Polymeric micelles based on poly(ethylene glycol) block poly(racemic amino acids) hybrid polypeptides: Conformation-facilitated drug-loading behavior and potential application as effective anticancer drug carriers

International Journal of Nanomedicine

Volumn 7, Issue , 2012, Pages 109-122

  Gu, Peng Fei ^a   Xu, Hui ^a   Sui, Bo Wen ^b   Gou, Jing Xin ^a   Meng, Ling Kuo ^a   Sun, Feng ^a   Wang, Xiu Jun ^a   Qi, NA ^a   Zhang, YU ^a   He, Hai Bing ^a   Tang, Xing ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b JILIN UNIVERSITY   (China)

Author keywords

Anticancer nanomedicine; Conformation; High drug loading ability; Micelles; Racemic polypeptides

Indexed keywords

AMINO ACID; ANTINEOPLASTIC AGENT; COPOLYMER; DOCETAXEL; DRUG CARRIER; LEUCINE; MACROGOL; POLYPEPTIDE; POLY(ETHYLENE GLYCOL) B POLY(RACEMIC LEUCINE); UNCLASSIFIED DRUG;

ARTICLE; BIOCOMPATIBILITY; BREAST CANCER; CANCER CELL; DIALYSIS; DRUG EFFICACY; ENDOTHELIUM CELL; FACILITATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROPHOBICITY; IN VITRO STUDY; MICELLE; PARTICLE SIZE; PROTEIN CONFORMATION; UMBILICAL VEIN; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOTOXICITY TEST; DRUG CONFORMATION; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; SUSTAINED DRUG RELEASE; TIMED DRUG RELEASE; UMBILICAL VEIN ENDOTHELIAL CELL;

EID: 84863012548     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/ijn.s27475     Document Type: Article

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