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Volumn 151, Issue 3, 2005, Pages 693-706

Metabolic flux analysis of Escherichia coli in glucose-limited continuous culture. I. Growth-rate-dependent metabolic efficiency at steady state

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; AMMONIA; CARBON; CARBON DIOXIDE; GLUCOSE; OXYGEN; PENTOSE PHOSPHATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SUGAR; TRICARBOXYLIC ACID;

EID: 15844371174     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/mic.0.27481-0     Document Type: Article
Times cited : (152)

References (42)
  • 1
    • 0019132335 scopus 로고
    • Are growth rates of Escherichia coli in batch cultures limited by respiration?
    • Andersen, K. B. & von Meyenburg, K. (1980). Are growth rates of Escherichia coli in batch cultures limited by respiration? J Bacteriol 144, 114-123.
    • (1980) J. Bacteriol. , vol.144 , pp. 114-123
    • Andersen, K.B.1    von Meyenburg, K.2
  • 2
    • 0014353859 scopus 로고
    • The energy charge of the adenylate pool as a regulatory parameter. Interaction with feedback modifiers
    • Atkinson, D. E. (1968). The energy charge of the adenylate pool as a regulatory parameter. Interaction with feedback modifiers. Biochemistry 7, 4030-4034.
    • (1968) Biochemistry , vol.7 , pp. 4030-4034
    • Atkinson, D.E.1
  • 3
    • 0000404096 scopus 로고
    • The growth of micro-organisms in relation to their energy supply
    • Bauchop, T. & Elsden, S. R. (1960). The growth of micro-organisms in relation to their energy supply. J Gen Microbiol 23, 457-469.
    • (1960) J. Gen. Microbiol. , vol.23 , pp. 457-469
    • Bauchop, T.1    Elsden, S.R.2
  • 4
    • 0002546375 scopus 로고
    • A simple and reliable method for the determination of cellular RNA content
    • Benthin, S., Nielsen, J. & Villadsen, J. (1991). A simple and reliable method for the determination of cellular RNA content. Biotechnol Tech 5, 39-42.
    • (1991) Biotechnol. Tech. , vol.5 , pp. 39-42
    • Benthin, S.1    Nielsen, J.2    Villadsen, J.3
  • 5
    • 0032945184 scopus 로고    scopus 로고
    • The udhA gene of Escherichia coli encodes a soluble pyridine nucleotide transhydrogenase
    • Boonstra, B., French, C. E., Wainwright, I. & Bruce, N. C. (1999). The udhA gene of Escherichia coli encodes a soluble pyridine nucleotide transhydrogenase. J Bacteriol 181 1030-1034.
    • (1999) J. Bacteriol. , vol.181 , pp. 1030-1034
    • Boonstra, B.1    French, C.E.2    Wainwright, I.3    Bruce, N.C.4
  • 6
    • 0015499043 scopus 로고
    • Function of energy-dependent transhydrogenase in Escherichia coli
    • Bragg, P. D., Davies, P. L. & Hou, C. (1972). Function of energy-dependent transhydrogenase in Escherichia coli. Biochem Biophys Res Commun 47, 1248-1255.
    • (1972) Biochem. Biophys. Res. Commun. , vol.47 , pp. 1248-1255
    • Bragg, P.D.1    Davies, P.L.2    Hou, C.3
  • 7
    • 0035856579 scopus 로고    scopus 로고
    • Metabolic flux response to phosphoglucose isomerase knock-out in Escherichia coli and impact of overexpression of the soluble transhydrogenase UdhA
    • Canonaco, F., Hess, T. A., Heri, S., Wang, T., Szyperski, T. & Sauer, U. (2001). Metabolic flux response to phosphoglucose isomerase knock-out in Escherichia coli and impact of overexpression of the soluble transhydrogenase UdhA. FEMS Microbiol Lett 204, 247-252.
    • (2001) FEMS Microbiol. Lett. , vol.204 , pp. 247-252
    • Canonaco, F.1    Hess, T.A.2    Heri, S.3    Wang, T.4    Szyperski, T.5    Sauer, U.6
  • 8
    • 0033107836 scopus 로고    scopus 로고
    • Classification and sensitivity analysis of a proposed primary metabolic reaction network for Streptomyces lividans
    • Daae, E. B. & Ison, A. P. (1999). Classification and sensitivity analysis of a proposed primary metabolic reaction network for Streptomyces lividans. Metab Eng 1, 153-165.
    • (1999) Metab. Eng. , vol.1 , pp. 153-165
    • Daae, E.B.1    Ison, A.P.2
  • 9
    • 0003127926 scopus 로고
    • Regulation of glucose metabolism in bacterial systems
    • Doelle, H. W., Ewing, K. N. & Hollywood, N. W. (1982). Regulation of glucose metabolism in bacterial systems. Adv Biochem Eng 23, 1-35.
