6-Nitro-2-(3-hydroxypropyl)-1H-benz[de]isoquinoline-1,3-dione, a potent antitumor agent, induces cell cycle arrest and apoptosis

Journal of Experimental and Clinical Cancer Research

Volumn 29, Issue 1, 2010, Pages

  Mukherjee, Asama ^a   Dutta, Sushanta ^a   Shanmugavel, Muthiah ^b   Mondhe, Dilip M ^b   Sharma, Parduman R ^b   Singh, Shashank K ^b   Saxena, Ajit K ^b   Sanyal, Utpal ^a  

^a CHITTARANJAN NATIONAL CANCER INSTITUTE   (India)

^b CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

6 NITRO 2 (3 HYDROXYPROPYL) 1H BENZ[DE]ISOQUINOLINE 1,3 DIONE; ANTINEOPLASTIC AGENT; CAMPTOTHECIN; CASPASE 3; CASPASE 6; CISPLATIN; DOXORUBICIN; FLUORESCEIN ISOTHIOCYANATE; FLUOROURACIL; LIPOCORTIN 5; MITOMYCIN C; PACLITAXEL; STREPTOMYCIN; THYMIDINE; UNCLASSIFIED DRUG; URIDINE; NAPHTHALIMIDE DERIVATIVE;

ACUTE LYMPHOBLASTIC LEUKEMIA; APOPTOSIS; ARTICLE; BREAST CANCER; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE S PHASE; CELL STRAIN HL 60; CLINICAL EVALUATION; CLINICAL EXAMINATION; CONTROLLED STUDY; DAUGHTER CELL; DRUG ACCUMULATION; DRUG ACTIVITY; DRUG CONCENTRATION; DRUG CYTOTOXICITY; DRUG SCREENING; ENZYME ACTIVITY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MITOSIS INHIBITION; MORPHOLOGY; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; TRANSMISSION ELECTRON MICROSCOPY; TUMOR CELL LINE; UPREGULATION; CELL CYCLE; DRUG EFFECT;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; NAPHTHALIMIDES;

EID: 78650658236     PISSN: None     EISSN: 17569966     Source Type: Journal    
DOI: 10.1186/1756-9966-29-175     Document Type: Article

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