Differences in investigations of sudden unexpected deaths in young people in a nationwide setting

International Journal of Legal Medicine

Volumn 126, Issue 2, 2012, Pages 223-229

  Winkel, Bo Gregers ^a,b   Holst, Anders Gaarsdal ^a,b   Theilade, Juliane ^a,b   Kristensen, Ingrid Bayer ^c   Thomsen, Jørgen Lange ^d   Hougen, Hans Petter ^e   Bundgaard, Henning ^b   Svendsen, Jesper Hastrup ^a,b,f   Haunsø, Stig ^a,b,f   Tfelt Hansen, Jacob ^a,b  

^a DANISH NATIONAL RESEARCH FOUNDATION   (Denmark)

^b International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health   (Denmark)

^c AARHUS UNIVERSITY   (Denmark)

^d UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^e UNIVERSITY OF COPENHAGEN   (Denmark)

^f UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Autopsy; Epidemiology; Forensic medicine; Health law; Public health; Sudden death

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; AUTOPSY; CAUSE OF DEATH; CHILD; DENMARK; FEMALE; HUMAN; INCIDENCE; INFANT; MALE; PATHOLOGY; PRESCHOOL CHILD; SUDDEN DEATH; UTILIZATION REVIEW;

ADOLESCENT; ADULT; AUTOPSY; CAUSE OF DEATH; CHILD; CHILD, PRESCHOOL; DEATH, SUDDEN; DENMARK; FEMALE; HUMANS; INCIDENCE; INFANT; MALE; YOUNG ADULT;

EID: 84862992116     PISSN: 09379827     EISSN: 14371596     Source Type: Journal    
DOI: 10.1007/s00414-011-0602-5     Document Type: Article

References (27)

