-
1
-
-
2342613652
-
The proteasome: a suitable antineoplastic target
-
Adams J. The proteasome: a suitable antineoplastic target. Nat. Rev. Cancer 2004, 4:349-360.
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 349-360
-
-
Adams, J.1
-
2
-
-
31444449462
-
Role of the unfolded protein response in cell death
-
Kim R., Emi M., Tanabe K., Murakami S. Role of the unfolded protein response in cell death. Apoptosis 2006, 11:5-13.
-
(2006)
Apoptosis
, vol.11
, pp. 5-13
-
-
Kim, R.1
Emi, M.2
Tanabe, K.3
Murakami, S.4
-
3
-
-
7644242953
-
Proteasome inhibitor PS-341 induces apoptosis through induction of endoplasmic reticulum stress-reactive oxygen species in head and neck squamous cell carcinoma cells
-
Fribley A., Zeng Q., Wang C.Y. Proteasome inhibitor PS-341 induces apoptosis through induction of endoplasmic reticulum stress-reactive oxygen species in head and neck squamous cell carcinoma cells. Mol. Cell. Biol. 2004, 24:9695-9704.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 9695-9704
-
-
Fribley, A.1
Zeng, Q.2
Wang, C.Y.3
-
4
-
-
4444311881
-
Simultaneous inhibition of hsp 90 and the proteasome promotes protein ubiquitination, causes endoplasmic reticulum-derived cytosolic vacuolization, and enhances antitumor activity
-
Mimnaugh E.G., Xu W., Vos M., Yuan X., Isaacs J.S., Bisht K.S., Gius D., Neckers L. Simultaneous inhibition of hsp 90 and the proteasome promotes protein ubiquitination, causes endoplasmic reticulum-derived cytosolic vacuolization, and enhances antitumor activity. Mol. Cancer Ther. 2004, 3:551-566.
-
(2004)
Mol. Cancer Ther.
, vol.3
, pp. 551-566
-
-
Mimnaugh, E.G.1
Xu, W.2
Vos, M.3
Yuan, X.4
Isaacs, J.S.5
Bisht, K.S.6
Gius, D.7
Neckers, L.8
-
5
-
-
29244454269
-
Bortezomib sensitizes pancreatic cancer cells to endoplasmic reticulum stress-mediated apoptosis
-
Nawrocki S.T., Carew J.S., Pino M.S., Highshaw R.A., Dunner K., Huang P., Abbruzzese J.L., McConkey D.J. Bortezomib sensitizes pancreatic cancer cells to endoplasmic reticulum stress-mediated apoptosis. Cancer Res. 2005, 65:11658-11666.
-
(2005)
Cancer Res.
, vol.65
, pp. 11658-11666
-
-
Nawrocki, S.T.1
Carew, J.S.2
Pino, M.S.3
Highshaw, R.A.4
Dunner, K.5
Huang, P.6
Abbruzzese, J.L.7
McConkey, D.J.8
-
6
-
-
33744539521
-
Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells
-
Obeng E.A., Carlson L.M., Gutman D.M., Harrington W.J., Lee K.P., Boise L.H. Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells. Blood 2006, 107:4907-4916.
-
(2006)
Blood
, vol.107
, pp. 4907-4916
-
-
Obeng, E.A.1
Carlson, L.M.2
Gutman, D.M.3
Harrington, W.J.4
Lee, K.P.5
Boise, L.H.6
-
7
-
-
34347258502
-
Different induction of GRP78 and CHOP as a predictor of sensitivity to proteasome inhibitors in thyroid cancer cells
-
Wang H.Q., Du Z.X., Zhang H.Y., Gao D.X. Different induction of GRP78 and CHOP as a predictor of sensitivity to proteasome inhibitors in thyroid cancer cells. Endocrinology 2007, 148:3258-3270.
-
(2007)
Endocrinology
, vol.148
, pp. 3258-3270
-
-
Wang, H.Q.1
Du, Z.X.2
Zhang, H.Y.3
Gao, D.X.4
-
8
-
-
0026546365
-
CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription
-
Ron D., Habener J.F. CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription. Genes Dev. 1992, 6:439-453.
-
(1992)
Genes Dev.
, vol.6
, pp. 439-453
-
-
Ron, D.1
Habener, J.F.2
-
9
-
-
0024436187
-
Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents
-
Fornace A.J., Nebert D.W., Hollander M.C., Luethy J.D., Papathanasiou M., Fargnoli J., Holbrook N.J. Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents. Mol. Cell. Biol. 1989, 9:4196-4203.
