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Volumn 125, Issue 7, 2012, Pages 1750-1758

Deletion Of K1/K10 does not impair epidermal stratification but affects desmosomal structure and nuclear integrity

Author keywords

Cell nucleus; Desmosomes; Epidermal barrier; Epidermis; Intermediate filaments; Keratins; Knockout mice

Indexed keywords

CYTOKERATIN 1; CYTOKERATIN 10; CYTOKERATIN 14; CYTOKERATIN 5; DESMOCOLLIN; DESMOCOLLIN 1; DESMOGLEIN 1; DESMOPLAKIN; DYE; EMERIN; LAMIN A; LAMIN C; PLAKOGLOBIN; PROTEIN; SUN1 PROTEIN; UNCLASSIFIED DRUG; WATER;

EID: 84863091540     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.097139     Document Type: Article
Times cited : (66)

References (41)
  • 1
    • 3042832052 scopus 로고    scopus 로고
    • Periplakin gene targeting reveals a constituent of the cornified envelope dispensable for normal mouse development
    • Aho, S., Li, K., Ryoo, Y., McGee, C., Ishida-Yamamoto, A., Uitto, J. and Klement, J. F. (2004). Periplakin gene targeting reveals a constituent of the cornified envelope dispensable for normal mouse development. Mol. Cell. Biol. 24, 6410-6418.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 6410-6418
    • Aho, S.1    Li, K.2    Ryoo, Y.3    McGee, C.4    Ishida-Yamamoto, A.5    Uitto, J.6    Klement, J.F.7
  • 2
    • 0026356427 scopus 로고
    • Polarized and functional epithelia can form after the targeted inactivation of both mouse keratin 8 alleles
    • Baribault, H. and Oshima, R. G. (1991). Polarized and functional epithelia can form after the targeted inactivation of both mouse keratin 8 alleles. J. Cell Biol. 115, 1675-1684.
    • (1991) J. Cell Biol. , vol.115 , pp. 1675-1684
    • Baribault, H.1    Oshima, R.G.2
  • 3
    • 17144371855 scopus 로고    scopus 로고
    • The cornified envelope: a model of cell death in the skin
    • Candi, E., Schmidt, R. and Melino, G. (2005). The cornified envelope: a model of cell death in the skin. Nat. Rev. Mol. Cell Biol. 6, 328-340.
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 328-340
    • Candi, E.1    Schmidt, R.2    Melino, G.3
  • 5
    • 0027943989 scopus 로고
    • A human keratin 14 "knockout": the absence of K14 leads to severe epidermolysis bullosa simplex and a function for an intermediate filament protein
    • Chan, Y., Anton-Lamprecht, I., Yu, Q. C., Jackel, A., Zabel, B., Ernst, J. P. and Fuchs, E. (1994). A human keratin 14 "knockout": the absence of K14 leads to severe epidermolysis bullosa simplex and a function for an intermediate filament protein. Genes Dev. 8, 2574-2587.
    • (1994) Genes Dev. , vol.8 , pp. 2574-2587
    • Chan, Y.1    Anton-Lamprecht, I.2    Yu, Q.C.3    Jackel, A.4    Zabel, B.5    Ernst, J.P.6    Fuchs, E.7
  • 7
    • 79952808491 scopus 로고    scopus 로고
    • Nucleoskeleton mechanics at a glance
    • Dahl, K. N. and Kalinowski, A. (2011). Nucleoskeleton mechanics at a glance. J. Cell Sci. 124, 675-678.
    • (2011) J. Cell Sci. , vol.124 , pp. 675-678
    • Dahl, K.N.1    Kalinowski, A.2
  • 8
    • 44949118668 scopus 로고    scopus 로고
    • Nuclear shape, mechanics, and mechanotransduction
    • Dahl, K. N., Ribeiro, A. J. and Lammerding, J. (2008). Nuclear shape, mechanics, and mechanotransduction. Circ. Res. 102, 1307-1318.
