Structure of the stapled p53 peptide bound to Mdm2

Journal of the American Chemical Society

Volumn 134, Issue 1, 2012, Pages 103-106

  Baek, Sohee ^a,f   Kutchukian, Peter S ^b   Verdine, Gregory L ^b   Huber, Robert ^a,c,d,e   Holak, Tad A ^a,g   Lee, Ki Won ^f   Popowicz, Grzegorz M ^a  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^b HARVARD UNIVERSITY   (United States)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^d CARDIFF UNIVERSITY   (United Kingdom)

^e UNIVERSITY OF DUISBURG ESSEN   (Germany)

^f Seoul National University   (South Korea)

^g JAGIELLONIAN UNIVERSITY   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-CANCER AGENTS; BINDING INTERFACE; HUMAN CANCER; MODE OF ACTION; NEGATIVE REGULATORS; P53 PROTEIN; PROTEIN-PROTEIN INTERACTIONS; RESOLUTION STRUCTURE; THERAPEUTIC POTENTIALS; TUMOR SUPPRESSORS;

HYDROCARBONS; PEPTIDES;

CRYSTAL STRUCTURE;

HYDROCARBON; PROTEIN MDM2; PROTEIN P53;

ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; MOLECULAR STABILITY; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TARGETING;

AMINO ACID SEQUENCE; CRYSTALLOGRAPHY, X-RAY; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTO-ONCOGENE PROTEINS C-MDM2; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84862908454     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja2090367     Document Type: Article

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