-
(1989)
Mol. Cell. Biol.
, vol.9
, pp. 4196-4203
-
-
Fornace, A.J.1
Nebert, D.W.2
Hollander, M.C.3
Luethy, J.D.4
Papathanasiou, M.5
Fargnoli, J.6
Holbrook, N.J.7
-
10
-
-
0037048302
-
Genomic instability, centrosome amplification, cell cycle checkpoints and Gadd45a
-
Hollander M.C., Fornace A.J. Genomic instability, centrosome amplification, cell cycle checkpoints and Gadd45a. Oncogene 2002, 21:6228-6233.
-
(2002)
Oncogene
, vol.21
, pp. 6228-6233
-
-
Hollander, M.C.1
Fornace, A.J.2
-
11
-
-
0032885388
-
Mammalian caspases: structure, activation, substrates, and functions during apoptosis
-
Earnshaw W.C., Martins L.M., Kaufmann S.H. Mammalian caspases: structure, activation, substrates, and functions during apoptosis. Annu. Rev. Biochem. 1999, 68:383-424.
-
(1999)
Annu. Rev. Biochem.
, vol.68
, pp. 383-424
-
-
Earnshaw, W.C.1
Martins, L.M.2
Kaufmann, S.H.3
-
12
-
-
15944369290
-
ER stress signaling by regulated splicing: IRE1/HAC1/XBP1
-
Back S.H., Schroder M., Lee K., Zhang K., Kaufman R.J. ER stress signaling by regulated splicing: IRE1/HAC1/XBP1. Methods 2005, 35:395-416.
-
(2005)
Methods
, vol.35
, pp. 395-416
-
-
Back, S.H.1
Schroder, M.2
Lee, K.3
Zhang, K.4
Kaufman, R.J.5
-
13
-
-
20944441740
-
The anti-apoptotic, glucocorticoid receptor cochaperone protein BAG-1 is a long-term target for the actions of mood stabilizers
-
Zhou R., Gray N.A., Yuan P., Li X., Chen J., Chen G., Damschroder-Williams P., Du J., Zhang L., Manji H.K. The anti-apoptotic, glucocorticoid receptor cochaperone protein BAG-1 is a long-term target for the actions of mood stabilizers. J. Neurosci. 2005, 25:4493-4502.
-
(2005)
J. Neurosci.
, vol.25
, pp. 4493-4502
-
-
Zhou, R.1
Gray, N.A.2
Yuan, P.3
Li, X.4
Chen, J.5
Chen, G.6
Damschroder-Williams, P.7
Du, J.8
Zhang, L.9
Manji, H.K.10
-
14
-
-
10444226462
-
ER stress and the unfolded protein response
-
Schroder M., Kaufman R.J. ER stress and the unfolded protein response. Mutat. Res. 2005, 569:29-63.
-
(2005)
Mutat. Res.
, vol.569
, pp. 29-63
-
-
Schroder, M.1
Kaufman, R.J.2
-
15
-
-
0029927983
-
Induction of the mammalian stress response gene GADD153 by oxidative stress: role of AP-1 element
-
Guyton K.Z., Xu Q., Holbrook N.J. Induction of the mammalian stress response gene GADD153 by oxidative stress: role of AP-1 element. Biochem. J. 1996, 314(Pt 2):547-554.
-
(1996)
Biochem. J.
, vol.314
, Issue.PART 2
, pp. 547-554
-
-
Guyton, K.Z.1
Xu, Q.2
Holbrook, N.J.3
-
16
-
-
0033815971
-
ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response
-
Yoshida H., Okada T., Haze K., Yanagi H., Yura T., Negishi M., Mori K. ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response. Mol. Cell. Biol. 2000, 20:6755-6767.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 6755-6767
-
-
Yoshida, H.1
Okada, T.2
Haze, K.3
Yanagi, H.4
Yura, T.5
Negishi, M.6
Mori, K.7
-
17
-
-
42049093407
-
Role of the repressor JDP2 in the amino acid-regulated transcription of CHOP
-
Cherasse Y., Chaveroux C., Jousse C., Maurin A.C., Carraro V., Parry L., Fafournoux P., Bruhat A. Role of the repressor JDP2 in the amino acid-regulated transcription of CHOP. FEBS Lett. 2008, 582:1537-1541.
