-
1
-
-
0033656672
-
A high fasting plasma insulin concentration predicts type 2 diabetes independent of insulin resistance. evidence for a pathogenic role of relative hyperinsulinemia
-
Weyer C, Hanson RL, Tataranni PA, Bogardus C, Pratley RE (2000) A high fasting plasma insulin concentration predicts type 2 diabetes independent of insulin resistance. evidence for a pathogenic role of relative hyperinsulinemia. Diabetes 49: 2094-2101.
-
(2000)
Diabetes
, vol.49
, pp. 2094-2101
-
-
Weyer, C.1
Hanson, R.L.2
Tataranni, P.A.3
Bogardus, C.4
Pratley, R.E.5
-
2
-
-
68149091969
-
Basal-state hyperinsulinemia in healthy normoglycemic adults is predictive of type 2 diabetes over a 24-year follow-up
-
Dankner R, Chetrit A, Shanik MH, Raz I, Roth J (2009) Basal-state hyperinsulinemia in healthy normoglycemic adults is predictive of type 2 diabetes over a 24-year follow-up. Diabetes Care 32: 1464-1466.
-
(2009)
Diabetes Care
, vol.32
, pp. 1464-1466
-
-
Dankner, R.1
Chetrit, A.2
Shanik, M.H.3
Raz, I.4
Roth, J.5
-
3
-
-
78649904633
-
Hyperinsulinemia and metabolic syndrome at mean age of 10 years in black and white schoolgirls and development of impaired fasting glucose and type 2 diabetes mellitus by mean age of 24 years
-
Morrison JA, Glueck CJ, Umar M, Daniels S, Dolan LM, Wang P (2011) Hyperinsulinemia and metabolic syndrome at mean age of 10 years in black and white schoolgirls and development of impaired fasting glucose and type 2 diabetes mellitus by mean age of 24 years. Metabolism 60: 24-31.
-
(2011)
Metabolism
, vol.60
, pp. 24-31
-
-
Morrison, J.A.1
Glueck, C.J.2
Umar, M.3
Daniels, S.4
Dolan, L.M.5
Wang, P.6
-
4
-
-
0028314008
-
Hyperinsulinemia induces a reversible impairment in insulin receptor function leading to diabetes in the sand rat model of non-insulin-dependent diabetes mellitus
-
Kanety H, Moshe S, Shafrir E, Lunenfeld B, Karasik A (1994) Hyperinsulinemia induces a reversible impairment in insulin receptor function leading to diabetes in the sand rat model of non-insulin-dependent diabetes mellitus. Proc Natl Acad Sci USA 91: 1853-1857.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 1853-1857
-
-
Kanety, H.1
Moshe, S.2
Shafrir, E.3
Lunenfeld, B.4
Karasik, A.5
-
5
-
-
0029988850
-
Development and consequences of insulin resistance: lessons from animals with hyperinsulinaemia
-
Shafrir E (1996) Development and consequences of insulin resistance: lessons from animals with hyperinsulinaemia. Diabetes Metab 22: 122-131.
-
(1996)
Diabetes Metab
, vol.22
, pp. 122-131
-
-
Shafrir, E.1
-
6
-
-
16844370268
-
Regulation of insulin signalling by hyperinsulinaemia: role of IRS-1/2 serine phosphorylation and the mTOR/p70 S6K pathway
-
Ueno M, Carvalheira JBC, Tambascia RC, Bezerra RMN, Amaral ME, Carneiro EM, Folli F, Franchini KG, Saad MJA (2005) Regulation of insulin signalling by hyperinsulinaemia: role of IRS-1/2 serine phosphorylation and the mTOR/p70 S6K pathway. Diabetologia 48: 506-518.
-
(2005)
Diabetologia
, vol.48
, pp. 506-518
-
-
Ueno, M.1
Carvalheira, J.B.C.2
Tambascia, R.C.3
Bezerra, R.M.N.4
Amaral, M.E.5
Carneiro, E.M.6
Folli, F.7
Franchini, K.G.8
Saad, M.J.A.9
-
7
-
-
41149159084
-
Insulin resistance and hyperinsulinemia. Is hyperinsulinemia the cart or the horse?
-
Shanik MH, Xu Y, Skrha J, Dankner R, Zick Y, Roth J (2008) Insulin resistance and hyperinsulinemia. Is hyperinsulinemia the cart or the horse? Diabetes Care 31(Suppl. 2): S262-S268.
