Epidermal growth factor receptor signaling mediates vesicant-induced airway epithelial secretion of interleukin-6 and production of mucin

American Journal of Respiratory Cell and Molecular Biology

Volumn 46, Issue 2, 2012, Pages 157-164

  Karacsonyi, Claudia ^a   Lee, Ji Hyeon ^a   Shanmugam, Naga ^a   Kagan, Elliott ^a  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

Epidermal growth factor receptor; Interleukin 6; MUC5AC; Nitrogen mustard; Vesicants

Indexed keywords

4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; BLOCKING ANTIBODY; CHLORMETHINE; EPIDERMAL GROWTH FACTOR RECEPTOR; ILOMASTAT; INTERLEUKIN 6; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MUCIN; MUCIN 5AC; MUSTARD GAS; TRANSFORMING GROWTH FACTOR ALPHA;

ARTICLE; CELL STRUCTURE; CONTROLLED STUDY; CYTOKINE RELEASE; EPITHELIUM CELL; HUMAN; HUMAN CELL; LYSOSOME; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; RECEPTOR UPREGULATION; RESPIRATORY EPITHELIUM; SIGNAL TRANSDUCTION; UBIQUITINATION;

BLOTTING, WESTERN; CELLS, CULTURED; ENZYME ACTIVATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; INTERLEUKIN-6; MITOGEN-ACTIVATED PROTEIN KINASES; MUCINS; PHOSPHORYLATION; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; TRACHEA;

EID: 84863062611     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2010-0440OC     Document Type: Article

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