-
1
-
-
34249736779
-
Caenorhabditis elegans: A versatile platform for drug discovery
-
Artal-Sanz, M., de Jong, L., Tavernarakis, N. (2006). Caenorhabditis elegans: a versatile platform for drug discovery. Biotechnol J 1:1405-1418.
-
(2006)
Biotechnol J
, vol.1
, pp. 1405-1418
-
-
Artal-Sanz, M.1
De Jong, L.2
Tavernarakis, N.3
-
2
-
-
56749131234
-
Synthesis and antibiofilm activity of a second-generation reverse-amide oroidin library: A structure-activity relationship study
-
Ballard, T. E., Richards, J. J., Wolfe, A. L., Melander, C. (2008). Synthesis and antibiofilm activity of a second-generation reverse-amide oroidin library: a structure-activity relationship study. Chem Eur J 14:10745-10761.
-
(2008)
Chem Eur J
, vol.14
, pp. 10745-10761
-
-
Ballard, T.E.1
Richards, J.J.2
Wolfe, A.L.3
Melander, C.4
-
3
-
-
15044362347
-
Bromoageliferin and dibromoageliferin, secondary metabolites from the marine sponge Agelas conifera, inhibit voltage-operated, but not store-operated calcium entry in PC12 cells
-
Bickmeyer, U. (2005). Bromoageliferin and dibromoageliferin, secondary metabolites from the marine sponge Agelas conifera, inhibit voltage-operated, but not store-operated calcium entry in PC12 cells. Toxicon 45:627-632.
-
(2005)
Toxicon
, vol.45
, pp. 627-632
-
-
Bickmeyer, U.1
-
4
-
-
0023852747
-
Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line
-
Boukamp, P., Petrussevska, R. T., Breitkreutz, D., Hornung, J., Markham, A., Fusenig, N. E. (1988). Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. J Cell Biol 106:761-771. (Pubitemid 18089976)
-
(1988)
Journal of Cell Biology
, vol.106
, Issue.3
, pp. 761-771
-
-
Boukamp, P.1
Petrussevska, R.T.2
Breitkreutz, D.3
Hornung, J.4
Markham, A.5
Fusenig, N.E.6
-
5
-
-
77952772868
-
A high-throughput method for assessing chemical toxicity using a Caenorhabditis elegans reproduction assay
-
Boyd, W. A., McBride, S. J., Rice, J. R., Snyder, D. W., Freedman, J. H. (2010). A high-throughput method for assessing chemical toxicity using a Caenorhabditis elegans reproduction assay. Toxicol Appl Pharmacol 245:153-159.
-
(2010)
Toxicol Appl Pharmacol
, vol.245
, pp. 153-159
-
-
Boyd, W.A.1
McBride, S.J.2
Rice, J.R.3
Snyder, D.W.4
Freedman, J.H.5
-
6
-
-
0016063911
-
The genetics of Caenorhabditis elegans
-
Brenner, S. (1974). The genetics of Caenorhabditis elegans. Genetics 77:71-94.
-
(1974)
Genetics
, vol.77
, pp. 71-94
-
-
Brenner, S.1
-
7
-
-
34248684100
-
High-throughput screening of small molecules for bioactivity and target identification in Caenorhabditis elegans
-
DOI 10.1038/nprot.2006.283, PII NPROT.2006.283
-
Burns, A. R., Kwok, T. C. Y., Howard, A., Houston, E., Johanson, K., Chan, A., et al. (2006). High-throughput screening of small molecules for bioactivity and target identification in Caenorhabditis elegans. Nat Protocols 1:1906-1914. (Pubitemid 46773310)
-
(2006)
Nature Protocols
, vol.1
, Issue.4
, pp. 1906-1914
-
-
Burns, A.R.1
Kwok, T.C.Y.2
Howard, A.3
Houston, E.4
Johanson, K.5
Chan, A.6
Cutler, S.R.7
McCourt, P.8
Roy, P.J.9
-
8
-
-
0033591467
-
Bacterial biofilms: A common cause of persistent infections
-
DOI 10.1126/science.284.5418.1318
-
Costerton, J. W., Stewart, P. S., Greenberg, E. P. (1999). Bacterial biofilms: a common cause of persistent infections. Science 284:1318-1322. (Pubitemid 29289651)
-
(1999)
Science
, vol.284
, Issue.5418
, pp. 1318-1322
-
-
Costerton, J.W.1
Stewart, P.S.2
Greenberg, E.P.3
-
9
-
-
0348230977
-
The application of biofilm science to the study and control of chronic bacterial infections
-
DOI 10.1172/JCI200320365
-
Costerton, W., Veeh, R., Shirtliff, M., Pasmore, M., Post, C., Ehrlich, G. (2003). The application of biofilm science to the study and control of chronic bacterial infections. J Clin Invest 112:1466-1477. (Pubitemid 38056271)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.10
, pp. 1466-1477
-
-
Costerton, W.1
Veeh, R.2
Shirtliff, M.3
Pasmore, M.4
Post, C.5
Ehrlich, G.6
-
10
-
-
0037313237
-
Understanding biofilm resistance to antibacterial agents
-
Davies, D. (2003). Understanding biofilm resistance to antibacterial agents. Nat Rev Drug Discov 2:114-122.
