-
1
-
-
0030744876
-
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease
-
Polymeropoulos MH, Lavedan C, Leroy E et al. Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science 1997 276 : 2045 7.
-
(1997)
Science
, vol.276
, pp. 2045-7
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
-
2
-
-
0031990490
-
Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease
-
Kruger R, Kuhn W, Muller T et al. Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease. Nat Genet 1998 18 : 106 8.
-
(1998)
Nat Genet
, vol.18
, pp. 106-8
-
-
Kruger, R.1
Kuhn, W.2
Muller, T.3
-
3
-
-
10744230149
-
The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia
-
Zarranz JJ, Alegre J, Gomez-Esteban JC et al. The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia. Ann Neurol 2004 55 : 164 73.
-
(2004)
Ann Neurol
, vol.55
, pp. 164-73
-
-
Zarranz, J.J.1
Alegre, J.2
Gomez-Esteban, J.C.3
-
4
-
-
6844236385
-
Sequencing of the alpha-synuclein gene in a large series of cases of familial Parkinson's disease fails to reveal any further mutations. the European Consortium on Genetic Susceptibility in Parkinson's Disease (GSPD)
-
Vaughan JR, Farrer MJ, Wszolek ZK et al. Sequencing of the alpha-synuclein gene in a large series of cases of familial Parkinson's disease fails to reveal any further mutations. The European Consortium on Genetic Susceptibility in Parkinson's Disease (GSPD). Hum Mol Genet 1998 7 : 751 3.
-
(1998)
Hum Mol Genet
, vol.7
, pp. 751-3
-
-
Vaughan, J.R.1
Farrer, M.J.2
Wszolek, Z.K.3
-
5
-
-
4043182729
-
Alpha-synuclein missense and multiplication mutations in autosomal dominant Parkinson's disease
-
97-100.
-
Hope AD, Myhre R, Kachergus J et al. Alpha-synuclein missense and multiplication mutations in autosomal dominant Parkinson's disease. Neurosci Lett 2004 26 : 367. 97-100.
-
(2004)
Neurosci Lett
, vol.26
, pp. 367
-
-
Hope, A.D.1
Myhre, R.2
Kachergus, J.3
-
6
-
-
27744553995
-
Alpha-synuclein and Parkinson's disease: Implications from the screening of more than 1,900 patients
-
Berg D, Niwar M, Maass S et al. Alpha-synuclein and Parkinson's disease: implications from the screening of more than 1,900 patients. Mov Disord 2005 20 : 1191 4.
-
(2005)
Mov Disord
, vol.20
, pp. 1191-4
-
-
Berg, D.1
Niwar, M.2
Maass, S.3
-
7
-
-
0030882856
-
Alpha-synuclein in Lewy bodies
-
Spillantini MG, Schmidt ML, Lee VM, Trojanowski JQ, Jakes R, Goedert M. Alpha-synuclein in Lewy bodies. Nature 1997 388 : 839 40.
-
(1997)
Nature
, vol.388
, pp. 839-40
-
-
Spillantini, M.G.1
Schmidt, M.L.2
Lee, V.M.3
Trojanowski, J.Q.4
Jakes, R.5
Goedert, M.6
-
8
-
-
0242300619
-
Alpha-synuclein locus triplication causes Parkinson's disease
-
Singleton AB, Farrer M, Johnson J et al. Alpha-synuclein locus triplication causes Parkinson's disease. Science 2003 302 : 841.
-
(2003)
Science
, vol.302
, pp. 841
-
-
Singleton, A.B.1
Farrer, M.2
Johnson, J.3
-
9
-
-
4644290985
-
Alpha-synuclein locus duplication as a cause of familial Parkinson's disease
-
Chartier-Harlin MC, Kachergus J, Roumier C et al. Alpha-synuclein locus duplication as a cause of familial Parkinson's disease. Lancet 2004 364 : 1167 9.
-
(2004)
Lancet
, vol.364
, pp. 1167-9
-
-
Chartier-Harlin, M.C.1
Kachergus, J.2
Roumier, C.3
-
10
-
-
34147109175
-
Phenotypic variation in a large Swedish pedigree due to SNCA duplication and triplication
-
Fuchs J, Nilsson C, Kachergus J et al. Phenotypic variation in a large Swedish pedigree due to SNCA duplication and triplication. Neurology 2007 68 : 916 22.
-
(2007)
Neurology
, vol.68
, pp. 916-22
-
-
Fuchs, J.1
Nilsson, C.2
Kachergus, J.3
-
11
-
-
0037426704
-
Alpha synuclein promoter and risk of Parkinson's disease: Microsatellite and allelic size variability
-
Tan EK, Tan C, Shen H et al. Alpha synuclein promoter and risk of Parkinson's disease: microsatellite and allelic size variability. Neurosci Lett 2003 336 : 70 2.
