SNCA polymorphisms, smoking, and sporadic Parkinson's disease in Japanese

Parkinsonism and Related Disorders

Volumn 18, Issue 5, 2012, Pages 557-561

  Miyake, Yoshihiro ^a   Tanaka, Keiko ^a   Fukushima, Wakaba ^b   Kiyohara, Chikako ^c   Sasaki, Satoshi ^d   Tsuboi, Yoshio ^a   Yamada, Tatsuo ^a   Oeda, Tomoko ^e   Shimada, Hiroyuki ^b   Kawamura, Nobutoshi ^c   Sakae, Nobutaka ^c   Fukuyama, Hidenao ^f   Hirota, Yoshio ^b   Nagai, Masaki ^g  

^a FUKUOKA UNIVERSITY   (Japan)

^b OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c KYUSHU UNIVERSITY   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

^e UTANO NATIONAL HOSPITAL   (Japan)

^f KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^g SAITAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

Case control study; Gene environment interaction; Japanese; Parkinson's disease; Smoking; SNCA polymorphisms

Indexed keywords

AGE; AGED; ARTICLE; CIGARETTE SMOKING; CONTROLLED STUDY; FEMALE; GENE; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC MODEL; GENOTYPE; GENOTYPE ENVIRONMENT INTERACTION; HOSPITAL BASED CASE CONTROL STUDY; HUMAN; JAPAN; JAPANESE; MAJOR CLINICAL STUDY; MALE; ONSET AGE; PARKINSON DISEASE; PRIORITY JOURNAL; RECESSIVE MODEL; RESIDENTIAL AREA; SEX; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING HABIT; SNCA GENE;

AGED; ALPHA-SYNUCLEIN; CASE-CONTROL STUDIES; CHI-SQUARE DISTRIBUTION; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; JAPAN; MALE; MIDDLE AGED; PARKINSON DISEASE; POLYMORPHISM, SINGLE NUCLEOTIDE; QUESTIONNAIRES; RETROSPECTIVE STUDIES; SMOKING;

EID: 84862831151     PISSN: 13538020     EISSN: 18735126     Source Type: Journal    
DOI: 10.1016/j.parkreldis.2012.02.016     Document Type: Article

References (32)

