Matrix metalloproteinases 15 and 19 are stromal regulators of colorectal cancer development from the early stages

International Journal of Oncology

Volumn 41, Issue 1, 2012, Pages 260-266

  Sena, Paola ^a   Mariani, Francesco ^a   Marzona, Laura ^a   Benincasa, Marta ^a   Ponz De Leon, Maurizio ^a   Palumbo, Carla ^a   Roncucci, Luca ^a  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

Human colorectal carcinogenesis; Immunofluorescence; Matrix metalloproteinases; Microadenomas; qPCR

Indexed keywords

MATRIX METALLOPROTEINASE 15; MATRIX METALLOPROTEINASE 19; MESSENGER RNA;

ARTICLE; COLON CARCINOGENESIS; COLON MUCOSA; COLORECTAL CARCINOMA; CONFOCAL MICROSCOPY; CONTROLLED STUDY; EARLY CANCER; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; MALIGNANT TRANSFORMATION; MICROADENOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS; RECTUM MUCOSA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STROMA; UPREGULATION; WESTERN BLOTTING;

ADENOMA; CARCINOMA; CELL TRANSFORMATION, NEOPLASTIC; COLORECTAL NEOPLASMS; EPITHELIAL CELLS; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MATRIX METALLOPROTEINASE 15; MATRIX METALLOPROTEINASES, SECRETED; MICROSCOPY, CONFOCAL; TRANSCRIPTION, GENETIC;

EID: 84862905776     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2012.1441     Document Type: Article

References (34)

