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Volumn 27, Issue SUPPL.2, 2012, Pages 94-98

Morphogens and hepatic stellate cell fate regulation in chronic liver disease

Author keywords

Necdin; Ppar ; Shh; Wnt

Indexed keywords

BETA CATENIN; COLLAGEN; COLLAGEN TYPE 1; COLLAGEN TYPE 4; DICKKOPF 1 PROTEIN; GAMMA SECRETASE; LEPTIN; MATRIX METALLOPROTEINASE INHIBITOR; METALLOPROTEINASE INHIBITOR; MONOCYTE CHEMOTACTIC PROTEIN 1; MORPHOGEN; NECDIN; NOTCH RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PLATELET DERIVED GROWTH FACTOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE; SONIC HEDGEHOG PROTEIN; TOLL LIKE RECEPTOR; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; WNT PROTEIN;

EID: 84863023178     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2011.07022.x     Document Type: Article
Times cited : (35)

References (46)
  • 2
    • 84895614837 scopus 로고
    • Uber den EingluB der Insulin-Traubenzucker-Injektion auf die "Fettspeicherungsellen" der Leber
    • Kano K etal. Uber den EingluB der Insulin-Traubenzucker-Injektion auf die "Fettspeicherungsellen" der Leber. Arch. Histol. Jpn. 1952; 4: 13-24.
    • (1952) Arch. Histol. Jpn. , vol.4 , pp. 13-24
    • Kano, K.1
  • 3
    • 85007934176 scopus 로고
    • Uber den EinfluB der Insulin-Traubenzucker-Injektion auf die "Fettspeicherungsellen" der Leber
    • Sunaga Y. Uber den EinfluB der Insulin-Traubenzucker-Injektion auf die "Fettspeicherungsellen" der Leber. Arch. Histol. Jpn. 1954; 7: 241-9.
    • (1954) Arch. Histol. Jpn. , vol.7 , pp. 241-249
    • Sunaga, Y.1
  • 4
    • 84895660255 scopus 로고
    • Studies on the "fat-storing cells" (Fettspeicherungszellen) in the liver
    • Ito T etal. Studies on the "fat-storing cells" (Fettspeicherungszellen) in the liver. Arch. Anat. Nippon. 1956; 31: 10-15.
    • (1956) Arch. Anat. Nippon. , vol.31 , pp. 10-15
    • Ito, T.1
  • 5
    • 35948954244 scopus 로고    scopus 로고
    • Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver
    • Friedman SL. Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver. Physiol. Rev. 2008; 88: 125-72.
    • (2008) Physiol. Rev. , vol.88 , pp. 125-172
    • Friedman, S.L.1
  • 7
    • 0034808310 scopus 로고    scopus 로고
    • History, heterogeneity, developmental biology, and functions of quiescent hepatic stellate cells
    • Geerts A. History, heterogeneity, developmental biology, and functions of quiescent hepatic stellate cells. Semin. Liver Dis. 2001; 21: 311-35.
    • (2001) Semin. Liver Dis. , vol.21 , pp. 311-335
    • Geerts, A.1
  • 8
    • 63349109309 scopus 로고    scopus 로고
    • Mesenchymal origin of hepatic stellate cells, submesothelial cells, and perivascular mesenchymal cells during mouse liver development
    • Asahina K, Tsai SY, Li P etal. Mesenchymal origin of hepatic stellate cells, submesothelial cells, and perivascular mesenchymal cells during mouse liver development. Hepatology 2009; 49: 998-1011.
    • (2009) Hepatology , vol.49 , pp. 998-1011
    • Asahina, K.1    Tsai, S.Y.2    Li, P.3
  • 9
    • 79952240154 scopus 로고    scopus 로고
    • Septum transversum-derived mesothelium gives rise to hepatic stellate cells and perivascular mesenchymal cells in developing mouse liver
    • Asahina K, Zhou B, Pu WT, Tsukamoto H. Septum transversum-derived mesothelium gives rise to hepatic stellate cells and perivascular mesenchymal cells in developing mouse liver. Hepatology 2011; 53: 983-95.
    • (2011) Hepatology , vol.53 , pp. 983-995
    • Asahina, K.1    Zhou, B.2    Pu, W.T.3    Tsukamoto, H.4
  • 10
    • 0032489223 scopus 로고    scopus 로고
    • Transdifferentiation of rat hepatic stellate cells results in leptin expression
    • Potter JJ, Womack L, Mezey E, Anania FA. Transdifferentiation of rat hepatic stellate cells results in leptin expression. Biochem. Biophys. Res. Commun. 1998; 244: 178-82.
