Production of pyruvate in Saccharomyces cerevisiae through adaptive evolution and rational cofactor metabolic engineering

Biochemical Engineering Journal

Volumn 67, Issue , 2012, Pages 126-131

  Wang, Zhikun ^a   Gao, Cuijuan ^a   Wang, Qian ^a   Liang, Quanfeng ^a   Qi, Qingsheng ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Adaptive evolution; Cofactor metabolic engineering; Metabolic engineering; NADH NAD +; Pyruvate; Saccharomyces cerevisiae

Indexed keywords

ADAPTIVE EVOLUTION; BATCH CULTURE; CELL METABOLISM; COFACTOR ENGINEERING; COFACTORS; DIFFERENTIAL EXPRESSIONS; LACTOCOCCUS LACTIS; NADH OXIDASE; NADH/NAD +; PRODUCTION YIELD; PYRIDINE NUCLEOTIDE TRANSHYDROGENASE; PYRUVATE PRODUCTION; PYRUVATES; RECOMBINANT STRAINS; S.CEREVISIAE; SOLE CARBON SOURCE; STRAIN ENGINEERING; SYNTHETIC MEDIUM;

BATCH CELL CULTURE; CARBON; ENCODING (SYMBOLS); ESCHERICHIA COLI; ETHANOL; GLUCOSE; METABOLIC ENGINEERING; ORGANIC ACIDS; STRAIN;

YEAST;

GLUCOSE; NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) TRANSHYDROGENASE; PYRUVIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE;

ARTICLE; BIOSYNTHESIS; CELL METABOLISM; CONTROLLED STUDY; ESCHERICHIA COLI; INTRACELLULAR SPACE; LACTOCOCCUS LACTIS; METABOLIC ENGINEERING; MOLECULAR EVOLUTION; NONHUMAN; OPTICAL DENSITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SACCHAROMYCES CEREVISIAE; YEAST;

ESCHERICHIA COLI; LACTOCOCCUS LACTIS; SACCHAROMYCES CEREVISIAE;

EID: 84863109657     PISSN: 1369703X     EISSN: 1873295X     Source Type: Journal    
DOI: 10.1016/j.bej.2012.06.006     Document Type: Article

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