    • (1982) Adv. Biochem. Eng. , vol.23 , pp. 1-35
    • Doelle, H.W.1    Ewing, K.N.2    Hollywood, N.W.3
  • 10
    • 0017073612 scopus 로고
    • The energetics of Escherichia coli during aerobic growth in continuous culture
    • Farmer, I. S. & Jones, C. W. (1976). The energetics of Escherichia coli during aerobic growth in continuous culture. Eur J Biochem 67, 115-122.
    • (1976) Eur. J. Biochem. , vol.67 , pp. 115-122
    • Farmer, I.S.1    Jones, C.W.2
  • 12
    • 0026832754 scopus 로고
    • Acetic acid formation in Escherichia coli fermentation
    • Han, K., Lim, H. C. & Hong, J. (1992). Acetic acid formation in Escherichia coli fermentation. Biotechnol Bioeng 39, 663-671.
    • (1992) Biotechnol. Bioeng. , vol.39 , pp. 663-671
    • Han, K.1    Lim, H.C.2    Hong, J.3
  • 14
    • 0035829831 scopus 로고    scopus 로고
    • On-line estimation of the metabolic burden resulting from synthesis of plasmid-encoded and heat-shock proteins by monitoring respiratory energy generation
    • Hoffmann, F. & Rinas, U. (2001). On-line estimation of the metabolic burden resulting from synthesis of plasmid-encoded and heat-shock proteins by monitoring respiratory energy generation. Biotechnol Bioeng 76, 333-340.
    • (2001) Biotechnol. Bioeng. , vol.76 , pp. 333-340
    • Hoffmann, F.1    Rinas, U.2
  • 15
    • 0345529074 scopus 로고    scopus 로고
    • Responses of the central metabolism in Escherichia coli to phosphoglucose isomerase and glucose-6-phosphate dehydrogenase knockouts
    • Hua, Q., Yang, C., Baba, T., Mori, H. & Shimizu, K. (2003). Responses of the central metabolism in Escherichia coli to phosphoglucose isomerase and glucose-6-phosphate dehydrogenase knockouts. J Bacteriol 185, 7053-7067.
    • (2003) J. Bacteriol. , vol.185 , pp. 7053-7067
    • Hua, Q.1    Yang, C.2    Baba, T.3    Mori, H.4    Shimizu, K.5
  • 16
    • 0004212736 scopus 로고
    • Chemical synthesis of the bacterial cell: Polymerization, biosynthesis, fueling reactions, and transport
    • Sunderland, MA: Sinauer Associates
    • Ingraham, J. L., Maaloe, O. & Neidhardt, F. C. (1983). Chemical synthesis of the bacterial cell: polymerization, biosynthesis, fueling reactions, and transport. In Growth of the Bacterial Cell, pp. 87-173. Sunderland, MA: Sinauer Associates.
    • (1983) Growth of the Bacterial Cell , pp. 87-173
    • Ingraham, J.L.1    Maaloe, O.2    Neidhardt, F.C.3
  • 18
    • 0029239706 scopus 로고
    • Simple fed-batch technique for high cell density cultivation of Escherichia coli
    • Korz, D. J., Rinas, U., Hellmuth, K., Sanders, E. A. & Deckwer, W.-D. (1995). Simple fed-batch technique for high cell density cultivation of Escherichia coli. J Biotechnol 39, 59-65.
    • (1995) J. Biotechnol. , vol.39 , pp. 59-65
    • Korz, D.J.1    Rinas, U.2    Hellmuth, K.3    Sanders, E.A.4    Deckwer, W.-D.5
  • 19
    • 0025405421 scopus 로고
    • Simple constrained-optimization view of acetate overflow in E. coli
    • Majewski, R. A. & Domach, M. M. (1990). Simple constrained-optimization view of acetate overflow in E. coli. Biotechnol Bioeng 35, 732-738.
    • (1990) Biotechnol. Bioeng. , vol.35 , pp. 732-738
    • Majewski, R.A.1    Domach, M.M.2
  • 22
    • 1842582933 scopus 로고    scopus 로고
    • Transcription levels of key metabolic genes are the cause for different glucose utilization pathways in E. coli B (BL21) and E. coli K (JM109)
    • Phue, J.-N. & Shiloach, J. (2004). Transcription levels of key metabolic genes are the cause for different glucose utilization pathways in E. coli B (BL21) and E. coli K (JM109). J Biotechnol 109, 21-30.