    • (2008) Circ. Res. , vol.102 , pp. 1307-1318
    • Dahl, K.N.1    Ribeiro, A.J.2    Lammerding, J.3
  • 9
    • 0037128938 scopus 로고    scopus 로고
    • Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1-deficient mice
    • Furuse, M., Hata, M., Furuse, K., Yoshida, Y., Haratake, A., Sugitani, Y., Noda, T., Kubo, A. and Tsukita, S. (2002). Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1-deficient mice. J. Cell Biol. 156, 1099-1111.
    • (2002) J. Cell Biol. , vol.156 , pp. 1099-1111
    • Furuse, M.1    Hata, M.2    Furuse, K.3    Yoshida, Y.4    Haratake, A.5    Sugitani, Y.6    Noda, T.7    Kubo, A.8    Tsukita, S.9
  • 10
    • 0025154931 scopus 로고
    • Organization, structure, and polymorphisms of the human profilaggrin gene
    • Gan, S. Q., McBride, O. W., Idler, W. W., Markova, N. and Steinert, P. M. (1990). Organization, structure, and polymorphisms of the human profilaggrin gene. Biochemistry 29, 9432-9440.
    • (1990) Biochemistry , vol.29 , pp. 9432-9440
    • Gan, S.Q.1    McBride, O.W.2    Idler, W.W.3    Markova, N.4    Steinert, P.M.5
  • 11
    • 39849097562 scopus 로고    scopus 로고
    • Desmosome structure, composition and function
    • Garrod, D. and Chidgey, M. (2008). Desmosome structure, composition and function. Biochim. Biophys. Acta 1778, 572-587.
    • (2008) Biochim. Biophys. Acta , vol.1778 , pp. 572-587
    • Garrod, D.1    Chidgey, M.2
  • 13
    • 0031865846 scopus 로고    scopus 로고
    • Patterned acquisition of skin barrier function during development
    • Hardman, M. J., Sisi, P., Banbury, D. N. and Byrne, C. (1998). Patterned acquisition of skin barrier function during development. Development 125, 1541-1552.
    • (1998) Development , vol.125 , pp. 1541-1552
    • Hardman, M.J.1    Sisi, P.2    Banbury, D.N.3    Byrne, C.4
  • 14
    • 68849112456 scopus 로고    scopus 로고
    • Intermediate filaments: primary determinants of cell architecture and plasticity
    • Herrmann, H., Strelkov, S. V., Burkhard, P. and Aebi, U. (2009). Intermediate filaments: primary determinants of cell architecture and plasticity. J. Clin. Invest. 119, 1772-1783.
    • (2009) J. Clin. Invest. , vol.119 , pp. 1772-1783
    • Herrmann, H.1    Strelkov, S.V.2    Burkhard, P.3    Aebi, U.4
  • 15
    • 0027535762 scopus 로고
    • Mouse differentiation-specific keratins 1 and 10 require a preexisting keratin scaffold to form a filament network
    • Kartasova, T., Roop, D. R., Holbrook, K. A. and Yuspa, S. H. (1993). Mouse differentiation-specific keratins 1 and 10 require a preexisting keratin scaffold to form a filament network. J. Cell Biol. 120, 1251-1261.
    • (1993) J. Cell Biol. , vol.120 , pp. 1251-1261
    • Kartasova, T.1    Roop, D.R.2    Holbrook, K.A.3    Yuspa, S.H.4
  • 16
    • 35648937494 scopus 로고    scopus 로고
    • Requirements for the localization of nesprin-3 at the nuclear envelope and its interaction with plectin
    • Ketema, M., Wilhelmsen, K., Kuikman, I., Janssen, H., Hodzic, D. and Sonnenberg, A. (2007). Requirements for the localization of nesprin-3 at the nuclear envelope and its interaction with plectin. J. Cell Sci. 120, 3384-3394.
    • (2007) J. Cell Sci. , vol.120 , pp. 3384-3394
    • Ketema, M.1    Wilhelmsen, K.2    Kuikman, I.3    Janssen, H.4    Hodzic, D.5    Sonnenberg, A.6
  • 17
    • 0037275640 scopus 로고    scopus 로고
    • Keratins: a structural scaffold with emerging functions
    • Kirfel, J., Magin, T. M. and Reichelt, J. (2003). Keratins: a structural scaffold with emerging functions. Cell. Mol. Life Sci. 60, 56-71.
