Up-regulated autophagy by endogenous high mobility group box-1 promotes chemoresistance in leukemia cells

Leukemia and Lymphoma

Volumn 53, Issue 2, 2012, Pages 315-322

  Yang, Liangchun ^a   Yu, Yan ^a   Kang, Rui ^a,b   Yang, Minghua ^a   Xie, Min ^a   Wang, Zhuo ^a   Tang, Daolin ^b   Zhao, Mingyi ^a   Liu, Liying ^a   Zhang, Hong ^a   Cao, Lizhi ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

Author keywords

Autophagy; Drug resistance; HMGB1; Leukemia; MTOR; PI3K

Indexed keywords

3 METHYLADENINE; CYTARABINE; DOXORUBICIN; HIGH MOBILITY GROUP B1 PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN; PROTEIN KINASE B; PROTEIN RAPTOR; S6 KINASE; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; VINCRISTINE;

ARTICLE; AUTOPHAGY; CANCER CELL CULTURE; CANCER RESISTANCE; CELL VIABILITY; CHILDHOOD LEUKEMIA; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG SENSITIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LEUKEMIA CELL; PRIORITY JOURNAL; UPREGULATION;

ADENINE; AUTOPHAGY; BLOTTING, WESTERN; CELL PROLIFERATION; CELLS, CULTURED; CHILD; DRUG RESISTANCE, NEOPLASM; HMGB1 PROTEIN; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; IMMUNOPRECIPITATION; LEUKEMIA; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; TOR SERINE-THREONINE KINASES; UP-REGULATION;

EID: 84862908645     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.3109/10428194.2011.616962     Document Type: Article

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