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Volumn 27, Issue 2, 2012, Pages 319-330

Genome-wide association of an integrated osteoporosis-related phenotype: Is there evidence for pleiotropic genes?

Author keywords

BONE MINERAL DENSITY; FEMORAL GEOMETRY; GENOME WIDE ASSOCIATION; MUSCLE MASS; PLEIOTROPY; PRINCIPAL COMPONENT ANALYSIS; QUANTITATIVE ULTRASOUND; SINGLE NUCLEOTIDE POLYMORPHISMS

Indexed keywords

A KINASE ANCHOR PROTEIN 6; CYCLIC AMP DEPENDENT PROTEIN KINASE ANCHORING PROTEIN; SEROTONIN RECEPTOR; SEROTONIN RECEPTOR 1E; UNCLASSIFIED DRUG;

EID: 84862972320     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.563     Document Type: Article
Times cited : (19)

References (47)
  • 1
    • 33750209491 scopus 로고    scopus 로고
    • An estimate of the worldwide prevalence and disability associated with osteoporotic fractures
    • DOI 10.1007/s00198-006-0172-4
    • Johnell O, Kanis JA,. An estimate of the worldwide prevalence and disability associated with osteoporotic fractures. Osteoporos Int. 2006; 17 (12): 1726-33. (Pubitemid 44607392)
    • (2006) Osteoporosis International , vol.17 , Issue.12 , pp. 1726-1733
    • Johnell, O.1    Kanis, J.A.2
  • 3
    • 0032931920 scopus 로고    scopus 로고
    • How to use ultrasound for risk assessment: A need for defining strategies
    • DOI 10.1007/s001980050135
    • Gluer CC, Hans D,. How to use ultrasound for risk assessment: a need for defining strategies. Osteoporos Int. 1999; 9 (3): 193-5. (Pubitemid 29182367)
    • (1999) Osteoporosis International , vol.9 , Issue.3 , pp. 193-195
    • Gluer, C.-C.1    Hans, D.2
  • 4
    • 0029986509 scopus 로고    scopus 로고
    • Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures
    • Marshall D, Johnell O, Wedel H,. Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures. BMJ. 1999; 312 (7041): 1254-9.
    • (1999) BMJ , vol.312 , Issue.7041 , pp. 1254-1259
    • Marshall, D.1    Johnell, O.2    Wedel, H.3
  • 6
    • 0036378851 scopus 로고    scopus 로고
    • Evidence for a major gene for bone mineral density/content in human pedigrees identified via probands with extreme bone mineral density
    • Deng HW, Livshits G, Yakovenko K, Xu FH, Conway T, Davies KM, Deng H, Recker RR,. Evidence for a major gene for bone mineral density/content in human pedigrees identified via probands with extreme bone mineral density. Ann Hum Genet. 2002; 66 (Pt 1): 61-74.
    • (2002) Ann Hum Genet. , vol.66 , Issue.PART 1 , pp. 61-74
    • Deng, H.W.1    Livshits, G.2    Yakovenko, K.3    Xu, F.H.4    Conway, T.5    Davies, K.M.6    Deng, H.7    Recker, R.R.8
  • 8
    • 0031856655 scopus 로고    scopus 로고
    • Genetic and environmental contributions to the association between quantitative ultrasound and bone mineral density measurements: A twin study
    • DOI 10.1359/jbmr.1998.13.8.1318
    • Howard GM, Nguyen TV, Harris M, Kelly PJ, Eisman JA,. Genetic and environmental contributions to the association between quantitative ultrasound and bone mineral density measurements: a twin study. J Bone Miner Res. 1998; 13 (8): 1318-27. (Pubitemid 28373334)
    • (1998) Journal of Bone and Mineral Research , vol.13 , Issue.8 , pp. 1318-1327
    • Howard, G.M.1    Nguyen, T.V.2    Harris, M.3    Kelly, P.J.4    Eisman, J.A.5
  • 9
    • 0036078514 scopus 로고    scopus 로고
    • Genetic control of susceptibility to osteoporosis
    • DOI 10.1210/jc.87.6.2460
    • Ralston SH,. Genetic control of susceptibility to osteoporosis. J Clin Endocrinol Metab. 2002; 87 (6): 2460-6. (Pubitemid 34655301)
    • (2002) Journal of Clinical Endocrinology and Metabolism , vol.87 , Issue.6 , pp. 2460-2466
    • Ralston, S.H.1
  • 11
    • 40849096745 scopus 로고    scopus 로고
    • Thigh muscle attenuation is associated with incident hip fracture: The Health Aging and Body Composition (Health ABC) Study
