Phage display of tissue inhibitor of metalloproteinases-2 (TIMP-2): Identification of selective inhibitors of collagenase-1 (metalloproteinase 1 (MMP-1))

Journal of Biological Chemistry

Volumn 286, Issue 36, 2011, Pages 31761-31770

  Bahudhanapati, Harinath ^a,c   Zhang, Yingnan ^a   Sidhu, Sachdev S ^b,d   Brew, Keith ^a  

^a FLORIDA ATLANTIC UNIVERSITY   (United States)

^b GENENTECH INC   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d ONTARIO INSTITUTE FOR CANCER RESEARCH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BROAD SPECTRUM; COLLAGENASE; EXTRACELLULAR MATRICES; INHIBITORY ACTIVITY; MATRIX METALLOPROTEINASES; METALLOPROTEINASES; N-TERMINAL DOMAINS; NANOMOLAR; PHAGE DISPLAY; SELECTIVE INHIBITORS; TISSUE INHIBITOR; TISSUE INHIBITOR OF METALLOPROTEINASES-2; WILD TYPES;

BLOOD VESSELS; ENZYME ACTIVITY; ENZYME INHIBITION;

TISSUE;

ALANINE; ASPARTIC ACID; CYSTEINE; ENZYME INHIBITOR; GLUTAMINE; INTERSTITIAL COLLAGENASE; INTERSTITIAL COLLAGENASE INHIBITOR; SERINE; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE 2; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTHRITIS; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME ACTIVITY; FIBROSIS; MOLECULAR CLONING; MOLECULAR LIBRARY; MUTATION; NEOPLASM; NONHUMAN; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN VARIANT; RANDOMIZATION;

AMINO ACID SUBSTITUTION; COLLAGENASES; GENETIC VARIATION; HUMANS; MATRIX METALLOPROTEINASE 1; METALLOPROTEASES; PEPTIDE LIBRARY; TISSUE INHIBITOR OF METALLOPROTEINASE-2;

EID: 80052401858     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.253328     Document Type: Article

References (41)