-
(2008)
Diabetes Care
, vol.31
, Issue.SUPPL. 2
-
-
Shanik, M.H.1
Xu, Y.2
Skrha, J.3
Dankner, R.4
Zick, Y.5
Roth, J.6
-
8
-
-
0038521284
-
Phosphoinositide 3-kinase-mediated reduction of insulin receptor substrate-1/2 protein expression via different mechanisms contributes to the insulin-induced desensitization of its signaling pathways in L6 muscle cells
-
Pirola L, Bonnafous S, Johnston AM, Chaussade C, Portis F, Obberghen EV (2003) Phosphoinositide 3-kinase-mediated reduction of insulin receptor substrate-1/2 protein expression via different mechanisms contributes to the insulin-induced desensitization of its signaling pathways in L6 muscle cells. J Biol Chem 278: 15641-15651.
-
(2003)
J Biol Chem
, vol.278
, pp. 15641-15651
-
-
Pirola, L.1
Bonnafous, S.2
Johnston, A.M.3
Chaussade, C.4
Portis, F.5
Obberghen, E.V.6
-
9
-
-
79959933430
-
Hyperinsulinemia leads to uncoupled insulin regulation of the GLUT4 glucose transporter and the FoxO1 transcription factor
-
Gonzaleza E, Fliera E, Mollea D, Accilib D, McGrawa TE (2011) Hyperinsulinemia leads to uncoupled insulin regulation of the GLUT4 glucose transporter and the FoxO1 transcription factor. Proc Natl Acad Sci U S A 108: 10162-10167.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 10162-10167
-
-
Gonzaleza, E.1
Fliera, E.2
Mollea, D.3
Accilib, D.4
McGrawa, T.E.5
-
10
-
-
0019762341
-
The effect of insulin on the disposal of intravenous glucose. Results from indirect calorimetry and hepatic and femoral venous catheterization
-
DeFronzo RA, Jacot E, Jequier E, Maeder E, Wahren J, Felber JP (1981) The effect of insulin on the disposal of intravenous glucose. Results from indirect calorimetry and hepatic and femoral venous catheterization. Diabetes 30: 1000-1007.
-
(1981)
Diabetes
, vol.30
, pp. 1000-1007
-
-
Defronzo, R.A.1
Jacot, E.2
Jequier, E.3
Maeder, E.4
Wahren, J.5
Felber, J.P.6
-
11
-
-
0035856949
-
Insulin signaling and the regulation of glucose and lipid metabolism
-
Saltiel AR, Kahn CR (2001) Insulin signaling and the regulation of glucose and lipid metabolism. Nature 414: 799-806.
-
(2001)
Nature
, vol.414
, pp. 799-806
-
-
Saltiel, A.R.1
Kahn, C.R.2
-
12
-
-
63849273089
-
AMP-activated protein kinase and muscle insulin resistance
-
Kraegen EW, Bruce C, Hegarty BD, Ye JM, Turner N, Cooney GJ (2009) AMP-activated protein kinase and muscle insulin resistance. Front Biosci 14: 4658-4672.
-
(2009)
Front Biosci
, vol.14
, pp. 4658-4672
-
-
Kraegen, E.W.1
Bruce, C.2
Hegarty, B.D.3
Ye, J.M.4
Turner, N.5
Cooney, G.J.6
-
13
-
-
0031849916
-
Evidence for 5′ AMP-activated protein kinase mediation of the effect of muscle contraction on glucose transport
-
Hayashi T, Hirshman MF, Kurth EJ, Winder WW, Goodyear LJ (1998) Evidence for 5′ AMP-activated protein kinase mediation of the effect of muscle contraction on glucose transport. Diabetes 47: 1369-1373.
-
(1998)
Diabetes
, vol.47
, pp. 1369-1373
-
-
Hayashi, T.1
Hirshman, M.F.2
Kurth, E.J.3
Winder, W.W.4
Goodyear, L.J.5
-
14
-
-
33846547759
-
Flavonoid content of US fruits, vegetables, and nuts
-
Harnly JM, Doherty RF, Beecher GR, Holden JM, Haytowitz DB, Bhagwat S, Gebhardt S (2006) Flavonoid content of US fruits, vegetables, and nuts. J Agric Food Chem 54: 9966-9977.
-
(2006)
J Agric Food Chem
, vol.54
, pp. 9966-9977
-
-
Harnly, J.M.1
Doherty, R.F.2
Beecher, G.R.3
Holden, J.M.4
Haytowitz, D.B.5
Bhagwat, S.6
Gebhardt, S.7
-
15
-
-
0028791074
-
Phytochemical investigations of Licania genus. Flavonoids and triterpenoids from Licania pittieri
-
Mendez J, Bilia AR, Morelli I (1995) Phytochemical investigations of Licania genus. Flavonoids and triterpenoids from Licania pittieri. Pharm Acta Helv 70: 223-226.