    • Lang TF, Cauley J, Tylavsky F, Chen H, Harris TB,. Thigh muscle attenuation is associated with incident hip fracture: the Health Aging and Body Composition (Health ABC) Study. J Bone Miner Res. 2006; 21 (Suppl 1): S35.
    • (2006) J Bone Miner Res. , vol.21 , Issue.SUPPL. 1
    • Lang, T.F.1    Cauley, J.2    Tylavsky, F.3    Chen, H.4    Harris, T.B.5
  • 13
    • 65549137512 scopus 로고    scopus 로고
    • Bivariate genome-wide linkage analysis of femoral bone traits and leg lean mass: Framingham study
    • Karasik D, Zhou Y, Cupples LA, Hannan MT, Kiel DP, Demissie S,. Bivariate genome-wide linkage analysis of femoral bone traits and leg lean mass: Framingham study. J Bone Miner Res. 2009; 24 (4): 710-8.
    • (2009) J Bone Miner Res. , vol.24 , Issue.4 , pp. 710-718
    • Karasik, D.1    Zhou, Y.2    Cupples, L.A.3    Hannan, M.T.4    Kiel, D.P.5    Demissie, S.6
  • 14
    • 1542286077 scopus 로고    scopus 로고
    • Genome screen for a combined bone phenotype using principal component analysis: The Framingham study
    • DOI 10.1016/j.bone.2003.11.017, PII S8756328203004265
    • Karasik D, Cupples LA, Hannan MT, Kiel DP,. Genome screen for a combined bone phenotype using principal component analysis: the Framingham study. Bone. 2004; 34 (3): 547-56. (Pubitemid 38314919)
    • (2004) Bone , vol.34 , Issue.3 , pp. 547-556
    • Karasik, D.1    Cupples, L.A.2    Hannan, M.T.3    Kiel, D.P.4
  • 16
    • 79751523914 scopus 로고    scopus 로고
    • Linkage mapping of principal components for femoral biomechanical performance in a reciprocal HCB-8xHCB-23 intercross
    • Saless N, Litscher SJ, Vanderby R, Demant P, Blank RD,. Linkage mapping of principal components for femoral biomechanical performance in a reciprocal HCB-8xHCB-23 intercross. Bone. 2011; 48: 647-53.
    • (2011) Bone. , vol.48 , pp. 647-653
    • Saless, N.1    Litscher, S.J.2    Vanderby, R.3    Demant, P.4    Blank, R.D.5
  • 19
    • 18744422155 scopus 로고    scopus 로고
    • The modular era of functional genomics
    • Segal E, Kim SK,. The modular era of functional genomics. Genome Biol. 2003; 4 (5): 317.
    • (2003) Genome Biol. , vol.4 , Issue.5 , pp. 317
    • Segal, E.1    Kim, S.K.2
  • 21
    • 0036708162 scopus 로고    scopus 로고
    • Genome screen for quantitative trait loci contributing to normal variation in bone mineral density: The Framingham Study
    • Karasik D, Myers RH, Cupples LA, Hannan MT, Gagnon DR, Herbert A, Kiel DP,. Genome screen for quantitative trait loci contributing to normal variation in bone mineral density: the Framingham Study. J Bone Miner Res. 2002; 17 (9): 1718-27.
    • (2002) J Bone Miner Res. , vol.17 , Issue.9 , pp. 1718-1727
    • Karasik, D.1    Myers, R.H.2    Cupples, L.A.3    Hannan, M.T.4    Gagnon, D.R.5    Herbert, A.6    Kiel, D.P.7
  • 22
    • 0036821122 scopus 로고    scopus 로고
    • Mapping of quantitative ultrasound of the calcaneus bone to chromosome 1 by genome-wide linkage analysis
    • DOI 10.1007/s001980200110
    • Karasik D, Myers RH, Hannan MT, Gagnon D, McLean RR, Cupples LA, Kiel DP,. Mapping of quantitative ultrasound of the calcaneus bone to chromosome 1 by genome-wide linkage analysis. Osteoporos Int. 2002; 13 (10): 796-802. (Pubitemid 36336724)
    • (2002) Osteoporosis International , vol.13 , Issue.10 , pp. 796-802
    • Karasik, D.1    Myers, R.H.2    Hannan, M.T.3    Gagnon, D.4    McLean, R.R.5    Cupples, L.A.6    Kiel, D.P.7
  • 23
    • 33846602219 scopus 로고    scopus 로고
    • Proximal hip geometry is linked to several chromosomal regions: Genome-wide linkage results from the Framingham Osteoporosis Study
    • DOI 10.1016/j.bone.2006.09.020, PII S8756328206007393
    • Demissie S, Dupuis J, Cupples LA, Beck TJ, Kiel DP, Karasik D,. Proximal hip geometry is linked to several chromosomal regions: Genome-wide linkage results from the Framingham Osteoporosis Study. Bone. 2007; 40 (3): 743-50. (Pubitemid 46187216)
    • (2007) Bone , vol.40 , Issue.3 , pp. 743-750
    • Demissie, S.1    Dupuis, J.2    Cupples, L.A.3    Beck, T.J.4    Kiel, D.P.5    Karasik, D.6