    • (2004) J. Biotechnol. , vol.109 , pp. 21-30
    • Phue, J.-N.1    Shiloach, J.2
  • 23
    • 43049089438 scopus 로고
    • The maintenance energy of bacteria in growing cultures
    • Pirt, J. (1965). The maintenance energy of bacteria in growing cultures. Proc R Soc Lond B Biol Sci 163, 224-231.
    • (1965) Proc. R. Soc. Lond. B Biol. Sci. , vol.163 , pp. 224-231
    • Pirt, J.1
  • 24
    • 0343035686 scopus 로고    scopus 로고
    • Stoichiometric model of Escherichia coli metabolism: Incorporation of growth-rate dependent biomass composition and mechanistic energy requirements
    • Pramanik, J. & Keasling, J. D. (1997). Stoichiometric model of Escherichia coli metabolism: incorporation of growth-rate dependent biomass composition and mechanistic energy requirements. Biotechnol Bioeng 56, 398-421.
    • (1997) Biotechnol. Bioeng. , vol.56 , pp. 398-421
    • Pramanik, J.1    Keasling, J.D.2
  • 25
    • 0021831859 scopus 로고
    • Mass culture of Escherichia coli: Medium development for low and high density cultivation of Escherichia coli B/r in minimal and complex media
    • Reiling, H. E., Laurila, H. & Fiechter, A. (1985). Mass culture of Escherichia coli: medium development for low and high density cultivation of Escherichia coli B/r in minimal and complex media. J Biotechnol 2, 191-206.
    • (1985) J. Biotechnol. , vol.2 , pp. 191-206
    • Reiling, H.E.1    Laurila, H.2    Fiechter, A.3
  • 27
    • 0017643367 scopus 로고
    • Energy-linked nicotinamide nucleotide transhydrogenases
    • Rydström, J. (1977). Energy-linked nicotinamide nucleotide transhydrogenases. Biochim Biophys Acta 463, 155-184.
    • (1977) Biochim. Biophys. Acta , vol.463 , pp. 155-184
    • Rydström, J.1
  • 28
    • 0025868196 scopus 로고
    • Improved ion-pair high-performance liquid chromatographic method for the quantification of a wide variety of nucleotides and sugar-nucleotides in animal cells
    • Ryll, T. & Wagner, R. (1991). Improved ion-pair high-performance liquid chromatographic method for the quantification of a wide variety of nucleotides and sugar-nucleotides in animal cells. J Chromatogr 570, 77-88.
    • (1991) J. Chromatogr. , vol.570 , pp. 77-88
    • Ryll, T.1    Wagner, R.2
  • 30
    • 0032838693 scopus 로고    scopus 로고
    • Quantitative analysis of metabolic fluxes in Escherichia coli, using two-dimensional NMR spectroscopy and complete isotopomer models
    • Schmidt, K., Nielsen, J. & Villadsen, J. (1999). Quantitative analysis of metabolic fluxes in Escherichia coli, using two-dimensional NMR spectroscopy and complete isotopomer models. J Biotechnol 71, 175-189.
    • (1999) J. Biotechnol. , vol.71 , pp. 175-189
    • Schmidt, K.1    Nielsen, J.2    Villadsen, J.3
  • 31
    • 0029804432 scopus 로고    scopus 로고
    • Growth rate control of protein and nucleic acid content in Streptomyces coelicolor A3(2) and Escherichia coli B/r
    • Shahab, N., Flett, F., Oliver, S. G. & Butler, P. R. (1996). Growth rate control of protein and nucleic acid content in Streptomyces coelicolor A3(2) and Escherichia coli B/r. Microbiology 142, 1927-1935.
    • (1996) Microbiology , vol.142 , pp. 1927-1935
    • Shahab, N.1    Flett, F.2    Oliver, S.G.3    Butler, P.R.4
  • 32
    • 0015910716 scopus 로고
    • A theoretical study on the amount of ATP required for synthesis of microbial cell material
    • Stouthamer, A. H. (1973). A theoretical study on the amount of ATP required for synthesis of microbial cell material. Antonie van Leeuwenhoek 39, 545-565.
    • (1973) Antonie Van Leeuwenhoek , vol.39 , pp. 545-565
    • Stouthamer, A.H.1
  • 33
    • 0015921314 scopus 로고
    • Utilization of energy for growth and maintenance in continuous and batch cultures of microorganisms. A reevaluation of the method for the determination of ATP production by measuring molar growth yields
    • Stouthamer, A. H. & Bettenhaussen, C. (1973). Utilization of energy for growth and maintenance in continuous and batch cultures of microorganisms. A reevaluation of the method for the determination of ATP production by measuring molar growth yields. Biochim Biophys Acta 301, 53-70.