-
(2008)
FEBS Lett.
, vol.582
, pp. 1537-1541
-
-
Cherasse, Y.1
Chaveroux, C.2
Jousse, C.3
Maurin, A.C.4
Carraro, V.5
Parry, L.6
Fafournoux, P.7
Bruhat, A.8
-
18
-
-
0036314984
-
Two distinct stress signaling pathways converge upon the CHOP promoter during the mammalian unfolded protein response
-
Ma Y., Brewer J.W., Diehl J.A., Hendershot L.M. Two distinct stress signaling pathways converge upon the CHOP promoter during the mammalian unfolded protein response. J. Mol. Biol. 2002, 318:1351-1365.
-
(2002)
J. Mol. Biol.
, vol.318
, pp. 1351-1365
-
-
Ma, Y.1
Brewer, J.W.2
Diehl, J.A.3
Hendershot, L.M.4
-
19
-
-
0034671837
-
CHOP gene expression in response to endoplasmic-reticular stress requires NFY interaction with different domains of a conserved DNA-binding element
-
Ubeda M., Habener J.F. CHOP gene expression in response to endoplasmic-reticular stress requires NFY interaction with different domains of a conserved DNA-binding element. Nucleic Acids Res. 2000, 28:4987-4997.
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 4987-4997
-
-
Ubeda, M.1
Habener, J.F.2
-
20
-
-
1842843855
-
Roles of CHOP/GADD153 in endoplasmic reticulum stress
-
Oyadomari S., Mori M. Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ. 2004, 11:381-389.
-
(2004)
Cell Death Differ.
, vol.11
, pp. 381-389
-
-
Oyadomari, S.1
Mori, M.2
-
21
-
-
37849038317
-
The chop gene contains an element for the positive regulation of the mitochondrial unfolded protein response
-
Horibe T., Hoogenraad N.J. The chop gene contains an element for the positive regulation of the mitochondrial unfolded protein response. PLoS One 2007, 2:e835.
-
(2007)
PLoS One
, vol.2
-
-
Horibe, T.1
Hoogenraad, N.J.2
-
22
-
-
0037968290
-
Myocardin is a key regulator of CArG-dependent transcription of multiple smooth muscle marker genes
-
Yoshida T., Sinha S., Dandre F., Wamhoff B.R., Hoofnagle M.H., Kremer B.E., Wang D.Z., Olson E.N., Owens G.K. Myocardin is a key regulator of CArG-dependent transcription of multiple smooth muscle marker genes. Circ. Res. 2003, 92:856-864.
-
(2003)
Circ. Res.
, vol.92
, pp. 856-864
-
-
Yoshida, T.1
Sinha, S.2
Dandre, F.3
Wamhoff, B.R.4
Hoofnagle, M.H.5
Kremer, B.E.6
Wang, D.Z.7
Olson, E.N.8
Owens, G.K.9
-
24
-
-
29244462498
-
Coordination of ER and oxidative stress signaling: the PERK/Nrf2 signaling pathway
-
Cullinan S.B., Diehl J.A. Coordination of ER and oxidative stress signaling: the PERK/Nrf2 signaling pathway. Int. J. Biochem. Cell Biol. 2006, 38:317-332.
-
(2006)
Int. J. Biochem. Cell Biol.
, vol.38
, pp. 317-332
-
-
Cullinan, S.B.1
Diehl, J.A.2
-
25
-
-
2442542312
-
PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress
-
Cullinan S.B., Diehl J.A. PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress. J. Biol. Chem. 2004, 279:20108-20117.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 20108-20117
-
-
Cullinan, S.B.1
Diehl, J.A.2
-
26
-
-
0141752795
-
Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival
-
Cullinan S.B., Zhang D., Hannink M., Arvisais E., Kaufman R.J., Diehl J.A. Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival. Mol. Cell. Biol. 2003, 23:7198-7209.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 7198-7209
-
-
Cullinan, S.B.1
Zhang, D.2
Hannink, M.3
Arvisais, E.4
Kaufman, R.J.5
Diehl, J.A.6
-
27
-
-
0037424262
-
Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival
-
Kwak M.K., Wakabayashi N., Itoh K., Motohashi H., Yamamoto M., Kensler T.W. Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival. J. Biol. Chem. 2003, 278:8135-8145.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 8135-8145
-
-
Kwak, M.K.1
Wakabayashi, N.2
Itoh, K.3
Motohashi, H.4
Yamamoto, M.5
Kensler, T.W.6
-
28
-
-
0038146898
-
Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis
-
Lee J.M., Calkins M.J., Chan K., Kan Y.W., Johnson J.A. Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis. J. Biol. Chem. 2003, 278:12029-12038.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 12029-12038
-
-
Lee, J.M.1
Calkins, M.J.2
Chan, K.3
Kan, Y.W.4
Johnson, J.A.5
-
29
-
-
0037106099
-
Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray
-
Thimmulappa R.K., Mai K.H., Srisuma S., Kensler T.W., Yamamoto M., Biswal S. Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray. Cancer Res. 2002, 62:5196-5203.
