메뉴 건너뛰기




Volumn 2, Issue 2, 2011, Pages 75-80

Clinical use of amino acids as dietary supplement: Pros and cons

Author keywords

Amino acids; Definition of life; Muscle; Nutrition; Toxicogenomic

Indexed keywords

ALBUMIN; AMINO ACID; ARGININE; ESSENTIAL AMINO ACID; METHIONINE; NITROGEN; PROTEIN; UREA;

EID: 84862849207     PISSN: 21905991     EISSN: 21906009     Source Type: Journal    
DOI: 10.1007/s13539-011-0032-8     Document Type: Review
Times cited : (45)

References (53)
  • 1
    • 0004146634 scopus 로고
    • Cambridge: Cambridge University Press
    • Schrödinger E. What is life? Cambridge: Cambridge University Press; 1944.
    • (1944) What is Life?
    • Schrödinger, E.1
  • 2
    • 33750047895 scopus 로고    scopus 로고
    • Conditions for the emergence of life on the early Earth: summary and reflections
    • Jortner J. Conditions for the emergence of life on the early Earth: summary and reflections. Phil Trans Biol Sci. 2006; 361: 1877-91.
    • (2006) Phil Trans Biol Sci , vol.361 , pp. 1877-1891
    • Jortner, J.1
  • 3
    • 0014960411 scopus 로고
    • Shock synthesis of amino acids in simulated primitive environments
    • Bar-Nun A, Bar-Nun N, Bauer SH, Sagan C. Shock synthesis of amino acids in simulated primitive environments. Science. 1970; 168: 470-2.
    • (1970) Science , vol.168 , pp. 470-472
    • Bar-Nun, A.1    Bar-Nun, N.2    Bauer, S.H.3    Sagan, C.4
  • 4
    • 73849152920 scopus 로고
    • Studies of protein reserves. The relation between protein intake and resistance to protein deprivation
    • Halac Jr E. Studies of protein reserves. The relation between protein intake and resistance to protein deprivation. Am J Clin Nutr. 1962; 11: 574-6.
    • (1962) Am J Clin Nutr , vol.11 , pp. 574-576
    • Halac Jr., E.1
  • 5
    • 84951557815 scopus 로고
    • The utilization of energy-producing nutrients and protein as affected by the plane of protein intake
    • Forbes EB, Voris L, Bratzler JW, Wainio W. The utilization of energy-producing nutrients and protein as affected by the plane of protein intake. J Nutr. 1938; 15: 285.
    • (1938) J Nutr , vol.15 , pp. 285
    • Forbes, E.B.1    Voris, L.2    Bratzler, J.W.3    Wainio, W.4
  • 6
    • 37349084557 scopus 로고    scopus 로고
    • Amino acid metabolism and regulatory effects in aging
    • Timmerman K, Volpi E. Amino acid metabolism and regulatory effects in aging. Curr Opin Clin Nutr Metab Care. 2008; 11: 45-9.
    • (2008) Curr Opin Clin Nutr Metab Care , vol.11 , pp. 45-49
    • Timmerman, K.1    Volpi, E.2
  • 7
    • 64249113497 scopus 로고    scopus 로고
    • Dietary Guidelines should reflect new understandings about adult protein needs
    • doi:10.1186/1743-7075-6-12
    • Layman DK. Dietary Guidelines should reflect new understandings about adult protein needs. Nutr Metab. 2009; 6: 12. doi: 10. 1186/1743-7075-6-12.
    • (2009) Nutr Metab , vol.6 , pp. 12
    • Layman, D.K.1
  • 8
    • 0042068305 scopus 로고    scopus 로고
    • Essential amino acids are primarily responsible for the amino acid stimulation of muscle protein anabolism in healthy elderly adults
    • Volpi E, Kobayashi H, Sheffield-Moore M, Mittendorfer B, Wolfe RR. Essential amino acids are primarily responsible for the amino acid stimulation of muscle protein anabolism in healthy elderly adults. Am J Clin Nutr. 2003; 78: 250-8.
    • (2003) Am J Clin Nutr , vol.78 , pp. 250-258
    • Volpi, E.1    Kobayashi, H.2    Sheffield-Moore, M.3    Mittendorfer, B.4    Wolfe, R.R.5
  • 9
    • 79955612531 scopus 로고    scopus 로고
    • An overview of sarcopenia: facts and numbers on prevalence and clinical impact
    • von Haehling S, Morley JE, Anker SD. An overview of sarcopenia: facts and numbers on prevalence and clinical impact. J Cachexia Sarcopenia Muscle. 2010; 1: 129-33.
