Constitutive plasmacytoid dendritic cell migration to the splenic white pulp is cooperatively regulated by CCR7- and CXCR4-mediated signaling

Journal of Immunology

Volumn 189, Issue 1, 2012, Pages 191-199

  Umemoto, Eiji ^a,b   Otani, Kazuhiro ^c   Ikeno, Takashi ^a,b   Garcia, Noel Verjan ^a   Hayasaka, Haruko ^a,b   Bai, Zhongbin ^b   Jang, Myoung Ho ^b   Tanaka, Toshiyuki ^d   Nagasawa, Takashi ^e   Ueda, Koichi ^c   Miyasaka, Masayuki ^a,b  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c OSAKA MEDICAL COLLEGE   (Japan)

^d HYOGO COLLEGE OF MEDICINE   (Japan)

^e KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR7; CHEMOKINE RECEPTOR CXCR4; INTERCELLULAR ADHESION MOLECULE 1; SECONDARY LYMPHOID TISSUE CHEMOKINE; STROMAL CELL DERIVED FACTOR 1;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CHEMOTAXIS; CONTROLLED STUDY; FLOW CYTOMETRY; IMMUNOHISTOLOGY; IN VITRO STUDY; MOUSE; NONHUMAN; PLASMACYTOID DENDRITIC CELL; PRIORITY JOURNAL; PROTEIN BINDING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPLEEN; SPLEEN CELL; SPLENIC WHITE PULP; STEADY STATE; WILD TYPE;

ANIMALS; CELL MOVEMENT; DENDRITIC CELLS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; RECEPTORS, CCR7; RECEPTORS, CXCR4; SIGNAL TRANSDUCTION; SPLEEN;

EID: 84862880283     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1200802     Document Type: Article

References (45)