-
(2002)
Cancer Res.
, vol.62
, pp. 5196-5203
-
-
Thimmulappa, R.K.1
Mai, K.H.2
Srisuma, S.3
Kensler, T.W.4
Yamamoto, M.5
Biswal, S.6
-
30
-
-
0033634654
-
Regulated translation initiation controls stress-induced gene expression in mammalian cells
-
Harding H.P., Novoa I., Zhang Y., Zeng H., Wek R., Schapira M., Ron D. Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol. Cell 2000, 6:1099-1108.
-
(2000)
Mol. Cell
, vol.6
, pp. 1099-1108
-
-
Harding, H.P.1
Novoa, I.2
Zhang, Y.3
Zeng, H.4
Wek, R.5
Schapira, M.6
Ron, D.7
-
31
-
-
57349103343
-
Deoxyribonucleic acid profiling analysis of 40 human thyroid cancer cell lines reveals cross-contamination resulting in cell line redundancy and misidentification
-
Schweppe R.E., Klopper J.P., Korch C., Pugazhenthi U., Benezra M., Knauf J.A., Fagin J.A., Marlow L.A., Copland J.A., Smallridge R.C., et al. Deoxyribonucleic acid profiling analysis of 40 human thyroid cancer cell lines reveals cross-contamination resulting in cell line redundancy and misidentification. J. Clin. Endocrinol. Metab. 2008, 93:4331-4341.
-
(2008)
J. Clin. Endocrinol. Metab.
, vol.93
, pp. 4331-4341
-
-
Schweppe, R.E.1
Klopper, J.P.2
Korch, C.3
Pugazhenthi, U.4
Benezra, M.5
Knauf, J.A.6
Fagin, J.A.7
Marlow, L.A.8
Copland, J.A.9
Smallridge, R.C.10
-
32
-
-
58149375078
-
Proteasome inhibitor MG132 induces BAG3 expression through activation of heat shock factor 1
-
Du Z.X., Zhang H.Y., Meng X., Gao Y.Y., Zou R.L., Liu B.Q., Guan Y., Wang H.Q. Proteasome inhibitor MG132 induces BAG3 expression through activation of heat shock factor 1. J. Cell. Physiol. 2009, 218:631-637.
-
(2009)
J. Cell. Physiol.
, vol.218
, pp. 631-637
-
-
Du, Z.X.1
Zhang, H.Y.2
Meng, X.3
Gao, Y.Y.4
Zou, R.L.5
Liu, B.Q.6
Guan, Y.7
Wang, H.Q.8
-
33
-
-
23844475091
-
Nuclear import and export signals in control of Nrf2
-
Jain A.K., Bloom D.A., Jaiswal A.K. Nuclear import and export signals in control of Nrf2. J. Biol. Chem. 2005, 280:29158-29168.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 29158-29168
-
-
Jain, A.K.1
Bloom, D.A.2
Jaiswal, A.K.3
-
34
-
-
79955647069
-
Proteasome inhibition induces a p38 MAPK pathway-dependent antiapoptotic program via Nrf2 in thyroid cancer cells
-
Du Z.X., Yan Y., Zhang H.Y., Liu B.Q., Gao Y.Y., Niu X.F., Meng X., Wang H.Q. Proteasome inhibition induces a p38 MAPK pathway-dependent antiapoptotic program via Nrf2 in thyroid cancer cells. J. Clin. Endocrinol. Metab. 2011, 96:E763-E771.