    • (2010) J Cachexia Sarcopenia Muscle , vol.1 , pp. 129-133
    • von Haehling, S.1    Morley, J.E.2    Anker, S.D.3
  • 10
    • 0344539190 scopus 로고
    • Plasma protein.V. The effect of the protein content of the diet on turnover
    • Steinbock HL, Tarver H. Plasma protein. V. The effect of the protein content of the diet on turnover. J Biol Chem. 1954; 209: 127-32.
    • (1954) J Biol Chem , vol.209 , pp. 127-132
    • Steinbock, H.L.1    Tarver, H.2
  • 13
    • 77957661352 scopus 로고    scopus 로고
    • Branched-chain amino acid supplementation promotes survival and supports cardiac and skeletal muscle mitochondrial biogenesis in middle-aged mice
    • D'Antona G, Ragni M, Cardile A, Tedesco L, Dossena M, Bruttini F, et al. Branched-chain amino acid supplementation promotes survival and supports cardiac and skeletal muscle mitochondrial biogenesis in middle-aged mice. Cell Metabol. 2010; 12: 362-72.
    • (2010) Cell Metabol , vol.12 , pp. 362-372
    • D'Antona, G.1    Ragni, M.2    Cardile, A.3    Tedesco, L.4    Dossena, M.5    Bruttini, F.6
  • 15
    • 14644444464 scopus 로고    scopus 로고
    • Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle
    • express article. 10.1096/fj.04-2640fje
    • Cuthbertson D, Smith K, Babraj J, Leese G, Waddell T, Atherton P, et al. Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle. FASEB J. 2005; 19: 422-4. express article. 10. 1096/fj. 04-2640fje.
    • (2005) FASEB J. , vol.19 , pp. 422-424
    • Cuthbertson, D.1    Smith, K.2    Babraj, J.3    Leese, G.4    Waddell, T.5    Atherton, P.6
  • 16
    • 75949099307 scopus 로고    scopus 로고
    • EAA supplementation to increase nitrogen intake improves muscle function during bed rest in the elderly
    • Ferrando AA, Paddon-Jones D, Hays NP, Kortebein P, Ronsen O, Williams RH, et al. EAA supplementation to increase nitrogen intake improves muscle function during bed rest in the elderly. Clin Nutr. 2010; 29: 18-23.
    • (2010) Clin Nutr , vol.29 , pp. 18-23
    • Ferrando, A.A.1    Paddon-Jones, D.2    Hays, N.P.3    Kortebein, P.4    Ronsen, O.5    Williams, R.H.6
  • 18
    • 0014290103 scopus 로고
    • Some problems in dietary amino acid requirements
    • Holt Jr LE. Some problems in dietary amino acid requirements. Am J Clin Nutr. 1968; 21: 367-75.
    • (1968) Am J Clin Nutr , vol.21 , pp. 367-375
    • Holt Jr., L.E.1
  • 19
    • 79955018523 scopus 로고    scopus 로고
    • Regulation of protein metabolism by glutamine: implications for nutrition and health
    • Xi P, Jiang Z, Zheng C, Lin Y, Wu G. Regulation of protein metabolism by glutamine: implications for nutrition and health. Front Biosci. 2011; 16: 578-97.
    • (2011) Front Biosci , vol.16 , pp. 578-597
    • Xi, P.1    Jiang, Z.2    Zheng, C.3    Lin, Y.4    Wu, G.5
  • 20
    • 0024504134 scopus 로고
    • Dizikes, Spector EB, Strickland AD, Klein D, Cedrebaum SD. Differential expression of the two human arginase genes in hyperargininemia. Enzymatic, pathologic and molecular analysis
    • Groody WW, Argyle C, Kern RM. Dizikes, Spector EB, Strickland AD, Klein D, Cedrebaum SD. Differential expression of the two human arginase genes in hyperargininemia. Enzymatic, pathologic and molecular analysis. J Clin Invest. 1989; 83: 602-9.
    • (1989) J Clin Invest , vol.83 , pp. 602-609
    • Groody, W.W.1    Argyle, C.2    Kern, R.M.3
  • 21
    • 79957557558 scopus 로고    scopus 로고
    • To give or not to give? Lessons from arginine paradox
    • doi: 10. 1159/000327777
    • Dioguardi FS. To give or not to give? Lessons from arginine paradox. J Nutrigen Nutrigenom. 2011. doi: 10. 1159/000327777.
    • (2011) J Nutrigen Nutrigenom
    • Dioguardi, F.S.1
  • 22
    • 0009458161 scopus 로고
    • Optimal nutrition correlated with nitrogen retention
    • Allison JB. Optimal nutrition correlated with nitrogen retention. Am J Clin Nutr. 1956; 4: 662-72.
