-
1
-
-
56749164791
-
Nutrient sensing and inflammation in metabolic diseases
-
Hotamisligil GS, Erbay E. Nutrient sensing and inflammation in metabolic diseases. Nat Rev Immunol 2008; 8: 923-934.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 923-934
-
-
Hotamisligil, G.S.1
Erbay, E.2
-
2
-
-
0018864840
-
Regulation of hepatic fatty acid oxidation and ketone body production
-
McGarry JD, Foster DW. Regulation of hepatic fatty acid oxidation and ketone body production. Annu Rev Biochem 1980; 49: 395-420.
-
(1980)
Annu Rev Biochem
, vol.49
, pp. 395-420
-
-
McGarry, J.D.1
Foster, D.W.2
-
3
-
-
38449111332
-
Splanchnic regulation of glucose production
-
Wahren J, Ekberg K. Splanchnic regulation of glucose production. Annu Rev Nutr 2007; 27: 329-345.
-
(2007)
Annu Rev Nutr
, vol.27
, pp. 329-345
-
-
Wahren, J.1
Ekberg, K.2
-
4
-
-
70350322694
-
Fibroblast growth factor 21-deficient mice demonstrate impaired adaptation to ketosis
-
Badman MK, Koester A, Flier JS, Kharitonenkov A, Maratos-Flier E. Fibroblast growth factor 21-deficient mice demonstrate impaired adaptation to ketosis. Endocrinology 2009; 150: 4931-4940.
-
(2009)
Endocrinology
, vol.150
, pp. 4931-4940
-
-
Badman, M.K.1
Koester, A.2
Flier, J.S.3
Kharitonenkov, A.4
Maratos-Flier, E.5
-
5
-
-
0033305213
-
Peroxisome proliferator-activated receptors: nuclear control of metabolism
-
Desvergne B, Wahli W. Peroxisome proliferator-activated receptors: nuclear control of metabolism. Endocr Rev 1999; 20: 649-688.
-
(1999)
Endocr Rev
, vol.20
, pp. 649-688
-
-
Desvergne, B.1
Wahli, W.2
-
6
-
-
77954987061
-
PPARalpha: energy combustion, hypolipidemia, inflammation, and cancer
-
Pyper SR, Viswakarma N, Yu S, Reddy JK. PPARalpha: energy combustion, hypolipidemia, inflammation, and cancer. Nucl Recept Signal 2010; 8: e002.
-
(2010)
Nucl Recept Signal
, vol.8
-
-
Pyper, S.R.1
Viswakarma, N.2
Yu, S.3
Reddy, J.K.4
-
7
-
-
79952227694
-
Nuclear receptors in liver disease
-
Wagner M, Zollner G, Trauner M. Nuclear receptors in liver disease. HEPATOLOGY 2011; 53: 1023-1034.
-
(2011)
HEPATOLOGY
, vol.53
, pp. 1023-1034
-
-
Wagner, M.1
Zollner, G.2
Trauner, M.3
-
8
-
-
71949101616
-
Peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) but not PPARalpha serves as a plasma free fatty acid sensor in liver
-
Sanderson LM, Degenhardt T, Koppen A, Kalkhoven E, Desvergne B, Muller M, Kersten S. Peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) but not PPARalpha serves as a plasma free fatty acid sensor in liver. Mol Cell Biol 2009; 29: 6257-6267.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 6257-6267
-
-
Sanderson, L.M.1
Degenhardt, T.2
Koppen, A.3
Kalkhoven, E.4
Desvergne, B.5
Muller, M.6
Kersten, S.7
-
9
-
-
0028180070
-
mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer
-
Tontonoz P, Hu E, Graves RA, Budavari AI, Spiegelman BM. mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer. Genes Dev 1994; 8: 1224-1234.
-
(1994)
Genes Dev
, vol.8
, pp. 1224-1234
-
-
Tontonoz, P.1
Hu, E.2
Graves, R.A.3
Budavari, A.I.4
Spiegelman, B.M.5
-
10
-
-
78650848337
-
mTORC1 controls fasting-induced ketogenesis and its modulation by ageing
-
Sengupta S, Peterson TR, Laplante M, Oh S, Sabatini DM. mTORC1 controls fasting-induced ketogenesis and its modulation by ageing. Nature 2010; 468: 1100-1104.