    • (1998) Biochem. Biophys. Res. Commun. , vol.244 , pp. 178-182
    • Potter, J.J.1    Womack, L.2    Mezey, E.3    Anania, F.A.4
  • 11
    • 36349011366 scopus 로고    scopus 로고
    • Acetaldehyde increases endogenous adiponectin and fibrogenesis in hepatic stellate cells but exogenous adiponectin inhibits fibrogenesis
    • Potter JJ, Mezey E. Acetaldehyde increases endogenous adiponectin and fibrogenesis in hepatic stellate cells but exogenous adiponectin inhibits fibrogenesis. Alcohol. Clin. Exp. Res. 2007; 31: 2092-100.
    • (2007) Alcohol. Clin. Exp. Res. , vol.31 , pp. 2092-2100
    • Potter, J.J.1    Mezey, E.2
  • 12
    • 14244257340 scopus 로고    scopus 로고
    • Adipogenic transcriptional regulation of hepatic stellate cells
    • She H, Xiong S, Hazra S, Tsukamoto H. Adipogenic transcriptional regulation of hepatic stellate cells. J. Biol. Chem. 2005; 280: 4959-67.
    • (2005) J. Biol. Chem. , vol.280 , pp. 4959-4967
    • She, H.1    Xiong, S.2    Hazra, S.3    Tsukamoto, H.4
  • 13
    • 0034680787 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors and hepatic stellate cell activation
    • Miyahara T, Schrum L, Rippe R etal. Peroxisome proliferator-activated receptors and hepatic stellate cell activation. J. Biol. Chem. 2000; 275: 35715-22.
    • (2000) J. Biol. Chem. , vol.275 , pp. 35715-35722
    • Miyahara, T.1    Schrum, L.2    Rippe, R.3
  • 14
    • 0030297919 scopus 로고    scopus 로고
    • Adipogenesis and obesity: rounding out the big picture
    • Spiegelman BM, Flier JS. Adipogenesis and obesity: rounding out the big picture. Cell 1996; 87: 377-89.
    • (1996) Cell , vol.87 , pp. 377-389
    • Spiegelman, B.M.1    Flier, J.S.2
  • 15
    • 1642524221 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma induces a phenotypic switch from activated to quiescent hepatic stellate cells
    • Hazra S, Xiong S, Wang J etal. Peroxisome proliferator-activated receptor gamma induces a phenotypic switch from activated to quiescent hepatic stellate cells. J. Biol. Chem. 2004; 279: 11392-401.
    • (2004) J. Biol. Chem. , vol.279 , pp. 11392-11401
    • Hazra, S.1    Xiong, S.2    Wang, J.3
  • 16
    • 28844502262 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma suppresses proximal alpha1(I) collagen promoter via inhibition of p300-facilitated NF-I binding to DNA in hepatic stellate cells
    • Yavrom S, Chen L, Xiong S, Wang J, Rippe RA, Tsukamoto H. Peroxisome proliferator-activated receptor gamma suppresses proximal alpha1(I) collagen promoter via inhibition of p300-facilitated NF-I binding to DNA in hepatic stellate cells. J. Biol. Chem. 2005; 280: 40650-9.
    • (2005) J. Biol. Chem. , vol.280 , pp. 40650-40659
    • Yavrom, S.1    Chen, L.2    Xiong, S.3    Wang, J.4    Rippe, R.A.5    Tsukamoto, H.6
  • 17
    • 0033855572 scopus 로고    scopus 로고
    • Ligands of peroxisome proliferator-activated receptor gamma modulate profibrogenic and proinflammatory actions in hepatic stellate cells
    • Marra F, Efsen E, Romanelli RG etal. Ligands of peroxisome proliferator-activated receptor gamma modulate profibrogenic and proinflammatory actions in hepatic stellate cells. Gastroenterology 2000; 119: 466-78.
    • (2000) Gastroenterology , vol.119 , pp. 466-478
    • Marra, F.1    Efsen, E.2    Romanelli, R.G.3
  • 18
    • 0036082703 scopus 로고    scopus 로고
    • Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro
    • Galli A, Crabb DW, Ceni E etal. Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro. Gastroenterology 2002; 122: 1924-40.
