Interleukin 5, IL6, IL12, IFN-γ, RANTES and Fractalkine in human nasal polyps, turbinate mucosa and serum

European Archives of Oto-Rhino-Laryngology

Volumn 263, Issue 3, 2006, Pages 282-289

  Danielsen, Arild ^a,c,d   Tynning, Turid ^d   Brokstad, Karl A ^d   Olofsson, Jan ^c   Davidsson, Åke ^b,c,d  

^a Department of Otorhinolaryngology   (Norway)

^b ÖREBRO UNIVERSITY HOSPITAL   (Sweden)

^c HAUKELAND UNIVERSITY HOSPITAL   (Norway)

^d UNIVERSITY OF BERGEN   (Norway)

Author keywords

Chemokines; Cytokines; Inflammatory mechanisms; Nasal polyp

Indexed keywords

CHEMOKINE; CYTOKINE; FRACTALKINE; GAMMA INTERFERON; INTERLEUKIN 5; INTERLEUKIN 6; RANTES;

ADULT; AGED; ARTICLE; BLOOD LEVEL; CLINICAL ARTICLE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FIBROBLAST; HUMAN; INFLAMMATION; MALE; NOSE POLYP; PATHOPHYSIOLOGY; PRIORITY JOURNAL; SERUM; TH1 CELL; TH2 CELL; TISSUE HOMOGENATE; TURBINATE;

ADULT; AGED; BIOLOGICAL MARKERS; CHEMOKINE CCL5; CYTOKINES; FEMALE; HUMANS; INTERFERON TYPE II; INTERFERON-GAMMA; INTERLEUKINS; MALE; MIDDLE AGED; NASAL MUCOSA; NASAL POLYPS; RANTES; TURBINATES;

EID: 33646444089     PISSN: 09374477     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00405-005-1031-1     Document Type: Article

References (23)

1. Bachert C, Gevaert P (1999) Effect of intranasal corticosteroids on release of cytokines and inflammatory mediators. Allergy [Suppl] 54:23
2. Bachert C, Gevaert P, Holtappels G, Cuvelier C, van Cauwenberge P (2000) Nasal polyposis: from cytokines to growth. Am J Rhinol 14:279-290
3. Bernstein JM (2001) The molecular biology of nasal polyposis. Curr Allergy Asthma Rep 1:262-267
4. Bachert C, Gevaert P, Holtappels G, van Cauwenberge P (2002) Mediators in nasal polyposis. Curr Allergy Asthma Rep 2:481-487
5. Davidsson Å, Danielsen A, Viale G, Olofsson J, Dell'Orto P, Pellegrini C (1996) Positive identification in situ of mRNA expression of IL-6, and IL-12, and the chemotactic cytokine RANTES in patients with chronic sinusitis and polypoid disease. Clinical relevance and relation to allergy. Acta Otolaryngol (Stockh) 116:604-610
6. Bachert C, Wagenmann M, Hauser U, Rudack C (1997) IL-5 synthesis is upregulated in human nasal polyp tissue. J Allergy Clin Immunol 99:42
7. Hamilos DL, Leung DY, Huston DP, Kamil A, Wood R, Hamid Q (1998) GM-CSF, IL-5 and RANTES immunoreactivity and mRNA expression in chronic hyperplastic sinusitis with nasal polyposis (NP). Clin Exp Allergy 28:1145-1152
8. Lee CH, Lee KS, Rhee CS, Lee SO, Min YG (1999) Distribution of Rantes and interleukin-5 in allergic nasal mucosa and nasal polyps. Ann Otol Rhinol Laryngol 108:594-598
9. Rudack C, Bachert C (1999) Cytokines and chemokines in paranasal sinus diseases (German). Laryngorhinootologie 78:481-490
10. Lee CH, Rhee CS, Min YG (1998) Cytokine gene expression in nasal polyps. Ann Otol Rhinol Laryngol 107:665-670
11. Dellacono FR, Eisma R, Lafreniere D, Leonard G, Kreutzer D (1997) Interferon gamma expression in human nasal polyps. Laryngoscope 107:626-630
12. Miller CH, Pudiak DR, Hatem F, Looney RJ (1994) Accumulation of interferon gamma-producing TH1 helper T cells in nasal polyps. Otolaryngol Head Neck Surg 111:51-58
13. Ancuta P, Rao R, Moses A, Mehle A, Shaw SK, Luscinskas FW (2003) Fractalkine preferentially mediates arrest and migration of CD16+ monocytes. J Exp Med 197:1701-1707
14. Hughes PM, Botham MS, Frentzel S, Mir A, Perry VH (2002) Expression of fractalkine (CX3CL1) and its receptor, CX3CR1, during acute and chronic inflammation in the rodent CNS. GLIA 37:314-327
15. Bachert C, Gevaert P, Holtappels G, Johansson SGO, van Cauwenberge P (2001) Total and specific IgE in nasal polyps is related to local eosinophilic inflammation. J Allergy Clin Immunol 107:607-614
16. Bachert C, Van Cauwenberge PB (1997) Inflammatory mechanisms in chronic sinusitis. Acta Otorhinolaryngol Belg 51:209-217
17. Liu CM, Hong CY, Shun CT, Hsiao TY, Wang CC, Wang JS (2002) Inducible cyclooxygenase and interleukin 6 gene expressions in nasal polyp fibroblasts: possible implication in the pathogenesis of nasal polyposis. Arch Otolaryngol Head Neck Surg 128:945-951
18. Hamilos DL, Leung DY, Wood R, Bean DK, Song YL, Schotman E (1996) Eosinophil infiltration in nonallergic chronic hyperplastic sinusitis with nasal polyposis (CHS/NP) is associated with endothelial VCAM-1 upregulation and expression of TNF-alpha. Am J Respir Cell Mol Biol 15:443-450
19. Matsukura S, Kokubu F, Kubo H, Tomita T, Tokunaga H, Kadokura M (1998) Expression of RANTES by normal airway epithelial cells after influenza virus A infection. Am J Respir Cell Mol Biol 18:255-264
20. Maune S, Berner I, Sticherling M, Kulke R, Bartels J, Schroder JM (1996) Fibroblasts but not epithelial cells obtained from human nasal mucosa produce the chemokine RANTES. Rhinology 34:210-214
21. Nonaka M, Pawankar R, Saji F, Yagi T (1999) Distinct expression of RANTES and GM-CSF by lipopolysaccharide in human nasal fibroblasts but not in other airway fibroblasts. Int Arch Allergy Immunol 119:314-321
22. Pawankar R (2003) Nasal polyposis: an update: editorial review. Curr Opin Allergy Clin Immunol 3:1-6
23. Li H, Xu G, Li Y, Xie M, Zhang G (2001) Expression of Th1, Th2-typed cytokines and its significance in nasal polyps (Chinese). Lin Chuang Erh Pi Yen Hou Ko Tsa Chih J Clin Otorhinolaryngol 15:51-52