Structural basis for the recognition of C20:2-αGalCer by the invariant natural killer T cell receptor-like antibody L363

Journal of Biological Chemistry

Volumn 287, Issue 2, 2012, Pages 1269-1278

  Yu, Esther Dawen ^a   Girardi, Enrico ^a   Wang, Jing ^a   Mac, Thien Thi ^a   Yu, Karl O A ^b,d   Van Calenbergh, Serge ^c   Porcelli, Steven A ^b   Zajonc, Dirk M ^a  

^a LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c GHENT UNIVERSITY   (Belgium)

^d UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANOMERICS; CELL ACTIVATION; GLYCO LIPIDS; GLYCOSPHINGOLIPIDS; GLYCOSYL; NATURAL KILLER T CELL; STRUCTURAL BASIS; STRUCTURAL CHANGE; T-CELL RECEPTORS;

ANTIGENS; CELL MEMBRANES; CRYSTAL STRUCTURE;

ANTIBODIES;

1 O (ALPHA GALACTOPYRANOSYL) 2 HEXACOSANOYLAMINO 1,3,4 OCTADECANETRIOL; ALPHA GALACTOSYLCERAMIDE; CD1D ANTIGEN; CELL ANTIBODY; GLYCOLIPID; IMMUNOGLOBULIN F(AB) FRAGMENT; L 363 ANTIBODY; UNCLASSIFIED DRUG;

ANTIGEN BINDING; ANTIGEN EXPRESSION; ANTIGEN SPECIFICITY; ARTICLE; BINDING KINETICS; CELL ACTIVATION; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; HUMAN; HUMAN CELL; MOLECULAR RECOGNITION; NATURAL KILLER T CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL, MURINE-DERIVED; ANTIBODY SPECIFICITY; ANTIGENS, CD1D; CRYSTALLOGRAPHY, X-RAY; GALACTOSYLCERAMIDES; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; MICE; MOLECULAR SEQUENCE DATA; NATURAL KILLER T-CELLS; PROTEIN STRUCTURE, QUATERNARY; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA;

EID: 84862936210     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.308783     Document Type: Article

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