-
(2010)
Nature
, vol.468
, pp. 1100-1104
-
-
Sengupta, S.1
Peterson, T.R.2
Laplante, M.3
Oh, S.4
Sabatini, D.M.5
-
11
-
-
4544220704
-
Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity
-
Um SH, Frigerio F, Watanabe M, Picard F, Joaquin M, Sticker M, et al. Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity. Nature 2004; 431: 200-205.
-
(2004)
Nature
, vol.431
, pp. 200-205
-
-
Um, S.H.1
Frigerio, F.2
Watanabe, M.3
Picard, F.4
Joaquin, M.5
Sticker, M.6
-
12
-
-
33744505375
-
Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1
-
Um SH, D'Alessio D, Thomas G. Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1. Cell Metab 2006; 3: 393-402.
-
(2006)
Cell Metab
, vol.3
, pp. 393-402
-
-
Um, S.H.1
D'Alessio, D.2
Thomas, G.3
-
13
-
-
33846806078
-
Elevated sensitivity to diet-induced obesity and insulin resistance in mice lacking 4E-BP1 and 4E-BP2
-
Le Bacquer O, Petroulakis E, Paglialunga S, Poulin F, Richard D, Cianflone K, Sonenberg N. Elevated sensitivity to diet-induced obesity and insulin resistance in mice lacking 4E-BP1 and 4E-BP2. J Clin Invest 2007; 117: 387-396.
-
(2007)
J Clin Invest
, vol.117
, pp. 387-396
-
-
Le Bacquer, O.1
Petroulakis, E.2
Paglialunga, S.3
Poulin, F.4
Richard, D.5
Cianflone, K.6
Sonenberg, N.7
-
14
-
-
0032514924
-
Molecular cloning and characterization of a novel p70 S6 kinase, p70 S6 kinase beta containing a proline-rich region
-
Gout I, Minami T, Hara K, Tsujishita Y, Filonenko V, Waterfield MD, Yonezawa K. Molecular cloning and characterization of a novel p70 S6 kinase, p70 S6 kinase beta containing a proline-rich region. J Biol Chem 1998; 273: 30061-30064.
-
(1998)
J Biol Chem
, vol.273
, pp. 30061-30064
-
-
Gout, I.1
Minami, T.2
Hara, K.3
Tsujishita, Y.4
Filonenko, V.5
Waterfield, M.D.6
Yonezawa, K.7
-
15
-
-
0032538890
-
Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase
-
Shima H, Pende M, Chen Y, Fumagalli S, Thomas G, Kozma SC. Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase. EMBO J 1998; 17: 6649-6659.
-
(1998)
EMBO J
, vol.17
, pp. 6649-6659
-
-
Shima, H.1
Pende, M.2
Chen, Y.3
Fumagalli, S.4
Thomas, G.5
Kozma, S.C.6
-
16
-
-
0033539048
-
Cloning and characterization of a nuclear S6 kinase, S6 kinase-related kinase (SRK); a novel nuclear target of Akt
-
Koh H, Jee K, Lee B, Kim J, Kim D, Yun YH, et al. Cloning and characterization of a nuclear S6 kinase, S6 kinase-related kinase (SRK); a novel nuclear target of Akt. Oncogene 1999; 18: 5115-5119.