    • (1956) Am J Clin Nutr , vol.4 , pp. 662-672
    • Allison, J.B.1
  • 23
    • 0023390044 scopus 로고
    • Amino acid requirements in the adult human: how well do we know them?
    • Young VR, Bier DM. Amino acid requirements in the adult human: how well do we know them? J Nutr. 1987; 117: 1484-7.
    • (1987) J Nutr , vol.117 , pp. 1484-1487
    • Young, V.R.1    Bier, D.M.2
  • 24
    • 0036313574 scopus 로고    scopus 로고
    • Mechanism of amino acid-induced skeletal muscle insulin resistance in humans
    • Krebs M, Krssak M, Bernroider E, et al. Mechanism of amino acid-induced skeletal muscle insulin resistance in humans. Diabetes. 2002; 51: 599-605.
    • (2002) Diabetes , vol.51 , pp. 599-605
    • Krebs, M.1    Krssak, M.2    Bernroider, E.3
  • 25
    • 67651071908 scopus 로고    scopus 로고
    • The alanine-arginine connection: a key piece in the puzzle of protein renal toxicity, low-protein diets, and the risk of malnutrition in patients with chronic kidney disease
    • Dioguardi FS. The alanine-arginine connection: a key piece in the puzzle of protein renal toxicity, low-protein diets, and the risk of malnutrition in patients with chronic kidney disease. Nutr Ther & Metab. 2009. 27, 1, pp.
    • (2009) Nutr Ther & Metab , vol.27 , pp. 1
    • Dioguardi, F.S.1
  • 26
    • 1942484843 scopus 로고    scopus 로고
    • Wasting and the substrate-to-energy controlled pathway: a role for insulin resistance and amino acids
    • Dioguardi FS. Wasting and the substrate-to-energy controlled pathway: a role for insulin resistance and amino acids. Am J Cardiol. 2004; 93: 6A-12A.
    • (2004) Am J Cardiol , vol.93
    • Dioguardi, F.S.1
  • 27
    • 33747460393 scopus 로고    scopus 로고
    • Chronic oral administration of arginine induces GH gene expression and insulin resistance
    • De Castro Barbosa T, Lourenço Poyares L, Fabres Machado U, Nunes MT. Chronic oral administration of arginine induces GH gene expression and insulin resistance. Life Sci. 2006; 79: 1444-9.
    • (2006) Life Sci , vol.79 , pp. 1444-1449
    • de Castro Barbosa, T.1    Lourenço Poyares, L.2    Fabres Machado, U.3    Nunes, M.T.4
  • 28
    • 78651277159 scopus 로고    scopus 로고
    • A novel amino acids oral supplementation in hemodialysis patients: a pilot study
    • Bolasco P, Caria S, Cupisti A, Secci R, Dioguardi FS. A novel amino acids oral supplementation in hemodialysis patients: a pilot study. Ren Fail. 2011; 33: 1-5.
    • (2011) Ren Fail , vol.33 , pp. 1-5
    • Bolasco, P.1    Caria, S.2    Cupisti, A.3    Secci, R.4    Dioguardi, F.S.5
  • 29
    • 44449084604 scopus 로고    scopus 로고
    • Nutritional supplements with oral amino acid mixtures increases whole-body lean mass and insulin sensitivity in elderly subjects with sarcopenia
    • Solerte SB, Gazzaruso C, Bonacasa R, Rondanelli M, Zamboni M, Basso C, et al. Nutritional supplements with oral amino acid mixtures increases whole-body lean mass and insulin sensitivity in elderly subjects with sarcopenia. Am J Cardiol. 2008; 101: 69E-77E.
    • (2008) Am J Cardiol , vol.101
    • Solerte, S.B.1    Gazzaruso, C.2    Bonacasa, R.3    Rondanelli, M.4    Zamboni, M.5    Basso, C.6
  • 30
    • 44449172228 scopus 로고    scopus 로고
    • Improvement of blood glucose control and insulin sensitivity during a long-term (60 weeks) randomized study with amino acid dietary supplements in elderly subjects with type 2 diabetes mellitus
    • Solerte SB, Fioravanti M, Locatelli E, Bonacasa R, Zamboni M, Basso C, et al. Improvement of blood glucose control and insulin sensitivity during a long-term (60 weeks) randomized study with amino acid dietary supplements in elderly subjects with type 2 diabetes mellitus. Am J Cardiol. 2008; 101: 82E-8E.