    • (1973) Biochim. Biophys. Acta , vol.301 , pp. 53-70
    • Stouthamer, A.H.1    Bettenhaussen, C.2
  • 34
    • 0343471961 scopus 로고    scopus 로고
    • In vivo analysis of metabolic dynamics in Saccharomyces cerevisiae. I. Experimental observations
    • Theobald, U., Mailinger, W., Baltes, M., Rizzi, M. & Reuss, M. (1997). In vivo analysis of metabolic dynamics in Saccharomyces cerevisiae. I. Experimental observations. Biotechnol Bioeng 55, 305-316.
    • (1997) Biotechnol. Bioeng. , vol.55 , pp. 305-316
    • Theobald, U.1    Mailinger, W.2    Baltes, M.3    Rizzi, M.4    Reuss, M.5
  • 35
    • 0001985853 scopus 로고
    • Flux determination in cellular bioreaction networks: Applications to lysine fermentations
    • Edited by S. K. Sikdar, M. Bier & P. Todd. Boca Raton, FL: CRC Press
    • Vallino, J. J. & Stephanopoulos, G. (1990). Flux determination in cellular bioreaction networks: applications to lysine fermentations. In Frontiers in Bioprocessing, pp. 205-219. Edited by S. K. Sikdar, M. Bier & P. Todd. Boca Raton, FL: CRC Press.
    • (1990) Frontiers in Bioprocessing , pp. 205-219
    • Vallino, J.J.1    Stephanopoulos, G.2
  • 36
    • 0028973161 scopus 로고
    • A metabolic network stoichiometry analysis of microbial growth and product formation
    • van Gulik W. M. & Heijnen, J. J. (1995). A metabolic network stoichiometry analysis of microbial growth and product formation. Biotechnol Bioeng 48, 681-698.
    • (1995) Biotechnol. Bioeng. , vol.48 , pp. 681-698
    • van Gulik, W.M.1    Heijnen, J.J.2
  • 37
    • 0027723421 scopus 로고
    • Metabolic capabilities of Escherichia coli. II. Optimal growth patterns
    • Varma, A. & Palsson, B. O. (1993). Metabolic capabilities of Escherichia coli. II. Optimal growth patterns. J Theor Biol 165, 503-522.
    • (1993) J. Theor. Biol. , vol.165 , pp. 503-522
    • Varma, A.1    Palsson, B.O.2
  • 38
    • 0028146781 scopus 로고
    • Stoichiometric flux balance models quantitatively predict growth and metabolic by-product secretion in wild-type Escherichia coli W3110
    • Varma, A. & Palsson, B. O. (1994). Stoichiometric flux balance models quantitatively predict growth and metabolic by-product secretion in wild-type Escherichia coli W3110. Appl Environ Microbiol 60, 3724-3731.
    • (1994) Appl. Environ. Microbiol. , vol.60 , pp. 3724-3731
    • Varma, A.1    Palsson, B.O.2
  • 39
    • 0037027392 scopus 로고    scopus 로고
    • Metabolic adaptation of Escherichia coli during temperature-induced recombinant protein synthesis: 2. Redirection of metabolic fluxes
    • Weber, J., Hoffmann, F. & Rinas, U. (2002). Metabolic adaptation of Escherichia coli during temperature-induced recombinant protein synthesis: 2. Redirection of metabolic fluxes. Biotechnol Bioeng 80, 320-330.
    • (2002) Biotechnol. Bioeng. , vol.80 , pp. 320-330
    • Weber, J.1    Hoffmann, F.2    Rinas, U.3
  • 40
    • 15844406532 scopus 로고    scopus 로고
    • Metabolic flux analysis of Escherichia coli in glucose-limited continuous culture. II. Dynamic response to famine and feast, activation of the methylglyoxal pathway and oscillatory behaviour
    • Weber, J., Kayser, A. & Rinas, U. (2005). Metabolic flux analysis of Escherichia coli in glucose-limited continuous culture. II. Dynamic response to famine and feast, activation of the methylglyoxal pathway and oscillatory behaviour. Microbiology 151, 707-716.
    • (2005) Microbiology , vol.151 , pp. 707-716
    • Weber, J.1    Kayser, A.2    Rinas, U.3
  • 41
    • 0025514376 scopus 로고
    • A method to estimate the efficiency of oxidative phosphorylation and biomass yield from ATP of a facultative anaerobe in continuous culture
    • Zeng, A. P., Ross, A. & Deckwer, W.-D. (1990). A method to estimate the efficiency of oxidative phosphorylation and biomass yield from ATP of a facultative anaerobe in continuous culture. Biotechnol Bioeng 36, 965-969.
    • (1990) Biotechnol. Bioeng. , vol.36 , pp. 965-969
    • Zeng, A.P.1    Ross, A.2    Deckwer, W.-D.3


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