    • (2003) Cell. Mol. Life Sci. , vol.60 , pp. 56-71
    • Kirfel, J.1    Magin, T.M.2    Reichelt, J.3
  • 18
    • 0034675890 scopus 로고    scopus 로고
    • Lessons from loricrin-deficient mice: compensatory mechanisms maintaining skin barrier function in the absence of a major cornified envelope protein
    • Koch, P. J., de Viragh, P. A., Scharer, E., Bundman, D., Longley, M. A., Bickenbach, J., Kawachi, Y., Suga, Y., Zhou, Z., Huber, M. et al. (2000). Lessons from loricrin-deficient mice: compensatory mechanisms maintaining skin barrier function in the absence of a major cornified envelope protein. J. Cell Biol. 151, 389-400.
    • (2000) J. Cell Biol. , vol.151 , pp. 389-400
    • Koch, P.J.1    de Viragh, P.A.2    Scharer, E.3    Bundman, D.4    Longley, M.A.5    Bickenbach, J.6    Kawachi, Y.7    Suga, Y.8    Zhou, Z.9    Huber, M.10
  • 19
    • 69549096268 scopus 로고    scopus 로고
    • Corneodesmosin gene ablation induces lethal skin-barrier disruption and hair-follicle degeneration related to desmosome dysfunction
    • Leclerc, E. A., Huchenq, A., Mattiuzzo, N. R., Metzger, D., Chambon, P., Ghyselinck, N. B., Serre, G., Jonca, N. and Guerrin, M. (2009). Corneodesmosin gene ablation induces lethal skin-barrier disruption and hair-follicle degeneration related to desmosome dysfunction. J. Cell Sci. 122, 2699-2709.
    • (2009) J. Cell Sci. , vol.122 , pp. 2699-2709
    • Leclerc, E.A.1    Huchenq, A.2    Mattiuzzo, N.R.3    Metzger, D.4    Chambon, P.5    Ghyselinck, N.B.6    Serre, G.7    Jonca, N.8    Guerrin, M.9
  • 20
    • 13544264752 scopus 로고    scopus 로고
    • MAN1, an integral protein of the inner nuclear membrane, binds Smad2 and Smad3 and antagonizes transforming growth factor-beta signaling
    • Lin, F., Morrison, J. M., Wu, W. and Worman, H. J. (2005). MAN1, an integral protein of the inner nuclear membrane, binds Smad2 and Smad3 and antagonizes transforming growth factor-beta signaling. Hum. Mol. Genet. 14, 437-445.
    • (2005) Hum. Mol. Genet. , vol.14 , pp. 437-445
    • Lin, F.1    Morrison, J.M.2    Wu, W.3    Worman, H.J.4
  • 21
    • 0029043889 scopus 로고
    • The basal keratin network of stratified squamous epithelia: defining K15 function in the absence of K14
    • Lloyd, C., Yu, Q. C., Cheng, J., Turksen, K., Degenstein, L., Hutton, E. and Fuchs, E. (1995). The basal keratin network of stratified squamous epithelia: defining K15 function in the absence of K14. J. Cell Biol. 129, 1329-1344.
    • (1995) J. Cell Biol. , vol.129 , pp. 1329-1344
    • Lloyd, C.1    Yu, Q.C.2    Cheng, J.3    Turksen, K.4    Degenstein, L.5    Hutton, E.6    Fuchs, E.7
  • 22
    • 2642684550 scopus 로고    scopus 로고
    • Lessons from keratin 18 knockout mice: formation of novel keratin filaments, secondary loss of keratin 7 and accumulation of liver-specific keratin 8-positive aggregates
    • Magin, T. M., Schroder, R., Leitgeb, S., Wanninger, F., Zatloukal, K., Grund, C. and Melton, D. W. (1998). Lessons from keratin 18 knockout mice: formation of novel keratin filaments, secondary loss of keratin 7 and accumulation of liver-specific keratin 8-positive aggregates. J. Cell Biol. 140, 1441-1451.