-
(2003)
Nat Rev Drug Discov
, vol.2
, pp. 114-122
-
-
Davies, D.1
-
11
-
-
0022445670
-
Rapid colorimetric assay for cell growth and survival - Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability
-
DOI 10.1016/0022-1759(86)90368-6
-
Denizot, F., Lang, R. (1986). Rapid colorimetric assay for cell growth and survival: modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. J Immunol Methods 89:271-277. (Pubitemid 16080782)
-
(1986)
Journal of Immunological Methods
, vol.89
, Issue.2
, pp. 271-277
-
-
Denizot, F.1
Lang, R.2
-
12
-
-
0036228505
-
Biofilms: Survival mechanisms of clinically relevant microorganisms
-
DOI 10.1128/CMR.15.2.167-193.2002
-
Donlan, R. M., Costerton, J. W. (2002). Biofilms: survival mechanisms of clinically relevant microorganisms. Clin Microbiol Rev 15: 167-193. (Pubitemid 34303762)
-
(2002)
Clinical Microbiology Reviews
, vol.15
, Issue.2
, pp. 167-193
-
-
Donlan, R.M.1
Costerton, J.W.2
-
13
-
-
77954515025
-
Evaluation of a range of anti-proliferative assays for the preclinical screening of anti-psoriatic drugs: A comparison of colorimetric and fluorimetric assays with the thymidine incorporation assay
-
George, S. E., Anderson, R. J., Cunningham, A., Donaldson, M., Groundwater, P. W. (2010). Evaluation of a range of anti-proliferative assays for the preclinical screening of anti-psoriatic drugs: a comparison of colorimetric and fluorimetric assays with the thymidine incorporation assay. Assay Drug Dev Technol 8:384-395.
-
(2010)
Assay Drug Dev Technol
, vol.8
, pp. 384-395
-
-
George, S.E.1
Anderson, R.J.2
Cunningham, A.3
Donaldson, M.4
Groundwater, P.W.5
-
14
-
-
78449307290
-
Evaluation of toxic side effects of clinically used skin antiseptics in vitro
-
Hirsch, T., Koerber, A., Jacobsen, F., Dissemond, J., Steinau, H.-U., Gatermann, S., et al. (2009). Evaluation of toxic side effects of clinically used skin antiseptics in vitro. J Surg Res 164:344-350.