-
(2003)
Neurosci Lett
, vol.336
, pp. 70-2
-
-
Tan, E.K.1
Tan, C.2
Shen, H.3
-
12
-
-
9144266292
-
Alpha-synuclein haplotypes implicated in risk of Parkinson's disease
-
Tan EK, Chai A, Teo YY et al. Alpha-synuclein haplotypes implicated in risk of Parkinson's disease. Neurology 2004 62 : 128 31.
-
(2004)
Neurology
, vol.62
, pp. 128-31
-
-
Tan, E.K.1
Chai, A.2
Teo, Y.Y.3
-
13
-
-
0342950666
-
Increased susceptibility to sporadic Parkinson's disease by a certain combined alpha-synuclein/apolipoprotein e genotype
-
Kruger R, Vieira-Saecker AM, Kuhn W et al. Increased susceptibility to sporadic Parkinson's disease by a certain combined alpha-synuclein/ apolipoprotein E genotype. Ann Neurol 1999 45 : 611 17.
-
(1999)
Ann Neurol
, vol.45
, pp. 611-17
-
-
Kruger, R.1
Vieira-Saecker, A.M.2
Kuhn, W.3
-
14
-
-
0035831303
-
Genetic studies in Parkinson's disease with an alpha-synuclein/NACP gene polymorphism in Japan
-
Izumi Y, Morino H, Oda M et al. Genetic studies in Parkinson's disease with an alpha-synuclein/NACP gene polymorphism in Japan. Neurosci Lett 2001 300 : 125 7.
-
(2001)
Neurosci Lett
, vol.300
, pp. 125-7
-
-
Izumi, Y.1
Morino, H.2
Oda, M.3
-
15
-
-
18544406092
-
Parkinson's disease is not associated with the combined alpha-synuclein/apolipoprotein e susceptibility genotype
-
Khan N, Graham E, Dixon P et al. Parkinson's disease is not associated with the combined alpha-synuclein/apolipoprotein E susceptibility genotype. Ann Neurol 2001 49 : 665 8.
-
(2001)
Ann Neurol
, vol.49
, pp. 665-8
-
-
Khan, N.1
Graham, E.2
Dixon, P.3
-
16
-
-
10744223645
-
NACP-REP1 polymorphism is not involved in Parkinson's disease: A case-control study in a population sample from southern Italy
-
Spadafora P, Annesi G, Pasqua AA et al. NACP-REP1 polymorphism is not involved in Parkinson's disease: a case-control study in a population sample from southern Italy. Neurosci Lett 2003 351 : 75 8.
-
(2003)
Neurosci Lett
, vol.351
, pp. 75-8
-
-
Spadafora, P.1
Annesi, G.2
Pasqua, A.A.3
-
17
-
-
33746869343
-
Collaborative analysis of alpha-synuclein gene promoter variability and Parkinson disease
-
Maraganore DM, de Andrade M, Elbaz A et al. Collaborative analysis of alpha-synuclein gene promoter variability and Parkinson disease. JAMA 2006 296 : 661 70.
-
(2006)
JAMA
, vol.296
, pp. 661-70
-
-
Maraganore, D.M.1
De Andrade, M.2
Elbaz, A.3
-
18
-
-
4844222408
-
Alpha-synuclein promoter confers susceptibility to Parkinson's disease
-
Pals P, Lincoln S, Manning J et al. Alpha-synuclein promoter confers susceptibility to Parkinson's disease. Ann Neurol 2004 56 : 591 5.
-
(2004)
Ann Neurol
, vol.56
, pp. 591-5
-
-
Pals, P.1
Lincoln, S.2
Manning, J.3
-
19
-
-
20144387092
-
Multiple regions of alpha-synuclein are associated with Parkinson's disease
-
Mueller JC, Fuchs J, Hofer A et al. Multiple regions of alpha-synuclein are associated with Parkinson's disease. Ann Neurol 2005 57 : 535 41.
-
(2005)
Ann Neurol
, vol.57
, pp. 535-41
-
-
Mueller, J.C.1
Fuchs, J.2
Hofer, A.3
-
20
-
-
33645111633
-
Multiple candidate gene analysis identifies alpha-synuclein as a susceptibility gene for sporadic Parkinson's disease
-
Mizuta I, Satake W, Nakabayashi Y et al. Multiple candidate gene analysis identifies alpha-synuclein as a susceptibility gene for sporadic Parkinson's disease. Hum Mol Genet 2006 15 : 1151 8.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 1151-8
-
-
Mizuta, I.1
Satake, W.2
Nakabayashi, Y.3
-
21
-
-
0029163049
-
The epidemiology of Parkinson's disease in the county of Rogaland, Norway
-
Tandberg E, Larsen JP, Nessler EG, Riise T, Aarli JA. The epidemiology of Parkinson's disease in the county of Rogaland, Norway. Mov Disord 1995 10 : 541 9.
