Selective regression of cancer cells expressing a splicing variant of AIMP2 through targeted RNA replacement by trans-splicing ribozyme

Journal of Biotechnology

Volumn 158, Issue 1-2, 2012, Pages 44-49

  Won, You Sub ^a   Lee, Seong Wook ^a  

^a Dankook University   (South Korea)

Author keywords

AIMP2 DX2; Alternative splicing; Cancer gene therapy; Group I intron; RNA replacement; Trans splicing ribozyme

Indexed keywords

AIMP2-DX2; ALTERNATIVE SPLICING; CANCER GENE THERAPY; GROUP I INTRON; TRANS-SPLICING;

BIOLOGICAL ORGANS; CELL DEATH; DISEASES; GENES; TISSUE;

RNA;

AMINOACYL TRNA SYNTHETASE INTERACTING MULTIFUNCTIONAL PROTEIN 2; PEPTIDE DERIVATIVE; RIBOZYME; RNA; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CANCER GENE THERAPY; CANCER GROWTH; CANCER REGRESSION; CONTROLLED STUDY; GENE DELIVERY SYSTEM; HUMAN; HUMAN CELL; LUNG CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; SUICIDE GENE; TRANS SPLICING;

ALTERNATIVE SPLICING; APOPTOSIS; CELL LINE, TUMOR; CYTOKINES; EXONS; GENES, TRANSGENIC, SUICIDE; HUMANS; LUNG NEOPLASMS; MOLECULAR TARGETED THERAPY; NEOPLASM PROTEINS; RNA, CATALYTIC; RNA-BINDING PROTEINS; TRANS-SPLICING; TRANSFECTION;

EID: 84862826238     PISSN: 01681656     EISSN: 18734863     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2012.01.006     Document Type: Article

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