The gain-of-function variant allele CYP2C19*17: A double-edged sword between thrombosis and bleeding in clopidogrel-treated patients

Journal of Thrombosis and Haemostasis

Volumn 10, Issue 2, 2012, Pages 199-206

  Li, Y ^a,b   Tang, H L ^a   Hu, Y F ^a   Xie, H G ^c  

^a PEKING UNIVERSITY THIRD HOSPITAL   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^c NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Bleeding; Clopidogrel; CYP2C19*17 polymorphism; Major adverse cardiovascular events; Meta analysis; Platelet

Indexed keywords

CLOPIDOGREL; CYTOCHROME P450 2C19;

ARTICLE; BLEEDING; CAUSE OF DEATH; CLINICAL STUDY; CORONARY ARTERY DISEASE; GAIN OF FUNCTION MUTATION; GENETIC VARIABILITY; HEART INFARCTION; HETEROZYGOTE; HUMAN; META ANALYSIS; MORTALITY; PREVALENCE; PRIORITY JOURNAL; RECURRENT DISEASE; REVASCULARIZATION; RISK FACTOR; STENT THROMBOSIS; STROKE; THROMBOSIS; TREATMENT RESPONSE;

ARYL HYDROCARBON HYDROXYLASES; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; HEMORRHAGE; HUMANS; ODDS RATIO; PHENOTYPE; PLATELET AGGREGATION INHIBITORS; RISK ASSESSMENT; RISK FACTORS; THROMBOSIS; TICLOPIDINE; TREATMENT OUTCOME;

EID: 84863082704     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2011.04570.x     Document Type: Article

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