Pro-inflammatory effects of ochratoxin A on nasal epithelial cells

European Archives of Oto-Rhino-Laryngology

Volumn 269, Issue 4, 2012, Pages 1155-1161

  Cremer, Birgit ^a   Soja, Alexandra ^a   Sauer, Jan Alex ^a   Damm, Michael ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Chronic rhinosinusitis; Eosinophilic chronic rhinosinusitis; Interleukin 6; Interleukin 8; Mycotoxin; Ochratoxin A

Indexed keywords

INTERLEUKIN 6; INTERLEUKIN 8; OCHRATOXIN;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; HUMAN; HUMAN CELL; INFLAMMATION; NOSE MUCOSA; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SUPERNATANT;

CARCINOGENS; CELLS, CULTURED; CHRONIC DISEASE; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIAL CELLS; HUMANS; INFLAMMATION; MYCOTOXINS; NASAL MUCOSA; OCHRATOXINS; RHINITIS; SINUSITIS;

EID: 84862834138     PISSN: 09374477     EISSN: 14344726     Source Type: Journal    
DOI: 10.1007/s00405-011-1820-7     Document Type: Article

References (37)

1. Meltzer EO, Hamilos DL, Hadley JA, Lanza DC, Marple BF, Nicklas RA, Bachert C, Baraniuk J, Baroody FM, Benninger MS, Brook I, Chowdhury BA, Druce HM, Durham S, Ferguson B, Gwaltney JM, Kaliner M, Kennedy DW, Lund V, Naclerio R, Pawankar R, Piccirillo JF, Rohane P, Simon R, Slavin RG, Togias A, Wald ER, Zinreich SJ (2004) Rhinosinusitis: establishing definitions for clinical research and patient care. J Allergy Clin Immunol 114 (6 Suppl):155-212
2. Sok JC, Ferguson BJ (2006) Differential diagnosis of eosinophilic chronic rhinosinusitis. Curr Allergy Asthma Rep 6 (3):203-214
3. Benninger MS, Ferguson BJ, Hadley JA, Hamilos DL, Jacobs M, Kennedy DW, Lanza DC, Marple BF, Osguthorpe JD, Stankiewicz JA, Anon J, Denneny J, Emanuel I, Levine H (2003) Adult chronic rhinosinusitis: definitions, diagnosis, epidemiology, and pathophysiology. Otolaryngol Head Neck Surg 129 (3 Suppl):S1-S32
4. de Shazo RD, Chapin K, Swain RE (1997) Fungal sinusitis. N Engl J Med 337 (4):254-259
5. Bent JP III, Kuhn FA (1994) Diagnosis of allergic fungal sinusitis. Otolaryngol Head Neck Surg 111 (5):580-588
6. Schubert MS (2009) Allergic fungal sinusitis: pathophysiology, diagnosis and management. Med Mycol 47 (Suppl 1):S324-S330
7. Taylor MJ, Ponikau JU, Sherris DA, Kern EB, Gaffey TA, Kephart G, Kita H (2002) Detection of fungal organisms in eosinophilic mucin using a fluorescein-labeled chitin-specific binding protein. Otolaryngol Head Neck Surg 127 (5):377-383
8. Ponikau JU, Sherris DA, Kern EB, Homburger HA, Frigas E, Gaffey TA, Roberts GD (1999) The diagnosis and incidence of allergic fungal sinusitis. Mayo Clin Proc 74 (9):877-884
9. Braun H, Buzina W, Freudenschuss K, Beham A, Stammberger A (2003) 'Eosinophilic fungal rhinosinusitis': a common disorder in Europe? Laryngoscope 113 (2):264-269
10. Shin SH, Ponikau JU, Sherris DA, Congdon D, Frigas E, Homburger HA, Swanson MC, Gleich GJ, Kita H (2004) Chronic rhinosinusitis: an enhanced immune response to ubiquitous airborne fungi. J Allergy Clin Immunol 114 (6):1369-1375
11. Okano M, Fujiwara T, Haruna T, Kariya S, Makihara S, Higaki T, Nishizaki K (2011) Role of fungal antigens in eosinophiliaassociated cellular responses in nasal polyps: a comparison with enterotoxin. Clin Exp Allergy 41 (2):171-178
12. Damm M, Quante G, Rosenbohm J, Rieckmann R (2006) Proinflammatory effects of Staphylococcus aureus exotoxin B on nasal epithelial cells. Otolaryngol Head Neck Surg 134 (2):245-249
13. Bennett JW, Klich M (2003) Mycotoxins. Clin Microbiol Rev 16 (3):497-516
14. van der Merwe KJ, Steyn PS, Fourie L, Scott DB, Theron JJ (1965) Ochratoxin A, a toxic metabolite produced by Aspergillus ochraceus Wilh. Nature 205 (976):1112-1113
15. Al-Anati L, Petzinger E (2006) Immunotoxic activity of ochratoxin A. J Vet Pharmacol Ther 29 (2):79-90
16. Richard JL, Plattner RD, May J, Liska SL (1999) The occurrence of ochratoxin A in dust collected from a problem household. Mycopathologia 146 (2):99-103
17. Skaug MA, Eduard W, Stormer FC (2001) Ochratoxin A in airborne dust and fungal conidia. Mycopathologia 151 (2):93-98
18. Kobayashi T, Iijima K, Radhakrishnan S, Mehta V, Vassallo R, Lawrence CB, Cyong JC, Pease LR, Oguchi K, Kita H (2009)Asthma-related environmental fungus, Alternaria, activates dendritic cells and produces potent Th2 adjuvant activity. J Immunol 182 (4):2502-2510
