; PHENOTYPE; RNA, MESSENGER; SIALYLTRANSFERASES; SYNOVIAL MEMBRANE; TH17 CELLS;

EID: 84863112573     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0040136     Document Type: Article

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