1. Hamze, A. B., Wei, S., Bahudhanapati, H., Kota, S., Acharya, K. R., and Brew, K. (2007) Protein Sci. 16, 1905-1913
2. Stracke, J. O., Hutton, M., Stewart, M., Pendás, A. M., Smith, B., López-Otin, C., Murphy, G., and Knäuper, V. (2000) J. Biol. Chem. 275, 14809-14816
3. Olson, M. W., Bernardo, M. M., Pietila, M., Gervasi, D. C., Toth, M., Kotra, L. P., Massova, I., Mobashery, S., and Fridman, R. (2000) J. Biol. Chem. 275, 2661-2668
4. Kashiwagi, M., Tortorella, M., Nagase, H., and Brew, K. (2001) J. Biol. Chem. 276, 12501-12504
5. Amour, A., Slocombe, P. M., Webster, A., Butler, M., Knight, C. G., Smith, B. J., Stephens, P. E., Shelley, C., Hutton, M., Knäuper, V., Docherty, A. J., and Murphy, G. (1998) FEBS Lett. 435, 39-44
6. Brew, K., and Nagase, H. (2010) Biochim. Biophys. Acta 1803, 55-71
7. Murphy, G., and Nagase, H. (2008) Mol. Aspects Med. 29, 290-308
8. Gomis-Rüth, F. X., Maskos, K., Betz, M., Bergner, A., Huber, R., Suzuki, K., Yoshida, N., Nagase, H., Brew, K., Bourenkov, G. P., Bartunik, H., and Bode, W. (1997) Nature 389, 77-81
9. Iyer, S., Wei, S., Brew, K., and Acharya, K. R. (2007) J. Biol. Chem. 282, 364-371
10. Fernandez-Catalan, C., Bode, W., Huber, R., Turk, D., Calvete, J. J., Lichte, A., Tschesche, H., and Maskos, K. (1998) EMBO J. 17, 5238-5248
11. Maskos, K., Lang, R., Tschesche, H., and Bode, W. (2007) J. Mol. Biol. 366, 1222-1231
12. Grossman, M., Tworowski, D., Dym, O., Lee, M. H., Levy, Y., Murphy, G., and Sagi, I. (2010) Biochemistry 49, 6184-6192
13. Wei, S., Kashiwagi, M., Kota, S., Xie, Z., Nagase, H., and Brew, K. (2005) J. Biol. Chem. 280, 32877-32882
14. Wei, S., Xie, Z., Filenova, E., and Brew, K. (2003) Biochemistry 42, 12200-12207
15. Wei, S., Chen, Y., Chung, L., Nagase, H., and Brew, K. (2003) J. Biol. Chem. 278, 9831-9834
16. Overall, C. M., and Kleifeld, O. (2006) Nat. Rev. Cancer 6, 227-239
17. van 't Veer, L. J., Dai, H., van de Vijver, M. J., He, Y. D., Hart, A. A., Mao, M., Peterse, H. L., van der Kooy, K., Marton, M. J., Witteveen, A. T., Schreiber, G. J., Kerkhoven, R. M., Roberts, C., Linsley, P. S., Bernards, R., and Friend, S. H. (2002) Nature 415, 530-536
18. Minn, A. J., Gupta, G. P., Siegel, P. M., Bos, P. D., Shu, W., Giri, D. D., Viale, A., Olshen, A. B., Gerald, W. L., and Massagué, J. (2005) Nature 436, 518-524
19. Murray, G. I., Duncan, M. E., O'Neil, P., Melvin, W. T., and Fothergill, J. E. (1996) Nat. Med. 2, 461-462
20. Witty, J. P., Lempka, T., Coffey, R. J., Jr., and Matrisian, L. M. (1995) Cancer Res. 55, 1401-1406
21. McCawley, L. J., Crawford, H. C., King, L. E., Jr., Mudgett, J., and Matrisian, L. M. (2004) Cancer Res. 64, 6965-6972
22. Skelton, N. J., Koehler, M. F., Zobel, K., Wong, W. L., Yeh, S., Pisabarro, M. T., Yin, J. P., Lasky, L. A., and Sidhu, S. S. (2003) J. Biol. Chem. 278, 7645-7654
23. Tonikian, R., Zhang, Y., Boone, C., and Sidhu, S. S. (2007) Nat. Protoc. 2, 1368-1386
24. Kunkel, T. A., Roberts, J. D., and Zakour, R. A. (1987) Methods Enzymol. 154, 367-382
25. Zhang, J. P., Wang, Q., Smith, T. R., Hurst, W. E., and Sulpizio, T. (2005) Biotechnol. Prog. 21, 1220-1225
26. Pettersen, E. F., Goddard, T. D., Huang, C. C., Couch, G. S., Greenblatt, D. M., Meng, E. C., and Ferrin, T. E. (2004) J. Comput. Chem. 25, 1605-1612
27. Arumugam, S., Gao, G., Patton, B. L., Semenchenko, V., Brew, K., and Van Doren, S. R. (2003) J. Mol. Biol. 327, 719-734
28. Iyer, S., Visse, R., Nagase, H., and Acharya, K. R. (2006) J. Mol. Biol. 362, 78-88
29. Emsley, P., and Cowtan, K. (2004) Acta Crystallogr. D Biol. Crystallogr. 60, 2126-2132
30. Guex, N., and Peitsch, M. C. (1997) Electrophoresis 18, 2714-2723
31. Arnold, K., Bordoli, L., Kopp, J., and Schwede, T. (2006) Bioinformatics 22, 195-201
32. Welch, A. R., Holman, C. M., Huber, M., Brenner, M. C., Browner, M. F., and Van Wart, H. E. (1996) Biochemistry 35, 10103-10109
33. Dennis, M. S., and Lazarus, R. A. (1994) J. Biol. Chem. 269, 22137-22144
34. Dennis, M. S., and Lazarus, R. A. (1994) J. Biol. Chem. 269, 22129-22136
35. Wang, C. I., Yang, Q., and Craik, C. S. (1996) Methods Enzymol. 267, 52-68
36. Gårdsvoll, H., van Zonneveld, A. J., Holm, A., Eldering, E., van Meijer, M., Danø, K., and Pannekoek, H. (1998) FEBS Lett. 431, 170-174
37. Markland, W., Ley, A. C., and Ladner, R. C. (1996) Biochemistry 35, 8058-8067
38. Markland, W., Ley, A. C., Lee, S. W., and Ladner, R. C. (1996) Biochemistry 35, 8045-8057
39. Williamson, R. A., Hutton, M., Vogt, G., Rapti, M., Knäuper, V., Carr, M. D., and Murphy, G. (2001) J. Biol. Chem. 276, 32966-32970
40. Van Doren, S. R., Wei, S., Gao, G., DaGue, B. B., Palmier, M. O., Bahudhanapati, H., and Brew, K. (2008) Biopolymers 89, 960-968
41. Wu, Y., Wei, S., Van Doren, S. R., and Brew, K. (2011) J. Biol. Chem. 286, 16891-16899