-
(2009)
J Surg Res
, vol.164
, pp. 344-350
-
-
Hirsch, T.1
Koerber, A.2
Jacobsen, F.3
Dissemond, J.4
Steinau, H.-U.5
Gatermann, S.6
-
16
-
-
43949132108
-
Control of bacterial biofilms with marine alkaloid derivatives
-
DOI 10.1039/b719989a
-
Huigens, R. W., III, Ma, L., Gambino, C., Moeller, P. D. R., Basso, A., Cavanagh, J., et al. (2008). Control of bacterial biofilms with marine alkaloid derivatives. Mol BioSyst 4:614-621. (Pubitemid 351706305)
-
(2008)
Molecular BioSystems
, vol.4
, Issue.6
, pp. 614-621
-
-
Huigens III, R.W.1
Ma, L.2
Gambino, C.3
Moeller, P.D.R.4
Basso, A.5
Cavanagh, J.6
Wozniak, D.J.7
Melander, C.8
-
17
-
-
34250184639
-
Inhibition of Pseudomonas aeruginosa biofilm formation with bromoageliferin analogues
-
DOI 10.1021/ja069017t
-
Huigens, R. W., Richards, J. J., Parise, G., Ballard, T. E., Zeng, W., Deora, R., et al. (2007). Inhibition of Pseudomonas aeruginosa biofilm formation with bromoageliferin analogues. J Am Chem Soc 129:6966-6967. (Pubitemid 46903240)
-
(2007)
Journal of the American Chemical Society
, vol.129
, Issue.22
, pp. 6966-6967
-
-
Huigens III, R.W.1
Richards, J.J.2
Parise, G.3
Ballard, T.E.4
Zeng, W.5
Deora, R.6
Melander, C.7
-
18
-
-
33745223646
-
Finding function in novel targets: C. elegans as a model organism
-
DOI 10.1038/nrd2031, PII N2031
-
Kaletta, T., Hengartner, M. O. (2006). Finding function in novel targets: C. elegans as a model organism. Nat Rev Drug Discov 5:387-399. (Pubitemid 43904931)
-
(2006)
Nature Reviews Drug Discovery
, vol.5
, Issue.5
, pp. 387-399
-
-
Kaletta, T.1
Hengartner, M.O.2
-
19
-
-
33646933785
-
A small-molecule screen in C. elegans yields a new calcium channel antagonist
-
Kwok, T. C. Y., Ricker, N., Fraser, R., Chan, A. W., Burns, A., Stanley, E. F., et al. (2006). A small-molecule screen in C. elegans yields a new calcium channel antagonist. Nature 441:91-95.
-
(2006)
Nature
, vol.441
, pp. 91-95
-
-
Kwok, T.C.Y.1
Ricker, N.2
Fraser, R.3
Chan, A.W.4
Burns, A.5
Stanley, E.F.6
-
20
-
-
54449099444
-
Caenorhabditis elegans: An emerging model in biomedical and environmental toxicology
-
Leung, M. C. K., Williams, P. L., Benedetto, A., Au, C., Helmcke, K. J., Aschner, M., et al. (2008). Caenorhabditis elegans: an emerging model in biomedical and environmental toxicology. Toxicol Sci 106:5-28.
-
(2008)
Toxicol Sci
, vol.106
, pp. 5-28
-
-
Leung, M.C.K.1
Williams, P.L.2
Benedetto, A.3
Au, C.4
Helmcke, K.J.5
Aschner, M.6
-
21
-
-
0029438537
-
Basic culture methods
-
Epstein, H., Shakes, D. (Eds.), San Diego, California, USA: Academic
-
Lewis, J. A., Fleming, J. T. (1995). Basic culture methods. In: Epstein, H., Shakes, D. (Eds.), Methods in cell biology (pp. 3-29). San Diego, California, USA: Academic.
-
(1995)
Methods in Cell Biology
, pp. 3-29
-
-
Lewis, J.A.1
Fleming, J.T.2
-
22
-
-
77956667483
-
New antibiotic agents and approaches to treat biofilm-associated infections
-
Lynch, A. S., Abbanat, D. (2010). New antibiotic agents and approaches to treat biofilm-associated infections. Expert Opin Ther Pat 20:1373-1387.
-
(2010)
Expert Opin Ther Pat
, vol.20
, pp. 1373-1387
-
-
Lynch, A.S.1
Abbanat, D.2
-
23
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
-
Mosmann, T. (1983). Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65:55-63.
-
(1983)
J Immunol Methods
, vol.65
, pp. 55-63
-
-
Mosmann, T.1
-
24
-
-
40549144848
-
Potential anthelmintics: Polyphenols from the tea plant Camellia sinensis L. are lethally toxic to Caenorhabditis elegans
-
Mukai, D., Matsuda, N., Yoshioka, Y., Sato, M., Yamasaki, T. (2008). Potential anthelmintics: polyphenols from the tea plant Camellia sinensis L. are lethally toxic to Caenorhabditis elegans. J Nat Med 62:155-159.