    • (2008) Am J Cardiol , vol.101
    • Solerte, S.B.1    Fioravanti, M.2    Locatelli, E.3    Bonacasa, R.4    Zamboni, M.5    Basso, C.6
  • 31
    • 79551570604 scopus 로고    scopus 로고
    • Metabolic and clinical effects of the supplementation of a functional mixture of amino acids in critically ill patients: a pilot study
    • doi:10.1007/s12028-010-9461-z
    • Laviano A, Aghilone F, Colagiovanni D, Fiandra F, Giambarresi R, Tordiglione P, et al. Metabolic and clinical effects of the supplementation of a functional mixture of amino acids in critically ill patients: a pilot study. Neurocritical Care. 2011; 14: 44-9. doi: 10. 1007/s12028-010-9461-z.
    • (2011) Neurocritical Care , vol.14 , pp. 44-49
    • Laviano, A.1    Aghilone, F.2    Colagiovanni, D.3    Fiandra, F.4    Giambarresi, R.5    Tordiglione, P.6
  • 32
    • 79953106636 scopus 로고    scopus 로고
    • Effects of oral amino acid supplementation on long-term-care-acquired infections in elderly patients
    • doi: 10. 1016/j. archger. 2010. 09. 005
    • Aquilani R, Zuccarelli GC, Dioguardi FS, Baiardi P, Frustaglia A, Rutili C, et al. Effects of oral amino acid supplementation on long-term-care-acquired infections in elderly patients. Arch Gerontol Geriatr. 2010. doi: 10. 1016/j. archger. 2010. 09. 005.
    • (2010) Arch Gerontol Geriatr
    • Aquilani, R.1    Zuccarelli, G.C.2    Dioguardi, F.S.3    Baiardi, P.4    Frustaglia, A.5    Rutili, C.6
  • 34
    • 54749098847 scopus 로고    scopus 로고
    • Expanded approach to tolerable upper intake guidelines for nutrients and bioactive substances
    • Jn H, Shao A. Expanded approach to tolerable upper intake guidelines for nutrients and bioactive substances. J Nutr. 2008; 38: 1992S-5S.
    • (2008) J Nutr , vol.38
    • Jn, H.1    Shao, A.2
  • 35
    • 2642542545 scopus 로고    scopus 로고
    • Establishing the upper end of the range of adequate and safe intakes for amino acids: a toxicologist's viewpoint
    • Renwick AG. Establishing the upper end of the range of adequate and safe intakes for amino acids: a toxicologist's viewpoint. J Nutr. 2004; 134: 1617S-24S.
    • (2004) J Nutr , vol.134
    • Renwick, A.G.1
  • 36
    • 0021201587 scopus 로고
    • Adverse effects of excessive consumption of amino acids
    • Benevenga NJ, Steele RD. Adverse effects of excessive consumption of amino acids. Annu Rev Nutr. 1984; 4: 157-81.
    • (1984) Annu Rev Nutr , vol.4 , pp. 157-181
    • Benevenga, N.J.1    Steele, R.D.2
  • 37
    • 41949114267 scopus 로고    scopus 로고
    • Risk assessment for the amino acids taurine, l-glutamine and l-arginine
    • Shao A, Hathcock JN. Risk assessment for the amino acids taurine, l-glutamine and l-arginine. Regul Toxicol Pharmacol. 2008; 50: 376-99.
    • (2008) Regul Toxicol Pharmacol , vol.50 , pp. 376-399
    • Shao, A.1    Hathcock, J.N.2
  • 38
    • 0015127989 scopus 로고
    • Effect of excess levels of individual amino acids on growth of rats fed casein diets
    • Muramatsu K, Odagiri H, Morishita S, Takeuchi H. Effect of excess levels of individual amino acids on growth of rats fed casein diets. J Nutr. 1971; 101: 1117-26.
    • (1971) J Nutr , vol.101 , pp. 1117-1126
    • Muramatsu, K.1    Odagiri, H.2    Morishita, S.3    Takeuchi, H.4
  • 39
    • 0037022926 scopus 로고    scopus 로고
    • Homocysteine induces 3-hydroxy-3-methyl-glutaryl coenzyme A (HMGCoA) reductase in vascular endothelial cells. A mechanism for development of atherosclerosis?
    • Li H, Lewis A, Brodsky S, Rieger R, Iden C, Goligorsky MS. Homocysteine induces 3-hydroxy-3-methyl-glutaryl coenzyme A (HMGCoA) reductase in vascular endothelial cells. A mechanism for development of atherosclerosis? Circulation. 2002; 105: 1037-43.