    • (2002) Gastroenterology , vol.122 , pp. 1924-1940
    • Galli, A.1    Crabb, D.W.2    Ceni, E.3
  • 19
    • 44949226873 scopus 로고    scopus 로고
    • Tumour-stroma interactions in colorectal cancer: converging on β-catenin activation and cancer stemness
    • Le NH, Franken P, Fodde R. Tumour-stroma interactions in colorectal cancer: converging on β-catenin activation and cancer stemness. Br. J. Cancer 2008; 98: 1886-93.
    • (2008) Br. J. Cancer , vol.98 , pp. 1886-1893
    • Le, N.H.1    Franken, P.2    Fodde, R.3
  • 21
    • 0037163113 scopus 로고    scopus 로고
    • Regulation of Wnt signaling during adipogenesis
    • Bennett CN, Ross SE, Longo KA etal. Regulation of Wnt signaling during adipogenesis. J. Biol. Chem. 2002; 277: 30998-1004.
    • (2002) J. Biol. Chem. , vol.277 , pp. 30998-31004
    • Bennett, C.N.1    Ross, S.E.2    Longo, K.A.3
  • 22
    • 0034637103 scopus 로고    scopus 로고
    • Inhibition of adipogenesis by Wnt signaling
    • Ross SE, Hemati N, Longo KA etal. Inhibition of adipogenesis by Wnt signaling. Science 2000; 289: 950-3.
    • (2000) Science , vol.289 , pp. 950-953
    • Ross, S.E.1    Hemati, N.2    Longo, K.A.3
  • 24
    • 20444417035 scopus 로고    scopus 로고
    • Prediction of preadipocyte differentiation by gene expression reveals role of insulin receptor substrates and necdin
    • Tseng YH, Butte AJ, Kokkotou E etal. Prediction of preadipocyte differentiation by gene expression reveals role of insulin receptor substrates and necdin. Nat. Cell Biol. 2005; 7: 601-11.
    • (2005) Nat. Cell Biol. , vol.7 , pp. 601-611
    • Tseng, Y.H.1    Butte, A.J.2    Kokkotou, E.3
  • 25
    • 33744996959 scopus 로고    scopus 로고
    • Necdin promotes GABAergic neuron differentiation in cooperation with Dlx homeodomain proteins
    • Kuwajima T, Nishimura I, Yoshikawa K. Necdin promotes GABAergic neuron differentiation in cooperation with Dlx homeodomain proteins. J. Neurosci. 2006; 26: 5383-92.
    • (2006) J. Neurosci. , vol.26 , pp. 5383-5392
    • Kuwajima, T.1    Nishimura, I.2    Yoshikawa, K.3
  • 26
    • 4644369736 scopus 로고    scopus 로고
    • Necdin interacts with the Msx2 homeodomain protein via MAGE-D1 to promote myogenic differentiation of C2C12 cells
    • Kuwajima T, Taniura H, Nishimura I, Yoshikawa K. Necdin interacts with the Msx2 homeodomain protein via MAGE-D1 to promote myogenic differentiation of C2C12 cells. J. Biol. Chem. 2004; 279: 40484-93.
    • (2004) J. Biol. Chem. , vol.279 , pp. 40484-40493
    • Kuwajima, T.1    Taniura, H.2    Nishimura, I.3    Yoshikawa, K.4
  • 27
    • 3042784665 scopus 로고    scopus 로고
    • Msx2 and necdin combined activities are required for smooth muscle differentiation in mesoangioblast stem cells
    • Brunelli S, Tagliafico E, De Angelis FG etal. Msx2 and necdin combined activities are required for smooth muscle differentiation in mesoangioblast stem cells. Circ. Res. 2004; 94: 1571-8.
    • (2004) Circ. Res. , vol.94 , pp. 1571-1578
    • Brunelli, S.1    Tagliafico, E.2    De Angelis, F.G.3
  • 28
    • 77957280791 scopus 로고    scopus 로고
    • The necdin-Wnt pathway causes epigenetic peroxisome proliferator-activated receptor gamma repression in hepatic stellate cells
    • Zhu NL, Wang J, Tsukamoto H. The necdin-Wnt pathway causes epigenetic peroxisome proliferator-activated receptor gamma repression in hepatic stellate cells. J. Biol. Chem. 2010; 285: 30463-71.
    • (2010) J. Biol. Chem. , vol.285 , pp. 30463-30471
    • Zhu, N.L.1    Wang, J.2    Tsukamoto, H.3
  • 29
    • 75149141045 scopus 로고    scopus 로고
    • MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis
    • Mann J, Chu DC, Maxwell A etal. MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis. Gastroenterology 2010; 138: 705-14.