1. Nemani V.M., Lu W., Berge V., Nakamura K., Onoa B., Lee M.K., et al. Increased expression of α-synuclein reduces neurotransmitter release by inhibiting synaptic vesicle reclustering after endocytosis. Neuron 2010, 65:66-79.
2. Lee H.J., Kang S.J., Lee K., Im H. Human α-synuclein modulates vesicle trafficking through its interaction with prenylated Rab acceptor protein 1. Biochem Biophys Res Commun 2011, 412:526-531.
3. Dawson T.M., Dawson V.L. Molecular pathways of neurodegeneration in Parkinson's disease. Science 2003, 302:819-822.
4. Polymeropoulos M.H., Lavedan C., Leroy E., Ide S.E., Dehejia A., Dutra A., et al. Mutation in the α-synuclein gene identified in families with Parkinson's disease. Science 1997, 276:2045-2047.
5. Maraganore D.M., de Andrade M., Elbaz A., Farrer M.J., Ioannidis J.P., Krüger R., et al. Collaborative analysis of alpha-synuclein gene promoter variability and Parkinson disease. JAMA 2006, 296:661-670.
6. Pals P., Lincoln S., Manning J., Heckman M., Skipper L., Hulihan M., et al. α-Synuclein promoter confers susceptibility to Parkinson's disease. Ann Neurol 2004, 56:591-595.
7. Mueller J.C., Fuchs J., Hofer A., Zimprich A., Lichtner P., Illig T., et al. Multiple regions of α-synuclein are associated with Parkinson's disease. Ann Neurol 2005, 57:535-541.
8. Mizuta I., Satake W., Nakabayashi Y., Ito C., Suzuki S., Momose Y., et al. Multiple candidate gene analysis identifies α-synuclein as a susceptibility gene for sporadic Parkinson's disease. Hum Mol Genet 2006, 15:1151-1158.
9. Winkler S., Hagenah J., Lincoln S., Heckman M., Haugarvoll K., Lohmann-Hedrich K., et al. α-Synuclein and Parkinson disease susceptibility. Neurology 2007, 69:1745-1750.
10. Ross O.A., Gosal D., Stone J.T., Lincoln S.J., Heckman M.G., Irvine G.B., et al. Familial genes in sporadic disease: common variants of α-synuclein gene associate with Parkinson's disease. Mech Ageing Dev 2007, 128:378-382.
11. Mizuta I., Tsunoda T., Satake W., Nakabayashi Y., Watanabe M., Takeda A., et al. Calbindin 1, fibroblast growth factor 20, and α-synuclein in sporadic Parkinson's disease. Hum Genet 2008, 124:89-94.
12. Myhre R., Toft M., Kachergus J., Hulihan M.M., Aasly J.O., Klungland H., et al. Multiple alpha-synuclein gene polymorphisms are associated with Parkinson's disease in a Norwegian population. Acta Neurol Scand 2008, 118:320-327.
13. Yu L., Xu P., He X., Hu F., Lin Z., Zhu M., et al. SNP rs7684318 of the α-synuclein gene is associated with Parkinson's disease in the Han Chinese population. Brain Res 2010, 1346:262-265.
14. Mata I.F., Shi M., Agarwal P., Chung K.A., Edwards K.L., Factor S.A., et al. SNCA variant associated with Parkinson disease and plasma alpha-synuclein level. Arch Neurol 2010, 67:1350-1356.
15. Mata I.F., Yearout D., Alvarez V., Coto E., de Mena L., Ribacoba R., et al. Replication of MAPT and SNCA, but not PARK16-18, as susceptibility genes for Parkinson's disease. Mov Disord 2011, 26:819-823.
16. Elbaz A., Ross O.A., Ioannidis J.P., Soto-Ortolaza A.I., Moisan F., Aasly J., et al. Independent and joint effects of the MAPT and SNCA genes in Parkinson disease. Ann Neurol 2011, 69:778-792.
17. Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies. Lancet 2011, 377:641-649. International Parkinson Disease Genomics Consortium.
18. Hughes A.J., Daniel S.E., Kilford L., Lees A.J. Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry 1992, 55:181-184.
19. Pankratz N., Wilk J.B., Latourelle J.C., DeStefano A.L., Halter C., Pugh E.W., et al. Genomewide association study for susceptibility genes contributing to familial Parkinson disease. Hum Genet 2009, 124:593-605.
20. Simón-Sánchez J., Schulte C., Bras J.M., Sharma M., Gibbs J.R., Berg D., et al. Genome-wide association study reveals genetic risk underlying Parkinson's disease. Nat Genet 2009, 41:1308-1312.
21. Edwards T.L., Scott W.K., Almonte C., Burt A., Powell E.H., Beecham G.W., et al. Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease. Ann Hum Genet 2010, 74:97-109.
22. Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21. Hum Mol Genet 2011, 20:345-353. UK Parkinson's Disease Consortium, Wellcome Trust Case Control Consortium 2Wellcome Trust Case Control Consortium 2.
23. Saad M., Lesage S., Saint-Pierre A., Corvol J.C., Zelenika D., Lambert J.C., et al. Genome-wide association study confirms BST1 and suggests a locus on 12q24 as the risk loci for Parkinson's disease in the European population. Hum Mol Genet 2011, 20:615-627.
24. Barrett J.C., Fry B., Maller J., Daly M.J. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005, 21:263-265.
25. Gauderman W.J. Sample size requirements for matched case-control studies of gene-environment interaction. Stat Med 2002, 21:35-50.
26. Tanaka K., Miyake Y., Fukushima W., Sasaki S., Kiyohara C., Tsuboi Y., et al. Active and passive smoking and risk of Parkinson's disease. Acta Neurol Scand 2010, 122:377-382.
27. Andersson T., Alfredsson L., Källberg H., Zdravkovic S., Ahlbom A. Calculating measures of biological interaction. Eur J Epidemiol 2005, 20:575-579.
28. Knol M.J., VanderWeele T.J., Groenwold R.H., Klungel O.H., Rovers M.M., Grobbee D.E. Estimating measures of interaction on an additive scale for preventive exposures. Eur J Epidemiol 2011, 26:433-438.
29. Beyer K. α-Synuclein structure, posttranslational modification and alternative splicing as aggregation enhancers. Acta Neuropathol 2006, 112:237-251.
30. McCarthy J.J., Linnertz C., Saucier L., Burke J.R., Hulette C.M., Welsh-Bohmer K.A., et al. The effect of SNCA 3' region on the levels of SNCA-112 splicing variant. Neurogenetics 2011, 12:59-64.
31. Ahlbom A., Alfredsson L. Interaction: a word with two meanings creates confusion. Eur J Epidemiol 2005, 20:563-564.
32. Miyake Y. Risk factors for non-fatal acute myocardial infarction in middle-aged and older Japanese. Jpn Circ J 2000, 64:103-109. Fukuoka Heart Study Group.