1. Liu, Y. J. 2005. IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors. Annu. Rev. Immunol. 23: 275-306.
2. Barchet, W., M. Cella, and M. Colonna. 2005. Plasmacytoid dendritic cells - virus experts of innate immunity. Semin. Immunol. 17: 253-261. (Pubitemid 40981931)
3. Colonna, M., G. Trinchieri, and Y. J. Liu. 2004. Plasmacytoid dendritic cells in immunity. Nat. Immunol. 5: 1219-1226. (Pubitemid 41057736)
4. Sozzani, S., W. Vermi, A. Del Prete, and F. Facchetti. 2010. Trafficking properties of plasmacytoid dendritic cells in health and disease. Trends Immunol. 31: 270-277.
5. Hadeiba, H., T. Sato, A. Habtezion, C. Oderup, J. Pan, and E. C. Butcher. 2008. CCR9 expression defines tolerogenic plasmacytoid dendritic cells able to suppress acute graft-versus-host disease. Nat. Immunol. 9: 1253-1260.
6. Goubier, A., B. Dubois, H. Gheit, G. Joubert, F. Villard-Truc, C. Asselin-Paturel, G. Trinchieri, and D. Kaiserlian. 2008. Plasmacytoid dendritic cells mediate oral tolerance. Immunity 29: 464-475.
7. + dendritic cells endowed with type 1 interferon production capacity and tolerogenic potential. Blood 100: 383-390.
8. Ochando, J. C., C. Homma, Y. Yang, A. Hidalgo, A. Garin, F. Tacke, V. Angeli, Y. Li, P. Boros, Y. Ding, et al. 2006. Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts. Nat. Immunol. 7: 652-662. (Pubitemid 43797347)
9. Takagi, H., T. Fukaya, K. Eizumi, Y. Sato, K. Sato, A. Shibazaki, H. Otsuka, A. Hijikata, T. Watanabe, O. Ohara, et al. 2011. Plasmacytoid dendritic cells are crucial for the initiation of inflammation and T cell immunity in vivo. Immunity 35: 958-971.
10. + cells in mouse lymph nodes and spleen display characteristics of plasmacytoid dendritic cells. J. Exp. Med. 194: 1171-1178.
11. Blasius, A. L., M. Cella, J. Maldonado, T. Takai, and M. Colonna. 2006. Siglec-H is an IPC-specific receptor that modulates type I IFN secretion through DAP12. Blood 107: 2474-2476. (Pubitemid 43345570)
12. Blasius, A. L., E. Giurisato, M. Cella, R. D. Schreiber, A. S. Shaw, and M. Colonna. 2006. Bone marrow stromal cell antigen 2 is a specific marker of type I IFN-producing cells in the naive mouse, but a promiscuous cell surface antigen following IFN stimulation. J. Immunol. 177: 3260-3265. (Pubitemid 44277845)
13. Cella, M., D. Jarrossay, F. Facchetti, O. Alebardi, H. Nakajima, A. Lanzavecchia, and M. Colonna. 1999. Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon. Nat. Med. 5: 919-923. (Pubitemid 29372419)
14. Yoneyama, H., K. Matsuno, Y. Zhang, T. Nishiwaki, M. Kitabatake, S. Ueha, S. Narumi, S. Morikawa, T. Ezaki, B. Lu, et al. 2004. Evidence for recruitment of plasmacytoid dendritic cell precursors to inflamed lymph nodes through high endothelial venules. Int. Immunol. 16: 915-928. (Pubitemid 38967174)
15. Diacovo, T. G., A. L. Blasius, T. W. Mak, M. Cella, and M. Colonna. 2005. Adhesive mechanisms governing interferon-producing cell recruitment into lymph nodes. J. Exp. Med. 202: 687-696. (Pubitemid 41248419)
16. Seth, S., L. Oberdörfer, R. Hyde, K. Hoff, V. Thies, T. Worbs, S. Schmitz, and R. Förster. 2011. CCR7 essentially contributes to the homing of plasmacytoid dendritic cells to lymph nodes under steady-state as well as inflammatory conditions. J. Immunol. 186: 3364-3372.
17. Brawand, P., D. R. Fitzpatrick, B. W. Greenfield, K. Brasel, C. R. Maliszewski, and T. De Smedt. 2002. Murine plasmacytoid pre-dendritic cells generated from Flt3 ligand-supplemented bone marrow cultures are immature APCs. J. Immunol. 169: 6711-6719. (Pubitemid 36899255)