-
(1999)
Oncogene
, vol.18
, pp. 5115-5119
-
-
Koh, H.1
Jee, K.2
Lee, B.3
Kim, J.4
Kim, D.5
Yun, Y.H.6
-
17
-
-
0037307316
-
Protein kinase C phosphorylates ribosomal protein S6 kinase betaII and regulates its subcellular localization
-
Valovka T, Verdier F, Cramer R, Zhyvoloup A, Fenton T, Rebholz H, et al. Protein kinase C phosphorylates ribosomal protein S6 kinase betaII and regulates its subcellular localization. Mol Cell Biol 2003; 23: 852-863.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 852-863
-
-
Valovka, T.1
Verdier, F.2
Cramer, R.3
Zhyvoloup, A.4
Fenton, T.5
Rebholz, H.6
-
18
-
-
11144356304
-
S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5′-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway
-
Pende M, Um SH, Mieulet V, Sticker M, Goss VL, Mestan J, et al. S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5′-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway. Mol Cell Biol 2004; 24: 3112-3124.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 3112-3124
-
-
Pende, M.1
Um, S.H.2
Mieulet, V.3
Sticker, M.4
Goss, V.L.5
Mestan, J.6
-
19
-
-
77957959354
-
Hepatitis B virus X protein impairs hepatic insulin signaling through degradation of IRS1 and induction of SOCS3
-
Kim K, Kim KH, Cheong J. Hepatitis B virus X protein impairs hepatic insulin signaling through degradation of IRS1 and induction of SOCS3. PLoS One 2010; 5: e8649.
-
(2010)
PLoS One
, vol.5
-
-
Kim, K.1
Kim, K.H.2
Cheong, J.3
-
20
-
-
0032699670
-
Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting
-
Kersten S, Seydoux J, Peters JM, Gonzalez FJ, Desvergne B, Wahli W. Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting. J Clin Invest 1999; 103: 1489-1498.
-
(1999)
J Clin Invest
, vol.103
, pp. 1489-1498
-
-
Kersten, S.1
Seydoux, J.2
Peters, J.M.3
Gonzalez, F.J.4
Desvergne, B.5
Wahli, W.6
-
21
-
-
13844262924
-
Corepressors selectively control the transcriptional activity of PPARgamma in adipocytes
-
Guan HP, Ishizuka T, Chui PC, Lehrke M, Lazar MA. Corepressors selectively control the transcriptional activity of PPARgamma in adipocytes. Genes Dev 2005; 19: 453-461.
-
(2005)
Genes Dev
, vol.19
, pp. 453-461
-
-
Guan, H.P.1
Ishizuka, T.2
Chui, P.C.3
Lehrke, M.4
Lazar, M.A.5
-
22
-
-
0031468588
-
A role for estrogen-related receptor alpha in the control of mitochondrial fatty acid beta-oxidation during brown adipocyte differentiation
-
Vega RB, Kelly DP. A role for estrogen-related receptor alpha in the control of mitochondrial fatty acid beta-oxidation during brown adipocyte differentiation. J Biol Chem 1997; 272: 31693-31699.
-
(1997)
J Biol Chem
, vol.272
, pp. 31693-31699
-
-
Vega, R.B.1
Kelly, D.P.2
-
23
-
-
26444484528
-
Fatty acids induce L-CPT I gene expression through a PPARalpha-independent mechanism in rat hepatoma cells
-
Le May C, Cauzac M, Diradourian C, Perdereau D, Girard J, Burnol AF, Pegorier JP. Fatty acids induce L-CPT I gene expression through a PPARalpha-independent mechanism in rat hepatoma cells. J Nutr 2005; 135: 2313-2319.
-
(2005)
J Nutr
, vol.135
, pp. 2313-2319
-
-
Le May, C.1
Cauzac, M.2
Diradourian, C.3
Perdereau, D.4
Girard, J.5
Burnol, A.F.6
Pegorier, J.P.7
-
24
-
-
0033594980
-
A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders
-
Leone TC, Weinheimer CJ, Kelly DP. A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders. Proc Natl Acad Sci U S A 1999; 96: 7473-7478.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 7473-7478
-
-
Leone, T.C.1
Weinheimer, C.J.2
Kelly, D.P.3
-
25
-
-
77952618580
-
Progressive adaptation of hepatic ketogenesis in mice fed a high-fat diet
-
Sunny NE, Satapati S, Fu X, He T, Mehdibeigi R, Spring-Robinson C, et al. Progressive adaptation of hepatic ketogenesis in mice fed a high-fat diet. Am J Physiol Endocrinol Metab 2010; 298: E1226-E1235.
