The JAK2 variant rs10758669 in Crohn's disease: Altering the intestinal barrier as one mechanism of action

International Journal of Colorectal Disease

Volumn 27, Issue 5, 2012, Pages 565-573

  Prager, Matthias ^a   Büttner, Janine ^a   Haas, Verena ^b   Baumgart, Daniel C ^a   Sturm, Andreas ^a   Zeitz, Martin ^a   Büning, Carsten ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

Crohn's disease; Inflammatory bowel disease; Intestinal permeability; IRGM; JAK2; STAT3; Ulcerative colitis

Indexed keywords

INTERLEUKIN 23; LACTULOSE; MANNITOL;

ADULT; AGED; ALLELE; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; CROHN DISEASE; DISEASE ASSOCIATION; FEMALE; GASTROINTESTINAL PERMEABILITY; GENE; GENETIC VARIABILITY; GERMANY; HUMAN; INTESTINE BARRIER; JAK2 GENE; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; PERMEABILITY BARRIER; PRIORITY JOURNAL; REMISSION; STAT3 GENE; ULCERATIVE COLITIS;

ADULT; COLITIS, ULCERATIVE; CROHN DISEASE; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPING TECHNIQUES; GTP-BINDING PROTEINS; HUMANS; INTESTINAL ABSORPTION; INTESTINES; JANUS KINASE 2; MALE; NOD2 SIGNALING ADAPTOR PROTEIN; PERMEABILITY; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR;

EID: 84863009612     PISSN: 01791958     EISSN: 14321262     Source Type: Journal    
DOI: 10.1007/s00384-011-1345-y     Document Type: Article

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