-
(2011)
J. Clin. Endocrinol. Metab.
, vol.96
-
-
Du, Z.X.1
Yan, Y.2
Zhang, H.Y.3
Liu, B.Q.4
Gao, Y.Y.5
Niu, X.F.6
Meng, X.7
Wang, H.Q.8
-
35
-
-
64749106188
-
Role of oxidative stress and intracellular glutathione in the sensitivity to apoptosis induced by proteasome inhibitor in thyroid cancer cells
-
Du Z.X., Zhang H.Y., Meng X., Guan Y., Wang H.Q. Role of oxidative stress and intracellular glutathione in the sensitivity to apoptosis induced by proteasome inhibitor in thyroid cancer cells. BMC Cancer 2009, 9:56.
-
(2009)
BMC Cancer
, vol.9
, pp. 56
-
-
Du, Z.X.1
Zhang, H.Y.2
Meng, X.3
Guan, Y.4
Wang, H.Q.5
-
36
-
-
78049520517
-
Implication of oxygen-regulated protein 150 (ORP150) in apoptosis induced by proteasome inhibitors in human thyroid cancer cells
-
Gao Y.Y., Liu B.Q., Du Z.X., Zhang H.Y., Niu X.F., Wang H.Q. Implication of oxygen-regulated protein 150 (ORP150) in apoptosis induced by proteasome inhibitors in human thyroid cancer cells. J. Clin. Endocrinol. Metab. 2010, 95:E319-E326.
-
(2010)
J. Clin. Endocrinol. Metab.
, vol.95
-
-
Gao, Y.Y.1
Liu, B.Q.2
Du, Z.X.3
Zhang, H.Y.4
Niu, X.F.5
Wang, H.Q.6
-
37
-
-
0035877643
-
Identification of activating transcription factor 4 (ATF4) as an Nrf2-interacting protein. Implication for heme oxygenase-1 gene regulation
-
He C.H., Gong P., Hu B., Stewart D., Choi M.E., Choi A.M., Alam J. Identification of activating transcription factor 4 (ATF4) as an Nrf2-interacting protein. Implication for heme oxygenase-1 gene regulation. J. Biol. Chem. 2001, 276:20858-20865.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 20858-20865
-
-
He, C.H.1
Gong, P.2
Hu, B.3
Stewart, D.4
Choi, M.E.5
Choi, A.M.6
Alam, J.7
-
38
-
-
0032054744
-
CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum
-
Zinszner H., Kuroda M., Wang X., Batchvarova N., Lightfoot R.T., Remotti H., Stevens J.L., Ron D. CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum. Genes Dev. 1998, 12:982-995.
-
(1998)
Genes Dev.
, vol.12
, pp. 982-995
-
-
Zinszner, H.1
Kuroda, M.2
Wang, X.3
Batchvarova, N.4
Lightfoot, R.T.5
Remotti, H.6
Stevens, J.L.7
Ron, D.8
-
39
-
-
0033830234
-
Amino acids control mammalian gene transcription: activating transcription factor 2 is essential for the amino acid responsiveness of the CHOP promoter
-
Bruhat A., Jousse C., Carraro V., Reimold A.M., Ferrara M., Fafournoux P. Amino acids control mammalian gene transcription: activating transcription factor 2 is essential for the amino acid responsiveness of the CHOP promoter. Mol. Cell. Biol. 2000, 20:7192-7204.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 7192-7204
-
-
Bruhat, A.1
Jousse, C.2
Carraro, V.3
Reimold, A.M.4
Ferrara, M.5
Fafournoux, P.6
-
40
-
-
0034731459
-
CHOP/GADD153 gene expression response to cellular stresses inhibited by prior exposure to ultraviolet light wavelength band C (UVC). Inhibitory sequence mediating the UVC response localized to exon 1
-
Schmitt-Ney M., Habener J.F. CHOP/GADD153 gene expression response to cellular stresses inhibited by prior exposure to ultraviolet light wavelength band C (UVC). Inhibitory sequence mediating the UVC response localized to exon 1. J. Biol. Chem. 2000, 275:40839-40845.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 40839-40845
-
-
Schmitt-Ney, M.1
Habener, J.F.2
-
41
-
-
0032953192
-
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
-
Itoh K., Wakabayashi N., Katoh Y., Ishii T., Igarashi K., Engel J.D., Yamamoto M. Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Genes Dev. 1999, 13:76-86.
-
(1999)
Genes Dev.
, vol.13
, pp. 76-86
-
-
Itoh, K.1
Wakabayashi, N.2
Katoh, Y.3
Ishii, T.4
Igarashi, K.5
Engel, J.D.6
Yamamoto, M.7
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