2-Hydroxy-3-methylanthraquinone from Hedyotis diffusa WILLD Induces Apoptosis via Alteration of Fas/FasL and Activation of Caspase-8 in Human Leukemic THP-1 Cells

Archives of Medical Research

Volumn 42, Issue 7, 2011, Pages 577-583

  Wang, Jia he ^a   Shu, Lin hua ^a   Yang, Li li ^a   Zhang, Meng ^a   He, Ping ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

2 hydroxy 3 methylanthraquinone; Apoptosis; Fas; FasL; Hedyotis diffusa WILLD; THP 1

Indexed keywords

2 HYDROXY 3 METHYLANTHRAQUINONE; ANTHRAQUINONE DERIVATIVE; CASPASE 8; DEATH RECEPTOR 4; DEATH RECEPTOR 5; FAS ANTIGEN; FAS LIGAND; FLICE INHIBITORY PROTEIN; HEDYOTIS DIFFUSA EXTRACT; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG MECHANISM; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LEUKEMIA THP 1; PROTEIN EXPRESSION; PROTEIN FUNCTION; WESTERN BLOTTING;

ANTHRAQUINONES; ANTIGENS, CD95; APOPTOSIS; BLOTTING, WESTERN; CASPASE 8; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; FAS LIGAND PROTEIN; FLOW CYTOMETRY; HEDYOTIS; HUMANS; LEUKEMIA;

EID: 84862970415     PISSN: 01884409     EISSN: 18735487     Source Type: Journal    
DOI: 10.1016/j.arcmed.2011.11.003     Document Type: Article

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