-
(1995)
Pharm Acta Helv
, vol.70
, pp. 223-226
-
-
Mendez, J.1
Bilia, A.R.2
Morelli, I.3
-
16
-
-
34047106057
-
Plants and their active constituents from South, Central, and North America with hypoglycemic activity
-
Barbosa-Filho JM, Vasconcelos THC, Alencar AA, Batista LM, Oliveira RAG, Guedes DN, Falcao HS, Moura MD, Diniz MFFM, Modesto-Filho J (2005) Plants and their active constituents from South, Central, and North America with hypoglycemic activity. Rev Bras Farmacogn 15: 392-413.
-
(2005)
Rev Bras Farmacogn
, vol.15
, pp. 392-413
-
-
Barbosa-Filho, J.M.1
Vasconcelos, T.H.C.2
Alencar, A.A.3
Batista, L.M.4
Oliveira, R.A.G.5
Guedes, D.N.6
Falcao, H.S.7
Moura, M.D.8
Diniz, M.F.F.M.9
Modesto-Filho, J.10
-
17
-
-
0036721149
-
Flavonoid intake and risk of chronic diseases
-
Knekt P, Kumpulainen J, Jarvinen R, Rissanen H, Heliovaara M, Reunanen A, Hakulinen T, Aromaa A (2002) Flavonoid intake and risk of chronic diseases. Am J Clin Nutr 76: 560-568.
-
(2002)
Am J Clin Nutr
, vol.76
, pp. 560-568
-
-
Knekt, P.1
Kumpulainen, J.2
Jarvinen, R.3
Rissanen, H.4
Heliovaara, M.5
Reunanen, A.6
Hakulinen, T.7
Aromaa, A.8
-
18
-
-
0034714436
-
Effects of myricetin on glycemia and glycogen metabolism in diabetic rats
-
Ong KC, Khoo HE (2000) Effects of myricetin on glycemia and glycogen metabolism in diabetic rats. Life Sci 67: 1695-1705.
-
(2000)
Life Sci
, vol.67
, pp. 1695-1705
-
-
Ong, K.C.1
Khoo, H.E.2
-
19
-
-
23644438869
-
Myricetin as the active principle of Abelmoschus moschatus to lower plasma glucose in streptozotocin-induced diabetic rats
-
Liu IM, Liou SS, Lan TW, Hsu FL, Cheng JT (2005) Myricetin as the active principle of Abelmoschus moschatus to lower plasma glucose in streptozotocin-induced diabetic rats. Planta Med 71: 617-621.
-
(2005)
Planta Med
, vol.71
, pp. 617-621
-
-
Liu, I.M.1
Liou, S.S.2
Lan, T.W.3
Hsu, F.L.4
Cheng, J.T.5
-
20
-
-
36048945645
-
Myricetin, a naturally occurring flavonol, ameliorates insulin resistance induced by a high-fructose diet in rats
-
Liu IM, Tzeng TF, Liou SS, Lan TW (2007) Myricetin, a naturally occurring flavonol, ameliorates insulin resistance induced by a high-fructose diet in rats. Life Sci 81: 1479-1488.
-
(2007)
Life Sci
, vol.81
, pp. 1479-1488
-
-
Liu, I.M.1
Tzeng, T.F.2
Liou, S.S.3
Lan, T.W.4
-
21
-
-
34548614885
-
Improvement of insulin sensitivity in obese Zucker rats by myricetin extracted from Abelmoschus moschatus
-
Liu IM, Tzeng TF, Liou SS, Lan TW (2007) Improvement of insulin sensitivity in obese Zucker rats by myricetin extracted from Abelmoschus moschatus. Planta Med 73: 1054-1060.
-
(2007)
Planta Med
, vol.73
, pp. 1054-1060
-
-
Liu, I.M.1
Tzeng, T.F.2
Liou, S.S.3
Lan, T.W.4
-
22
-
-
80052707704
-
Myricetin ameliorates defective post-receptor insulin signaling via β-endorphin signaling in the skeletal muscles of fructose-fed rats
-
Tzeng TF, Liou SS, Liu IM (2011) Myricetin ameliorates defective post-receptor insulin signaling via β-endorphin signaling in the skeletal muscles of fructose-fed rats. Evid Based Complement Alternat Med 2011: 150752.
-
(2011)
Evid Based Complement Alternat Med
, vol.2011
, pp. 150752
-
-
Tzeng, T.F.1
Liou, S.S.2
Liu, I.M.3
-
23
-
-
70649084038
-
Epigallocatechin-3-O-gallate (EGCG) protects the insulin sensitivity in rat L6 muscle cells exposed to dexamethasone condition
-
Zhang ZF, Li Q, Liang J, Dai XQ, Ding Y, Wang JB, Li Y (2010) Epigallocatechin-3-O-gallate (EGCG) protects the insulin sensitivity in rat L6 muscle cells exposed to dexamethasone condition. Phytomedicine 17: 14-18.