18. Krug, A., R. Uppaluri, F. Facchetti, B. G. Dorner, K. C. Sheehan, R. D. Schreiber, M. Cella, and M. Colonna. 2002. IFN-producing cells respond to CXCR3 ligands in the presence of CXCL12 and secrete inflammatory chemokines upon activation. J. Immunol. 169: 6079-6083. (Pubitemid 36903450)
19. Asselin-Paturel, C., G. Brizard, K. Chemin, A. Boonstra, A. O'Garra, A. Vicari, and G. Trinchieri. 2005. Type I interferon dependence of plasmacytoid dendritic cell activation and migration. J. Exp. Med. 201: 1157-1167. (Pubitemid 40528442)
20. Penna, G., S. Sozzani, and L. Adorini. 2001. Cutting edge: selective usage of chemokine receptors by plasmacytoid dendritic cells. J. Immunol. 167: 1862-1866. (Pubitemid 32747488)
21. Vanbervliet, B., N. Bendriss-Vermare, C. Massacrier, B. Homey, O. de Bouteiller, F. Brière, G. Trinchieri, and C. Caux. 2003. The inducible CXCR3 ligands control plasmacytoid dendritic cell responsiveness to the constitutive chemokine stromal cell-derived factor 1 (SDF-1)/CXCL12. J. Exp. Med. 198: 823-830. (Pubitemid 37087780)
22. Kohara, H., Y. Omatsu, T. Sugiyama, M. Noda, N. Fujii, and T. Nagasawa. 2007. Development of plasmacytoid dendritic cells in bone marrow stromal cell niches requires CXCL12-CXCR4 chemokine signaling. Blood 110: 4153-4160. (Pubitemid 351377776)
23. Tassone, L., D. Moratto, W. Vermi, M. De Francesco, L. D. Notarangelo, F. Porta, V. Lougaris, F. Facchetti, A. Plebani, and R. Badolato. 2010. Defect of plasmacytoid dendritic cells in warts, hypogammaglobulinemia, infections, myelokathexis (WHIM) syndrome patients. Blood 116: 4870-4873.
24. Asselin-Paturel, C., G. Brizard, J. J. Pin, F. Brière, and G. Trinchieri. 2003. Mouse strain differences in plasmacytoid dendritic cell frequency and function revealed by a novel monoclonal antibody. J. Immunol. 171: 6466-6477. (Pubitemid 37532075)
25. Nakano, H., S. Mori, H. Yonekawa, H. Nariuchi, A. Matsuzawa, and T. Kakiuchi. 1998. A novel mutant gene involved in T-lymphocyte-specific homing into peripheral lymphoid organs on mouse chromosome 4. Blood 91: 2886-2895. (Pubitemid 28227539)
26. Förster, R., A. Schubel, D. Breitfeld, E. Kremmer, I. Renner-Müller, E. Wolf, and M. Lipp. 1999. CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs. Cell 99: 23-33. (Pubitemid 29468627)
27. Ara, T., K. Tokoyoda, T. Sugiyama, T. Egawa, K. Kawabata, and T. Nagasawa. 2003. Long-term hematopoietic stem cells require stromal cell-derived factor-1 for colonizing bone marrow during ontogeny. Immunity 19: 257-267.
28. Umemoto, E., T. Tanaka, H. Kanda, S. Jin, K. Tohya, K. Otani, T. Matsutani, M. Matsumoto, Y. Ebisuno, M. H. Jang, et al. 2006. Nepmucin, a novel HEV sialomucin, mediates L-selectin-dependent lymphocyte rolling and promotes lymphocyte adhesion under flow. J. Exp. Med. 203: 1603-1614. (Pubitemid 43877619)
29. Manjunath, N., P. Shankar, J. Wan, W. Weninger, M. A. Crowley, K. Hieshima, T. A. Springer, X. Fan, H. Shen, J. Lieberman, and U. H. von Andrian. 2001. Effector differentiation is not prerequisite for generation of memory cytotoxic T lymphocytes. J. Clin. Invest. 108: 871-878. (Pubitemid 32880296)
30. Matsutani, T., T. Tanaka, K. Tohya, K. Otani, M. H. Jang, E. Umemoto, K. Taniguchi, H. Hayasaka, K. Ueda, and M. Miyasaka. 2007. Plasmacytoid dendritic cells employ multiple cell adhesion molecules sequentially to interact with high endothelial venule cells - molecular basis of their trafficking to lymph nodes. Int. Immunol. 19: 1031-1037. (Pubitemid 47434236)
31. Jang, M. H., N. Sougawa, T. Tanaka, T. Hirata, T. Hiroi, K. Tohya, Z. Guo, E. Umemoto, Y. Ebisuno, B. G. Yang, et al. 2006. CCR7 is critically important for migration of dendritic cells in intestinal lamina propria to mesenteric lymph nodes. J. Immunol. 176: 803-810. (Pubitemid 43099676)
