Structural aspects of M3 muscarinic acetylcholine receptor dimer formation and activation

FASEB Journal

Volumn 26, Issue 2, 2012, Pages 604-616

  Hu, Jianxin ^a   Thor, Doreen ^a   Zhou, Yaru ^a,b   Liu, Tong ^a   Wang, Yan ^a   McMillin, Sara M ^a   Mistry, Rajendra ^c   Challiss, R A John ^c   Costanzi, Stefano ^a   Wess, Jürgen ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b HEBEI MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Disulfidescanning mutagenesis; G protein coupled receptor; GPCR

Indexed keywords

CARBACHOL; CYSTEINE; DIMER; DISULFIDE; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; MUSCARINIC M3 RECEPTOR;

AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; CROSS LINKING; IMMUNOPRECIPITATION; MOLECULAR MECHANICS; MOLECULAR MODEL; MUTANT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; STRUCTURAL HOMOLOGY; SUBSTITUTION REACTION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; BINDING SITES; CERCOPITHECUS AETHIOPS; COS CELLS; CROSS-LINKING REAGENTS; DIMERIZATION; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTANT PROTEINS; PROTEIN STRUCTURE, QUATERNARY; RATS; RECEPTOR, MUSCARINIC M3; RECOMBINANT PROTEINS;

RATTUS;

EID: 84863045698     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-191510     Document Type: Article

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