  • 25
    • 20544434692 scopus 로고    scopus 로고
    • In vivo short-term precision of hip structure analysis variables in comparison with bone mineral density using paired dual-energy X-ray absorptiometry scans from multi-center clinical trials
    • DOI 10.1016/j.bone.2005.03.007, PII S8756328205000931
    • Khoo BC, Beck TJ, Qiao QH, Parakh P, Semanick L, Prince RL, Singer KP, Price RI,. In vivo short-term precision of hip structure analysis variables in comparison with bone mineral density using paired dual-energy X-ray absorptiometry scans from multi-center clinical trials. Bone. 2005; 37 (1): 112-21. (Pubitemid 40848424)
    • (2005) Bone , vol.37 , Issue.1 , pp. 112-121
    • Khoo, B.C.C.1    Beck, T.J.2    Qiao, Q.-H.3    Parakh, P.4    Semanick, L.5    Prince, R.L.6    Singer, K.P.7    Price, R.I.8
  • 26
    • 78649562591 scopus 로고    scopus 로고
    • Protective effect of high protein and calcium intake on the risk of hip fracture in the Framingham offspring cohort
    • Sahni S, Cupples LA, McLean RR, Tucker KL, Broe KE, Kiel DP, Hannan MT,. Protective effect of high protein and calcium intake on the risk of hip fracture in the Framingham offspring cohort. J Bone Miner Res. 2010; 25 (12): 2770-6.
    • (2010) J Bone Miner Res. , vol.25 , Issue.12 , pp. 2770-2776
    • Sahni, S.1    Cupples, L.A.2    McLean, R.R.3    Tucker, K.L.4    Broe, K.E.5    Kiel, D.P.6    Hannan, M.T.7
  • 27
    • 0018639203 scopus 로고
    • Some health benefits of physical activity. The Framingham study
    • DOI 10.1001/archinte.139.8.857
    • Kannel WB, Sorlie P,. Some health benefits of physical activity. The Framingham Study. Arch Intern Med. 1979; 139 (8): 857-61. (Pubitemid 10150839)
    • (1979) Archives of Internal Medicine , vol.139 , Issue.8 , pp. 857-861
    • Kannel, W.B.1    Sorlie, P.2
  • 28
    • 33746512512 scopus 로고    scopus 로고
    • Principal components analysis corrects for stratification in genome-wide association studies
    • DOI 10.1038/ng1847, PII NG1847
    • Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, Reich D,. Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet. 2006; 38 (8): 904-9. (Pubitemid 44141658)
    • (2006) Nature Genetics , vol.38 , Issue.8 , pp. 904-909
    • Price, A.L.1    Patterson, N.J.2    Plenge, R.M.3    Weinblatt, M.E.4    Shadick, N.A.5    Reich, D.6
  • 30
    • 0022649864 scopus 로고
    • The use of measured genotype information in the analysis of quantitative phenotypes in man
    • Boerwinkle E, Chakraborty R, Sing CF,. The use of measured genotype information in the analysis of quantitative phenotypes in man. I. Models and analytical methods. Ann Hum Genet. 1986; 50 (Pt 2): 181-94. (Pubitemid 16116788)
    • (1986) Annals of Human Genetics , vol.50 , Issue.2 , pp. 181-194
    • Boerwinkle, E.1    Chakraborty, R.2    Sing, C.F.3
  • 31
    • 58249124501 scopus 로고    scopus 로고
    • Establishing an adjusted p-value threshold to control the family-wide type 1 error in genome wide association studies
    • Duggal P, Gillanders EM, Holmes TN, Bailey-Wilson JE,. Establishing an adjusted p-value threshold to control the family-wide type 1 error in genome wide association studies. BMC Genomics. 2008; 9: 516.
    • (2008) BMC Genomics. , vol.9 , pp. 516
    • Duggal, P.1    Gillanders, E.M.2    Holmes, T.N.3    Bailey-Wilson, J.E.4
  • 32
    • 0035799707 scopus 로고    scopus 로고
    • Lethality and centrality in protein networks
    • DOI 10.1038/35075138
    • Jeong H, Mason SP, Barabasi AL, Oltvai ZN,. Lethality and centrality in protein networks. Nature. 2001; 411 (6833): 41-2. (Pubitemid 32428180)
    • (2001) Nature , vol.411 , Issue.6833 , pp. 41-42
    • Jeong, H.1    Mason, S.P.2    Barabasi, A.-L.3    Oltvai, Z.N.4
  • 36
    • 56049128119 scopus 로고    scopus 로고
    • Excitability of small-diameter trigeminal ganglion neurons by 5-HT is mediated by enhancement of the tetrodotoxin-resistant sodium current due to the activation of 5-HT(4) receptors and/or by the inhibition of the transient potassium current