32. Gilliet, M., A. Boonstra, C. Paturel, S. Antonenko, X. L. Xu, G. Trinchieri, A. O'Garra, and Y. J. Liu. 2002. The development of murine plasmacytoid dendritic cell precursors is differentially regulated by FLT3-ligand and granulocyte/macrophage colony-stimulating factor. J. Exp. Med. 195: 953-958. (Pubitemid 34286765)
33. Yang, B. G., T. Tanaka, M. H. Jang, Z. Bai, H. Hayasaka, and M. Miyasaka. 2007. Binding of lymphoid chemokines to collagen IV that accumulates in the basal lamina of high endothelial venules: its implications in lymphocyte trafficking. J. Immunol. 179: 4376-4382.
34. Datema, R., L. Rabin, M. Hincenbergs, M. B. Moreno, S. Warren, V. Linquist, B. Rosenwirth, J. Seifert, and J. M. McCune. 1996. Antiviral efficacy in vivo of the anti-human immunodeficiency virus bicyclam SDZ SID 791 (JM 3100), an inhibitor of infectious cell entry. Antimicrob. Agents Chemother. 40: 750-754. (Pubitemid 26075438)
35. Matthys, P., S. Hatse, K. Vermeire, A. Wuyts, G. Bridger, G. W. Henson, E. De Clercq, A. Billiau, and D. Schols. 2001. AMD3100, a potent and specific antagonist of the stromal cell-derived factor-1 chemokine receptor CXCR4, inhibits autoimmune joint inflammation in IFN-g receptor-deficient mice. J. Immunol. 167: 4686-4692. (Pubitemid 32954350)
36. Nakano, H., K. L. Lin, M. Yanagita, C. Charbonneau, D. N. Cook, T. Kakiuchi, and M. D. Gunn. 2009. Blood-derived inflammatory dendritic cells in lymph nodes stimulate acute T helper type 1 immune responses. Nat. Immunol. 10: 394-402.
37. Segura, E., J. Wong, and J. A. Villadangos. 2009. Cutting edge: B220+CCR9-dendritic cells are not plasmacytoid dendritic cells but are precursors of conventional dendritic cells. J. Immunol. 183: 1514-1517.
38. Bai, Z., H. Hayasaka, M. Kobayashi, W. Li, Z. Guo, M. H. Jang, A. Kondo, B. I. Choi, Y. Iwakura, and M. Miyasaka. 2009. CXC chemokine ligand 12 promotes CCR7-dependent naive T cell trafficking to lymph nodes and Peyer's patches. J. Immunol. 182: 1287-1295.
39. Bajénoff, M., N. Glaichenhaus, and R. N. Germain. 2008. Fibroblastic reticular cells guide T lymphocyte entry into and migration within the splenic T cell zone. J. Immunol. 181: 3947-3954.
40. Matsuno, K., H. Ueta, Z. Shu, X. Xue-Dong, Y. Sawanobori, Y. Kitazawa, Y. Bin, M. Yamashita, and C. Shi. 2010. The microstructure of secondary lymphoid organs that support immune cell trafficking. Arch. Histol. Cytol. 73: 1-21.
41. Ato, M., H. Nakano, T. Kakiuchi, and P. M. Kaye. 2004. Localization of marginal zone macrophages is regulated by C-C chemokine ligands 21/19. J. Immunol. 173: 4815-4820. (Pubitemid 39387761)
42. Nolte, M. A., J. A. Beliën, I. Schadee-Eestermans, W. Jansen, W. W. Unger, N. van Rooijen, G. Kraal, and R. E. Mebius. 2003. A conduit system distributes chemokines and small blood-borne molecules through the splenic white pulp. J. Exp. Med. 198: 505-512.
43. Worbs, T., T. R. Mempel, J. Bölter, U. H. von Andrian, and R. Förster. 2007. CCR7 ligands stimulate the intranodal motility of T lymphocytes in vivo. J. Exp. Med. 204: 489-495. (Pubitemid 46457073)
44. Paoletti, S., V. Petkovic, S. Sebastiani, M. G. Danelon, M. Uguccioni, and B. O. Gerber. 2005. A rich chemokine environment strongly enhances leukocyte migration and activities. Blood 105: 3405-3412. (Pubitemid 40628179)
45. Hoogewerf, A. J., G. S. Kuschert, A. E. Proudfoot, F. Borlat, I. Clark-Lewis, C. A. Power, and T. N. Wells. 1997. Glycosaminoglycans mediate cell surface oligomerization of chemokines. Biochemistry 36: 13570-13578. (Pubitemid 27481603)