-
(2008)
J Nat Med
, vol.62
, pp. 155-159
-
-
Mukai, D.1
Matsuda, N.2
Yoshioka, Y.3
Sato, M.4
Yamasaki, T.5
-
25
-
-
33746521142
-
Chemical countermeasures for the control of bacterial biofilms: Effective compounds and promising targets
-
Musk, D. J., Jr., and Hergenrother, P. J. (2006). Chemical countermeasures for the control of bacterial biofilms: effective compounds and promising targets. Curr Med Chem 13:2163-2177.
-
(2006)
Curr Med Chem
, vol.13
, pp. 2163-2177
-
-
Musk Jr., D.J.1
Hergenrother, P.J.2
-
27
-
-
9444230640
-
The life and times of ivermectin - A success story
-
DOI 10.1038/nrmicro1048
-
Omura, S., Crump, A. (2004). The life and times of ivermectin-a success story. Nat Rev Micro 2:984-989. (Pubitemid 39562537)
-
(2004)
Nature Reviews Microbiology
, vol.2
, Issue.12
, pp. 984-989
-
-
Omura, S.1
Crump, A.2
-
28
-
-
85057694249
-
-
Boca Raton, Florida, USA: CRC
-
Pace, J. L., Rupp, M. E., Finch, R. G. (Eds.). (2006). Biofilms, infection, and antimicrobial therapy. Boca Raton, Florida, USA: CRC.
-
(2006)
Biofilms, Infection, and Antimicrobial Therapy
-
-
Pace, J.L.1
Rupp, M.E.2
Finch, R.G.3
-
29
-
-
0242523776
-
Bacterial Biofilms: An Emerging Link to Disease Pathogenesis
-
DOI 10.1146/annurev.micro.57.030502.090720
-
Parsek, M. R., Singh, P. K. (2003). Bacterial biofilms: an emerging link to disease pathogenesis. Annu Rev Microbiol 57:677-701. (Pubitemid 37392958)
-
(2003)
Annual Review of Microbiology
, vol.57
, pp. 677-701
-
-
Parsek, M.R.1
Singh, P.K.2
-
30
-
-
0026472940
-
In vitro cultured human skin cells as alternatives to animals for skin irritancy screening
-
Ponec, M. (1992). In vitro cultured human skin cells as alternatives to animals for skin irritancy screening. Int J Cosmet Sci 14:245-264.
-
(1992)
Int J Cosmet Sci
, vol.14
, pp. 245-264
-
-
Ponec, M.1
-
31
-
-
49249135187
-
Synthesis and screening of an oroidin library against Pseudomonas aeruginosa biofilms
-
Richards, J. J., Ballard, T. E., Huigens, R. W., Melander, C. (2008a). Synthesis and screening of an oroidin library against Pseudomonas aeruginosa biofilms. ChemBioChem 9:1267-1279.
-
(2008)
ChemBioChem
, vol.9
, pp. 1267-1279
-
-
Richards, J.J.1
Ballard, T.E.2
Huigens, R.W.3
Melander, C.4
-
32
-
-
41149142932
-
Inhibition and dispersion of proteobacterial biofilms
-
DOI 10.1039/b719802g
-
Richards, J. J., Huigens, R. W., III, Ballard, T. E., Basso, A., Cavanagh, J., Melander, C. (2008b). Inhibition and dispersion of proteobacterial biofilms. Chem Commun 1698-1700. (Pubitemid 351441911)
-
(2008)
Chemical Communications
, Issue.14
, pp. 1698-1700
-
-
Richards, J.J.1
Huigens III, R.W.2
Ballard, T.E.3
Basso, A.4
Cavanagh, J.5
Melander, C.6
-
33
-
-
68549120967
-
Amide isosteres of oroidin: Assessment of antibiofilm activity and C. elegans toxicity
-
Richards, J. J., Reyes, S., Stowe, S. D., Tucker, A. T., Ballard, T. E., Mathies, L. D., et al. (2009). Amide isosteres of oroidin: assessment of antibiofilm activity and C. elegans toxicity. J Med Chem 52:4582-4585.
