Sex differences in the response to viral infections: TLR8 and TLR9 ligand stimulation induce higher IL10 production in males

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Torcia, Maria Gabriella ^a   Nencioni, Lucia ^b   Clemente, Ann Maria ^a   Civitelli, Livia ^b   Celestino, Ignacio ^b   Limongi, Dolores ^c   Fadigati, Giulia ^a   Perissi, Eloisa ^a   Cozzolino, Federico ^a   Garaci, Enrico ^c   Palamara, Anna Teresa ^b,d  

^a UNIVERSITY OF FLORENCE   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

^d IRCCS SAN RAFFAELE PISANA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; ESTRADIOL; HYDROCORTISONE; INTERLEUKIN 10; LIGAND; PRASTERONE; TESTOSTERONE; TOLL LIKE RECEPTOR 3 LIGAND; TOLL LIKE RECEPTOR 7 LIGAND; TOLL LIKE RECEPTOR 8 LIGAND; TOLL LIKE RECEPTOR 9 LIGAND; UNCLASSIFIED DRUG; VIRUS RNA;

ADAPTIVE IMMUNITY; ADULT; AGED; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE PREDISPOSITION; FEMALE; HERPES SIMPLEX; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INFLUENZA; INFLUENZA VIRUS A H1N1; INNATE IMMUNITY; MALE; NEUROMODULATION; NONHUMAN; NORMAL HUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; SEX DIFFERENCE; VIRUS INFECTION;

ADULT; FEMALE; GONADAL STEROID HORMONES; HEK293 CELLS; HERPESVIRUS 1, HUMAN; HUMANS; INFLUENZA A VIRUS; INTERFERON-ALPHA; INTERLEUKIN-10; INTERLEUKIN-12; INTERLEUKIN-13; LEUKOCYTES, MONONUCLEAR; LIGANDS; MALE; MIDDLE AGED; NUCLEIC ACIDS; SEX CHARACTERISTICS; TOLL-LIKE RECEPTOR 8; TOLL-LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR-ALPHA; VIRUS DISEASES;

HERPES; HUMAN HERPESVIRUS 1;

EID: 84863090280     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0039853     Document Type: Article

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