19. Inoue Y, Matsuwaki Y, Shin SH, Ponikau JU, Kita H (2005) Nonpathogenic, environmental fungi induce activation and degranulation of human eosinophils. J Immunol 175 (8):5439-5447
20. Maresca M, Yahi N, Younes-Sakr L, Boyron M, Caporiccio B, Fantini J (2008) Both direct and indirect effects account for the pro-inflammatory activity of enteropathogenic mycotoxins on the human intestinal epithelium: stimulation of interleukin-8 secretion, potentiation of interleukin-1beta effect and increase in the transepithelial passage of commensal bacteria. Toxicol Appl Pharmacol 228 (1):84-92
21. Bradley DT, Kountakis SE (2005) Role of interleukins and transforming growth factor-beta in chronic rhinosinusitis and nasal polyposis. Laryngoscope 115 (4):684-686
22. Ghaffar O, Lavigne F, Kamil A, Renzi P, Hamid Q (1998) Interleukin-6 expression in chronic sinusitis: colocalization of gene transcripts to eosinophils, macrophages, T lymphocytes, and mast cells. Otolaryngol Head Neck Surg 118 (4):504-511
23. Peters AT, Kato A, Zhang N, Conley DB, Suh L, Tancowny B, Carter D, Carr T, Radtke M, Hulse KE, Seshadri S, Chandra R, Grammer LC, Harris KE, Kern R, Schleimer RP (2010) Evidence for altered activity of the IL-6 pathway in chronic rhinosinusitis with nasal polyps. J Allergy Clin Immunol 125 (2):397-403
24. Davidsson A, Danielsen A, Viale G, Olofsson J, Dell'Orto P, Pellegrini C, Karlsson MG, Hellquist HB (1996) Positive identification in situ of mRNA expression of IL-6, and IL-12, and the chemotactic cytokine RANTES in patients with chronic sinusitis and polypoid disease. Clinical relevance and relation to allergy. Acta Otolaryngol 116 (4):604-610
25. Min YG, Lee CH, Rhee CS, Hong SK, Kwon SH (1999) Increased expression of IL-4, IL-5, IFN-gamma, IL-6, IL-8, and TGF-beta mRNAs in maxillary mucosa of patients with chronic sinusitis. Am J Rhinol 13 (5):339-343
26. Nonoyama T, Harada T, Shinogi J, Yoshimura E, Sakakura Y (2000) Immunohistochemical localization of cytokines and cell adhesion molecules in maxillary sinus mucosa in chronic sinusitis. Auris Nasus Larynx 27 (1):51-58
27. Anand VK, Kacker A, Orjuela AF, Huang C, Manarey C, Xiang J (2006) Inflammatory pathway gene expression in chronic rhinosinusitis. Am J Rhinol 20 (4):471-476
28. Danielsen A, Tynning T, Brokstad KA, Olofsson J, Davidsson A (2006) Interleukin 5, IL6, IL12, IFN-gamma, RANTES and Fractalkine in human nasal polyps, turbinate mucosa and serum. Eur Arch Otorhinolaryngol 263 (3):282-289
29. Mukaida N (2003) Pathophysiological roles of interleukin-8/ CXCL8 in pulmonary diseases. Am J Physiol Lung Cell Mol Physiol 284 (4):L566-L577
30. Middleton J, Neil S, Wintle J, Clark-Lewis I, Moore H, Lam C, Auer M, Hub E, Rot A (1997) Transcytosis and surface presentation of IL-8 by venular endothelial cells. Cell 91 (3):385-395
31. Mul FP, Zuurbier AE, Janssen H, Calafat J, van Wetering S, Hiemstra PS, Roos D, Hordijk PL (2000) Sequential migration of neutrophils across monolayers of endothelial and epithelial cells. J Leukoc Biol 68 (4):529-537
32. Peterson ML, Ault K, Kremer MJ, Klingelhutz AJ, Davis CC, Squier CA, Schlievert PM (2005) The innate immune system is activated by stimulation of vaginal epithelial cells with Staphylococcus aureus and toxic shock syndrome toxin 1. Infect Immun73 (4):2164-2174
33. Suzuki H, Takahashi Y, Wataya H, Ikeda K, Nakabayashi S, Shimomura A, Takasaka T (1996) Mechanism of neutrophil recruitment induced by IL-8 in chronic sinusitis. J Allergy Clin Immunol 98 (3):659-670
34. Takeuchi K, Yuta A, Sakakura Y (1995) Interleukin-8 gene expression in chronic sinusitis. Am J Otolaryngol 16 (2):98-102
35. Otto BA, Wenzel SE (2008) The role of cytokines in chronic rhinosinusitis with nasal polyps. Curr Opin Otolaryngol Head Neck Surg 16 (3):270-274
36. Kenney JS, Baker C, Welch MR, Altman LC (1994) Synthesis of interleukin-1 alpha, interleukin-6, and interleukin-8 by cultured human nasal epithelial cells. J Allergy Clin Immunol 93 (6): 1060-1067
37. Rosenfeld RM, Andes D, Bhattacharyya N, Cheung D, Eisenberg S, Ganiats TG, Gelzer A, Hamilos D, Haydon RC 3rd, Hudgins PA, Jones S, Krouse HJ, Lee LH, Mahoney MC, Marple BF, Mitchell CJ, Nathan R, Shiffman RN, Smith TL, Witsell DL (2007) Clinical practice guideline: adult sinusitis. Otolaryngol Head Neck Surg 137 (3 Suppl):S1-S31