    • Tsutsui Y, Ikeda M, Takeda M, Matsumoto S,. Excitability of small-diameter trigeminal ganglion neurons by 5-HT is mediated by enhancement of the tetrodotoxin-resistant sodium current due to the activation of 5-HT(4) receptors and/or by the inhibition of the transient potassium current. Neuroscience. 2008; 157 (3): 683-96.
    • (2008) Neuroscience. , vol.157 , Issue.3 , pp. 683-696
    • Tsutsui, Y.1    Ikeda, M.2    Takeda, M.3    Matsumoto, S.4
  • 37
    • 25644452031 scopus 로고    scopus 로고
    • The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways
    • DOI 10.1038/nature03966, PII N03966
    • Dodge-Kafka KL, Soughayer J, Pare GC, Carlisle Michel JJ, Langeberg LK, Kapiloff MS, Scott JD,. The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways. Nature. 2005; 437 (7058): 574-8. (Pubitemid 41613557)
    • (2005) Nature , vol.437 , Issue.7058 , pp. 574-578
    • Dodge-Kafka, K.L.1    Soughayer, J.2    Pare, G.C.3    Carlisle Michel, J.J.4    Langeberg, L.K.5    Kapiloff, M.S.6    Scott, J.D.7
  • 40
  • 42
    • 38149020685 scopus 로고    scopus 로고
    • Pleiotropy and principal components of heritability combine to increase power for association analysis
    • Klei L, Luca D, Devlin B, Roeder K,. Pleiotropy and principal components of heritability combine to increase power for association analysis. Genet Epidemiol. 2008; 32 (1): 9-19.
    • (2008) Genet Epidemiol. , vol.32 , Issue.1 , pp. 9-19
    • Klei, L.1    Luca, D.2    Devlin, B.3    Roeder, K.4
  • 44
    • 56749107611 scopus 로고    scopus 로고
    • Prediction of incident hip fracture risk by femur geometry variables measured by hip structural analysis in the study of osteoporotic fractures
    • Kaptoge S, Beck TJ, Reeve J, Stone KL, Hillier TA, Cauley JA, Cummings SR,. Prediction of incident hip fracture risk by femur geometry variables measured by hip structural analysis in the study of osteoporotic fractures. J Bone Miner Res. 2008; 23 (12): 1892-904.
    • (2008) J Bone Miner Res. , vol.23 , Issue.12 , pp. 1892-1904
    • Kaptoge, S.1    Beck, T.J.2    Reeve, J.3    Stone, K.L.4    Hillier, T.A.5    Cauley, J.A.6    Cummings, S.R.7
  • 45
    • 79958839788 scopus 로고    scopus 로고
    • Bayesian block clustering for multiple osteoporosis-related genome-wide association studies (GWAS)
    • Gupta M, Cheung CL, Hsu Y, Demissie S, Cupples LA, Kiel DP, Karasik D,. Bayesian block clustering for multiple osteoporosis-related genome-wide association studies (GWAS). J Bone Min Res. 2011; 26 (6): 1261-71.
    • (2011) J Bone Min Res. , vol.26 , Issue.6 , pp. 1261-1271
    • Gupta, M.1    Cheung, C.L.2    Hsu, Y.3    Demissie, S.4    Cupples, L.A.5    Kiel, D.P.6    Karasik, D.7
  • 46
    • 34548592030 scopus 로고    scopus 로고
    • Hip structural geometry in old and old-old age: Similarities and differences between men and women
    • DOI 10.1016/j.bone.2007.06.001, PII S8756328207005091
    • Yates LB, Karasik D, Beck TJ, Cupples LA, Kiel DP,. Hip structural geometry in old and old-old age: similarities and differences between men and women. Bone. 2007; 41 (4): 722-32. (Pubitemid 47393665)
    • (2007) Bone , vol.41 , Issue.4 , pp. 722-732
    • Yates, L.B.1    Karasik, D.2    Beck, T.J.3    Cupples, L.A.4    Kiel, D.P.5
  • 47
    • 34047269282 scopus 로고    scopus 로고
    • An application of bioinformatics and text mining to the discovery of novel genes related to bone biology
    • DOI 10.1016/j.bone.2006.12.067, PII S8756328206009471
    • Gajendran VK, Lin JR, Fyhrie DP,. An application of bioinformatics and text mining to the discovery of novel genes related to bone biology. Bone. 2007; 40 (5): 1378-88. (Pubitemid 46550977)
    • (2007) Bone , vol.40 , Issue.5 , pp. 1378-1388
    • Gajendran, V.K.1    Lin, J.-R.2    Fyhrie, D.P.3


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