-
(2009)
J Med Chem
, vol.52
, pp. 4582-4585
-
-
Richards, J.J.1
Reyes, S.2
Stowe, S.D.3
Tucker, A.T.4
Ballard, T.E.5
Mathies, L.D.6
-
34
-
-
0004282618
-
-
Cold Spring Harbor, New York, USA: Cold Spring Harbor Laboratory Press
-
Riddle, D. L., Blumenthal, T., Meyer, B. J., Priess, J. R. (Eds.). (1997). C. elegans II. Cold Spring Harbor, New York, USA: Cold Spring Harbor Laboratory Press.
-
(1997)
C. Elegans II
-
-
Riddle, D.L.1
Blumenthal, T.2
Meyer, B.J.3
Priess, J.R.4
-
35
-
-
77951226720
-
Synergistic effects between conventional antibiotics and 2-aminoimidazole-derived antibiofilm agents
-
Rogers, S. A., Huigens, R. W., III, Cavanagh, J., Melander, C. (2010). Synergistic effects between conventional antibiotics and 2-aminoimidazole- derived antibiofilm agents. Antimicrob Agents Chemother 54:2112-2118.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 2112-2118
-
-
Rogers, S.A.1
Huigens III, R.W.2
Cavanagh, J.3
Melander, C.4
-
36
-
-
47749145801
-
Construction and screening of a 2-aminoimidazole library identifies a small molecule capable of inhibiting and dispersing bacterial biofilms across order, class, and phylum
-
Rogers, S. A., Melander, C. (2008). Construction and screening of a 2-aminoimidazole library identifies a small molecule capable of inhibiting and dispersing bacterial biofilms across order, class, and phylum. Angew Chem Int Ed 47:5229-5231.
-
(2008)
Angew Chem Int Ed
, vol.47
, pp. 5229-5231
-
-
Rogers, S.A.1
Melander, C.2
-
37
-
-
0036407233
-
Biofilms as complex differentiated communities
-
DOI 10.1146/annurev.micro.56.012302.160705
-
Stoodley, P., Sauer, K., Davies, D. G., Costerton, J. W. (2002). Biofilms as complex differentiated communities. Annu Rev Microbiol 56:187-209. (Pubitemid 35217453)
-
(2002)
Annual Review of Microbiology
, vol.56
, pp. 187-209
-
-
Stoodley, P.1
Sauer, K.2
Davies, D.G.3
Costerton, J.W.4
-
38
-
-
0035166895
-
Quantitative assessment of primary skin irritants in vitro in a cytotoxicity model: Comparison with in vivo human irritation tests
-
DOI 10.1046/j.1365-2133.2001.04497.x
-
Wilhelm, K. P., Böttjer, B., Siegers, C. P. (2001). Quantitative assessment of primary skin irritants in vitro in a cytotoxicity model: comparison with in vivo human irritation tests. Br J Dermatol 145:709-715. (Pubitemid 33078340)
-
(2001)
British Journal of Dermatology
, vol.145
, Issue.5
, pp. 709-715
-
-
Wilhelm, K.-P.1
Bottjer, B.2
Siegers, C.-P.3
-
39
-
-
0028318171
-
Quantitative in vitro assessment of N-alkyl sulphate-induced cytotoxicity in human keratinocytes (HaCaT). Comparison with in vivo human irritation tests
-
Wilhelm, K. P., Samblebe, M., Siegers, C. P. (1994). Quantitative in vitro assessment of N-alkyl sulphate-induced cytotoxicity in human keratinocytes (HaCaT). Comparison with in vivo human irritation tests. Br J Dermatol 130:18-23.
-
(1994)
Br J Dermatol
, vol.130
, pp. 18-23
-
-
Wilhelm, K.P.1
Samblebe, M.2
Siegers, C.P.3
-
40
-
-
0004291817
-
-
Cold Spring Harbor, New York, USA: Cold Spring Harbor Laboratory Press
-
Wood, W. B. (Ed.). (1988). The nematode Caenorhabditis elegans. Cold Spring Harbor, New York, USA: Cold Spring Harbor Laboratory Press.
-
(1988)
The Nematode Caenorhabditis Elegans
-
-
Wood, W.B.1
|