1. Winkel BG, Holst AG, Theilade J, Kristensen IB, Thomsen JL, Ottesen GL, Bundgaard H, Svendsen JH, Haunsø S, Tfelt- Hansen J (2011) Nationwide study of sudden cardiac death in persons aged 1-35 years. Eur Hear J 32:983-990. doi:10.1093/eurheartj/ehq428.
2. Quigley F, Greene M, O'Connor D, Kelly F (2005) A survey of the causes of sudden cardiac death in the under 35-year-age group. Ir Med J 98:232-235.
3. Doolan A, Langlois N, Semsarian C (2004) Causes of sudden cardiac death in young Australians. Med J Aust 180:110-112.
4. Morris V, Keelan T, Leen E, Keating J, Magee H, O'Neill J, Galvin J (2009) Sudden cardiac death in the young: a 1-year post-mortem analysis in the Republic of Ireland. Ir J Med Sci 178:257-261. doi:10.1007/s11845-009-0294-8.
5. Tester DJ, Ackerman MJ (2007) Postmortem long QT syndrome genetic testing for sudden unexplained death in the young. J Am Coll Cardiol 49:240-246. doi:10.1016/j.jacc.2006.10.010.
6. Carturan E, Tester DJ, Brost BC, Basso C, Thiene G, Ackerman MJ (2008) Postmortem genetic testing for conventional autopsynegative sudden unexplained death: an evaluation of different DNA extraction protocols and the feasibility of mutational analysis from archival paraffin-embedded heart tissue. Am J Clin Pathol 129:391-397. doi:10.1309/VLA7TT9EQ05FFVN4.
7. Hudecova K, Simkova I, Gardlik R, Bernadic M (2009) Genetic screening of patients with hypertrophic cardiomyopathy-a new diagnostic strategy for risk stratification? Bratisl Lek List 110:85-92.
8. Tfelt-Hansen J, Winkel BG, Grunnet M, Jespersen T (2010) Inherited cardiac diseases caused by mutations in the Nav1.5 sodium channel. J Cardiovasc Electrophysiol 21:107-115. doi:10.1111/j.1540-8167.2009.01633.x.
9. Corrado D, Basso C, Thiene G (2009) Arrhythmogenic right ventricular cardiomyopathy: an update. Heart 95:766-773. doi:10.1136/hrt.2008.149823.
10. Wierzbicki AS, Graham CA, Young IS, Nicholls DP (2008) Familial combined hyperlipidaemia: under-defined and underdiagnosed? Curr Vasc Pharmacol 6:13-22.
11. Allegue C, Gil R, Blanco-Verea A, Santori M, Rodríguez-Calvo M, Concheiro L, Carracedo A, Brion M (2011) Prevalence of HCM and long QT syndrome mutations in young sudden cardiac death-related cases. Int J Legal Med. doi:10.1007/s00414-011-0572-7.
12. Ferrero-Miliani L, Holst AG, Pehrson S, Morling N, Bundgaard H (2010) Strategy for clinical evaluation and screening of sudden cardiac death relatives. Fundam Clin Pharmacol 24:619-635. doi:10.1111/j.1472-8206.2010.00864. x.
13. Oliva A, Brugada R, D'Aloja E, Boschi I, Partemi S, Brugada J, Pascali VL (2010) State of the art in forensic investigation of sudden cardiac death. Am J Forensic Med Pathol: Official Pub Nat Assoc Med Examiners. doi:10.1097/PAF. 0b013e3181c2dc96.
14. Di Paolo M, Luchini D, Bloise R, Priori SG (2004) Postmortem molecular analysis in victims of sudden unexplained death. Am J Forensic Med Pathol 25:182-184.
15. Rodríguez-Calvo MS, Brion M, Allegue C, Concheiro L, Carracedo A (2008) Molecular genetics of sudden cardiac death. Forensic Sci Int 182:1-12. doi:10.1016/j.forsciint.2008.09.013.
16. Lambiase PD, Elliott PM (2008) Genetic aspects and investigation of sudden death in young people. Clin Med (London, England) 8:607-610.
17. Spooner PM (2009) Sudden cardiac death: the larger problem the larger genome. J Cardiovasc Electrophysiol 20:585-596. doi:10.1111/j.1540-8167.2008. 01419.x.
18. Patel J, Sheppard MN (2009) Cystic tumour of the atrioventricular node: three cases of sudden death. Int J Legal Med 125:139-142. doi:10.1007/s00414- 009-0399-7.
19. Li L, Burke A, He J, Chang L, Zielke HR, Fowler DR (2010) Sudden unexpected death due to inflammatory myofibroblastic tumor of the heart: a case report and review of the literature. Int J Legal Med 125:81-85. doi:10.1007/s00414-010-0496-7.
20. Michaud K, Mangin P, Elger BS (2010) Genetic analysis of sudden cardiac death victims: a survey of current forensic autopsy practices. Int J Legal Med 125:359-366. doi:10.1007/s00414-010-0474-0.
21. Vaartjes I, Hendrix A, Hertogh E, Grobbee D, Doevendans P, Mosterd A, Bots M (2009) Sudden death in persons younger than 40 years of age: incidence and causes. Eur J Cardiovasc Prev Rehabil 16:592-596. doi:10.1097/HJR. 0b013e32832d555b.
22. Corrado D, Basso C, Rizzoli G, Schiavon M, Thiene G (2003) Does sports activity enhance the risk of sudden death in adolescents and young adults? J Am Coll Cardiol 42:1959-1963.
23. Papadakis M, Sharma S, Cox S, Sheppard MN, Panoulas VF, Behr ER (2009) The magnitude of sudden cardiac death in the young: a death certificate-based review in England and Wales. Europace 11:1353-1358. doi:10.1093/europace/eup229.
24. Saukko P (1995) Medicolegal investigative system and sudden death in Scandinavia. Nihon Hoigaku Zasshi=Jpn J LegalMed 49:458-465.
25. Mensah GA, Mokdad AH, Ford ES, Greenlund KJ, Croft JB (2005) State of disparities in cardiovascular health in the United States. Circulation 111:1233-1241. doi:10.1161/01. CIR.0000158136.76824.04.
26. Soo L, HuffN, Gray D, Hampton JR (2001) Geographical distribution of cardiac arrest in Nottinghamshire. Resuscitation 48:137-147.
27. Reinier K, Stecker EC, Vickers C, Gunson K, Jui J, Chugh SS (2006) Incidence of sudden cardiac arrest is higher in areas of low socioeconomic status: a prospective two year study in a large United States community. Resuscitation 70:186-192. doi:10.1016/j.resuscitation.2005.11.018.