Taxol, a microtubule stabilizer, improves cardiac functional recovery during postischemic reperfusion in rat in vitro

Cardiovascular Therapeutics

Volumn 30, Issue 1, 2012, Pages 12-30

  Xiao, Junjie ^a,b   Liang, Dandan ^b   Liu, Ying ^a,b   Zhang, Hong ^a,b   Liu, Yi ^b   Zhao, Hong ^b   Li, Jun ^b   Peng, Luying ^b   Zhou, Zhaonian ^c   Chen, Yi Han ^a,b  

^a TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

^b TONGJI UNIVERSITY   (China)

^c Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

Author keywords

Arrhythmias; Calcium overload; Microtubule; Mitochondrial permeability transition pore; Postischemia reperfusion; Taxol

Indexed keywords

CALCIUM; CYTOCHROME C; FLUO 3; FURA 2; MESSENGER RNA; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; PACLITAXEL; PHOSPHOLAMBAN; PHOSPHOSERINE; PHOSPHOTHREONINE; REACTIVE OXYGEN METABOLITE; RYANODINE RECEPTOR; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE 2; TRIPHENYLTETRAZOLIUM; UNCLASSIFIED DRUG;

AFTERDISCHARGE; AMPLITUDE MODULATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL DEATH; CONTROLLED STUDY; CONVALESCENCE; CYTOSOL; DISEASE SEVERITY; DRUG EFFECT; ENZYME ACTIVITY; FLUOROMETRY; GENE EXPRESSION; HEART FUNCTION; HEART LEFT VENTRICLE; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART MUSCLE ISCHEMIA; HEART MUSCLE REFRACTORY PERIOD; HEART MUSCLE REPERFUSION; HEART VENTRICLE ARRHYTHMIA; IMMUNOHISTOCHEMISTRY; ISOLATED HEART; MALE; MICROELECTRODE; MICROTUBULE; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REPERFUSION INJURY; SARCOPLASMIC RETICULUM; SPECTROPHOTOMETRY; WESTERN BLOTTING;

ACTION POTENTIALS; ANIMALS; APOPTOSIS; ARRHYTHMIAS, CARDIAC; CALCIUM SIGNALING; CALCIUM-BINDING PROTEINS; CYTOCHROMES C; DOSE-RESPONSE RELATIONSHIP, DRUG; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICROTUBULES; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MYOCARDIAL CONTRACTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; NECROSIS; OXIDATIVE STRESS; PACLITAXEL; PERFUSION; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RECOVERY OF FUNCTION; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; TIME FACTORS; TUBULIN MODULATORS; VENTRICULAR FUNCTION, LEFT; VENTRICULAR PRESSURE;

EID: 84863038697     PISSN: 17555914     EISSN: 17555922     Source Type: Journal    
DOI: 10.1111/j.1755-5922.2010.00163.x     Document Type: Article

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