    • (2010) Gastroenterology , vol.138 , pp. 705-714
    • Mann, J.1    Chu, D.C.2    Maxwell, A.3
  • 30
    • 77950565107 scopus 로고    scopus 로고
    • Cross talk between microRNA and epigenetic regulation in adult neurogenesis
    • Szulwach KE, Li X, Smrt RD etal. Cross talk between microRNA and epigenetic regulation in adult neurogenesis. J. Cell Biol. 2010; 189: 127-41.
    • (2010) J. Cell Biol. , vol.189 , pp. 127-141
    • Szulwach, K.E.1    Li, X.2    Smrt, R.D.3
  • 31
    • 36549011761 scopus 로고    scopus 로고
    • Sonic hedgehog is an autocrine viability factor for myofibroblastic hepatic stellate cells
    • Yang L, Wang Y, Mao H etal. Sonic hedgehog is an autocrine viability factor for myofibroblastic hepatic stellate cells. J. Hepatol. 2008; 48: 98-106.
    • (2008) J. Hepatol. , vol.48 , pp. 98-106
    • Yang, L.1    Wang, Y.2    Mao, H.3
  • 32
    • 46349101715 scopus 로고    scopus 로고
    • Hedgehog-mediated paracrine interaction between hepatic stellate cells and marrow-derived mesenchymal stem cells
    • Lin N, Tang Z, Deng M etal. Hedgehog-mediated paracrine interaction between hepatic stellate cells and marrow-derived mesenchymal stem cells. Biochem. Biophys. Res. Commun. 2008; 372: 260-5.
    • (2008) Biochem. Biophys. Res. Commun. , vol.372 , pp. 260-265
    • Lin, N.1    Tang, Z.2    Deng, M.3
  • 33
    • 77952579449 scopus 로고    scopus 로고
    • Non-alcoholic steatohepatitis pathogenesis: role of repair in regulating the disease progression
    • Jung Y, Diehl AM. Non-alcoholic steatohepatitis pathogenesis: role of repair in regulating the disease progression. Dig. Dis. 2010; 28: 225-8.
    • (2010) Dig. Dis. , vol.28 , pp. 225-228
    • Jung, Y.1    Diehl, A.M.2
  • 34
    • 0043092181 scopus 로고    scopus 로고
    • Basal expression of IkappaBalpha is controlled by the mammalian transcriptional repressor RBP-J (CBF1) and its activator Notch1
    • Oakley F, Mann J, Ruddell RG, Pickford J, Weinmaster G, Mann DA. Basal expression of IkappaBalpha is controlled by the mammalian transcriptional repressor RBP-J (CBF1) and its activator Notch1. J. Biol. Chem. 2003; 278: 24359-70.
    • (2003) J. Biol. Chem. , vol.278 , pp. 24359-24370
    • Oakley, F.1    Mann, J.2    Ruddell, R.G.3    Pickford, J.4    Weinmaster, G.5    Mann, D.A.6
  • 36
    • 0035032989 scopus 로고    scopus 로고
    • Changes in WNT/beta-catenin pathway during regulated growth in rat liver regeneration
    • Monga SP, Pediaditakis P, Mule K, Stolz DB, Michalopoulos GK. Changes in WNT/beta-catenin pathway during regulated growth in rat liver regeneration. Hepatology 2001; 33: 1098-109.
    • (2001) Hepatology , vol.33 , pp. 1098-1109
    • Monga, S.P.1    Pediaditakis, P.2    Mule, K.3    Stolz, D.B.4    Michalopoulos, G.K.5
  • 37
    • 77951436593 scopus 로고    scopus 로고
    • Hedgehog signaling is critical for normal liver regeneration after partial hepatectomy in mice
    • Ochoa B, Syn WK, Delgado I etal. Hedgehog signaling is critical for normal liver regeneration after partial hepatectomy in mice. Hepatology 2010; 51: 1712-23.
    • (2010) Hepatology , vol.51 , pp. 1712-1723
    • Ochoa, B.1    Syn, W.K.2    Delgado, I.3
  • 38
    • 33750610840 scopus 로고    scopus 로고
    • Activation of Wnt/beta-catenin pathway during hepatocyte growth factor-induced hepatomegaly in mice
    • Apte U, Zeng G, Muller P etal. Activation of Wnt/beta-catenin pathway during hepatocyte growth factor-induced hepatomegaly in mice. Hepatology 2006; 44: 992-1002.
