Domain specific overexpression of TIMP-2 and TIMP-3 reveals MMP-independent functions of TIMPs during Xenopus laevis development

Biochemistry and Cell Biology

Volumn 90, Issue 4, 2012, Pages 585-595

  Nieuwesteeg, M A ^a   Walsh, L A ^a   Fox, M A ^a   Damjanovski, S ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

MMP regulation; TIMP domains; Xenopus

Indexed keywords

C-TERMINAL DOMAINS; CELL MIGRATION; CELL SIGNALLING; DOMAIN SPECIFIC; ENZYMATIC ACTION; EXTRACELLULAR MATRICES; IN-VIVO; MATRIX METALLOPROTEINASES; METALLOPROTEINASES; MMP ACTIVITY; MMP REGULATION; N-TERMINAL DOMAINS; N-TERMINALS; OVER-EXPRESSION; SECRETED PROTEIN; TISSUE INHIBITOR; XENOPUS; XENOPUS LAEVIS;

DEFECTS; ENZYME INHIBITION; TISSUE;

PLANTS (BOTANY);

GELATINASE A; GELATINASE B; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TISSUE INHIBITOR OF METALLOPROTEINASE 3;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DEATH; DEVELOPMENTAL DISORDER; EMBRYO; EMBRYO DEVELOPMENT; ENZYME ACTIVITY; GENE OVEREXPRESSION; GENE SEQUENCE; GENETIC CONSERVATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PROTEIN DOMAIN; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; XENOPUS LAEVIS;

ANIMALS; EMBRYO, NONMAMMALIAN; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASES; TISSUE INHIBITOR OF METALLOPROTEINASE-2; TISSUE INHIBITOR OF METALLOPROTEINASE-3; XENOPUS LAEVIS;

XENOPUS LAEVIS;

EID: 84863005529     PISSN: 08298211     EISSN: 12086002     Source Type: Journal    
DOI: 10.1139/o2012-014     Document Type: Article

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