-
(2010)
Am J Physiol Endocrinol Metab
, vol.298
-
-
Sunny, N.E.1
Satapati, S.2
Fu, X.3
He, T.4
Mehdibeigi, R.5
Spring-Robinson, C.6
-
26
-
-
33750110683
-
Fuel metabolism in starvation
-
Cahill GFJr., Fuel metabolism in starvation. Annu Rev Nutr 2006; 26: 1-22.
-
(2006)
Annu Rev Nutr
, vol.26
, pp. 1-22
-
-
Cahill Jr., G.F.1
-
27
-
-
29244436681
-
AMPK activation increases fatty acid oxidation in skeletal muscle by activating PPARalpha and PGC-1
-
Lee WJ, Kim M, Park HS, Kim HS, Jeon MJ, Oh KS, et al. AMPK activation increases fatty acid oxidation in skeletal muscle by activating PPARalpha and PGC-1. Biochem Biophys Res Commun 2006; 340: 291-295.
-
(2006)
Biochem Biophys Res Commun
, vol.340
, pp. 291-295
-
-
Lee, W.J.1
Kim, M.2
Park, H.S.3
Kim, H.S.4
Jeon, M.J.5
Oh, K.S.6
-
28
-
-
59649097612
-
The ubiquitination of ribosomal S6 kinases is independent from the mitogen-induced phosphorylation/activation of the kinase
-
Gwalter J, Wang ML, Gout I. The ubiquitination of ribosomal S6 kinases is independent from the mitogen-induced phosphorylation/activation of the kinase. Int J Biochem Cell Biol 2009; 41: 828-833.
-
(2009)
Int J Biochem Cell Biol
, vol.41
, pp. 828-833
-
-
Gwalter, J.1
Wang, M.L.2
Gout, I.3
-
29
-
-
34249727164
-
Transcriptional coregulators in the control of energy homeostasis
-
Feige JN, Auwerx J. Transcriptional coregulators in the control of energy homeostasis. Trends Cell Biol 2007; 17: 292-301.
-
(2007)
Trends Cell Biol
, vol.17
, pp. 292-301
-
-
Feige, J.N.1
Auwerx, J.2
-
30
-
-
77952761603
-
Involvement of heterogeneous ribonucleoprotein F in the regulation of cell proliferation via the mammalian target of rapamycin/S6 kinase 2 pathway
-
Goh ET, Pardo OE, Michael N, Niewiarowski A, Totty N, Volkova D, et al. Involvement of heterogeneous ribonucleoprotein F in the regulation of cell proliferation via the mammalian target of rapamycin/S6 kinase 2 pathway. J Biol Chem 2010; 285: 17065-17076.
-
(2010)
J Biol Chem
, vol.285
, pp. 17065-17076
-
-
Goh, E.T.1
Pardo, O.E.2
Michael, N.3
Niewiarowski, A.4
Totty, N.5
Volkova, D.6
-
31
-
-
0034680797
-
Glucose down-regulates the expression of the peroxisome proliferator-activated receptor-alpha gene in the pancreatic beta-cell
-
Roduit R, Morin J, Masse F, Segall L, Roche E, Newgard CB, et al. Glucose down-regulates the expression of the peroxisome proliferator-activated receptor-alpha gene in the pancreatic beta-cell. J Biol Chem 2000; 275: 35799-35806.
-
(2000)
J Biol Chem
, vol.275
, pp. 35799-35806
-
-
Roduit, R.1
Morin, J.2
Masse, F.3
Segall, L.4
Roche, E.5
Newgard, C.B.6
-
32
-
-
33745662623
-
Clofibrate treatment promotes branched-chain amino acid catabolism and decreases the phosphorylation state of mTOR, eIF4E-BP1, and S6K1 in rat liver
-
Ishiguro H, Katano Y, Nakano I, Ishigami M, Hayashi K, Honda T, et al. Clofibrate treatment promotes branched-chain amino acid catabolism and decreases the phosphorylation state of mTOR, eIF4E-BP1, and S6K1 in rat liver. Life Sci 2006; 79: 737-743.
-
(2006)
Life Sci
, vol.79
, pp. 737-743
-
-
Ishiguro, H.1
Katano, Y.2
Nakano, I.3
Ishigami, M.4
Hayashi, K.5
Honda, T.6
|