Modulation of IFN-γ receptor 1 expression by AP-2α influences IFN-γ sensitivity of cancer cells

American Journal of Pathology

Volumn 180, Issue 2, 2012, Pages 661-671

  Chen, Changguo ^a,b   Guo, Liang ^a   Shi, Ming ^a   Hu, Ming ^b   Hu, Meiru ^a   Yu, Ming ^a   Wang, Tianyou ^c   Song, Lun ^a   Shen, Beifen ^a   Qian, Lu ^a   Guo, Ning ^a  

^a INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^b NAVY GENERAL HOSPITAL   (China)

^c CAPITAL INSTITUTE OF PEDIATRICS   (China)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR 1; STAT1 PROTEIN; TRANSCRIPTION FACTOR AP 2; TRANSCRIPTION FACTOR SP1;

ARTICLE; BREAST CANCER; CANCER CELL; CONTROLLED STUDY; DOWN REGULATION; GENE SILENCING; HELA CELL; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

BREAST NEOPLASMS; CELL LINE, TUMOR; DOWN-REGULATION; FEMALE; GENE SILENCING; HUMANS; INTERFERON-GAMMA; PHOSPHORYLATION; RECEPTORS, INTERFERON; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SP1 TRANSCRIPTION FACTOR; STAT1 TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP-2; TRANSFECTION; UP-REGULATION;

EID: 84862972592     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2011.10.040     Document Type: Article

References (41)