-
(1995)
Mov Disord
, vol.10
, pp. 541-9
-
-
Tandberg, E.1
Larsen, J.P.2
Nessler, E.G.3
Riise, T.4
Aarli, J.A.5
-
22
-
-
10744227740
-
Comparison of kindreds with Parkinsonism and alpha-synuclein genomic multiplications
-
Farrer M, Kachergus J, Forno L et al. Comparison of kindreds with Parkinsonism and alpha-synuclein genomic multiplications. Ann Neurol 2004 55 : 174 9.
-
(2004)
Ann Neurol
, vol.55
, pp. 174-9
-
-
Farrer, M.1
Kachergus, J.2
Forno, L.3
-
23
-
-
4043055593
-
Multiplication of the alpha-synuclein gene is not a common disease mechanism in Lewy body disease
-
Lockhart PJ, Kachergus J, Lincoln S et al. Multiplication of the alpha-synuclein gene is not a common disease mechanism in Lewy body disease. J Mol Neurosci 2004 24 : 337 42.
-
(2004)
J Mol Neurosci
, vol.24
, pp. 337-42
-
-
Lockhart, P.J.1
Kachergus, J.2
Lincoln, S.3
-
24
-
-
0028909113
-
Monte Carlo tests for associations between disease and alleles at highly polymorphic loci
-
Sham PC, Curtis D. Monte Carlo tests for associations between disease and alleles at highly polymorphic loci. Ann Hum Genet 1995 59 : 97 105.
-
(1995)
Ann Hum Genet
, vol.59
, pp. 97-105
-
-
Sham, P.C.1
Curtis, D.2
-
25
-
-
18444369013
-
The structure of haplotype blocks in the human genome
-
Gabriel SB, Schaffner SF, Nguyen H et al. The structure of haplotype blocks in the human genome. Science 2002 296 : 2225 9.
-
(2002)
Science
, vol.296
, pp. 2225-9
-
-
Gabriel, S.B.1
Schaffner, S.F.2
Nguyen, H.3
-
26
-
-
13844270527
-
Accounting for decay of linkage disequilibrium in haplotype inference and missing-data imputation
-
Stephens M, Scheet P. Accounting for decay of linkage disequilibrium in haplotype inference and missing-data imputation. Am J Hum Genet 2005 76 : 449 62.
-
(2005)
Am J Hum Genet
, vol.76
, pp. 449-62
-
-
Stephens, M.1
Scheet, P.2
-
27
-
-
0036284203
-
Testing association of statistically inferred haplotypes with discrete and continuous traits in samples of unrelated individuals
-
Zaykin DV, Westfall PH, Young SS, Karnoub MA, Wagner MJ, Ehm MG. Testing association of statistically inferred haplotypes with discrete and continuous traits in samples of unrelated individuals. Hum Hered 2002 53 : 79 91.
-
(2002)
Hum Hered
, vol.53
, pp. 79-91
-
-
Zaykin, D.V.1
Westfall, P.H.2
Young, S.S.3
Karnoub, M.A.4
Wagner, M.J.5
Ehm, M.G.6
-
28
-
-
0035894661
-
Effect of allelic variation at the NACP-Rep1 repeat upstream of the alpha-synuclein gene (SNCA) on transcription in a cell culture luciferase reporter system
-
Chiba-Falek O, Nussbaum RL. Effect of allelic variation at the NACP-Rep1 repeat upstream of the alpha-synuclein gene (SNCA) on transcription in a cell culture luciferase reporter system. Hum Mol Genet 2001 10 : 3101 9.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 3101-9
-
-
Chiba-Falek, O.1
Nussbaum, R.L.2
-
29
-
-
0142070814
-
Functional analysis of intra-allelic variation at NACP-Rep1 in the alpha-synuclein gene
-
Chiba-Falek O, Touchman JW, Nussbaum RL. Functional analysis of intra-allelic variation at NACP-Rep1 in the alpha-synuclein gene. Hum Genet 2003 113 : 426 31.
-
(2003)
Hum Genet
, vol.113
, pp. 426-31
-
-
Chiba-Falek, O.1
Touchman, J.W.2
Nussbaum, R.L.3
-
30
-
-
0028618190
-
Tissue-dependent alternative splicing of mRNA for NACP, the precursor of non-A beta component of Alzheimer's disease amyloid
-
Ueda K, Saitoh T, Mori H. Tissue-dependent alternative splicing of mRNA for NACP, the precursor of non-A beta component of Alzheimer's disease amyloid. Biochem Biophys Res Commun 1994 205 : 1366 72.
-
(1994)
Biochem Biophys Res Commun
, vol.205
, pp. 1366-72
-
-
Ueda, K.1
Saitoh, T.2
Mori, H.3
|