-
(2010)
Phytomedicine
, vol.17
, pp. 14-18
-
-
Zhang, Z.F.1
Li, Q.2
Liang, J.3
Dai, X.Q.4
Ding, Y.5
Wang, J.B.6
Li, Y.7
-
24
-
-
0030048414
-
Insulinomimetic effects of myricetin on lipogenesis and glucose transportin rat adipocytes but not glucose transport translocation
-
Ong KC, Khoo HE (1996) Insulinomimetic effects of myricetin on lipogenesis and glucose transportin rat adipocytes but not glucose transport translocation. Biochem Pharmacol 51: 423-429.
-
(1996)
Biochem Pharmacol
, vol.51
, pp. 423-429
-
-
Ong, K.C.1
Khoo, H.E.2
-
25
-
-
33846803914
-
Inhibition of the intestinal glucose transporter GLUT2 by flavonoids
-
Kwon O, Eck P, Chen S, Corpe CP, Lee JH, Kruhlak M, Levine M (2007) Inhibition of the intestinal glucose transporter GLUT2 by flavonoids. FASEB J 21: 366-377.
-
(2007)
FASEB J
, vol.21
, pp. 366-377
-
-
Kwon, O.1
Eck, P.2
Chen, S.3
Corpe, C.P.4
Lee, J.H.5
Kruhlak, M.6
Levine, M.7
-
26
-
-
70350495376
-
Inulin increases glucose transport in C2C12 myotubes and HepG2 cells via activation of AMP-activated protein kinase and phosphatidylinositol 3-kinase pathways
-
Yun H, Lee JH, Park CE, Kim MJ, Min BI, Bae H, Choe W, Kang I, Kim SS, Ha J (2009) Inulin increases glucose transport in C2C12 myotubes and HepG2 cells via activation of AMP-activated protein kinase and phosphatidylinositol 3-kinase pathways. J Med Food 12: 1023-1028.
-
(2009)
J Med Food
, vol.12
, pp. 1023-1028
-
-
Yun, H.1
Lee, J.H.2
Park, C.E.3
Kim, M.J.4
Min, B.I.5
Bae, H.6
Choe, W.7
Kang, I.8
Kim, S.S.9
Ha, J.10
-
27
-
-
34247600642
-
Resveratrol stimulates glucose transport in C2C12 myotubes by activating AMP-activated protein kinase
-
Park CE, Kim MJ, Lee JH, Min BI, Bae H, Choe W, Kim SS, Ha J (2007) Resveratrol stimulates glucose transport in C2C12 myotubes by activating AMP-activated protein kinase. Exp Mol Med 39: 222-229.
-
(2007)
Exp Mol Med
, vol.39
, pp. 222-229
-
-
Park, C.E.1
Kim, M.J.2
Lee, J.H.3
Min, B.I.4
Bae, H.5
Choe, W.6
Kim, S.S.7
Ha, J.8
-
28
-
-
63849125267
-
Insulin resistance and fuel homeostasis: the role of AMP-activated protein kinase
-
Hegarty BD, Turner N, Cooney GJ, Kraegen EW (2009) Insulin resistance and fuel homeostasis: the role of AMP-activated protein kinase. Acta Physiol 196: 129-145.
-
(2009)
Acta Physiol
, vol.196
, pp. 129-145
-
-
Hegarty, B.D.1
Turner, N.2
Cooney, G.J.3
Kraegen, E.W.4
-
29
-
-
20044370885
-
Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction
-
Sakamoto K, Mccarthy A, Smith D, Green KA, Grahame Hardie D, Ashworth A, Alessi D (2005) Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction. EMBO J 24: 1810-1820.
-
(2005)
EMBO J
, vol.24
, pp. 1810-1820
-
-
Sakamoto, K.1
McUarthy, A.2
Smith, D.3
Green, K.A.4
Grahame Hardie, D.5
Ashworth, A.6
Alessi, D.7
-
30
-
-
28844433635
-
The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin
-
Shaw RJ, Lamia KA, Vasquez D, Koo S, Bardeesy N, Depinho RA, Montminy M, Cantley LC (2005) The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin. Science 310: 1642-1646.
-
(2005)
Science
, vol.310
, pp. 1642-1646
-
-
Shaw, R.J.1
Lamia, K.A.2
Vasquez, D.3
Koo, S.4
Bardeesy, N.5
Depinho, R.A.6
Montminy, M.7
Cantley, L.C.8
-
31
-
-
35848970056
-
Theaflavins attenuate hepatic lipid accumulation through activating AMPK in human HepG2 cells
-
Lin CL, Huang HC, Lin JK (2007) Theaflavins attenuate hepatic lipid accumulation through activating AMPK in human HepG2 cells. J Lipid Res 48: 2334-2343.
-
(2007)
J Lipid Res
, vol.48
, pp. 2334-2343
-
-
Lin, C.L.1
Huang, H.C.2
Lin, J.K.3
|