1. K. Schroder, P.J. Hertzog, T. Ravasi, D.A. Hume Interferon-gamma: an overview of signals, mechanisms and functions J Leukoc Biol 75 2004 163 189
2. U. Boehm, T. Klamp, M. Groot, J.C. Howard Cellular responses to interferon-gamma Annu Rev Immunol 15 1997 749 795
3. T. Blankenstein, Z. Qin The role of IFN-gamma in tumor transplantation immunity and inhibition of chemical carcinogenesis Curr Opin Immunol 15 2003 148 154
4. J.D. Bui, R.D. Schreiber Cancer immunosurveillance, immunoediting and inflammation: independent or interdependent processes? Curr Opin Immunol 19 2007 203 208
5. A.S. Dighe, E. Richards, L.J. Old, R.D. Schreiber Enhanced in vivo growth and resistance to rejection of tumor cells expressing dominant negative IFN gamma receptors Immunity 1 1994 447 456
6. G.P. Dunn, H. Ikeda, A.T. Bruce, C. Koebel, R. Uppaluri, J. Bui, R. Chan, M. Diamond, J.M. White, K.C. Sheehan, R.D. Schreiber Interferon-gamma and cancer immunoediting Immunol Res 32 2005 231 245
7. G.P. Dunn, L.J. Old, R.D. Schreiber The immunobiology of cancer immunosurveillance and immunoediting Immunity 21 2004 137 148
8. D.H. Kaplan, V. Shankaran, A.S. Dighe, E. Stockert, M. Aguet, L.J. Old, R.D. Schreiber Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice Proc Natl Acad Sci U S A 95 1998 7556 7561
9. X. Xu, X.Y. Fu, J. Plate, A.S. Chong IFN-gamma induces cell growth inhibition by Fas-mediated apoptosis: requirement of STAT1 protein for up-regulation of Fas and FasL expression Cancer Res 58 1998 2832 2837
10. D. Mumberg, P.A. Monach, S. Wanderling, M. Philip, A.Y. Toledano, R.D. Schreiber, H. Schreiber CD4(+) T cells eliminate MHC class II-negative cancer cells in vivo by indirect effects of IFN-gamma Proc Natl Acad Sci U S A 96 1999 8633 8638
11. H. Nishikawa, T. Kato, I. Tawara, H. Ikeda, K. Kuribayashi, P.M. Allen, R.D. Schreiber, L.J. Old, H. Shiku IFN-gamma controls the generation/activation of CD4+ CD25+ regulatory T cells in antitumor immune response J Immunol 175 2005 4433 4440
12. G. Beatty, Y. Paterson IFN-gamma-dependent inhibition of tumor angiogenesis by tumor-infiltrating CD4+ T cells requires tumor responsiveness to IFN-gamma J Immunol 166 2001 2276 2282
13. E.A. Bach, M. Aguet, R.D. Schreiber The IFN gamma receptor: a paradigm for cytokine receptor signaling Annu Rev Immunol 15 1997 563 591
14. T. Decker, P. Kovarik, A. Meinke GAS elements: a few nucleotides with a major impact on cytokine-induced gene expression J Interferon Cytokine Res 17 1997 121 134
15. G.P. Dunn, C.M. Koebel, R.D. Schreiber Interferons, immunity and cancer immunoediting Nat Rev Immunol 6 2006 836 848
16. Y. Wang, D. Liu, P. Chen, H.P. Koeffler, X. Tong, D. Xie Negative feedback regulation of IFN-gamma pathway by IFN regulatory factor 2 in esophageal cancers Cancer Res 68 2008 1136 1143
17. T.J. Duncan, P. Rolland, S. Deen, I.V. Scott, D.T. Liu, I. Spendlove, L.G. Durrant Loss of IFN gamma receptor is an independent prognostic factor in ovarian cancer Clin Cancer Res 13 2007 4139 4145
18. K.A. Shirey, J.Y. Jung, G.S. Maeder, J.M. Carlin Upregulation of IFN-gamma receptor expression by proinflammatory cytokines influences IDO activation in epithelial cells J Interferon Cytokine Res 26 2006 53 62
19. K.A. Shirey, J.Y. Jung, J.M. Carlin Up-regulation of gamma interferon receptor expression due to Chlamydia-toll-like receptor interaction does not enhance signal transducer and activator of transcription 1 signaling Infect Immun 74 2006 6877 6884
20. S. Sakamoto, T. Taniguchi Identification of a phorbol ester-responsive element in the interferon-gamma receptor 1 chain gene J Biol Chem 276 2001 37237 37241
21. Y. Dong, W.M. Rohn, E.N. Benveniste IFN-gamma regulation of the type IV class II transactivator promoter in astrocytes J Immunol 162 1999 4731 4739
22. S. Grether-Beck, S. Olaizola-Horn, H. Schmitt, M. Grewe, A. Jahnke, J.P. Johnson, K. Briviba, H. Sies, J. Krutmann Activation of transcription factor AP-2 mediates UVA radiation- and singlet oxygen-induced expression of the human intercellular adhesion molecule 1 gene Proc Natl Acad Sci U S A 93 1996 14586 14591
23. M. Shi, D. Liu, H. Duan, L. Qian, L. Wang, L. Niu, H. Zhang, Z. Yong, Z. Gong, L. Song, M. Yu, M. Hu, Q. Xia, B. Shen, N. Guo The β2-adrenergic receptor and Her2 comprise a positive feedback loop in human breast cancer cells Breast Cancer Res Treat 125 2011 351 362
24. S. Juliger, M. Bongartz, A.J. Luty, P.G. Kremsner, J.F. Kun Functional analysis of a promoter variant of the gene encoding the interferon-gamma receptor chain I Immunogenetics 54 2003 675 680
25. G. Suske The Sp-family of transcription factors Gene 238 1999 291 300
26. G. Hagen, S. Muller, M. Beato, G. Suske Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genes Nucleic Acids Res 20 1992 5519 5525
27. W.S. Dynan, R. Tjian The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter Cell 35 1983 79 87
28. K.A. Descheemaeker, S. Wyns, L. Nelles, J. Auwerx, T. Ny, D. Collen Interaction of AP-1-, AP-2-, and Sp1-like proteins with two distinct sites in the upstream regulatory region of the plasminogen activator inhibitor-1 gene mediates the phorbol 12-myristate 13-acetate response J Biol Chem 267 1992 15086 15091
29. A. Lopez-Soto, A. Quinones-Lombrana, R. Lopez-Arbesu, C. Lopez-Larrea, S. Gonzalez Transcriptional regulation of ULBP1, a human ligand of the NKG2D receptor J Biol Chem 281 2006 30419 30430
30. B.C. Turner, J. Zhang, A.A. Gumbs, M.G. Maher, L. Kaplan, D. Carter, P.M. Glazer, H.C. Hurst, B.G. Haffty, T. Williams Expression of AP-2 transcription factors in human breast cancer correlates with the regulation of multiple growth factor signalling pathways Cancer Res 58 1998 5466 5472
31. J.M. Pellikainen, V.M. Kosma Activator protein-2 in carcinogenesis with a special reference to breast cancer: a mini review Int J Cancer 120 2007 2061 2067
32. C.M. Koebel, W. Vermi, J.B. Swann, N. Zerafa, S.J. Rodig, L.J. Old, M.J. Smyth, R.D. Schreiber Adaptive immunity maintains occult cancer in an equilibrium state Nature 450 2007 903 907
33. A. Leask, C. Byrne, E. Fuchs Transcription factor AP2 and its role in epidermal-specific gene expression Proc Natl Acad Sci U S A 88 1991 7948 7952
34. F. Orso, E. Penna, D. Cimino, E. Astanina, F. Maione, D. Valdembri, E. Giraudo, G. Serini, P. Sismondi, M. De Bortoli, D. Taverna AP-2alpha and AP-2gamma regulate tumor progression via specific genetic programs FASEB J 22 2008 2702 2714
35. N. Friedrichs, R. Jager, E. Paggen, C. Rudlowski, S. Merkelbach-Bruse, H. Schorle, R. Buettner Distinct spatial expression patterns of AP-2alpha and AP-2gamma in non-neoplastic human breast and breast cancer Mod Pathol 18 2005 431 438
36. D. Vernimmen, D. Begon, C. Salvador, S. Gofflot, M. Grooteclaes, R. Winkler Identification of HTF (HER2 transcription factor) as an AP-2 (activator protein-2) transcription factor and contribution of the HTF binding site to ERBB2 gene overexpression Biochem J 370 2003 323 329
37. M. Ruiz, C. Pettaway, R. Song, O. Stoeltzing, L. Ellis, M. Bar-Eli Activator protein 2alpha inhibits tumorigenicity and represses vascular endothelial growth factor transcription in prostate cancer cells Cancer Res 64 2004 631 638
38. M.J. Smyth, J. Swann, E. Cretney, N. Zerafa, W.M. Yokoyama, Y. Hayakawa NKG2D function protects the host from tumor initiation J Exp Med 202 2005 583 588
39. D. Eckert, S. Buhl, S. Weber, R. Jager, H. Schorle The AP-2 family of transcription factors Genome Biol 6 2005 246
40. N. Oyama, K. Iwatsuki, Y. Homma, F. Kaneko Induction of transcription factor AP-2 by inflammatory cytokines in human keratinocytes J Invest Dermatol 113 1999 600 606
41. K. Suyama, Y. Kabuyama, S. Suzuki, Y. Kawasaki, J. Suzuki, H. Suzuki, Y. Homma Induction of transcription factor AP-2 by cytokines and prostaglandins in cultured mesangial cells Am J Nephrol 21 2001 307 314