    • (1998) J. Cell Biol. , vol.140 , pp. 1441-1451
    • Magin, T.M.1    Schroder, R.2    Leitgeb, S.3    Wanninger, F.4    Zatloukal, K.5    Grund, C.6    Melton, D.W.7
  • 23
    • 14244257660 scopus 로고    scopus 로고
    • Developing mouse models to study intermediate filament function
    • Magin, T. M., Hesse, M., Meier-Bornheim, R. and Reichelt, J. (2004). Developing mouse models to study intermediate filament function. Methods Cell Biol. 78, 65-94.
    • (2004) Methods Cell Biol , vol.78 , pp. 65-94
    • Magin, T.M.1    Hesse, M.2    Meier-Bornheim, R.3    Reichelt, J.4
  • 25
    • 0029738727 scopus 로고    scopus 로고
    • Disruption of muscle architecture and myocardial degeneration in mice lacking desmin
    • Milner, D. J., Weitzer, G., Tran, D., Bradley, A. and Capetanaki, Y. (1996). Disruption of muscle architecture and myocardial degeneration in mice lacking desmin. J. Cell Biol. 134, 1255-1270.
    • (1996) J. Cell Biol. , vol.134 , pp. 1255-1270
    • Milner, D.J.1    Weitzer, G.2    Tran, D.3    Bradley, A.4    Capetanaki, Y.5
  • 26
    • 44149099717 scopus 로고    scopus 로고
    • The human keratins: biology and pathology
    • Moll, R., Divo, M. and Langbein, L. (2008). The human keratins: biology and pathology. Histochem. Cell Biol. 129, 705-733.
    • (2008) Histochem. Cell Biol. , vol.129 , pp. 705-733
    • Moll, R.1    Divo, M.2    Langbein, L.3
  • 27
    • 0035158066 scopus 로고    scopus 로고
    • Complete cytolysis and neonatal lethality in keratin 5 knockout mice reveal its fundamental role in skin integrity and in epidermolysis bullosa simplex
    • Peters, B., Kirfel, J., Bussow, H., Vidal, M. and Magin, T. M. (2001). Complete cytolysis and neonatal lethality in keratin 5 knockout mice reveal its fundamental role in skin integrity and in epidermolysis bullosa simplex. Mol. Biol. Cell 12, 1775-1789.
    • (2001) Mol. Biol. Cell , vol.12 , pp. 1775-1789
    • Peters, B.1    Kirfel, J.2    Bussow, H.3    Vidal, M.4    Magin, T.M.5
  • 28
    • 79952780707 scopus 로고    scopus 로고
    • Nesprin-3 augments peripheral nuclear localization of intermediate filaments in zebrafish
    • Postel, R., Ketema, M., Kuikman, I., de Pereda, J. M. and Sonnenberg, A. (2010). Nesprin-3 augments peripheral nuclear localization of intermediate filaments in zebrafish. J. Cell Sci. 124, 755-764.
    • (2010) J. Cell Sci. , vol.124 , pp. 755-764
    • Postel, R.1    Ketema, M.2    Kuikman, I.3    de Pereda, J.M.4    Sonnenberg, A.5
  • 29
    • 0035499865 scopus 로고    scopus 로고
    • Regulated expression of human filaggrin in keratinocytes results in cytoskeletal disruption, loss of cell-cell adhesion, and cell cycle arrest
    • Presland, R. B., Kuechle, M. K., Lewis, S. P., Fleckman, P. and Dale, B. A. (2001). Regulated expression of human filaggrin in keratinocytes results in cytoskeletal disruption, loss of cell-cell adhesion, and cell cycle arrest. Exp. Cell Res. 270, 199-213.
    • (2001) Exp. Cell Res. , vol.270 , pp. 199-213
    • Presland, R.B.1    Kuechle, M.K.2    Lewis, S.P.3    Fleckman, P.4    Dale, B.A.5
  • 30
    • 69449090753 scopus 로고    scopus 로고
    • Bringin KASH under the SUN: the many faces of nucleo-cytoskeletal connections
    • Razafsky, D. and Hodzic, D. (2009). Bringing KASH under the SUN: the many faces of nucleo-cytoskeletal connections. J. Cell Biol. 186, 461-472.