    • (2006) Hepatology , vol.44 , pp. 992-1002
    • Apte, U.1    Zeng, G.2    Muller, P.3
  • 39
    • 0026705482 scopus 로고
    • Casein kinase II is a negative regulator of c-Jun DNA binding and AP-1 activity
    • Lin A, Frost J, Deng T etal. Casein kinase II is a negative regulator of c-Jun DNA binding and AP-1 activity. Cell 1992; 70: 777-89.
    • (1992) Cell , vol.70 , pp. 777-789
    • Lin, A.1    Frost, J.2    Deng, T.3
  • 40
    • 0037043777 scopus 로고    scopus 로고
    • Functional interaction of protein kinase CK2 and c-Myc in lymphomagenesis
    • Channavajhala P, Seldin DC. Functional interaction of protein kinase CK2 and c-Myc in lymphomagenesis. Oncogene 2002; 21: 5280-8.
    • (2002) Oncogene , vol.21 , pp. 5280-5288
    • Channavajhala, P.1    Seldin, D.C.2
  • 41
    • 0034647693 scopus 로고    scopus 로고
    • Signal-dependent and -independent degradation of free and NF-kappa B-bound IkappaBalpha
    • Pando MP, Verma IM. Signal-dependent and -independent degradation of free and NF-kappa B-bound IkappaBalpha. J. Biol. Chem. 2000; 275: 21278-86.
    • (2000) J. Biol. Chem. , vol.275 , pp. 21278-21286
    • Pando, M.P.1    Verma, I.M.2
  • 42
    • 0038267245 scopus 로고    scopus 로고
    • CK2 phosphorylation of the armadillo repeat region of beta-catenin potentiates Wnt signaling
    • Song DH, Dominguez I, Mizuno J, Kaut M, Mohr SC, Seldin DC. CK2 phosphorylation of the armadillo repeat region of beta-catenin potentiates Wnt signaling. J. Biol. Chem. 2003; 278: 24018-25.
    • (2003) J. Biol. Chem. , vol.278 , pp. 24018-24025
    • Song, D.H.1    Dominguez, I.2    Mizuno, J.3    Kaut, M.4    Mohr, S.C.5    Seldin, D.C.6
  • 43
    • 79952296431 scopus 로고    scopus 로고
    • Phosphorylation of AKT/PKB by CK2 is necessary for the AKT-dependent up-regulation of beta-catenin transcriptional activity
    • Ponce DP, Maturana JL, Cabello P etal. Phosphorylation of AKT/PKB by CK2 is necessary for the AKT-dependent up-regulation of beta-catenin transcriptional activity. J. Cell. Physiol. 2011; 226: 1953-9.
    • (2011) J. Cell. Physiol. , vol.226 , pp. 1953-1959
    • Ponce, D.P.1    Maturana, J.L.2    Cabello, P.3
  • 44
    • 0345006147 scopus 로고    scopus 로고
    • Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas
    • de La CA, Romagnolo B, Billuart P etal. Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas. Proc. Natl. Acad. Sci. U.S.A. 1998; 95: 8847-51.
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 8847-8851
    • de La, C.A.1    Romagnolo, B.2    Billuart, P.3
  • 45
    • 0033584421 scopus 로고    scopus 로고
    • Mutation of beta-catenin is an early event in chemically induced mouse hepatocellular carcinogenesis
    • Devereux TR, Anna CH, Foley JF, White CM, Sills RC, Barrett JC. Mutation of beta-catenin is an early event in chemically induced mouse hepatocellular carcinogenesis. Oncogene 1999; 18: 4726-33.
    • (1999) Oncogene , vol.18 , pp. 4726-4733
    • Devereux, T.R.1    Anna, C.H.2    Foley, J.F.3    White, C.M.4    Sills, R.C.5    Barrett, J.C.6
  • 46
    • 77954419078 scopus 로고    scopus 로고
    • Dlk-1, a cell surface antigen on foetal hepatic stem/progenitor cells, is expressed in hepatocellular, colon, pancreas and breast carcinomas at a high frequency
    • Yanai H, Nakamura K, Hijioka S etal. Dlk-1, a cell surface antigen on foetal hepatic stem/progenitor cells, is expressed in hepatocellular, colon, pancreas and breast carcinomas at a high frequency. J. Biochem. 2010; 148: 85-92.
    • (2010) J. Biochem. , vol.148 , pp. 85-92
    • Yanai, H.1    Nakamura, K.2    Hijioka, S.3


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