Three sensitive assays do not provide evidence for circulating HuD-specific T cells in the blood of patients with paraneoplastic neurological syndromes with anti-Hu antibodies

Neuro-Oncology

Volumn 14, Issue 7, 2012, Pages 841-848

  De Jongste, Adriaan H C ^a   De Graaf, Marieke T ^a   Martinuzzi, Emanuela ^b,c,d   Van Den Broek, Patricia D M ^a   Kraan, Jaco ^a   Lamers, Cor H J ^a   Mallone, Roberto ^b,c,d   Gratama, Jan W ^a   Smitt, Peter A E Sillevis ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b INSERM   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d HÔTEL DIEU   (France)

Author keywords

anti Hu; CD8 + T cell; HuD specific T cell; immune response; paraneoplastic neurological syndrome

Indexed keywords

GAMMA INTERFERON; HU ANTIBODY; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; TETRAMER;

ADULT; AGED; ANTIBODY BLOOD LEVEL; ANTIBODY DETECTION; ANTIBODY TITER; ARTICLE; CELL CULTURE; CELL STIMULATION; CLINICAL ARTICLE; CYTOKINE PRODUCTION; DENDRITIC CELL; ENZYME LINKED IMMUNOSPOT ASSAY; FEMALE; FLOW CYTOMETRIC MULTIPLEX BEAD ARRAY; HUMAN; HUMAN CELL; MALE; PARANEOPLASTIC NEUROPATHY; T LYMPHOCYTE; TETRAMER STAINING;

AGED; ANTIBODIES, ANTI-IDIOTYPIC; BIOLOGICAL ASSAY; CASE-CONTROL STUDIES; CD8-POSITIVE T-LYMPHOCYTES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HU PARANEOPLASTIC ENCEPHALOMYELITIS ANTIGENS; HUMANS; INTERFERON-GAMMA; LEUKOCYTES, MONONUCLEAR; MALE; MIDDLE AGED; PARANEOPLASTIC SYNDROMES, NERVOUS SYSTEM; PEPTIDE FRAGMENTS; T-LYMPHOCYTE SUBSETS;

EID: 84862886443     PISSN: 15228517     EISSN: 15235866     Source Type: Journal    
DOI: 10.1093/neuonc/nos118     Document Type: Article

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