    • (2009) J. Cell Biol. , vol.186 , pp. 461-472
    • Razafsky, D.1    Hodzic, D.2
  • 31
    • 0036629336 scopus 로고    scopus 로고
    • Hyperproliferation, induction of c-Myc and 14-3-3sigma, but no cell fragility in keratin-10-null mice
    • Reichelt, J. and Magin, T. M. (2002). Hyperproliferation, induction of c-Myc and 14-3-3sigma, but no cell fragility in keratin-10-null mice. J. Cell Sci. 115, 2639-2650.
    • (2002) J. Cell Sci. , vol.115 , pp. 2639-2650
    • Reichelt, J.1    Magin, T.M.2
  • 32
    • 0030817021 scopus 로고    scopus 로고
    • Out of balance: consequences of a partial keratin 10 knockout
    • Reichelt, J., Bauer, C., Porter, R., Lane, E. and Magin, T. M. (1997). Out of balance: consequences of a partial keratin 10 knockout. J. Cell Sci. 110, 2175-2186.
    • (1997) J. Cell Sci. , vol.110 , pp. 2175-2186
    • Reichelt, J.1    Bauer, C.2    Porter, R.3    Lane, E.4    Magin, T.M.5
  • 33
    • 0032835593 scopus 로고    scopus 로고
    • Normal ultrastructure, but altered stratum corneum lipid and protein composition in a mouse model for epidermolytic hyperkeratosis
    • Reichelt, J., Doering, T., Schnetz, E., Fartasch, M., Sandhoff, K. and Magin, T. M. (1999). Normal ultrastructure, but altered stratum corneum lipid and protein composition in a mouse model for epidermolytic hyperkeratosis. J. Invest. Dermatol. 113, 329-334.
    • (1999) J. Invest. Dermatol. , vol.113 , pp. 329-334
    • Reichelt, J.1    Doering, T.2    Schnetz, E.3    Fartasch, M.4    Sandhoff, K.5    Magin, T.M.6
  • 34
    • 0035163065 scopus 로고    scopus 로고
    • Formation of a normal epidermis supported by increased stability of keratins 5 and 14 in keratin 10 null mice
    • Reichelt, J., Bussow, H., Grund, C. and Magin, T. M. (2001). Formation of a normal epidermis supported by increased stability of keratins 5 and 14 in keratin 10 null mice. Mol. Biol. Cell 12, 1557-1568.
    • (2001) Mol. Biol. Cell , vol.12 , pp. 1557-1568
    • Reichelt, J.1    Bussow, H.2    Grund, C.3    Magin, T.M.4
  • 35
    • 0023503613 scopus 로고
    • An unusual type-II 70-kilodalton keratin protein of mouse epidermis exhibiting postnatal bodysite specificity and sensitivity to hyperproliferation
    • Rentrop, M., Nischt, R., Knapp, B., Schweizer, J. and Winter, H. (1987). An unusual type-II 70-kilodalton keratin protein of mouse epidermis exhibiting postnatal bodysite specificity and sensitivity to hyperproliferation. Differentiation 34, 189-200.
    • (1987) Differentiation , vol.34 , pp. 189-200
    • Rentrop, M.1    Nischt, R.2    Knapp, B.3    Schweizer, J.4    Winter, H.5
  • 38
    • 36749031152 scopus 로고    scopus 로고
    • Blurring the boundary: the nuclear envelope extends its reach
    • Stewart, C. L., Roux, K. J. and Burke, B. (2007). Blurring the boundary: the nuclear envelope extends its reach. Science 318, 1408-1412.
    • (2007) Science , vol.318 , pp. 1408-1412
    • Stewart, C.L.1    Roux, K.J.2    Burke, B.3
  • 40
    • 34249792742 scopus 로고    scopus 로고
    • Keratin transgenic and knockout mice: functional analysis and validation of disease-causing mutations
    • Vijayaraj, P., Sohl, G. and Magin, T. M. (2007). Keratin transgenic and knockout mice: functional analysis and validation of disease-causing mutations. Methods Mol. Biol. 360, 203-251.
    • (2007) Methods Mol. Biol. , vol.360 , pp. 203-251
    • Vijayaraj, P.1    Sohl, G.2    Magin, T.M.3


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