1. Kalebic T, Garbisa S, Glaser B and Lotta LA: Basement membrane collagen: degradation by migrating endothelial cells. Science 221: 281-283, 1983. (Pubitemid 13062622)
2. Sato H, Takino T, Okada Y, Cao J, Shinagawa A, Yamamoto E and Seiki M: Matrix metalloproteinase expressed on the surface of invasive tumour cells. Nature 370: 61-65, 1994. (Pubitemid 24216953)
3. Coussens LM, Fingleton B and Matrisian LM: Matrix metalloproteinase inhibitors and cancer: trials and tribulations. Science 29: 2387-2392, 2002. (Pubitemid 34270240)
4. Takino T, Sato H, Shinagawa A and Seiki M: Identification of the second membrane-type matrix metalloproteinase (MT-MMP-2) gene from a human placenta cDNA library. MT-MMPs form a unique membrane-type subclass in the MMP family. J Biol Chem 29: 23013-23020, 1995.
5. Sato H: Membrane-type matrix metalloproteinases (MT-MMPs) in tumour metastasis. J Biochem 119: 209-215, 1996.
6. d'Ortho MP, Will H, Atkinson S, Butler G, Messent A, Gavrilovic J, Smith B, Timpl R, Zardi L and Murphy G: Membrane-type matrix metalloproteinases 1 and 2 exhibit broad-spectrum proteolytic capacities comparable to many matrix metalloproteinases. Eur J Biochem 250: 751-757, 1997. (Pubitemid 28022492)
7. English WR, Puente XS, Freije JM, Knauper V, Amour A, Merryweather A, Lopez-Otin C and Murphy G: Membrane type 4 matrix metalloproteinase (MMP17) has tumour necrosis factor-alpha convertase activity but does not activate pro-MMP2. J Biol Chem 275: 14046-14055, 2000. (Pubitemid 30339678)
8. Szabova L, Yamada SS, Birkedal-Hansen H and Holmbeck K: Expression pattern of four membrane-type matrix metalloproteinases in the normal and diseased mouse mammary gland. J Cell Physiol 205: 123-132, 2005. (Pubitemid 41262858)
9. Hotary K, Allen E, Punturieri A, Yana I and Weiss SJ: Regulation of cell invasion and morphogenesis in a three-dimensional type I collagen matrix by membrane-type matrix metalloproteinases 1, 2, and 3. J Cell Biol 149: 1309-1323, 2000. (Pubitemid 30399683)
10. Holmbeck K, Bianco P, Yamada S and Birkedal-Hansen H: MT1-MMP: A tethered collagenase. J Cell Physiol 200: 11-19, 2004. (Pubitemid 38720617)
11. Ueno H, Nakamura H, Inoue M, Imai K, Noguchi M, Sato H, Seiki M and Okada Y: Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human invasive breast carcinomas. Cancer Res 57: 2055-2060, 1997. (Pubitemid 27209741)
12. Davidson B, Goldberg I, Berner A, Nesland JM, Givant-Horwitz V, Bryne M, Risberg B, Kristensen GB, Tropé CG, Kopolovic J and Reich R: Expression of membrane-type 1, 2, and 3 matrix metalloproteinases messenger RNA in ovarian carcinoma cells in serous effusions. Am J Clin Pathol 115: 517-524, 2001. (Pubitemid 32275943)
13. Ito E, Yana I, Fujita C, Irifune A, Takeda M, Madachi A, Mori S, Hamada Y, Kawaguchi N and Matsuura N: The role of MT2-MMP in cancer progression. Biochem Biophys Res Commun 393: 222-227, 2010.
14. Abraham R, Schafer J, Rothe M, Bange J, Knyazev P and Ullrich A: Identification of MMP-15 as an anti-apoptotic factor in cancer cells. J Biol Chem 280: 34123-34132, 2005. (Pubitemid 41443136)
15. Asano T, Tada M, Cheng S, Takemoto N, Kuramae T, Abe M, Takahashi O, Miyamoto M, Hamada J, Moriuchi T and Kondo S: Prognostic values of matrix metalloproteinase family expression in human colorectal carcinoma. J Surg Res 146: 32-42, 2008. (Pubitemid 351442927)
16. Sedlacek R, Mauch S, Kolb B, Schätzlein C, Eibel H, Peter HH, Schmitt J and Krawinkel U: Matrix metalloproteinase MMP-19 (RASI-1) is expressed on the surface of activated peripheral blood mononuclear cells and is detected as an autoantigen in rheumatoid arthritis. Immunobiology 198: 408-423, 1998. (Pubitemid 28098486)
17. Lettau I, Hattermann K, Held-Feindt J, Brauer R, Sedlacek R and Mentlein R: Matrix metalloproteinase-19 is highly expressed in astroglial tumours and promotes invasion of glioma cells. Neuropathol Exp Neurol 69: 215-223, 2010.
18. Müller M, Beck IM, Gadesmann J, Karschuk N, Paschen A, Proksch E, Djonov V, Reiss K and Sedlacek R: MP19 is upregulated during melanoma progression and increases invasion of melanoma cells. Mod Pathol 23: 511-521, 2010.
19. Sadowski T, Dietrich S, Koschinsky F and Sedlacek R: Matrix metalloproteinase 19 regulates insulin-like growth factor-mediated proliferation, migration, and adhesion in human keratinocytes through proteolysis of insulin-like growth factor binding protein-3. Mol Biol Cell 14: 4569-4580, 2003. (Pubitemid 37444656)
20. Djonov V, Högger K, Sedlacek R, Laissue J and Draeger A: MMP-19: cellular localization of a novel metalloproteinase within normal breast tissue and mammary gland tumours. J Pathol 195: 147-155, 2001. (Pubitemid 32899022)
21. Impola U, Toriseva M, Suomela S, Jeskanen L, Hieta N, Jahkola T, Grenman R, Kähäri VM and Saarialho-Kere U: Matrix metalloproteinase-19 is expressed by proliferating epithelium but disappears with neoplastic dedifferentiation. Int J Cancer 103: 709-716, 2003. (Pubitemid 36110225)
22. Bister VO, Salmela MT, Karjalainen-Lindsberg ML, Uria J, Lohi J, Puolakkainen P, Lopez-Otin C and Saarialho-Kere U: Differential expression of three matrix metalloproteinases, MMP-19, MMP-26, and MMP-28, in normal and inflamed intestine and colon cancer. Dig Dis Sci 49: 653-661, 2004. (Pubitemid 38992558)
23. Sena P, Roncucci L, Marzona L, Mariani F, Maffei S, Manenti A and De Pol A: Altered expression of apoptosis biomarkers in human colorectal microadenomas. Cancer Epidemiol Biomarkers Prev 19: 351-357, 2010.
24. Livak KJ and Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25: 402-408, 2001. (Pubitemid 34164012)
25. Li XY, Ota I, Yana I, Sabeh F and Weiss SJ: Molecular dissection of the structural machinery underlying the tissue-invasive activity of membrane type-1 matrix metalloproteinase. Mol Biol Cell 19: 3221-3233, 2008.
26. Ougolkov AV, Yamashita K, Mai M and Minamoto T: Oncogenic beta-catenin and MMP-7 (matrilysin) cosegregate in late-stage clinical colon cancer. Gastroenterology 122: 60-71, 2002. (Pubitemid 34049195)
27. Bousserouel S, Kauntz H, Gossé F, Bouhadjar M, Soler L, Marescaux J and Raul F: Identification of gene expression profiles correlated to tumour progression in a preclinical model of colon carcinogenesis. Int J Oncol 36: 1485-1490, 2010.
28. Mauch S, Kolb C, Kolb B, Sadowski T and Sedlacek R: Matrix metalloproteinase-19 is expressed in myeloid cells in an adhesion-dependent manner and associates with the cell surface. J Immunol 168: 1244-1251, 2002. (Pubitemid 34094491)
29. Hieta N, Impola U, López-Otín C, Saarialho-Kere U and Kähäri VM: Matrix metalloproteinase-19 expression in dermal wounds and by fibroblasts in culture. J Invest Dermatol 121: 997-1004, 2003. (Pubitemid 37430965)
30. Kuperwasser C, Chavarria T, Wu M, Magrane G, Gray JW, Carey L, Richardson A and Weinberg RA: Reconstruction of functionally normal and malignant human breast tissues in mice. Proc Natl Acad Sci USA 101: 4966-4971, 2004. (Pubitemid 38469186)
31. Kalluri R: Basement membranes: structure, assembly and role in tumour angiogenesis. Nat Rev Cancer 3: 422-433, 2003.
32. Liotta LA and Kohn EC: The microenvironment of the tumour-host interface. Nature 411: 375-379, 2001.
33. Lynch CC and Matrisian LM: Matrix metalloproteinases in tumour-host cell communication. Differentiation 70: 561-573, 2002. (Pubitemid 36194320)
34. Ko K, Yazumi S, Yoshikawa K, Konda Y, Nakajima M, Chiba T and Takahashi R: Activation of fibroblast-derived matrix metalloproteinase-2 by colon-cancer cells in non-contact co-cultures. Int J Cancer 87: 165-171, 2000. (Pubitemid 30434340)