    • (2002) Circulation , vol.105 , pp. 1037-1043
    • Li, H.1    Lewis, A.2    Brodsky, S.3    Rieger, R.4    Iden, C.5    Goligorsky, M.S.6
  • 41
    • 0032499024 scopus 로고    scopus 로고
    • Homocysteine and atherothrombosis
    • Welch GN, Loscalzo J. Homocysteine and atherothrombosis. N Engl J Med. 1998; 338: 1042-50.
    • (1998) N Engl J Med , vol.338 , pp. 1042-1050
    • Welch, G.N.1    Loscalzo, J.2
  • 42
    • 33644852813 scopus 로고    scopus 로고
    • Arginine: beyond protein
    • Morris SM. Arginine: beyond protein. Am J Clin Nutr. 2006; 83: 508s-12s.
    • (2006) Am J Clin Nutr , vol.83
    • Morris, S.M.1
  • 43
    • 33646788784 scopus 로고    scopus 로고
    • Pathophysiological consequences of homocysteine excess
    • Jakubowski H. Pathophysiological consequences of homocysteine excess. J Nutr. 2006; 136: 1741S-9S.
    • (2006) J Nutr , vol.136
    • Jakubowski, H.1
  • 45
    • 29944434110 scopus 로고    scopus 로고
    • L-Arginine therapy in acute myocardial infarction. The vascular interaction with age in myocardial infarction (VINTAGE MI) randomized trial
    • Schulman SP, Becker LC, Kass DA, Champion HC, Terrin ML, Forman S, et al. L-Arginine therapy in acute myocardial infarction. The vascular interaction with age in myocardial infarction (VINTAGE MI) randomized trial. JAMA. 2006; 295: 58-64.
    • (2006) Jama , vol.295 , pp. 58-64
    • Schulman, S.P.1    Becker, L.C.2    Kass, D.A.3    Champion, H.C.4    Terrin, M.L.5    Forman, S.6
  • 46
    • 0030866605 scopus 로고    scopus 로고
    • Insulin and the arginine paradox
    • Kurz S, Harrison DG. Insulin and the arginine paradox. J Clin Invest. 1997; 99: 369-70.
    • (1997) J Clin Invest , vol.99 , pp. 369-370
    • Kurz, S.1    Harrison, D.G.2
  • 48
    • 27944511437 scopus 로고    scopus 로고
    • Glutamine: a double edged sword in the intensive care unit?
    • Bracco D. Glutamine: a double edged sword in the intensive care unit? Crit Care Med. 2005; 33: 2692-4.
    • (2005) Crit Care Med , vol.33 , pp. 2692-2694
    • Bracco, D.1
  • 49
    • 34249812965 scopus 로고    scopus 로고
    • Glutamine directly downregulates glutamine synthetase protein levels in mouse C2C12 skeletal muscle myotubes
    • Huang Y-F, Wang Y, Watford M. Glutamine directly downregulates glutamine synthetase protein levels in mouse C2C12 skeletal muscle myotubes. J Nutr. 2007; 137: 1357-62.
    • (2007) J Nutr , vol.137 , pp. 1357-1362
    • Huang, Y.-F.1    Wang, Y.2    Watford, M.3
  • 50
    • 78649443324 scopus 로고    scopus 로고
    • Role of glutamine administration on cellular immunity after total parenteral nutrition enriched with glutamine in patients with systemic inflammatory response syndrome
    • 661.e
    • Cetinbas F, Yelken B, Gulbas Z. Role of glutamine administration on cellular immunity after total parenteral nutrition enriched with glutamine in patients with systemic inflammatory response syndrome. J Crit Care. 2010; 25: 661. e1-6.
    • (2010) J Crit Care , vol.25 , pp. 1-6
    • Cetinbas, F.1    Yelken, B.2    Gulbas, Z.3
  • 52
    • 0017690290 scopus 로고
    • Urea bisosynthesis I. The urea cycle and relationships to the citric acid cycle
    • Shambaugh GE. Urea bisosynthesis I. The urea cycle and relationships to the citric acid cycle. Am J Clin Nutr. 1977; 30: 2083-7.
    • (1977) Am J Clin Nutr , vol.30 , pp. 2083-2087
    • Shambaugh, G.E.1
  • 53
    • 84862865537 scopus 로고    scopus 로고
    • Ethical guidelines for authorship and publishing in the Journal of Cachexia, Sarcopenia and Muscle
    • von Haehling S, Morley JE, Coats AJ, Anker SD. Ethical guidelines for authorship and publishing in the Journal of Cachexia, Sarcopenia and Muscle. J Cachexia Sarcopenia Muscle. 2010; 1: 7-8.
    • (2010) J Cachexia Sarcopenia Muscle , vol.1 , pp. 7-8
    • von Haehling, S.1    Morley, J.E.2    Coats, A.J.3    Anker, S.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.