Development of a validated high-throughput LC-ESI-MS method for determination of sirolimus on dried blood spots

Biomedical Chromatography

Volumn 24, Issue 12, 2010, Pages 1356-1364

  Rao, R Nageswara ^a   Maurya, Pawan K ^a   Ramesh, M ^a   Srinivas, R ^a   Agwane, Sachin B ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

Dried blood spots; High throughput; LC ESI MS; Monolithic column; Sirolimus

Indexed keywords

BLOOD; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; SILICA; SOLVENT EXTRACTION; THROUGHPUT;

BIMODAL PORE STRUCTURE; DRIED BLOOD SPOT; HIGH-THROUGHPUT; LIQUID CHROMATOGRAPHY ELECTROSPRAY; LIQUID CHROMATOGRAPHY-ELECTROSPRAY IONIZATION MASS SPECTROMETRIC; MONOLITHIC COLUMNS; REVERSED PHASE; SILICA ROD; SIROLIMUS; SPECTROMETRIC METHODS;

ELECTROSPRAY IONIZATION;

RAPAMYCIN;

ACCURACY; ANALYTIC METHOD; ANIMAL EXPERIMENT; ARTICLE; BLOOD ANALYSIS; CONTROLLED STUDY; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; FLOW RATE; HIGH THROUGHPUT SCREENING; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; RAT; REVERSED PHASE LIQUID CHROMATOGRAPHY; SOLVENT EXTRACTION; VALIDATION STUDY;

EID: 78449263943     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1450     Document Type: Article

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